- Must visit
The National WWII Museum
A major campus of immersive exhibits on World War II, widely regarded as one of the top museums in the United States.
Cheapest price
$215
Average price
$215
Fastest journey
18 h 35 m
Average duration
18 h 35 m
Buses per day
1
Distance
1079 km
The best way to find a cheap bus ticket from Florence, SC to New Orleans, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to New Orleans, LA will cost around $215 if you buy it on the day, but the cheapest tickets can be found for only $215.
Of the 1 buses that leave Florence, SC for New Orleans, LA on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 1079 km distance in an average of 18 h 35 m but if you time it right, some buses will get you there in just 18 h 35 m .
On Sat, Jun 20 the slowest buses will take 18 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Florence, SC to New Orleans, LA among Omio's users. If you are prioritising price take the bus with prices starting from $158. For those with little time consider booking a bus which can get you there in 20h 0m. The ticket price range depends on the travel mode: a bus costs an average of $158, and a train costs an average of $217.
Distance: 670 miles (1079 km)
Most popular Bus | Train | Driving |
|---|---|---|
$210 Average price Cheapest | $309 Average price | $153 Average price (fuel + tolls) |
20h 30m Average total duration Fastest 20h 0m Onboard + 30m Additional time* | 35h 48m Average total duration 35h 18m Onboard + 30m Additional time* | 10h 34m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to New Orleans, LA:
A bus is $98 (€80) less than a train for this route with tickets for a train from Florence, SC to New Orleans, LA costing on average $309 (€253).
Other travel options to New Orleans, LA take longer:
Train takes on average 35h 18m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 11:55AM | Arrival Time 05:30AM | Duration 17h35 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $220 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 10:30AM | Duration 18h35 | Departure days Sat | Cheapest price $215 |
Operator Flixbus USA | Departure Time 04:00PM | Arrival Time 04:55PM | Duration 24h55 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $219 |
Operator Greyhound USA | Departure Time 04:10PM | Arrival Time 08:35AM | Duration 16h25 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $220 |
Operator Greyhound | Departure Time 04:55PM | Arrival Time 11:30AM | Duration 18h35 | Departure days Thu | Cheapest price $239 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 01:35PM | Duration 17h25 | Departure days Thu | Cheapest price $229 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 09:55PM | Duration 25h25 | Departure days Thu | Cheapest price $158 |
The table below shows live departures for Florence, SC to New Orleans, LA buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:55 PM Florence, SC | 18h35 | 10:30 AM New Orleans, LA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence, SC to New Orleans, LA run on average 5 times per day, taking around 20h 0m. Cheap bus tickets for this journey start at $158 (€130) if you book in advance.
The earliest bus runs at 05:35, the last at 21:10. The fastest bus covers the 670 miles (1079 km) distance in 17h 25m.
Distance 670 miles (1079 km) |
Average bus duration 20h 0m |
Cheapest ticket price $158 (€130) |
Buses per day 5 |
Fastest bus 17h 25m |
First bus 5:35 AM |
Last bus 9:10 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of New Orleans — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect New Orleans trip today.
A major campus of immersive exhibits on World War II, widely regarded as one of the top museums in the United States.
The city’s leading fine arts museum, known for its broad collection and its sculpture garden in City Park.
A respected museum focused on Southern art, with strong permanent collections and rotating exhibitions.
The city’s signature historic neighborhood, known for balconies, music, architecture, and its dense concentration of sights.
The most famous street in New Orleans, known for nightlife, music, and nonstop energy in the French Quarter.
A picturesque neighborhood of oak-lined streets and grand historic mansions, popular for walking and architecture.
A Rich Louisiana stew often made with a dark roux, the holy trinity of vegetables, and seafood or sausage. It is one of the city’s signature Creole and Cajun dishes.
A Spiced rice dish cooked with meat or seafood, aromatics, and stock. It is a classic New Orleans favorite influenced by Spanish and French cooking traditions.
A Traditional sandwich on French bread, usually filled with fried shrimp, oysters, or roast beef with gravy. It is one of the city’s most iconic everyday meals.
An Iconic Garden District restaurant serving refined Creole cuisine in an elegant historic setting. Known for jazz brunch and polished service.
A Legendary Treme institution famous for Creole soul food, gumbo, and local history. The atmosphere is classic, welcoming, and deeply tied to the city’s culture.
A Popular Warehouse District restaurant focused on Cajun-inspired cooking, Louisiana meats, and bold regional flavors in a stylish rustic room.
Moderate for U.S. city travel. Food and drinks range widely, while hotels rise sharply during festivals and weekends.
Tip 18-20% at restaurants; 20%+ for great service. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Tip musicians only if invited or a tip jar is out.
Official public transport app
Louis Armstrong New Orleans International Airport, New Orleans -> Canal Street, New Orleans
Find answers to the most common questions about traveling from Florence, SC to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.

Most Florence, SC to New Orleans, LA buses use the Florence, S Irby St (Greyhound Bus Stop) to New Orleans, LA station pair, with some services arriving at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr). Use this guide to compare Florence, SC and New Orleans, LA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need