- Must visit
International African American Museum
Powerful museum at Gadsden’s Wharf interpreting the African American journey in Charleston through immersive, thoughtfully curated exhibits.
The best way to find a cheap bus ticket from Florence, SC to Charleston, WV is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Charleston, WV will cost around $85 if you buy it on the day, but the cheapest tickets can be found for only $85.
It's difficult to get from Florence, SC to Charleston, WV without transferring at least once.

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Take a bus from Florence, SC to Charleston, WV and enjoy the approximately 305 miles (491 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 05:20, the last at 16:15.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Florence, SC to Charleston, WV.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 02:00PM | Arrival Time 11:20PM | Duration 9h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $85 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 12:20PM | Duration 15h50 | Departure days Thu | Cheapest price $175 |
The table below shows live departures for Florence, SC to Charleston, WV buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:00 PM Florence, SC | 9h20 | 11:20 PM Charleston, WV | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Florence, SC to Charleston, WV with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Charleston, WV — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, WV trip today.
Powerful museum at Gadsden’s Wharf interpreting the African American journey in Charleston through immersive, thoughtfully curated exhibits.
Small but engaging art museum known for Charleston Renaissance works, historic interiors, and a manageable visit in the French Quarter.
Leading museum on Charleston history in a landmark building, with strong exhibits on the city’s growth, culture, and difficult past.
Waterfront park with fountains, swings, harbor breezes, and broad views. A relaxing stop near the Historic District and cruise terminal.
Historic market district with open-air sheds, local crafts, and constant foot traffic. Useful for browsing and orienting yourself downtown.
Scenic promenade along the harbor lined with antebellum homes, gardens, and sea views. Ideal for a classic Charleston walking route.
A Lowcountry one-pot rice dish with shrimp or sausage, descended from West African rice cookery and long tied to Charleston home cooking.
Fresh local shrimp served over creamy grits, often enriched with butter, bacon, or gravy. It is a signature South Carolina coastal comfort dish.
A rich crab soup made with blue crab, roe, and cream or milk. It is a classic Charleston and Lowcountry specialty with deep local roots.
Long-running Southern restaurant known for shrimp and grits, she-crab soup, and polished service near the City Market.
Historic downtown oyster hall known for fresh local seafood, raw bar favorites, and a lively classic Charleston atmosphere.
Beloved seafood restaurant on Shem Creek serving Lowcountry classics, fried platters, and creek views in a casual setting.
Moderate for a US coastal city: hotels and historic-area dining cost more, but casual meals and local transit stay manageable for most visitors.
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. Cafes often have tip jars or screen prompts; $1-2 is common.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, WV.
Find answers to the most common questions about traveling from Florence, SC to Charleston, WV by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, WV, this guide helps you travel smarter and with confidence.

Most Florence, SC to Charleston, WV buses use the Florence, S Irby St (Greyhound Bus Stop) to Charleston, Greyhound Bus Station station pair. Use this guide to compare Florence, SC and Charleston, WV bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Charleston, Greyhound Bus Station is 1 km from Charleston city centre. Public transport options include:
Charleston, Greyhound Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi available in the waiting area. ATMs are available at Charleston, Greyhound Bus Station.
Ticket office support is available at Charleston, Greyhound Bus Station.
Available at Charleston, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Greyhound Bus Station: Wheelchair accessible entrances available.
Check bus stations information for Florence, SC and Charleston, WV, including where buses depart and arrive on this route.