- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
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The cheapest and fastest buses from Tampa, FL to Greenville, SC
Showing times and prices for Jun 21
Cheapest price
$123
Average price
$132
Fastest journey
15 h 10 m
Average duration
17 h 25 m
Buses per day
6
Distance
768 km
Cheap tickets
The best way to find a cheap bus ticket from Tampa, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to Greenville, SC will cost around $132 if you buy it on the day, but the cheapest tickets can be found for only $123.
Fast buses
It's difficult to get from Tampa, FL to Greenville, SC without transferring at least 2 times.
FlixBus · FlixBus · FlixBus · FlixBus10:35 PM20h50Tampa, Marion Transit Center7:25 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way3 transfers- FlixBus · FlixBus · FlixBus · FlixBus10:25 PM21h00Tampa, USF Holly Drive (Central Plant), FL7:25 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way3 transfers
- FlixBus · FlixBus · FlixBus6:20 AM15h10Tampa, Marion Transit Center9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way2 transfers
+FlixBus+11:10 AM16h05Tampa, Marion Transit Center3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1311One-way2 transfers- FlixBus · FlixBus+5:25 PM17h15Tampa, USF Holly Drive (Central Plant), FL10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1451One-way2 transfers
- FlixBus · FlixBus · FlixBus6:20 AM15h10Tampa, Marion Transit Center9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way2 transfers
- +FlixBus+11:10 AM16h05Tampa, Marion Transit Center3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1311One-way2 transfers
- FlixBus · FlixBus+5:25 PM17h15Tampa, USF Holly Drive (Central Plant), FL10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1451One-way2 transfers
- FlixBus · FlixBus+4:55 PM17h45Tampa, Marion Transit Center10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1481One-way2 transfers
- FlixBus · FlixBus · FlixBus · FlixBus10:35 PM20h50Tampa, Marion Transit Center7:25 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way3 transfers
Travel Information
Compare bus, train, and flight for Tampa, FL to Greenville, SC
Omio recommends booking the train as it is the most popular option from Tampa, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $129. For those with little time consider booking a flight which can get you there in 1h 29m. The ticket price range depends on the travel mode: a bus costs an average of $129, and a train costs an average of $211.
Distance: 477 miles (768 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$167 Average price Cheapest | $277 Average price | $214 Average price | $114 Average price (fuel + tolls) |
18h 37m Average total duration 18h 7m Onboard + 30m Additional time* | 23h 54m Average total duration 23h 24m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 8h 35m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Tampa, FL to Greenville, SC is a bus with an average price of $167 (€136).
This is compared to other travel options from Tampa, FL to Greenville, SC:
A bus is $47 (€39) less than a flight for this route with tickets for a flight from Tampa, FL to Greenville, SC costing on average $214 (€175).
A bus is $110 (€90) less than a train for this route with tickets for a train from Tampa, FL to Greenville, SC costing on average $277 (€226).
The fastest way to travel from Tampa, FL to Greenville, SC is by flight with an average journey time of 1h 29m.
Other travel options to Greenville, SC take longer:
Bus takes on average 18h 7m.
Train takes on average 23h 24m.
