- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
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The cheapest and fastest buses from Florence, SC to Orlando, FL
Showing times and prices for Aug 05
Cheapest price
$158
Average price
$158
Fastest journey
8 h 55 m
Average duration
8 h 55 m
Buses per day
1
Distance
647 km
Cheap tickets
The best way to find a cheap bus ticket from Florence, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Orlando, FL will cost around $158 if you buy it on the day, but the cheapest tickets can be found for only $158.
Fast buses
Of the 1 buses that leave Florence, SC for Orlando, FL on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 647 km distance in an average of 8 h 55 m but if you time it right, some buses will get you there in just 8 h 55 m .
On Wed, Aug 05 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
8:00 PM8h55Florence, SC4:55 AMOrlando, FL$1581One-way0 transfers
- 8:00 PM8h55Florence, SC4:55 AMOrlando, FL$1581One-way0 transfers
Journey information
Overview: Bus from Florence, SC to Orlando, FL
USAUSA
Buses from Florence, SC to Orlando, FL run on average 5 times per day, taking around 8h 35m. Cheap bus tickets for this journey start at $64 if you book in advance.
There are 2 buses per day. The earliest bus runs at 04:00, the last at 22:55. The fastest bus covers the 402 miles (647 km) distance in 8h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 402 miles (647 km) |
Average bus duration 8h 35m |
Cheapest ticket price $64 |
Buses per day 5 |
Direct buses 2 |
Fastest bus 8h 55m |
First bus 4:00 AM |
Last bus 10:55 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Florence, SC to Orlando, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 02:10PM | Duration 8h25 | Departure days Thu, Sat | Cheapest price $63 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 09:15PM | Duration 11h55 | Departure days Thu | Cheapest price $92 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 05:50AM | Duration 17h55 | Departure days Thu | Cheapest price $92 |
Operator Flixbus USA | Departure Time 04:00PM | Arrival Time 12:55AM | Duration 8h55 | Departure days Tue | Cheapest price $86 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 07:50AM | Duration 15h40 | Departure days Thu | Cheapest price $91 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 01:50AM | Duration 9h35 | Departure days Thu | Cheapest price $93 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 04:55AM | Duration 8h55 | Departure days Mon, Wed, Fri | Cheapest price $77 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 05:55AM | Duration 8h55 | Departure days Mon, Fri, Sun | Cheapest price $64 |
Why should you book Florence, SC to Orlando, FL buses with Omio?
FlixBus operates all buses services from Florence, SC to Orlando, FL.
Omio is an official ticket reseller for all your travel options from Florence, SC to Orlando, FL.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Orlando, FL.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Orlando, FL.
Bus providers: FlixBus from Florence, SC to Orlando, FLYou can travel by bus between Florence, SC to Orlando, FL with FlixBus for as low as $64. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
8h 55m
Cheapest Price
$64
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Orlando, FL
Things to do in Orlando, FL
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
- Recommended
Orange County Regional History Center
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
- Recommended
Rollins Museum of Art
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
- Must visit
Lake Eola Park
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
- Must visit
Park Avenue
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
- Recommended
Church Street District
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
Florida Catfish
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
- Gluten-free
Florida Shrimp
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
- Vegetarian
- Vegan
- Gluten-free
Cafecito
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Black Bean Deli
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Linda's La Cantina
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
The Ravenous Pig
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
US Dollar ($)
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Average meal costs
- Budget
- $10-15 for fast food or casual counter service.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
FAQs: Bus from Florence, SC to Orlando, FL
Find answers to the most common questions about traveling from Florence, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Florence, SC to Orlando, FL can start from as little as $64 when you book in advance. The average bus ticket price for Florence, SC to Orlando, FL is $85 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Orlando, FL is 8h 55m to travel the 402 miles (647 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Orlando, FL leaves at 4:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Orlando, FL leaves at 10:55 PM.
Yes, there are 2 direct buses a day from Florence, SC to Orlando, FL with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Florence, SC to Orlando, FL, you can count on FlixBus for the best way to get you to Orlando, FL. You can also check all possible bus companies who offer a service between Florence, SC and Orlando, FL and compare the amenities they offer before buying a bus ticket.
When departing from Florence, SC , you have various bus station options to start your journey from including Florence, S Irby St (Greyhound Bus Stop), SC, Florence, W Lucas St (TA Gas Station), SC . When arriving in Orlando, FL , you can end your journey in bus stations like Orlando, N John Young Pkwy (Greyhound Bus Station), Buena Ventura Lakes, Kissimmee, Orlando, The Florida Mall, FL .Passengers board the bus most frequently from Florence, S Irby St (Greyhound Bus Stop), SC, which is located around away from the city centre, and they get off the bus at Orlando, N John Young Pkwy (Greyhound Bus Station), located 3 away from the city centre.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Orlando, FL including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Orlando, FL:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Orlando, FL for bus company FlixBus.
Whether you can cancel your bus ticket from Florence, SC to Orlando, FL depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Orlando, FL.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Orlando, FL:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Orlando, FL:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Orlando, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Orlando, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Orlando, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Orlando, FL with the following bus company: FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Orlando, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like theme parks and popular tourist spots. Common scams include overpriced taxi rides, timeshare presentations that pressure visitors, and fake ticket sellers near major attractions. It's important to use authorized transportation services and purchase tickets from official vendors to avoid fraud. Additionally, travelers should stay aware of their surroundings and avoid poorly lit or isolated areas at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Florence, SC to Orlando, FL
Most Florence, SC to Orlando, FL buses use the Florence, S Irby St (Greyhound Bus Stop) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Florence, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Florence
Arrival bus stations in Orlando
Which Florence, SC station do buses to Orlando, FL leave from?
Buses from Florence, SC to Orlando, FL leave from Florence, S Irby St (Greyhound Bus Stop). The station is 0 miles (1 km) from Florence, SC city centre at S Irby St, Florence, SC, USA.
Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USA
City-centre transport
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
TRUE
Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Florence, W Lucas St (TA Gas Station)Florence, SC, USA
City-centre transport
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
TRUE
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Which Orlando, FL station do buses from Florence, SC arrive at?
Buses from Florence, SC to Orlando, FL most often arrive at Orlando, N John Young Pkwy (Greyhound Bus Station). