Travel Information
Compare train and bus for Florence, SC to Los Angeles, CA
Omio recommends booking the train as it is the most popular option from Florence, SC to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $231. For those with little time consider booking a bus which can get you there in 60h 29m. The ticket price range depends on the travel mode: a bus costs an average of $231, and a train costs an average of $518.
Distance: 2187 miles (3521 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$247 Average price Cheapest | $657 Average price |
60h 59m Average total duration Fastest 60h 29m Onboard + 30m Additional time* | 73h 42m Average total duration 73h 12m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Florence, SC to Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:45AM | Arrival Time 03:30PM | Duration 60h45 | Departure days Thu | Cheapest price $315 |
Operator Greyhound | Departure Time 04:10PM | Arrival Time 10:30PM | Duration 57h20 | Departure days Thu | Cheapest price $298 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 03:30PM | Duration 74h00 | Departure days Thu | Cheapest price $276 |
Live departures
Florence, SC to Los Angeles, CA bus times
The table below shows live departures for Florence, SC to Los Angeles, CA buses for today, Thursday, March 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined · undefined · undefined | 8:10 PM Florence, S Irby St (Greyhound Bus Stop), SC | 57h20 | 5:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3 transfers | |
+ FlixBus+ undefined · undefined | 8:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 74h00 | 10:30 PM Los Angeles, Cesar E Chavez / Vignes, CA | 5 transfers | |
+ FlixBus+ undefined · undefined | 8:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 63h40 | 12:10 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Los Angeles, CA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Florence, SC to Los Angeles, CA
Buses from Florence, SC to Los Angeles, CA run on average 5 times per day, taking around 60h 29m. Cheap bus tickets for this journey start at $231 (€188) if you book in advance.
The earliest bus runs at 08:45, the last at 23:30. The fastest bus covers the 2187 miles (3521 km) distance in 57h 20m.
Distance 2187 miles (3521 km) |
Average bus duration 60h 29m |
Cheapest ticket price $231 (€188) |
Buses per day 5 |
Fastest bus 57h 20m |
First bus 08:45 |
Last bus 23:30 |
Cheapest month Jun |
Cheapest day Thu |
High season Jan - Mar |
Low season Apr - Jun |
Bus providers: Southeastern Stages from Florence, SC to Los Angeles, CAYou can travel by bus between Florence, SC to Los Angeles, CA with Southeastern Stages for as low as $231 (€188). When you search for schedules and tickets, Omio will show you the best journey
Southeastern Stages
FAQs: Bus from Florence, SC to Los Angeles, CA
Find answers to the most common questions about traveling from Florence, SC to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
popular bus stations
Popular bus stations from Florence, SC to Los Angeles, CA
Most popular bus connections from Florence, SC
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