Florence, SC to Philadelphia, PA bus with FlixBus

Sat, Sep 19
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Greyhound
FlixBus
Alsa
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Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Florence, SC to Philadelphia, PA

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

€125

Average ticket price on Sep 19

€125

Fastest journey on Sep 19

14 h 15 m

Average journey duration on Sep 19

14 h 15 m

Buses on Sep 19

1

Distance

759 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Philadelphia, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Philadelphia, PA will cost around €125 if you buy it on the day, but the cheapest tickets can be found for only €125.

Fast buses

On Sat, Sep 19, we found 1 buses from Florence, SC to Philadelphia, PA, including 1 direct services.

On Sat, Sep 19 the direct buses cover the 759 km distance in an average of 14 h 15 m but if you time it right, some buses will get you there in just 14 h 15 m .

On Sat, Sep 19 the slowest buses will take 14 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    8:30 PM14h15
    Florence, SC
    10:45 AMPhiladelphia, PA
    1251One-way
    0 transfers

Travel Information

Compare train, bus, and flight for Florence, SC to Philadelphia, PA

Omio recommends booking the flight as it is the most popular option from Florence, SC to Philadelphia, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €115 For those with little time, consider booking a flight, which has an average total journey time of 5h 56m. Average ticket prices depend on the travel mode: a bus costs an average of €115, while a flight costs an average of €666.

Distance: 471 miles (759 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

€115

Average price

Cheapest

€666

Average price

€205

Average price

€98

Average price

(fuel + tolls)

13h 19m

Average total duration

12h 49m

Onboard

+

30m

Additional time*

5h 56m

Average total duration

Fastest

3h 56m

Onboard

+

2h 0m

Additional time*

11h 0m

Average total duration

10h 30m

Onboard

+

30m

Additional time*

8h 37m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

American Airlines

Most popular airline

Amtrak

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence, SC to Philadelphia, PA is a bus with an average price of €115.

This is compared to other travel options from Florence, SC to Philadelphia, PA:

A bus is €91 less than a train for this route with tickets for a train from Florence, SC to Philadelphia, PA costing on average €205.

A bus is €552 less than a flight for this route with tickets for a flight from Florence, SC to Philadelphia, PA costing on average €666.

The fastest way to travel from Florence, SC to Philadelphia, PA is by flight with an average journey time of 3h 56m.

Other travel options to Philadelphia, PA take longer:

Train takes on average 10h 30m.

Bus takes on average 12h 49m.

It's helpful to compare your options as there are 3 ways to travel between Florence, SC and Philadelphia, PA including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Florence, SC to Philadelphia, PA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around €115 compared to roughly €98 in fuel and tolls — a saving of about €-16.60. The journey takes 12h 49m versus 8h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Florence, SC to Philadelphia, PA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
12:05AM
Arrival Time
11:45AM
Duration
11h40
Departure days
Mon, Fri
Cheapest price
75
Operator
FlixBus
Departure Time
08:30PM
Arrival Time
10:45AM
Duration
14h15
Departure days
Tue, Wed, Sat, Sun
Cheapest price
107
Operator
Greyhound
Departure Time
08:30PM
Arrival Time
03:30PM
Duration
19h00
Departure days
Thu
Cheapest price
88
Operator
Greyhound
Departure Time
09:30PM
Arrival Time
11:45AM
Duration
14h15
Departure days
Tue, Wed
Cheapest price
105

Compare prices and tickets Florence, SC to Philadelphia, PA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Florence, SC to Philadelphia, PA buses with Omio?

Greyhound as well as FlixBus offer buses services from Florence, SC to Philadelphia, PA.
Omio is an official ticket reseller for all your travel options from Florence, SC to Philadelphia, PA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Philadelphia, PA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence, SC to Philadelphia, PA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Philadelphia, PA.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Florence, SC to Philadelphia, PA.

Journey information

Overview: Bus from Florence, SC to Philadelphia, PA

USAUSA
USAUSA
Icon of bus

Buses from Florence, SC to Philadelphia, PA run on average 4 times per day, taking around 12h 49m. Cheap bus tickets for this journey start at €65 if you book in advance.

