- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
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The cheapest and fastest buses from Orlando, FL to Greenville, SC
Showing times, prices and bookable tickets for Oct 21
Cheapest price on Oct 21
$69
Average ticket price on Oct 21
$71
Fastest journey on Oct 21
10 h 10 m
Average journey duration on Oct 21
11 h 56 m
Buses on Oct 21
5
Distance
709 km
Cheap tickets
The best way to find a cheap bus ticket from Orlando, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Greenville, SC will cost around $71 if you buy it on the day, but the cheapest tickets can be found for only $69.
Fast buses
It's difficult to get from Orlando, FL to Greenville, SC without transferring at least once.
FlixBus+
2:45 PM12h30Orlando, N John Young Pkwy (Greyhound Bus Station)3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$691One-way1 transfer- FlixBus · FlixBus9:30 AM12h00Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$691One-way1 transfer
- FlixBus+10:55 PM11h45Orlando, N John Young Pkwy (Greyhound Bus Station)10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$691One-way1 transfer
- FlixBus+2:00 PM13h15Orlando, The Florida Mall, FL3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$711One-way1 transfer
- FlixBus+8:50 PM10h10Orlando, N John Young Pkwy (Greyhound Bus Station)7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$741One-way1 transfer
- FlixBus+8:50 PM10h10Orlando, N John Young Pkwy (Greyhound Bus Station)7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$741One-way1 transfer
- FlixBus+10:55 PM11h45Orlando, N John Young Pkwy (Greyhound Bus Station)10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$691One-way1 transfer
- FlixBus · FlixBus9:30 AM12h00Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$691One-way1 transfer
- FlixBus+2:45 PM12h30Orlando, N John Young Pkwy (Greyhound Bus Station)3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$691One-way1 transfer
- FlixBus+2:00 PM13h15Orlando, The Florida Mall, FL3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$711One-way1 transfer
Journey information
Overview: Bus from Orlando, FL to Greenville, SC
USAUSA
Buses from Orlando, FL to Greenville, SC run on average 5 times per day, taking around 11h 47m. Cheap bus tickets for this journey start at $67 (€56) if you book in advance.
The earliest bus runs at 04:45, the last at 23:40. The fastest bus covers the 440 miles (709 km) distance in 9h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 440 miles (709 km) |
Average bus duration 11h 47m |
Cheapest ticket price $67 (€56) |
Buses per day 5 |
Fastest bus 9h 35m |
First bus 4:45 AM |
Last bus 11:40 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 35 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Orlando, FL to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:45AM | Arrival Time 07:35PM | Duration 14h50 | Departure days Mon, Fri, Sat, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 09:30PM | Duration 12h00 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 03:15AM | Duration 14h45 | Departure days Thu | Cheapest price $77 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 07:00AM | Duration 18h15 | Departure days Thu | Cheapest price $72 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 03:15AM | Duration 13h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 03:15AM | Duration 12h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 07:00AM | Duration 10h10 | Departure days Everyday | Cheapest price $74 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 10:40AM | Duration 11h45 | Departure days Everyday | Cheapest price $69 |
Live departures
Orlando, FL to Greenville, SC bus times
The table below shows live departures for Orlando, FL to Greenville, SC buses for today, Tuesday, October 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 9:30 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 12h00 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus+ | 2:00 PM Orlando, The Florida Mall, FL | 13h15 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus+ | 2:45 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 12h30 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus+ | 8:50 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 10h10 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Orlando, FL to Greenville, SC buses with Omio?
FlixBus as well as Greyhound offer buses services from Orlando, FL to Greenville, SC.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Greenville, SC.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Orlando, FL to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Greenville, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Orlando, FL to Greenville, SC.
