- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
The best way to find a cheap bus ticket from Florence, SC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Charleston, SC will cost around $29 if you buy it on the day, but the cheapest tickets can be found for only $29.
On Tue, Nov 03, we found 2 buses from Florence, SC to Charleston, SC, including 2 direct services.
On Tue, Nov 03 the direct buses cover the 159 km distance in an average of 4 h 18 m but if you time it right, some buses will get you there in just 4 h 15 m .
On Tue, Nov 03 the slowest buses will take 4 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Florence, SC to Charleston, SC run on average 1 times per day, taking around 3h 56m. Cheap bus tickets for this journey start at $31 but you can travel from only $18 by train.
There are 1 buses per day. The earliest bus runs at 11:15, the last at 14:10. The fastest bus covers the 98 miles (159 km) distance in 3h 25m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Florence, SC to Charleston, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:50AM | Arrival Time 02:05PM | Duration 4h15 | Departure days Tue | Cheapest price $29 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 06:30PM | Duration 4h20 | Departure days Tue | Cheapest price $29 |
Operator Greyhound | Departure Time 06:10PM | Arrival Time 10:30PM | Duration 4h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $30 |
Operator Greyhound | Departure Time 07:10PM | Arrival Time 11:30PM | Duration 4h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $26 |
The table below shows live departures for Florence, SC to Charleston, SC buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:10 PM Florence, SC | 4h20 | 10:30 PM Charleston, SC | 0 transfersDirect | |
![]() | 7:10 PM Florence, SC | 4h20 | 11:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Florence, SC to Charleston, SC with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, SC.
Find answers to the most common questions about traveling from Florence, SC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Florence, SC to Charleston, SC buses use the Florence, S Irby St (Greyhound Bus Stop) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Florence, SC and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food and snacks available at the gas station.
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Check bus stations information for Florence, SC and Charleston, SC, including where buses depart and arrive on this route.