4.9
4.6The cheapest and fastest buses from Chicago, IL to Greenville, SC
Cheapest price on Sep 17
kr629
Average ticket price on Sep 17
kr677
Fastest journey on Sep 17
19 h 45 m
Average journey duration on Sep 17
20 h 17 m
Buses on Sep 17
8
Distance
903 km
The best way to find a cheap bus ticket from Chicago, IL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Greenville, SC will cost around kr677 if you buy it on the day, but the cheapest tickets can be found for only kr629.
It's difficult to get from Chicago, IL to Greenville, SC without transferring at least once.
FlixBus · FlixBus · FlixBus5:05 PM22h05Chicago, Greyhound Bus Station4:10 PMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6291One-way2 transfers
+FlixBus2:45 PM20h50Chicago, Greyhound Bus Station12:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6291One-way1 transfer- FlixBus+1:00 PM20h40Chicago, Greyhound Bus Station10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6411One-way1 transfer
- · 9:55 AM20h05Chicago, Greyhound Bus Station7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6531One-way1 transfer
- · 10:15 AM19h45Chicago, Union Station (Amtrak), IL7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6531One-way1 transfer
- · 10:15 AM19h45Chicago, Union Station (Amtrak), IL7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6531One-way1 transfer
- · 9:55 AM20h05Chicago, Greyhound Bus Station7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6531One-way1 transfer
- · 6:10 AM20h05Chicago, Greyhound Bus Station3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6721One-way1 transfer
- FlixBus+1:00 PM20h40Chicago, Greyhound Bus Station10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6411One-way1 transfer
- +FlixBus2:45 PM20h50Chicago, Greyhound Bus Station12:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SCkr6291One-way1 transfer
Travel Information
Compare bus and train for Chicago, IL to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Chicago, IL to Greenville, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of kr886 For those with little time, consider booking a bus, which has an average total journey time of 18h 39m. Average ticket prices depend on the travel mode: a bus costs an average of kr886, while a train costs an average of kr3708.
Distance: 561 miles (903 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
kr886 Average price Cheapest | kr3708 Average price | kr893 Average price (fuel + tolls) |
18h 39m Average total duration Fastest 18h 9m Onboard + 30m Additional time* | 29h 4m Average total duration 28h 34m Onboard + 30m Additional time* | 10h 59m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Chicago, IL to Greenville, SC:
A bus is kr2703 less than a flight for this route with tickets for a flight from Chicago, IL to Greenville, SC costing on average kr3589.
A bus is kr2822 less than a train for this route with tickets for a train from Chicago, IL to Greenville, SC costing on average kr3708.
Other travel options to Greenville, SC take longer:
Bus takes on average 18h 9m.
Train takes on average 28h 34m.
Tickets start at around kr886 compared to roughly kr893 in fuel and tolls — a saving of about kr7. The journey takes 18h 9m versus 10h 59m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Chicago, IL to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:10AM | Arrival Time 03:15AM | Duration 20h05 | Departure days Everyday | Cheapest price kr557 |
Operator Greyhound | Departure Time 09:55AM | Arrival Time 07:00AM | Duration 20h05 | Departure days Everyday | Cheapest price kr593 |
Operator Greyhound | Departure Time 10:15AM | Arrival Time 07:00AM | Duration 19h45 | Departure days Everyday | Cheapest price kr593 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 10:40AM | Duration 20h40 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price kr585 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:35PM | Duration 20h50 | Departure days Thu | Cheapest price kr629 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 04:10PM | Duration 22h05 | Departure days Thu | Cheapest price kr629 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:35PM | Duration 17h35 | Departure days Wed, Fri, Sat, Sun | Cheapest price kr537 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 09:30PM | Duration 21h40 | Departure days Everyday | Cheapest price kr633 |
Operator Greyhound | Departure Time 11:10PM | Arrival Time 09:30PM | Duration 21h20 | Departure days Everyday | Cheapest price kr633 |
Live departures
Chicago, IL to Greenville, SC bus times
The table below shows live departures for Chicago, IL to Greenville, SC buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 6:00 PM Chicago, Greyhound Bus Station | 17h35 | 12:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| +FlixBus | 10:50 PM Chicago, Greyhound Bus Station | 21h40 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| +FlixBus | 11:10 PM Chicago, Union Station (Amtrak), IL | 21h20 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| Thursday, September 17 | |||||
| · | 6:10 AM Chicago, Greyhound Bus Station | 20h05 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| · | 9:55 AM Chicago, Greyhound Bus Station | 20h05 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| · | 10:15 AM Chicago, Union Station (Amtrak), IL | 19h45 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus+ | 1:00 PM Chicago, Greyhound Bus Station | 20h40 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| +FlixBus | 2:45 PM Chicago, Greyhound Bus Station | 20h50 | 12:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Greenville, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Why should you book Chicago, IL to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Chicago, IL to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Chicago, IL to Greenville, SC.
Journey information
Overview: Bus from Chicago, IL to Greenville, SC
USAUSA
Buses from Chicago, IL to Greenville, SC run on average 7 times per day, taking around 18h 9m. Cheap bus tickets for this journey start at kr577 if you book in advance.
The earliest bus runs at 00:30, the last at 23:50. The fastest bus covers the 561 miles (903 km) distance in 15h 0m.
Distance 561 miles (903 km) |
Average bus duration 18h 9m |
Cheapest ticket price kr577 |
Buses per day 7 |
Fastest bus 15h 0m |
First bus 12:30 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 28 days |
Bus providers: Greyhound, FlixBus from Chicago, IL to Greenville, SCYou can travel by bus between Chicago, IL to Greenville, SC with Greyhound, FlixBus for as low as kr577. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Chicago, IL to Greenville, SC
Find answers to the most common questions about traveling from Chicago, IL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Chicago, IL to Greenville, SC
Most Chicago, IL to Greenville, SC buses use the Chicago, Greyhound Bus Station to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Chicago, IL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Chicago, IL station do buses to Greenville, SC leave from?
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
Getting to Chicago, 95th Red Line Station from Chicago city centre
Chicago, 95th Red Line Station is 14 km from Chicago city centre. Public transport options include:
Chicago, 95th Red Line Station bus station facilities and services
Chicago, 95th Red Line Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Chicago, 95th Red Line Station. ATMs are available at Chicago, 95th Red Line Station.
Tickets and information
Ticket office support is available at Chicago, 95th Red Line Station.
Parking, taxis and toilets
Available at Chicago, 95th Red Line Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, 95th Red Line Station: Wheelchair accessible entrances available.
Which Greenville, SC station do buses from Chicago, IL arrive at?
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Chicago, IL
Most popular bus connections to Greenville, SC
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