It's helpful to compare your options as there are 3 ways to travel between Tampa, FL and Greenville, SC including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Tampa, FL to Greenville, SC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Tampa, FL to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:20AM | Arrival Time 09:30PM | Duration 15h10 | Departure days Everyday | Cheapest price $109 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 03:15AM | Duration 16h05 | Departure days Everyday | Cheapest price $112 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 10:40AM | Duration 17h45 | Departure days Everyday | Cheapest price $98 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 10:40AM | Duration 17h15 | Departure days Everyday | Cheapest price $99 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 07:25PM | Duration 21h00 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $101 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 09:30PM | Duration 23h05 | Departure days Mon | Cheapest price $134 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 07:25PM | Duration 20h50 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $101 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 09:30PM | Duration 22h55 | Departure days Mon, Tue | Cheapest price $134 |
Live departures
Tampa, FL to Greenville, SC bus times
The table below shows live departures for Tampa, FL to Greenville, SC buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus+ | 4:55 PM Tampa, Marion Transit Center | 17h45 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
| FlixBus · FlixBus+ | 5:25 PM Tampa, USF Holly Drive (Central Plant), FL | 17h15 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 10:25 PM Tampa, USF Holly Drive (Central Plant), FL | 21h00 | 7:25 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 10:35 PM Tampa, Marion Transit Center | 20h50 | 7:25 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
| Sunday, June 21 | |||||
| FlixBus · FlixBus · FlixBus | 6:20 AM Tampa, Marion Transit Center | 15h10 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
| +FlixBus+ | 11:10 AM Tampa, Marion Transit Center | 16h05 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Tampa, FL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Tampa, FL to Greenville, SC
USAUSA
Buses from Tampa, FL to Greenville, SC run on average 6 times per day, taking around 18h 7m. Cheap bus tickets for this journey start at $129 (€106) but you can travel from only $107 (€88) by flight.
The earliest bus runs at 02:23, the last at 22:35. The fastest bus covers the 477 miles (768 km) distance in 13h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $107 (€88)
Distance 477 miles (768 km) |
Average bus duration 18h 7m |
Cheapest ticket price $129 (€106) |
Buses per day 6 |
Fastest bus 13h 5m |
First bus 2:23 AM |
Last bus 10:35 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 77 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $107 (€88)
Complete guide to Greenville
Things to do in Greenville
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
- Recommended
Upcountry History Museum
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
- Recommended
Sigal Music Museum
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
- Must visit
Main Street
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
- Must visit
Falls Park on the Reedy
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
- Must visit
Swamp Rabbit Trail
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
- Gluten-free
South Carolina Barbecue
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
- Vegetarian
Fried Green Tomatoes
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
- Gluten-free
Shrimp And Grits
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
The Anchorage
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
Soby's
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Smoke On The Water
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
United States Dollar
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual restaurant.
- Fine dining
- USD 50-100+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a coffee drink.
Tipping culture
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
FAQs: Bus from Tampa, FL to Greenville, SC
Find answers to the most common questions about traveling from Tampa, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Tampa, FL to Greenville, SC can start from as little as $129 (€106) when you book in advance. The average bus ticket price for Tampa, FL to Greenville, SC is $167 (€136) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tampa, FL to Greenville, SC is 13h 5m to travel the 477 miles (768 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tampa, FL to Greenville, SC leaves at 2:23 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tampa, FL to Greenville, SC leaves at 10:35 PM.
A trip to Greenville, SC from Tampa, FL is worth doing but not as a day trip with a journey time of 13h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tampa, FL to Greenville, SC is July.
It's helpful to compare your options as there are 3 ways to travel between Tampa, FL and Greenville, SC including taking a bus, train, and flight.
No, the bus from Tampa, FL to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Tampa, FL to Greenville, SC.
No, bikes are not allowed on board the bus from Tampa, FL to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Tampa, FL to Greenville, SC.
No, luggage for the bus from Tampa, FL to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Tampa, FL to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Tampa, FL to Greenville, SC.
No, there are no USB plugs on board the bus from Tampa, FL to Greenville, SC.
No, there is no WiFi on board the bus from Tampa, FL to Greenville, SC.
Since neither Tampa, FL nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Tampa, FL to Greenville, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Tampa, FL to Greenville, SC
Tampa
Greenville
The major bus station for departures in Tampa is Tampa, Marion Transit Center. Find all the information you need to know about services, amenities and connections at Tampa, Marion Transit Center for your trip from Tampa to Greenville.
Tampa, Marion Transit Center
information
Tampa, USF Holly Drive (Central Plant)
information
The major bus station for arrivals in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip to Greenville from Tampa.
Greenville, Woodruff Rd ("Raceway" gas station)
information
Most popular bus connections from Tampa, FL
More options for your journey from Tampa, FL to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Tampa, FL
Most popular bus connections to Greenville, SC
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