4.9
4.6The cheapest and fastest buses from Chicago, IL to Greenville, SC
Cheapest price
CHF75
Average price
CHF84
Fastest journey
18 h 55 m
Average duration
20 h
Buses per day
7
Distance
903 km
The best way to find a cheap bus ticket from Chicago, IL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Greenville, SC will cost around CHF84 if you buy it on the day, but the cheapest tickets can be found for only CHF75.
It's difficult to get from Chicago, IL to Greenville, SC without transferring at least once.
FlixBus · FlixBus6:00 PM21h10Chicago, Greyhound Bus Station4:10 PMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF751One-way1 transfer
· 9:55 AM20h05Chicago, Greyhound Bus Station7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF781One-way1 transfer- · 10:15 AM19h45Chicago, Union Station (Amtrak), IL7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF781One-way1 transfer
- FlixBus+ · · 2:45 PM18h55Chicago, Greyhound Bus Station10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF801One-way3 transfers
- · 6:10 AM20h05Chicago, Greyhound Bus Station3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF831One-way1 transfer
- FlixBus+ · · 2:45 PM18h55Chicago, Greyhound Bus Station10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF801One-way3 transfers
- · 10:15 AM19h45Chicago, Union Station (Amtrak), IL7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF781One-way1 transfer
- · 6:10 AM20h05Chicago, Greyhound Bus Station3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF831One-way1 transfer
- · 9:55 AM20h05Chicago, Greyhound Bus Station7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF781One-way1 transfer
- FlixBus · FlixBus6:00 PM21h10Chicago, Greyhound Bus Station4:10 PMGreenville, Woodruff Rd ("Raceway" gas station), SCCHF751One-way1 transfer
Travel Information
Compare bus, train, and flight for Chicago, IL to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Chicago, IL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from CHF115. For those with little time consider booking a flight which can get you there in 1h 56m. The ticket price range depends on the travel mode: a bus costs an average of CHF115, and a flight costs an average of CHF308.
Distance: 561 miles (903 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
CHF115 Average price Cheapest | CHF195 Average price | CHF308 Average price | CHF110 Average price (fuel + tolls) |
17h 58m Average total duration 17h 28m Onboard + 30m Additional time* | 28h 49m Average total duration 28h 19m Onboard + 30m Additional time* | 4h 56m Average total duration Fastest 1h 56m Onboard + 3h 0m Additional time* | 10h 59m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Chicago, IL to Greenville, SC:
A bus is CHF81 less than a train for this route with tickets for a train from Chicago, IL to Greenville, SC costing on average CHF195.
A bus is CHF193 less than a flight for this route with tickets for a flight from Chicago, IL to Greenville, SC costing on average CHF308.
Other travel options to Greenville, SC take longer:
Bus takes on average 17h 28m.
Train takes on average 28h 19m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Chicago, IL to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:10AM | Arrival Time 03:15AM | Duration 20h05 | Departure days Everyday | Cheapest price CHF79 |
Operator Greyhound | Departure Time 09:55AM | Arrival Time 07:00AM | Duration 20h05 | Departure days Everyday | Cheapest price CHF76 |
Operator Greyhound | Departure Time 10:15AM | Arrival Time 07:00AM | Duration 19h45 | Departure days Everyday | Cheapest price CHF76 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 10:40AM | Duration 20h40 | Departure days Fri | Cheapest price CHF77 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:00PM | Duration 20h15 | Departure days Wed, Fri | Cheapest price CHF76 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 10:40AM | Duration 18h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price CHF79 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 04:10PM | Duration 21h55 | Departure days Thu | Cheapest price CHF83 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 04:10PM | Duration 21h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price CHF75 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 09:30PM | Duration 21h40 | Departure days Everyday | Cheapest price CHF86 |
Operator Greyhound | Departure Time 11:10PM | Arrival Time 09:30PM | Duration 21h20 | Departure days Everyday | Cheapest price CHF86 |
Live departures
Chicago, IL to Greenville, SC bus times
The table below shows live departures for Chicago, IL to Greenville, SC buses for today, Sunday, August 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · +FlixBus+ | 2:45 PM Chicago, Greyhound Bus Station | 18h55 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
| FlixBus · FlixBus | 6:00 PM Chicago, Greyhound Bus Station | 21h10 | 4:10 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| +FlixBus | 10:50 PM Chicago, Greyhound Bus Station | 21h40 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| +FlixBus | 11:10 PM Chicago, Union Station (Amtrak), IL | 21h20 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| Monday, August 3 | |||||
| · | 6:10 AM Chicago, Greyhound Bus Station | 20h05 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| · | 9:55 AM Chicago, Greyhound Bus Station | 20h05 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| · | 10:15 AM Chicago, Union Station (Amtrak), IL | 19h45 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Chicago, IL to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Chicago, IL to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Chicago, IL to Greenville, SC.
Journey information
Overview: Bus from Chicago, IL to Greenville, SC
USAUSA
Buses from Chicago, IL to Greenville, SC run on average 6 times per day, taking around 17h 28m. Cheap bus tickets for this journey start at CHF115 if you book in advance.
The earliest bus runs at 00:30, the last at 23:50. The fastest bus covers the 561 miles (903 km) distance in 20h 40m.
Distance 561 miles (903 km) |
Average bus duration 17h 28m |
Cheapest ticket price CHF115 |
Buses per day 6 |
Fastest bus 20h 40m |
First bus 12:30 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Best time to book 7 days |
Bus providers: FlixBus from Chicago, IL to Greenville, SCYou can travel by bus between Chicago, IL to Greenville, SC with FlixBus for as low as CHF115. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Chicago, IL to Greenville, SC
Find answers to the most common questions about traveling from Chicago, IL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Chicago, IL to Greenville, SC
Most Chicago, IL to Greenville, SC buses use the Chicago, Greyhound Bus Station to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Chicago, IL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Getting to Chicago, 95th Red Line Station from Chicago city centre
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Chicago, IL
Most popular bus connections to Greenville, SC
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