The earliest bus runs at 00:05, the last at 23:15. The fastest bus covers the 471 miles (759 km) distance in 10h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
471 miles (759 km)
Average bus duration
12h 49m
Cheapest ticket price
€65
Buses per day
4
Fastest bus
10h 25m
First bus
12:05 AM
Last bus
11:15 PM
Cheapest Month
Oct
Cheapest Day
Thu
High Season
Jul - Sep
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Florence, SC to Philadelphia, PAYou can travel by bus between Florence, SC to Philadelphia, PA with FlixBus, Greyhound for as low as €65. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 50m
Cheapest FlixBus Price
€67
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
10h 25m
Cheapest Greyhound Price
€65
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Philadelphia, PA

Things to do in Philadelphia, PA

Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.

  • Must visit

Philadelphia Museum of Art

World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.

  • Must visit

The Franklin Institute

Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.

  • Must visit

Barnes Foundation

Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.

US Dollar ($)

Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$20-40 per person for a restaurant meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$3-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.

FAQs: Bus from Florence, SC to Philadelphia, PA

Find answers to the most common questions about traveling from Florence, SC to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Philadelphia, PA can start from as little as €65 when you book in advance. The average bus ticket price for Florence, SC to Philadelphia, PA is €115 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Philadelphia, PA is 10h 25m to travel the 471 miles (759 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Philadelphia, PA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Philadelphia, PA leaves at 11:15 PM.
There are 4 buses a day from Florence, SC to Philadelphia, PA which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Philadelphia, PA, you can count on Greyhound, FlixBus for the best way to get you to Philadelphia, PA. You can also check all possible bus companies who offer a service between Florence, SC and Philadelphia, PA and compare the amenities they offer before buying a bus ticket.
When departing from Florence, SC , you have various bus station options to start your journey from including Florence, W Lucas St (TA Gas Station), SC, Florence, S Irby St (Greyhound Bus Stop), SC . When arriving in Philadelphia, PA , you can end your journey in bus stations like Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA, Philadelphia, Schuylkill Ave (Cira Centre South), PA, Philadelphia Bus Station, Camden, Walter Rand Transportation Center, Cherry Hill, NJ-38 (Cherry Hill Mall), Malvern, Matthews Road (Park and Ride off Matthews Road), PA .Passengers board the bus most frequently from Florence, W Lucas St (TA Gas Station), SC, which is located around 3 miles (6 km) away from the city centre, and they get off the bus at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA, located 2 away from the city centre.
A trip to Philadelphia, PA from Florence, SC is worth doing but not as a day trip with a journey time of 10h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Philadelphia, PA is October.
It's helpful to compare your options as there are 3 ways to travel between Florence, SC and Philadelphia, PA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Philadelphia, PA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Philadelphia, PA for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Philadelphia, PA are:
  • Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
  • Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
  • Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
  • Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
  • Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
The best things to do in Philadelphia, PA include:
  • Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
  • Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
  • Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
  • Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
  • Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from Florence, SC to Philadelphia, PA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Philadelphia, PA.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Philadelphia, PA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Philadelphia, PA:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Philadelphia, PA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Philadelphia, PA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Philadelphia, PA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Philadelphia, PA with the following bus company: Greyhound, FlixBus.
Since neither Florence, SC nor Philadelphia, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Florence, SC to Philadelphia, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Philadelphia, PA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Center City and tourist hotspots. Scams involving overpriced taxi rides or unlicensed transportation are common, so using reputable services or ride-sharing apps is advised. Travelers should also be wary of street vendors selling counterfeit goods and avoid displaying valuables openly to reduce risk. Staying aware of surroundings and using well-lit, populated routes enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Florence, SC to Philadelphia, PA

Most Florence, SC to Philadelphia, PA buses use the Florence, S Irby St (Greyhound Bus Stop) to Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) station pair, with some services arriving at Philadelphia, Greyhound Bus Station. Use this guide to compare Florence, SC and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Florence
Arrival bus stations in Philadelphia

Which Florence, SC station do buses to Philadelphia, PA leave from?

Buses from Florence, SC to Philadelphia, PA leave from Florence, W Lucas St (TA Gas Station). The station is 3 miles (6 km) from Florence, SC city centre at Florence, SC, USA.
Florence, W Lucas St (TA Gas Station)Florence, SC, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre

Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:

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Florence, W Lucas St (TA Gas Station) bus station facilities and services

Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Food and snacks available at the gas station.

Wi-Fi and ATMs

Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).

Tickets and information

Ticket office support is available at Florence, W Lucas St (TA Gas Station).

Parking, taxis and toilets

Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.

Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre

TRUE

Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services

Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).

Tickets and information

Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).

Parking, taxis and toilets

Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.

Most popular buses to and from Philadelphia, PA and Florence, SC

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