4.9
4.6The cheapest and fastest buses from Orlando, FL to Greenville, SC
Cheapest price
$77
Average price
$84
Fastest journey
11 h 45 m
Average duration
13 h 4 m
Buses per day
5
Distance
709 km
The best way to find a cheap bus ticket from Orlando, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Greenville, SC will cost around $84 if you buy it on the day, but the cheapest tickets can be found for only $77.
It's difficult to get from Orlando, FL to Greenville, SC without transferring at least once.
FlixBus+
10:55 PM11h45Orlando, N John Young Pkwy (Greyhound Bus Station)10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$771One-way1 transfer- FlixBus · FlixBus9:00 AM12h30Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$781One-way1 transfer
- FlixBus · FlixBus+3:40 PM15h20Orlando, N John Young Pkwy (Greyhound Bus Station)7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$781One-way2 transfers
- FlixBus+2:00 PM13h15Orlando, The Florida Mall, FL3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$921One-way1 transfer
- FlixBus+2:45 PM12h30Orlando, N John Young Pkwy (Greyhound Bus Station)3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$941One-way1 transfer
- FlixBus+10:55 PM11h45Orlando, N John Young Pkwy (Greyhound Bus Station)10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$771One-way1 transfer
- FlixBus · FlixBus9:00 AM12h30Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$781One-way1 transfer
- FlixBus+2:45 PM12h30Orlando, N John Young Pkwy (Greyhound Bus Station)3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$941One-way1 transfer
- FlixBus+2:00 PM13h15Orlando, The Florida Mall, FL3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$921One-way1 transfer
- FlixBus · FlixBus+3:40 PM15h20Orlando, N John Young Pkwy (Greyhound Bus Station)7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$781One-way2 transfers
Travel Information
Compare bus, train, and flight for Orlando, FL to Greenville, SC
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $67. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a bus costs an average of $67, and a train costs an average of $137.
Distance: 440 miles (709 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$126 Average price Cheapest | $196 Average price | $226 Average price | $100 Average price (fuel + tolls) |
10h 20m Average total duration 9h 50m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 29h 13m Average total duration 28h 43m Onboard + 30m Additional time* | 7h 37m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Greenville, SC:
A bus is $70 (€58) less than a flight for this route with tickets for a flight from Orlando, FL to Greenville, SC costing on average $196 (€161).
A bus is $100 (€82) less than a train for this route with tickets for a train from Orlando, FL to Greenville, SC costing on average $226 (€185).
Other travel options to Greenville, SC take longer:
Bus takes on average 9h 50m.
Train takes on average 28h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Orlando, FL to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 03:15AM | Duration 22h40 | Departure days Thu | Cheapest price $105 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 09:30PM | Duration 12h30 | Departure days Wed, Thu | Cheapest price $78 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 09:30PM | Duration 12h00 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $81 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 03:15AM | Duration 14h45 | Departure days Thu | Cheapest price $106 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 07:00AM | Duration 18h15 | Departure days Thu | Cheapest price $91 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 03:15AM | Duration 13h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 03:15AM | Duration 12h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $84 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 07:00AM | Duration 15h20 | Departure days Wed | Cheapest price $78 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 07:00AM | Duration 14h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 10:40AM | Duration 11h45 | Departure days Everyday | Cheapest price $77 |
Live departures
Orlando, FL to Greenville, SC bus times
The table below shows live departures for Orlando, FL to Greenville, SC buses for today, Tuesday, July 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 2:00 PM Orlando, The Florida Mall, FL | 13h15 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus+ | 2:45 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 12h30 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus+ | 10:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 11h45 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| Wednesday, July 22 | |||||
| FlixBus · FlixBus | 9:00 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 12h30 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Orlando, FL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 22
Jul 23
Jul 24
Jul 25
Jul 26
Jul 27
Jul 28
Why should you book Orlando, FL to Greenville, SC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Orlando, FL to Greenville, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Orlando, FL to Greenville, SC.
Journey information
Overview: Bus from Orlando, FL to Greenville, SC
USAUSA
Buses from Orlando, FL to Greenville, SC run on average 5 times per day, taking around 9h 50m. Cheap bus tickets for this journey start at $67 (€55) but you can travel from only $56 (€46) by flight.
The earliest bus runs at 04:45, the last at 23:40. The fastest bus covers the 440 miles (709 km) distance in 10h 25m.
Distance 440 miles (709 km) |
Average bus duration 9h 50m |
Cheapest ticket price $67 (€55) |
Buses per day 5 |
Fastest bus 10h 25m |
First bus 4:45 AM |
Last bus 11:40 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Bus providers: Greyhound from Orlando, FL to Greenville, SCYou can travel by bus between Orlando, FL to Greenville, SC with Greyhound for as low as $56 (€46). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Orlando, FL to Greenville, SC
Find answers to the most common questions about traveling from Orlando, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Orlando, FL to Greenville, SC
Most Orlando, FL to Greenville, SC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Orlando, FL and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Getting to Orlando, The Florida Mall from Orlando city centre
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Orlando, FL
Most popular bus connections to Greenville, SC
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
