- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
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Travel Information
Compare bus and train for Florence, SC to Greenville, SC
Omio recommends booking the train as it is the most popular option from Florence, SC to Greenville, SC among Omio's users. If you are prioritising price take the train with prices starting from $156. For those with little time consider booking a bus which can get you there in 5h 25m. The ticket price range depends on the travel mode: a train costs an average of $156, and a bus costs an average of $208.
Distance: 156 miles (252 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$208 Average price | $156 Average price Cheapest | $37 Average price (fuel + tolls) |
5h 55m Average total duration Fastest 5h 25m Onboard + 30m Additional time* | 10h 10m Average total duration 9h 40m Onboard + 30m Additional time* | 2h 40m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence, SC to Greenville, SC is a train with an average price of $156 (€128).
This is compared to other travel options from Florence, SC to Greenville, SC:
A train is $51 (€42) less than a bus for this route with tickets for a bus from Florence, SC to Greenville, SC costing on average $208 (€170).
The fastest way to travel from Florence, SC to Greenville, SC is by bus with an average journey time of 5h 25m.
Other travel options to Greenville, SC take longer:
Train takes on average 9h 40m.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Greenville, SC including taking a bus and train.
We recommend using the train as it is the most popular way to get from Florence, SC to Greenville, SC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Florence, SC to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:00PM | Arrival Time 11:25PM | Duration 5h25 | Departure days Mon | Cheapest price $208 |
Compare prices and tickets Florence, SC to Greenville, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Florence, SC to Greenville, SC
USAUSA
Buses from Florence, SC to Greenville, SC run on average 2 times per day, taking around 5h 25m. Cheap bus tickets for this journey start at $208 (€170) but you can travel from only $156 (€128) by train.
The earliest bus runs at 08:40, the last at 22:00. The fastest bus covers the 156 miles (252 km) distance in 5h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $156 (€128)
Distance 156 miles (252 km) |
Average bus duration 5h 25m |
Cheapest ticket price $208 (€170) |
Buses per day 2 |
Fastest bus 5h 25m |
First bus 8:40 AM |
Last bus 10:00 PM |
Cheapest Month Jul |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $156 (€128)
Complete guide to Greenville
Things to do in Greenville
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
- Recommended
Upcountry History Museum
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
- Recommended
Sigal Music Museum
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
- Must visit
Main Street
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
- Must visit
Falls Park on the Reedy
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
- Must visit
Swamp Rabbit Trail
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
- Gluten-free
South Carolina Barbecue
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
- Vegetarian
Fried Green Tomatoes
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
- Gluten-free
Shrimp And Grits
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
The Anchorage
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
Soby's
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Smoke On The Water
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
United States Dollar
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual restaurant.
- Fine dining
- USD 50-100+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a coffee drink.
Tipping culture
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
FAQs: Bus from Florence, SC to Greenville, SC
Find answers to the most common questions about traveling from Florence, SC to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Florence, SC to Greenville, SC can start from as little as $208 (€170) when you book in advance. The average bus ticket price for Florence, SC to Greenville, SC is $208 (€170) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Greenville, SC is 5h 25m to travel the 156 miles (252 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Greenville, SC leaves at 8:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Greenville, SC leaves at 10:00 PM.
A trip to Greenville, SC from Florence, SC is worth doing but not as a day trip with a journey time of 5h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Greenville, SC is July.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Greenville, SC including taking a bus and train.
No, the bus from Florence, SC to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Florence, SC to Greenville, SC.
No, bikes are not allowed on board the bus from Florence, SC to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Florence, SC to Greenville, SC.
No, luggage for the bus from Florence, SC to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Florence, SC to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Florence, SC to Greenville, SC.
No, there are no USB plugs on board the bus from Florence, SC to Greenville, SC.
No, there is no WiFi on board the bus from Florence, SC to Greenville, SC.
Since neither Florence, SC nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Florence, SC to Greenville, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Florence, SC to Greenville, SC
Florence
Greenville
The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Greenville.
Florence, S Irby St (Greyhound Bus Stop)
information
The major bus station for arrivals in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip to Greenville from Florence.
Greenville, Woodruff Rd ("Raceway" gas station)
information
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Florence, SC
Most popular bus connections to Greenville, SC
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