Florence, SC to Los Angeles, CA bus with Greyhound

Fri, Sep 18
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The cheapest and fastest buses from Florence, SC to Los Angeles, CA

Showing times, prices and bookable tickets for Sep 18

Cheapest price on Sep 18

$246

Average ticket price on Sep 18

$300

Fastest journey on Sep 18

2 d 12 h 5 m

Average journey duration on Sep 18

2 d 15 h 33 m

Buses on Sep 18

2

Distance

3521 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Los Angeles, CA will cost around $300 if you buy it on the day, but the cheapest tickets can be found for only $246.

Fast buses

On Fri, Sep 18, we found 2 buses from Florence, SC to Los Angeles, CA, including 2 direct services.

On Fri, Sep 18 the direct buses cover the 3521 km distance in an average of 2 d 15 h 33 m but if you time it right, some buses will get you there in just 2 d 12 h 5 m .

On Fri, Sep 18 the slowest buses will take 2 d 19 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    9:10 PM67h00
    Florence, SC
    4:10 PMLos Angeles, CA
    $2461One-way
    0 transfers
  • Greyhound
    10:45 AM60h05
    Florence, SC
    10:50 PMLos Angeles, CA
    $3531One-way
    0 transfers

Travel Information

Compare bus, train, and flight for Florence, SC to Los Angeles, CA

Omio recommends booking the train as it is the most popular option from Florence, SC to Los Angeles, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $347 For those with little time, consider booking a bus, which has an average total journey time of 55h 57m. Average ticket prices depend on the travel mode: a bus costs an average of $347, while a train costs an average of $809.

Distance: 2187 miles (3521 km)

Compare bus with

Bus
Most popular
Train
Driving

$347

Average price

Cheapest

$809

Average price

$502

Average price

(fuel + tolls)

55h 57m

Average total duration

Fastest

55h 27m

Onboard

+

30m

Additional time*

69h 43m

Average total duration

69h 13m

Onboard

+

30m

Additional time*

35h 49m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Amtrak

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence, SC to Los Angeles, CA is a bus with an average price of $376 (€308).

This is compared to other travel options from Florence, SC to Los Angeles, CA:

A bus is $412 (€337) less than a train for this route with tickets for a train from Florence, SC to Los Angeles, CA costing on average $788 (€645).

A bus is $453 (€371) less than a flight for this route with tickets for a flight from Florence, SC to Los Angeles, CA costing on average $830 (€679).

The fastest way to travel from Florence, SC to Los Angeles, CA is by flight with an average journey time of 6h 59m.

Other travel options to Los Angeles, CA take longer:

Bus takes on average 56h 12m.

Train takes on average 69h 31m.

It's helpful to compare your options as there are 3 ways to travel between Florence, SC and Los Angeles, CA including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Florence, SC to Los Angeles, CA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $376 (€308) compared to roughly $502 (€411) in fuel and tolls — a saving of about $126 (€103). The journey takes 56h 12m versus 35h 49m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Florence, SC to Los Angeles, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
10:45AM
Arrival Time
10:50PM
Duration
60h05
Departure days
Thu, Fri
Cheapest price
$231
Operator
Greyhound
Departure Time
08:10PM
Arrival Time
05:30AM
Duration
57h20
Departure days
Mon, Sun
Cheapest price
$296
Operator
Greyhound
Departure Time
08:30PM
Arrival Time
10:30PM
Duration
74h00
Departure days
Mon, Wed, Thu
Cheapest price
$275
Operator
Greyhound
Departure Time
09:10PM
Arrival Time
06:30AM
Duration
57h20
Departure days
Mon, Tue, Thu, Fri, Sun
Cheapest price
$230
Operator
Greyhound
Departure Time
09:30PM
Arrival Time
11:00PM
Duration
73h30
Departure days
Wed
Cheapest price
$286

Live departures

Florence, SC to Los Angeles, CA bus times

The table below shows live departures for Florence, SC to Los Angeles, CA buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound10:45 AM Florence, SC
60h05
10:50 PM Los Angeles, CA0 transfersDirect
Greyhound8:30 PM Florence, SC
74h00
10:30 PM Los Angeles, CA0 transfersDirect
Greyhound9:10 PM Florence, SC
57h20
6:30 AM Los Angeles, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence, SC to Los Angeles, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Sep 18
Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24

Why should you book Florence, SC to Los Angeles, CA buses with Omio?

Greyhound as well as FlixBus offer buses services from Florence, SC to Los Angeles, CA.
Omio is an official ticket reseller for all your travel options from Florence, SC to Los Angeles, CA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Los Angeles, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Florence, SC to Los Angeles, CA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Los Angeles, CA.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Florence, SC to Los Angeles, CA.

Journey information

Overview: Bus from Florence, SC to Los Angeles, CA

USAUSA
USAUSA
Icon of bus

Buses from Florence, SC to Los Angeles, CA run on average 4 times per day, taking around 55h 27m. Cheap bus tickets for this journey start at $258 (€211) if you book in advance.

