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Travel Information
Compare bus, train, and flight for Chicago, IL to Greenville, SC
Omio recommends booking the train as it is the most popular option from Chicago, IL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €120. For those with little time consider booking a flight which can get you there in 6h 35m. The ticket price range depends on the travel mode: a bus costs an average of €120, and a train costs an average of €430.
Distance: 561 miles (903 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€120 Average price Cheapest | €430 Average price | €399 Average price |
21h 10m Average total duration 20h 40m Onboard + 30m Additional time* | 28h 49m Average total duration 28h 19m Onboard + 30m Additional time* | 9h 35m Average total duration Fastest 6h 35m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Chicago, IL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Chicago, IL to Greenville, SC
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Buses from Chicago, IL to Greenville, SC run on average 6 times per day, taking around 20h 40m. Cheap bus tickets for this journey start at $148 (€120) if you book in advance.
The earliest bus runs at 08:40, the last at 22:30. The fastest bus covers the 561 miles (903 km) distance in 20h 40m.
Distance 561 miles (903 km) |
Average bus duration 20h 40m |
Cheapest ticket price $148 (€120) |
Buses per day 6 |
Fastest bus 20h 40m |
First bus 08:40 |
Last bus 22:30 |
FAQs: Bus from Chicago, IL to Greenville, SC
Find answers to the most common questions about traveling from Chicago, IL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
To find the cheapest bus tickets for your trip from Chicago, IL to Greenville, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Chicago, IL to Greenville, SC
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Greenville, SC
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Most popular buses to and from Greenville, SC and Chicago, IL
Most popular bus connections to Greenville, SC
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