The cheapest and fastest buses from Tampa, FL to Greenville, SC
Cheapest price
€78
Average price
€82
Fastest journey
15 h 10 m
Average duration
17 h 50 m
Buses per day
6
Distance
768 km
The best way to find a cheap bus ticket from Tampa, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to Greenville, SC will cost around €82 if you buy it on the day, but the cheapest tickets can be found for only €78.
It's difficult to get from Tampa, FL to Greenville, SC without transferring at least 2 times.
FlixBus · FlixBus · FlixBus6:20 AM15h10Tampa, Marion Transit Center9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC€781One-way2 transfers
FlixBus · FlixBus+
5:25 PM17h15Tampa, USF Holly Drive (Central Plant), FL10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC€801One-way2 transfers
FlixBus · FlixBus+
4:55 PM17h45Tampa, Marion Transit Center10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC€811One-way2 transfers
+
FlixBus+
11:10 AM16h05Tampa, Marion Transit Center3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC€811One-way2 transfers
FlixBus+
+
FlixBus10:25 PM23h05Tampa, USF Holly Drive (Central Plant), FL9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC€861One-way2 transfers
FlixBus · FlixBus · FlixBus6:20 AM15h10Tampa, Marion Transit Center9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC€781One-way2 transfers
+
FlixBus+
11:10 AM16h05Tampa, Marion Transit Center3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC€811One-way2 transfers
FlixBus · FlixBus+
5:25 PM17h15Tampa, USF Holly Drive (Central Plant), FL10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC€801One-way2 transfers
FlixBus · FlixBus+
4:55 PM17h45Tampa, Marion Transit Center10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC€811One-way2 transfers
FlixBus+
+
FlixBus10:35 PM22h55Tampa, Marion Transit Center9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC€861One-way2 transfers
Travel Information
Compare bus, train, and flight for Tampa, FL to Greenville, SC
Omio recommends booking the train as it is the most popular option from Tampa, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €106. For those with little time consider booking a flight which can get you there in 1h 29m. The ticket price range depends on the travel mode: a bus costs an average of €106, and a train costs an average of €173.
Distance: 477 miles (768 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€136 Average price Cheapest | €226 Average price | €175 Average price | €93 Average price (fuel + tolls) |
18h 37m Average total duration 18h 7m Onboard + 30m Additional time* | 23h 54m Average total duration 23h 24m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 8h 35m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tampa, FL to Greenville, SC:
A bus is €39 less than a flight for this route with tickets for a flight from Tampa, FL to Greenville, SC costing on average €175.
A bus is €90 less than a train for this route with tickets for a train from Tampa, FL to Greenville, SC costing on average €226.
Other travel options to Greenville, SC take longer:
Bus takes on average 18h 7m.
Train takes on average 23h 24m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Tampa, FL to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:20AM | Arrival Time 09:30PM | Duration 15h10 | Departure days Everyday | Cheapest price €71 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 03:15AM | Duration 16h05 | Departure days Everyday | Cheapest price €70 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 10:40AM | Duration 17h45 | Departure days Everyday | Cheapest price €71 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 10:40AM | Duration 17h15 | Departure days Everyday | Cheapest price €71 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 09:30PM | Duration 23h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price €80 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 09:30PM | Duration 22h55 | Departure days Everyday | Cheapest price €80 |
Live departures
Tampa, FL to Greenville, SC bus times
The table below shows live departures for Tampa, FL to Greenville, SC buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+![]() | 4:55 PM Tampa, Marion Transit Center | 17h45 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
FlixBus · FlixBus+![]() | 5:25 PM Tampa, USF Holly Drive (Central Plant), FL | 17h15 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
FlixBus+ + FlixBus | 10:35 PM Tampa, Marion Transit Center | 22h55 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
| Wednesday, August 5 | |||||
FlixBus · FlixBus · FlixBus | 6:20 AM Tampa, Marion Transit Center | 15h10 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
+ FlixBus+![]() | 11:10 AM Tampa, Marion Transit Center | 16h05 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Tampa, FL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 05
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Aug 11
Journey information
Overview: Bus from Tampa, FL to Greenville, SC
Buses from Tampa, FL to Greenville, SC run on average 6 times per day, taking around 18h 7m. Cheap bus tickets for this journey start at €106 but you can travel from only €88 by flight.
The earliest bus runs at 02:23, the last at 22:35. The fastest bus covers the 477 miles (768 km) distance in 13h 5m.
Distance 477 miles (768 km) |
Average bus duration 18h 7m |
Cheapest ticket price €106 |
Buses per day 6 |
Fastest bus 13h 5m |
First bus 2:23 AM |
Last bus 10:35 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 77 days |
FAQs: Bus from Tampa, FL to Greenville, SC
Find answers to the most common questions about traveling from Tampa, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Tampa, FL to Greenville, SC
Most Tampa, FL to Greenville, SC buses use the Tampa, Marion Transit Center to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Tampa, FL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Tampa, FL station do buses to Greenville, SC leave from?
Getting to Tampa, Marion Transit Center from Tampa city centre
Tampa, Marion Transit Center bus station facilities and services
Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.
Tickets and information
Ticket office support is available at Tampa, Marion Transit Center.
Parking, taxis and toilets
Available at Tampa, Marion Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.
Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre
Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:
Tampa, USF Holly Drive (Central Plant) bus station facilities and services
Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).
Tickets and information
Ticket office support is available at Tampa, USF Holly Drive (Central Plant).
Parking, taxis and toilets
Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.
Which Greenville, SC station do buses from Tampa, FL arrive at?
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Most popular bus connections from Tampa, FL
More options for your journey from Tampa, FL to Greenville, SC
Here are some other resources that might have the information you need
