Tampa, FL to Greenville, SC bus with FlixBus

Sat, Sep 19
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The cheapest and fastest buses from Tampa, FL to Greenville, SC

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

kr517

Average ticket price on Sep 19

kr612

Fastest journey on Sep 19

12 h 35 m

Average journey duration on Sep 19

14 h 3 m

Buses on Sep 19

8

Distance

768 km

Cheap tickets

The best way to find a cheap bus ticket from Tampa, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Tampa, FL to Greenville, SC will cost around kr612 if you buy it on the day, but the cheapest tickets can be found for only kr517.

Fast buses

It's difficult to get from Tampa, FL to Greenville, SC without transferring at least once.

  • FlixBusFlixBus+Greyhound
    9:35 PM13h05
    Tampa, Marion Transit Center
    10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC
    kr5171One-way
    1 transfer
  • FlixBusFlixBus+Greyhound
    10:05 PM12h35
    Tampa, USF Holly Drive (Central Plant), FL
    10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC
    kr5171One-way
    1 transfer
  • FlixBusFlixBus · FlixBus+Greyhound+FlixBusFlixBus
    10:25 PM21h10
    Tampa, USF Holly Drive (Central Plant), FL
    7:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    kr5211One-way
    3 transfers
  • FlixBusFlixBus · FlixBus+Greyhound+FlixBusFlixBus
    10:35 PM21h00
    Tampa, Marion Transit Center
    7:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    kr5211One-way
    3 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    6:20 AM15h10
    Tampa, Marion Transit Center
    9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    kr5211One-way
    2 transfers

Travel Information

Compare bus and train for Tampa, FL to Greenville, SC

Omio recommends booking the flight as it is the most popular option from Tampa, FL to Greenville, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of kr803 For those with little time, consider booking a flight, which has an average total journey time of 5h 26m. Average ticket prices depend on the travel mode: a bus costs an average of kr803, while a flight costs an average of kr3655.

Distance: 477 miles (768 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

kr803

Average price

Cheapest

kr3655

Average price

kr1475

Average price

kr754

Average price

(fuel + tolls)

14h 12m

Average total duration

13h 42m

Onboard

+

30m

Additional time*

5h 26m

Average total duration

Fastest

3h 26m

Onboard

+

2h 0m

Additional time*

23h 34m

Average total duration

23h 4m

Onboard

+

30m

Additional time*

8h 35m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

American Airlines

Most popular airline

Amtrak

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Tampa, FL to Greenville, SC is a bus with an average price of kr803.

This is compared to other travel options from Tampa, FL to Greenville, SC:

A bus is kr672 less than a train for this route with tickets for a train from Tampa, FL to Greenville, SC costing on average kr1475.

A bus is kr2852 less than a flight for this route with tickets for a flight from Tampa, FL to Greenville, SC costing on average kr3655.

The fastest way to travel from Tampa, FL to Greenville, SC is by flight with an average journey time of 3h 26m.

Other travel options to Greenville, SC take longer:

Bus takes on average 13h 42m.

Train takes on average 23h 4m.

