- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
The best way to find a cheap bus ticket from Washington, DC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Washington, DC to Greenville, SC will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $71.
On Tue, Nov 03, we found 5 buses from Washington, DC to Greenville, SC, including 3 direct services.
On Tue, Nov 03 the direct buses cover the 655 km distance in an average of 12 h 5 m but if you time it right, some buses will get you there in just 10 h 35 m .
On Tue, Nov 03 the slowest buses will take 13 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Washington, DC to Greenville, SC run on average 6 times per day, taking around 10h 46m. Cheap bus tickets for this journey start at $58 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:30, the last at 22:45. The fastest bus covers the 406 miles (655 km) distance in 9h 20m.
Distance 406 miles (655 km) |
Average bus duration 10h 46m |
Cheapest ticket price $58 |
Buses per day 6 |
Direct buses 5 |
Fastest bus 9h 20m |
First bus 12:30 AM |
Last bus 10:45 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 28 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Washington, DC to Greenville, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:10AM | Arrival Time 02:50PM | Duration 12h40 | Departure days Fri, Sat | Cheapest price $154 |
Operator FlixBus | Departure Time 02:40AM | Arrival Time 01:15PM | Duration 10h35 | Departure days Tue, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 02:45AM | Arrival Time 12:35PM | Duration 9h50 | Departure days Tue, Thu, Fri, Sat | Cheapest price $77 |
Operator Greyhound | Departure Time 03:10AM | Arrival Time 03:50PM | Duration 12h40 | Departure days Tue, Fri | Cheapest price $85 |
Operator FlixBus | Departure Time 03:45AM | Arrival Time 01:35PM | Duration 9h50 | Departure days Thu, Fri, Sat | Cheapest price $66 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 02:35PM | Duration 10h45 | Departure days Tue, Sat, Sun | Cheapest price $71 |
Operator Greyhound | Departure Time 07:15AM | Arrival Time 08:10PM | Duration 12h55 | Departure days Tue | Cheapest price $78 |
Operator Greyhound | Departure Time 07:40AM | Arrival Time 06:35PM | Duration 10h55 | Departure days Thu | Cheapest price $77 |
Operator FlixBus | Departure Time 09:05AM | Arrival Time 07:35PM | Duration 10h30 | Departure days Sat, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 01:15PM | Arrival Time 11:25PM | Duration 10h10 | Departure days Mon | Cheapest price $65 |
Operator Greyhound | Departure Time 10:10PM | Arrival Time 10:50AM | Duration 12h40 | Departure days Tue, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 08:40AM | Duration 9h55 | Departure days Sat, Sun | Cheapest price $77 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 01:15PM | Duration 13h30 | Departure days Tue, Sat, Sun | Cheapest price $78 |
The table below shows live departures for Washington, DC to Greenville, SC buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 2:40 AM Washington, Columbus Circle, Union Station | 10h35 | 1:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 0 transfersDirect | |
![]() | 3:50 AM Washington, Columbus Circle, Union Station | 10h45 | 2:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 0 transfersDirect | |
· | 7:15 AM Washington, Columbus Circle, Union Station | 12h55 | 8:10 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
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Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
South Carolina barbecue is slow-smoked pork, often chopped or pulled, and classically served with the state’s distinctive mustard-based sauce.
Shrimp and grits pairs creamy stone-ground grits with shrimp, often enriched with bacon or sausage. It is a Lowcountry staple found across Greenville.
Fried green tomatoes are tart unripe tomatoes breaded and fried. They are a beloved Southern side and common on Upstate menus.
Casual Greenville barbecue spot serving smoked meats, classic sides, and a relaxed neighborhood atmosphere.
Upscale downtown steakhouse and oyster bar with dry-aged beef, seafood, and an elegant supper-club feel.
Refined Southern restaurant known for seasonal plates, thoughtful cocktails, and a polished downtown setting.
Moderate for a U.S. city. Hotels and dining are usually cheaper than major metros, but car travel and limited transit can add to visitor costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually get 10-15%. Cafes often have tip jars; $1-2 is common for drinks.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Greenville, SC.
Find answers to the most common questions about traveling from Washington, DC to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

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