The cheapest and fastest buses from Florence, SC to Philadelphia, PA
Cheapest price
$165
Average price
$165
Fastest journey
14 h 30 m
Average duration
14 h 30 m
Buses per day
1
Distance
759 km
The best way to find a cheap bus ticket from Florence, SC to Philadelphia, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Philadelphia, PA will cost around $165 if you buy it on the day, but the cheapest tickets can be found for only $165.
Of the 1 buses that leave Florence, SC for Philadelphia, PA on Thu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct buses cover the 759 km distance in an average of 14 h 30 m but if you time it right, some buses will get you there in just 14 h 30 m .
On Thu, Feb 05 the slowest buses will take 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Florence, SC to Philadelphia, PA
Omio recommends booking the train as it is the most popular option from Florence, SC to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from €63. For those with little time consider booking a train which can get you there in 10h 53m. The ticket price range depends on the travel mode: a bus costs an average of €63, and a train costs an average of €97.
Distance: 471 miles (759 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€120 Average price Cheapest | €151 Average price |
11h 30m Average total duration 11h 0m Onboard + 30m Additional time* | 11h 23m Average total duration Fastest 10h 53m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Florence, SC to Philadelphia, PA bus times
The table below shows live departures for Florence, SC to Philadelphia, PA buses for tomorrow, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 PM Florence, SC | 14h30 | 10:45 AM Philadelphia, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Philadelphia, PA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Why should you book Florence, SC to Philadelphia, PA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Southeastern Stages to find the best option for your trip from Florence, SC to Philadelphia, PA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Philadelphia, PA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Philadelphia, PA.
Journey information
Overview: Bus from Florence, SC to Philadelphia, PA
Buses from Florence, SC to Philadelphia, PA run on average 6 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $79 (€63) if you book in advance.
The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 471 miles (759 km) distance in 11h 40m.
Distance 471 miles (759 km) |
Average bus duration 11h 0m |
Cheapest ticket price $79 (€63) |
Buses per day 6 |
Fastest bus 11h 40m |
First bus 00:05 |
Last bus 23:30 |
Bus providers: Greyhound, Southeastern Stages from Florence, SC to Philadelphia, PAYou can travel by bus between Florence, SC to Philadelphia, PA with Greyhound, Southeastern Stages for as low as $79 (€63). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Southeastern Stages
FAQs: Bus from Florence, SC to Philadelphia, PA
Find answers to the most common questions about traveling from Florence, SC to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
- Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
- Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
- Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
- Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
- Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
- Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
- Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
- Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
- Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Florence, SC to Philadelphia, PA
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Philadelphia, PA
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