It's helpful to compare your options as there are 2 ways to travel between Tampa, FL and Greenville, SC including taking a bus and train.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Greenville, SC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around kr803 compared to roughly kr754 in fuel and tolls — a saving of about kr-49.12. The journey takes 13h 42m versus 8h 35m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Tampa, FL to Greenville, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
06:20AM
Arrival Time
09:30PM
Duration
15h10
Departure days
Everyday
Cheapest price
kr505
Operator
Greyhound
Departure Time
11:10AM
Arrival Time
03:15AM
Duration
16h05
Departure days
Everyday
Cheapest price
kr501
Operator
FlixBus
Departure Time
04:00PM
Arrival Time
07:00AM
Duration
15h00
Departure days
Mon, Tue, Thu, Fri, Sat, Sun
Cheapest price
kr561
Operator
FlixBus
Departure Time
04:35PM
Arrival Time
07:00AM
Duration
14h25
Departure days
Mon, Tue, Thu, Fri, Sat, Sun
Cheapest price
kr553
Operator
FlixBus
Departure Time
04:55PM
Arrival Time
10:40AM
Duration
17h45
Departure days
Wed
Cheapest price
kr517
Operator
FlixBus
Departure Time
05:25PM
Arrival Time
10:40AM
Duration
17h15
Departure days
Wed
Cheapest price
kr505
Operator
FlixBus
Departure Time
09:35PM
Arrival Time
10:40AM
Duration
13h05
Departure days
Mon, Tue, Thu, Fri, Sat, Sun
Cheapest price
kr501
Operator
FlixBus
Departure Time
10:05PM
Arrival Time
10:40AM
Duration
12h35
Departure days
Mon, Tue, Thu, Fri, Sat, Sun
Cheapest price
kr509
Operator
Greyhound
Departure Time
10:25PM
Arrival Time
07:35PM
Duration
21h10
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
kr521
Operator
Greyhound
Departure Time
10:35PM
Arrival Time
07:35PM
Duration
21h00
Departure days
Everyday
Cheapest price
kr521

Live departures

Tampa, FL to Greenville, SC bus times

The table below shows live departures for Tampa, FL to Greenville, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus+Greyhound9:35 PM Tampa, Marion Transit Center
13h05
10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
FlixBusFlixBus+Greyhound10:05 PM Tampa, USF Holly Drive (Central Plant), FL
12h35
10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
FlixBusFlixBus+Greyhound+FlixBusFlixBus10:25 PM Tampa, USF Holly Drive (Central Plant), FL
23h05
9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers
FlixBusFlixBus+Greyhound+FlixBusFlixBus10:35 PM Tampa, Marion Transit Center
22h55
9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers
Saturday, September 19
FlixBusFlixBus · FlixBus · FlixBus6:20 AM Tampa, Marion Transit Center
15h10
9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers
Greyhound+FlixBusFlixBus+Greyhound11:10 AM Tampa, Marion Transit Center
16h05
3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers
FlixBusFlixBus · FlixBus+Greyhound4:00 PM Tampa, Marion Transit Center
15h00
7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers
FlixBusFlixBus · FlixBus+Greyhound4:35 PM Tampa, USF Holly Drive (Central Plant), FL
14h25
7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Tampa, FL to Greenville, SC by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Tampa, FL to Greenville, SC buses with Omio?

Greyhound as well as FlixBus offer buses services from Tampa, FL to Greenville, SC.
Omio is an official ticket reseller for all your travel options from Tampa, FL to Greenville, SC.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Tampa, FL to Greenville, SC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from Tampa, FL to Greenville, SC.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Tampa, FL to Greenville, SC.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Tampa, FL to Greenville, SC.

Journey information

Overview: Bus from Tampa, FL to Greenville, SC

USAUSA
USAUSA
Icon of bus

Buses from Tampa, FL to Greenville, SC run on average 6 times per day, taking around 13h 42m. Cheap bus tickets for this journey start at kr561 but you can travel from only kr347 by flight.

The earliest bus runs at 02:23, the last at 22:35. The fastest bus covers the 477 miles (768 km) distance in 10h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from kr347
Distance
477 miles (768 km)
Average bus duration
13h 42m
Cheapest ticket price
kr561
Buses per day
6
Fastest bus
10h 35m
First bus
2:23 AM
Last bus
10:35 PM
Cheapest Month
Jul
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Oct - Dec
Busiest Day
Sat
Least Busy Day
Sat
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from kr347

Bus providers: FlixBus, Greyhound from Tampa, FL to Greenville, SCYou can travel by bus between Tampa, FL to Greenville, SC with FlixBus, Greyhound for as low as kr347. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 35m
Cheapest FlixBus Price
kr565
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
11h 45m
Cheapest Greyhound Price
kr561
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Greenville, SC

Things to do in Greenville, SC

Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.