Bus providers: FlixBus, Greyhound from Orlando, FL to Greenville, SCYou can travel by bus between Orlando, FL to Greenville, SC with FlixBus, Greyhound for as low as $67 (€56). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 35m
Cheapest FlixBus Price
$67 (€56)
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
9h 55m
Cheapest Greyhound Price
$75 (€62)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Greenville, SC
Things to do in Greenville, SC
Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
Greenville Center for Creative Arts
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
Metropolitan Arts Council Gallery
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
- Must visit
Falls Park on the Reedy
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
- Must visit
Main Street
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
- Recommended
Prisma Health Swamp Rabbit Trail
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
- Gluten-free
South Carolina Mustard-Style Barbecue
South Carolina barbecue is slow-smoked pork, often chopped or pulled, and classically served with the state’s distinctive mustard-based sauce.
- Gluten-free
Shrimp And Grits
Shrimp and grits pairs creamy stone-ground grits with shrimp, often enriched with bacon or sausage. It is a Lowcountry staple found across Greenville.
- Vegetarian
Fried Green Tomatoes
Fried green tomatoes are tart unripe tomatoes breaded and fried. They are a beloved Southern side and common on Upstate menus.
Henry's Smokehouse
Casual Greenville barbecue spot serving smoked meats, classic sides, and a relaxed neighborhood atmosphere.
Hall's Chophouse Greenville
Upscale downtown steakhouse and oyster bar with dry-aged beef, seafood, and an elegant supper-club feel.
Soby's
Refined Southern restaurant known for seasonal plates, thoughtful cocktails, and a polished downtown setting.
United States dollar ($)
Moderate for a U.S. city. Hotels and dining are usually cheaper than major metros, but car travel and limited transit can add to visitor costs.
Average meal costs
- Budget
- $10-15 for fast food or a casual meal.
- Mid-range
- $20-35 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for excellent service. Taxis usually get 10-15%. Cafes often have tip jars; $1-2 is common for drinks.
FAQs: Bus from Orlando, FL to Greenville, SC
Find answers to the most common questions about traveling from Orlando, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Orlando, FL to Greenville, SC can start from as little as $67 (€56) when you book in advance. The average bus ticket price for Orlando, FL to Greenville, SC is $101 (€84) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Greenville, SC is 9h 35m to travel the 440 miles (709 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Greenville, SC leaves at 4:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Greenville, SC leaves at 11:40 PM.
There are 5 buses a day from Orlando, FL to Greenville, SC which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Greenville, SC, you can count on FlixBus, Greyhound for the best way to get you to Greenville, SC. You can also check all possible bus companies who offer a service between Orlando, FL and Greenville, SC and compare the amenities they offer before buying a bus ticket.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL . When arriving in Greenville, SC , you can end your journey in bus stations like Greenville, Woodruff Rd ("Raceway" gas station), SC .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Greenville, Woodruff Rd ("Raceway" gas station), SC, located 8 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Orlando, FL and Greenville, SC including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Orlando, FL to Greenville, SC for bus company FlixBus, Greyhound.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Greenville, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Orlando, FL to Greenville, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Greenville, SC.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Greenville, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Greenville, SC:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Greenville, SC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Greenville, SC with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Orlando, FL to Greenville, SC with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Orlando, FL to Greenville, SC with the following bus company: FlixBus, Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Orlando, FL to Greenville, SC
Most Orlando, FL to Greenville, SC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Orlando, FL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Orlando
Arrival bus stations in Greenville
Which Orlando, FL station do buses to Greenville, SC leave from?
Buses from Orlando, FL to Greenville, SC leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $3 · every ~6 min
125 · 41m · $3 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $3 · every ~5 min
Which Greenville, SC station do buses from Orlando, FL arrive at?
Buses from Orlando, FL to Greenville, SC arrive at Greenville, Woodruff Rd ("Raceway" gas station). Greenville, Woodruff Rd ("Raceway" gas station) is 4 miles (8 km) from Greenville, SC city centre.
Greenville, Woodruff Rd ("Raceway" gas station)Woodruff Rd, Greenville, SC, USA
City-centre transport
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
TRUE
Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Orlando, FL
Most popular bus connections to Greenville, SC
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