- Must visit
New Orleans Museum of Art
Leading art museum in City Park with major European, American, African, and contemporary collections plus a renowned sculpture garden.
Cheapest price on Sep 19
$100
Average ticket price on Sep 19
$100
Fastest journey on Sep 19
1 d 45 m
Average journey duration on Sep 19
1 d 5 h 58 m
Buses on Sep 19
2
Distance
1079 km
The best way to find a cheap bus ticket from Florence, SC to New Orleans, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to New Orleans, LA will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $100.
It's difficult to get from Florence, SC to New Orleans, LA without transferring at least 2 times.
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· · Omio recommends booking the bus as it is the most popular option from Florence, SC to New Orleans, LA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $157 For those with little time, consider booking a bus, which has an average total journey time of 22h 8m. Average ticket prices depend on the travel mode: a bus costs an average of $157, while a train costs an average of $531.
Distance: 670 miles (1079 km)
Most popular Bus | Train | Driving |
|---|---|---|
$157 Average price Cheapest | $531 Average price | $155 Average price (fuel + tolls) |
22h 8m Average total duration Fastest 21h 38m Onboard + 30m Additional time* | 34h 4m Average total duration 33h 34m Onboard + 30m Additional time* | 10h 34m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to New Orleans, LA:
A bus is $374 less than a train for this route with tickets for a train from Florence, SC to New Orleans, LA costing on average $531.
Other travel options to New Orleans, LA take longer:
Train takes on average 33h 34m.
Tickets start at around $157 compared to roughly $155 in fuel and tolls — a saving of about $-2.10. The journey takes 21h 38m versus 10h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:45AM | Arrival Time 05:30AM | Duration 24h45 | Departure days Sat | Cheapest price $100 |
Operator Greyhound USA | Departure Time 11:55AM | Arrival Time 05:30AM | Duration 17h35 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $220 |
Operator Flixbus USA | Departure Time 04:00PM | Arrival Time 04:55PM | Duration 24h55 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $219 |
Operator Greyhound USA | Departure Time 04:10PM | Arrival Time 08:35AM | Duration 16h25 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $220 |
Operator Greyhound | Departure Time 04:55PM | Arrival Time 11:30AM | Duration 18h35 | Departure days Thu | Cheapest price $240 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 01:35PM | Duration 17h25 | Departure days Thu | Cheapest price $230 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 09:55PM | Duration 25h25 | Departure days Thu | Cheapest price $158 |
The table below shows live departures for Florence, SC to New Orleans, LA buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:55 AM Florence, SC | 17h35 | 5:30 AM New Orleans, LA | 1 transfer | |
![]() | 4:00 PM Florence, SC | 24h55 | 4:55 PM New Orleans, LA | 2 transfers | |
![]() | 4:10 PM Florence, SC | 16h25 | 8:35 AM New Orleans, LA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence, SC to New Orleans, LA run on average 2 times per day, taking around 21h 38m. Cheap bus tickets for this journey start at $105 if you book in advance.
The earliest bus runs at 05:35, the last at 21:10. The fastest bus covers the 670 miles (1079 km) distance in 15h 55m.
Distance 670 miles (1079 km) |
Average bus duration 21h 38m |
Cheapest ticket price $105 |
Buses per day 2 |
Fastest bus 15h 55m |
First bus 5:35 AM |
Last bus 9:10 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of New Orleans, LA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect New Orleans, LA trip today.
Leading art museum in City Park with major European, American, African, and contemporary collections plus a renowned sculpture garden.
Powerful museum using immersive exhibits to explain World War II through personal stories, artifacts, and major military history.
Smithsonian-affiliated museum devoted to Southern art, design, and culture in a contemporary warehouse district setting.
The city’s most famous neighborhood, packed with historic architecture, music, courtyards, and essential New Orleans street life.
Lively public square facing St. Louis Cathedral, ideal for architecture, performers, and a classic introduction to the city.
Vast urban park with oak groves, lagoons, museums, and trails, offering one of the best green escapes in New Orleans.
A hearty Creole rice dish with sausage, chicken, and seafood. It reflects Spanish, French, and local influences central to New Orleans cooking.
A rich Louisiana stew usually made with roux, okra or filé, and seafood or sausage. It is a signature dish of Creole and Cajun tradition.
A classic po' boy is a French bread sandwich stuffed with fried shrimp, oysters, or roast beef. It is one of the city's most iconic everyday foods.
Celebrated Creole restaurant famous for gumbo z'herbes, turtle soup, and jazz brunch in an elegant Garden District mansion.
Casual landmark for classic po' boys and fried seafood. Expect a lively, old-school New Orleans atmosphere near the French Quarter.
Historic coffee stand best known for beignets and chicory café au lait. It is busy, informal, and one of the city's essential stops.
Moderate for U.S. cities: hotels can be pricey in peak season, but food and transit are reasonable for tourists.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or $1 at cafes for good service.
Official public transport app
Louis Armstrong New Orleans International Airport -> Canal Street, New Orleans, LA
Find answers to the most common questions about traveling from Florence, SC to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.

Most Florence, SC to New Orleans, LA buses use the Florence, W Lucas St (TA Gas Station) to New Orleans, LA station pair, with some services arriving at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr). Use this guide to compare Florence, SC and New Orleans, LA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food and snacks available at the gas station.
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
New Orleans, LA is 1 km from New Orleans city centre. Public transport options include:
New Orleans, LA has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at New Orleans, LA. ATMs are available at New Orleans, LA.
Ticket office support is available at New Orleans, LA.
Available at New Orleans, LA: Parking, Taxis, WC.
Accessibility facilities are available at New Orleans, LA: Station is wheelchair accessible.
Kenner, Louis Armstrong New Orleans International Airport (Airline Dr) is 1 km from New Orleans city centre. Public transport options include:
Kenner, Louis Armstrong New Orleans International Airport (Airline Dr) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets nearby.
Wi-Fi is available at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr). ATMs are available at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr).
Ticket office support is available at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr).
Available at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr): Parking, Taxis, WC.
Accessibility facilities are available at Kenner, Louis Armstrong New Orleans International Airport (Airline Dr): Wheelchair accessible entrance and facilities.
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