  • Recommended

Greenville County Museum of Art

A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.

Greenville Center for Creative Arts

A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.

Metropolitan Arts Council Gallery

A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.

FAQs: Bus from Tampa, FL to Greenville, SC

Find answers to the most common questions about traveling from Tampa, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Tampa, FL to Greenville, SC can start from as little as kr561 when you book in advance. The average bus ticket price for Tampa, FL to Greenville, SC is kr803 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tampa, FL to Greenville, SC is 10h 35m to travel the 477 miles (768 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tampa, FL to Greenville, SC leaves at 2:23 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tampa, FL to Greenville, SC leaves at 10:35 PM.
There are 6 buses a day from Tampa, FL to Greenville, SC which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Tampa, FL to Greenville, SC, you can count on Greyhound, FlixBus for the best way to get you to Greenville, SC. You can also check all possible bus companies who offer a service between Tampa, FL and Greenville, SC and compare the amenities they offer before buying a bus ticket.
When departing from Tampa, FL , you have various bus station options to start your journey from including Tampa, Marion Transit Center, Tampa, USF Holly Drive (Central Plant), FL, Saint Petersburg, Central Avenue N / Dr Martin Luther King St Jr, FL, Pinellas Park, Shoppes at Park Place - Shelter - D . When arriving in Greenville, SC , you can end your journey in bus stations like Greenville, Woodruff Rd ("Raceway" gas station), SC .Passengers board the bus most frequently from Tampa, Marion Transit Center, which is located around away from the city centre, and they get off the bus at Greenville, Woodruff Rd ("Raceway" gas station), SC, located 8 away from the city centre.
A trip to Greenville, SC from Tampa, FL is worth doing but not as a day trip with a journey time of 10h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tampa, FL to Greenville, SC is July.
It's helpful to compare your options as there are 2 ways to travel between Tampa, FL and Greenville, SC including taking a bus and train.
Yes, there are bathrooms on board the bus from Tampa, FL to Greenville, SC for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from Tampa, FL to Greenville, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Tampa, FL to Greenville, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Tampa, FL to Greenville, SC.
Yes, the following luggage options are included when booking a bus ticket from Tampa, FL to Greenville, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Tampa, FL to Greenville, SC:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Tampa, FL to Greenville, SC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Tampa, FL to Greenville, SC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Tampa, FL to Greenville, SC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Tampa, FL to Greenville, SC with the following bus company: Greyhound, FlixBus.
Since neither Tampa, FL nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Greenville, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Tampa, FL to Greenville, SC

Most Tampa, FL to Greenville, SC buses use the Tampa, Marion Transit Center to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Tampa, FL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Tampa
Arrival bus stations in Greenville

Which Tampa, FL station do buses to Greenville, SC leave from?

Buses from Tampa, FL to Greenville, SC leave from Tampa, Marion Transit Center. The station is 0 miles (1 km) from Tampa, FL city centre at Marion Transit Center, 1211 N Marion St, Tampa, FL 33602, USA.
Tampa, Marion Transit CenterMarion Transit Center, 1211 N Marion St, Tampa, FL 33602, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Tampa, Marion Transit Center from Tampa city centre

Bus1, 5, 19, 30 · 3m · kr32 · every ~15 min

Tampa, Marion Transit Center bus station facilities and services

Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.

Tickets and information

Ticket office support is available at Tampa, Marion Transit Center.

Parking, taxis and toilets

Available at Tampa, Marion Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.

Tampa, USF Holly Drive (Central Plant)University of South Florida, Central Plant, 13302 USF Chestnut Dr, Tampa, FL 33620, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre

Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:

BusFlixBus 2421 · 26m · kr8
9, 400 · 1h 3m · kr32 · every ~7 min
6 · 1h 9m · kr32 · every ~5 min

Tampa, USF Holly Drive (Central Plant) bus station facilities and services

Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).

Tickets and information

Ticket office support is available at Tampa, USF Holly Drive (Central Plant).

Parking, taxis and toilets

Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.

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