The cheapest and fastest buses from Florence, SC to Philadelphia, PA
Cheapest price
$187
Average price
$214
Fastest journey
11 h 40 m
Average duration
14 h 41 m
Buses per day
9
Distance
759 km
The best way to find a cheap bus ticket from Florence, SC to Philadelphia, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Philadelphia, PA will cost around $214 if you buy it on the day, but the cheapest tickets can be found for only $187.
It's difficult to get from Florence, SC to Philadelphia, PA without transferring at least once.
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FlixBus · FlixBusTravel Information
Compare train and bus for Florence, SC to Philadelphia, PA
Omio recommends booking the train as it is the most popular option from Florence, SC to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from €53. For those with little time consider booking a train which can get you there in 10h 52m. The ticket price range depends on the travel mode: a bus costs an average of €53, and a train costs an average of €86.
Distance: 471 miles (759 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€84 Average price Cheapest | €116 Average price |
11h 30m Average total duration 11h 0m Onboard + 30m Additional time* | 11h 22m Average total duration Fastest 10h 52m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Florence, SC to Philadelphia, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 11:45AM | Duration 11h40 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $158 |
Operator Greyhound | Departure Time 11:20AM | Arrival Time 03:35AM | Duration 16h15 | Departure days Mon | Cheapest price $187 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 11:30AM | Duration 19h00 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $161 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 06:45AM | Duration 14h15 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $159 |
Live departures
Florence, SC to Philadelphia, PA bus times
The table below shows live departures for Florence, SC to Philadelphia, PA buses for today, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus · FlixBus | 9:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 16h15 | 1:45 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 2 transfers | |
undefined · undefined+ FlixBus · FlixBus | 9:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 19h00 | 4:30 PM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 3 transfers | |
undefined · undefined+ FlixBus · FlixBus | 9:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 19h45 | 5:15 PM Philadelphia, Callowhill St (Community College of Philadelphia Child Dev Center), PA | 3 transfers | |
+ FlixBus+![]() | 9:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 14h15 | 11:45 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 2 transfers | |
| Monday, December 22 | |||||
FlixBus · FlixBus | 5:05 AM Florence, W Lucas St (TA Gas Station), SC | 11h40 | 4:45 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 1 transfer | |
FlixBus+ undefined · undefined | 5:05 AM Florence, W Lucas St (TA Gas Station), SC | 16h15 | 9:20 PM Philadelphia, Schuylkill Ave (Cira Centre South), PA | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:05 AM Florence, W Lucas St (TA Gas Station), SC | 19h30 | 12:35 AM Philadelphia, Callowhill St (Community College of Philadelphia Child Dev Center), PA | 2 transfers | |
FlixBus+![]() | 5:05 AM Florence, W Lucas St (TA Gas Station), SC | 15h00 | 8:05 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 1 transfer | |
undefined · undefined+ FlixBus | 4:20 PM Florence, S Irby St (Greyhound Bus Stop), SC | 16h15 | 8:35 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Philadelphia, PA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
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Dec 28
Journey information
Overview: Bus from Florence, SC to Philadelphia, PA
Buses from Florence, SC to Philadelphia, PA run on average 5 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $66 (€53) if you book in advance.
The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 471 miles (759 km) distance in 12h 55m.
Distance 471 miles (759 km) |
Average bus duration 11h 0m |
Cheapest ticket price $66 (€53) |
Buses per day 5 |
Fastest bus 12h 55m |
First bus 00:05 |
Last bus 23:30 |
Bus providers: Greyhound, Southeastern Stages from Florence, SC to Philadelphia, PAYou can travel by bus between Florence, SC to Philadelphia, PA with Greyhound, Southeastern Stages for as low as $66 (€53). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Southeastern Stages
FAQs: Bus from Florence, SC to Philadelphia, PA
Find answers to the most common questions about traveling from Florence, SC to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
- Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
- Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
- Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
- Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
- Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
- Independence Hall, the historic site where the Declaration of Independence and the U. S. Constitution were debated and adopted
- Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
- Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
- Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Florence, SC to Philadelphia, PA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Florence, SC to Philadelphia, PA
More options for your journey from Florence, SC to Philadelphia, PA
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