- Must visit
The Getty Center
Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.
Cheapest price on Sep 18
$246
Average ticket price on Sep 18
$300
Fastest journey on Sep 18
2 d 12 h 5 m
Average journey duration on Sep 18
2 d 15 h 33 m
Buses on Sep 18
2
Distance
3521 km
The best way to find a cheap bus ticket from Florence, SC to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Los Angeles, CA will cost around $300 if you buy it on the day, but the cheapest tickets can be found for only $246.
On Fri, Sep 18, we found 2 buses from Florence, SC to Los Angeles, CA, including 2 direct services.
On Fri, Sep 18 the direct buses cover the 3521 km distance in an average of 2 d 15 h 33 m but if you time it right, some buses will get you there in just 2 d 12 h 5 m .
On Fri, Sep 18 the slowest buses will take 2 d 19 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Florence, SC to Los Angeles, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $347 For those with little time, consider booking a bus, which has an average total journey time of 55h 57m. Average ticket prices depend on the travel mode: a bus costs an average of $347, while a train costs an average of $809.
Distance: 2187 miles (3521 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$347 Average price Cheapest | $809 Average price | $502 Average price (fuel + tolls) |
55h 57m Average total duration Fastest 55h 27m Onboard + 30m Additional time* | 69h 43m Average total duration 69h 13m Onboard + 30m Additional time* | 35h 49m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to Los Angeles, CA:
A bus is $412 (€337) less than a train for this route with tickets for a train from Florence, SC to Los Angeles, CA costing on average $788 (€645).
A bus is $453 (€371) less than a flight for this route with tickets for a flight from Florence, SC to Los Angeles, CA costing on average $830 (€679).
Other travel options to Los Angeles, CA take longer:
Bus takes on average 56h 12m.
Train takes on average 69h 31m.
Tickets start at around $376 (€308) compared to roughly $502 (€411) in fuel and tolls — a saving of about $126 (€103). The journey takes 56h 12m versus 35h 49m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:45AM | Arrival Time 10:50PM | Duration 60h05 | Departure days Thu, Fri | Cheapest price $231 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 05:30AM | Duration 57h20 | Departure days Mon, Sun | Cheapest price $296 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 10:30PM | Duration 74h00 | Departure days Mon, Wed, Thu | Cheapest price $275 |
Operator Greyhound | Departure Time 09:10PM | Arrival Time 06:30AM | Duration 57h20 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $230 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 11:00PM | Duration 73h30 | Departure days Wed | Cheapest price $286 |
The table below shows live departures for Florence, SC to Los Angeles, CA buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:45 AM Florence, SC | 60h05 | 10:50 PM Los Angeles, CA | 0 transfersDirect | |
![]() | 8:30 PM Florence, SC | 74h00 | 10:30 PM Los Angeles, CA | 0 transfersDirect | |
![]() | 9:10 PM Florence, SC | 57h20 | 6:30 AM Los Angeles, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence, SC to Los Angeles, CA run on average 4 times per day, taking around 55h 27m. Cheap bus tickets for this journey start at $258 (€211) if you book in advance.
The earliest bus runs at 09:35, the last at 23:30. The fastest bus covers the 2187 miles (3521 km) distance in 51h 35m.
Distance 2187 miles (3521 km) |
Average bus duration 55h 27m |
Cheapest ticket price $258 (€211) |
Buses per day 4 |
Fastest bus 51h 35m |
First bus 9:35 AM |
Last bus 11:30 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Los Angeles, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles, CA trip today.
Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.
Major contemporary art museum in Downtown LA, known for broad collections, special shows, and bold architecture.
World-class encyclopedic museum on Wilshire Boulevard, famous for diverse collections and the Urban Light installation.
Legendary boulevard known for the Walk of Fame, theaters, neon, and classic Hollywood atmosphere mixed with tourist energy.
Lively beachside promenade with street performers, Muscle Beach, and easy access to the Venice Boardwalk scene.
Major urban park with trails, the observatory, picnic areas, and some of the best public views in Los Angeles.
A bacon-wrapped hot dog grilled on a street cart and topped with peppers, onions, mustard, ketchup, and mayo. A late-night Los Angeles street food classic.
A French dip sandwich of thin-sliced roast beef on a roll, often dipped in meat jus. Los Angeles claims the original and locals still debate the best version.
Double corn tortillas filled with stewed beef, birria broth, onions, and cilantro. A beloved Los Angeles Mexican staple, especially popular from trucks and taquerias.
Acclaimed fine-dining restaurant serving a seasonal California tasting menu. Refined, intimate, and one of Los Angeles's most respected special-occasion venues.
Legendary taqueria known for charcoal-grilled carne asada tacos. Casual, fast-paced, and widely considered one of Los Angeles's essential taco stops.
Historic downtown deli linked to the French dip. Old-school counter service and classic sandwiches in a landmark Los Angeles setting.
Los Angeles is pricier than many U.S. cities for hotels, dining, parking, and rides. Budget options exist, but tourist areas and transport costs raise daily spend.
Tip 18-20% in restaurants, 15-20% for taxis or rideshares, and $1-2 at cafes for counter service or coffee.
Find answers to the most common questions about traveling from Florence, SC to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

Most Florence, SC to Los Angeles, CA buses use the Florence, S Irby St (Greyhound Bus Stop) to Los Angeles, Patsaouras Transit Plaza (Union Station) station pair, with some services arriving at Los Angeles, Cesar E Chavez / Vignes. Use this guide to compare Florence, SC and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food and snacks available at the gas station.
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food court and various dining options available.
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
Los Angeles, Cesar E Chavez / Vignes is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Cesar E Chavez / Vignes has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Los Angeles, Cesar E Chavez / Vignes. ATMs are available at Los Angeles, Cesar E Chavez / Vignes.
Ticket office support is available at Los Angeles, Cesar E Chavez / Vignes.
Available at Los Angeles, Cesar E Chavez / Vignes: Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Cesar E Chavez / Vignes: The station is accessible to people with disabilities.
Here are some other resources that might have the information you need