The earliest bus runs at 09:35, the last at 23:30. The fastest bus covers the 2187 miles (3521 km) distance in 51h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
2187 miles (3521 km)
Average bus duration
55h 27m
Cheapest ticket price
$258 (€211)
Buses per day
4
Fastest bus
51h 35m
First bus
9:35 AM
Last bus
11:30 PM
Cheapest Month
Oct
Cheapest Day
Tue
High Season
Jan - Mar
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Florence, SC to Los Angeles, CAYou can travel by bus between Florence, SC to Los Angeles, CA with Greyhound for as low as $258 (€211). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
51h 35m
Cheapest Greyhound Price
$258 (€211)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Los Angeles, CA

Things to do in Los Angeles, CA

Discover the best of Los Angeles, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles, CA trip today.

  • Must visit

The Getty Center

Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.

  • Must visit

The Broad

Major contemporary art museum in Downtown LA, known for broad collections, special shows, and bold architecture.

  • Must visit

Los Angeles County Museum of Art

World-class encyclopedic museum on Wilshire Boulevard, famous for diverse collections and the Urban Light installation.

United States dollar ($)

Los Angeles is pricier than many U.S. cities for hotels, dining, parking, and rides. Budget options exist, but tourist areas and transport costs raise daily spend.

Average meal costs

Budget
$12-20 for fast food or casual takeaway.
Mid-range
$25-45 per person for a restaurant meal.
Fine dining
$80+ per person for upscale restaurants.
Coffee
$4-7 for coffee or cappuccino.

Tipping culture

Tip 18-20% in restaurants, 15-20% for taxis or rideshares, and $1-2 at cafes for counter service or coffee.

FAQs: Bus from Florence, SC to Los Angeles, CA

Find answers to the most common questions about traveling from Florence, SC to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Los Angeles, CA can start from as little as $258 (€211) when you book in advance. The average bus ticket price for Florence, SC to Los Angeles, CA is $347 (€284) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Los Angeles, CA is 51h 35m to travel the 2187 miles (3521 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Los Angeles, CA leaves at 9:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Los Angeles, CA leaves at 11:30 PM.
There are 4 buses a day from Florence, SC to Los Angeles, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Los Angeles, CA, you can count on Greyhound for the best way to get you to Los Angeles, CA. You can also check all possible bus companies who offer a service between Florence, SC and Los Angeles, CA and compare the amenities they offer before buying a bus ticket.
When departing from Florence, SC , you have various bus station options to start your journey from including Florence, S Irby St (Greyhound Bus Stop), SC, Florence, W Lucas St (TA Gas Station), SC . When arriving in Los Angeles, CA , you can end your journey in bus stations like Los Angeles, Patsaouras Transit Plaza (Union Station), CA, Los Angeles, Cesar E Chavez / Vignes, CA .Passengers board the bus most frequently from Florence, S Irby St (Greyhound Bus Stop), SC, which is located around away from the city centre, and they get off the bus at Los Angeles, Patsaouras Transit Plaza (Union Station), CA, located 1 away from the city centre.
A trip to Los Angeles, CA from Florence, SC is worth doing but not as a day trip with a journey time of 51h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Los Angeles, CA is October.
It's helpful to compare your options as there are 3 ways to travel between Florence, SC and Los Angeles, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Los Angeles, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Los Angeles, CA for bus company Greyhound.
Some of the most interesting sights to explore in Los Angeles, CA are:
  • Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
  • The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
  • Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
  • Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
  • Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
The best things to do in Los Angeles, CA include:
  • Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
  • Visit the historic El Capitan Theatre for a classic movie experience
  • Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
  • Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
  • Discover the unique exhibits at the Natural History Museum of Los Angeles County.
Whether you can cancel your bus ticket from Florence, SC to Los Angeles, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Los Angeles, CA.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Los Angeles, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Los Angeles, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Florence, SC to Los Angeles, CA.
You can reserve your seat on the bus from Florence, SC to Los Angeles, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Florence, SC to Los Angeles, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Florence, SC to Los Angeles, CA with the following bus company: Greyhound.
Since neither Florence, SC nor Los Angeles, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Florence, SC to Los Angeles, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Los Angeles, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas like Hollywood and Venice Beach. Common scams include fake ticket vendors near popular attractions and overcharging by unlicensed ride services. It's important to use official transportation options, stay aware of surroundings, and avoid sharing personal information with strangers to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Florence, SC to Los Angeles, CA

Most Florence, SC to Los Angeles, CA buses use the Florence, S Irby St (Greyhound Bus Stop) to Los Angeles, Patsaouras Transit Plaza (Union Station) station pair, with some services arriving at Los Angeles, Cesar E Chavez / Vignes. Use this guide to compare Florence, SC and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Florence
Arrival bus stations in Los Angeles

Which Florence, SC station do buses to Los Angeles, CA leave from?

Buses from Florence, SC to Los Angeles, CA leave from Florence, S Irby St (Greyhound Bus Stop). The station is 0 miles (1 km) from Florence, SC city centre at S Irby St, Florence, SC, USA.
Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre

TRUE

Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services

Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).

Tickets and information

Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).

Parking, taxis and toilets

Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.

Florence, W Lucas St (TA Gas Station)Florence, SC, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre

Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:

TRUE

Florence, W Lucas St (TA Gas Station) bus station facilities and services

Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Food and snacks available at the gas station.

Wi-Fi and ATMs

Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).

Tickets and information

Ticket office support is available at Florence, W Lucas St (TA Gas Station).

Parking, taxis and toilets

Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.

More options for your journey from Florence, SC to Los Angeles, CA

Here are some other resources that might have the information you need

Most popular buses to and from Los Angeles, CA and Florence, SC

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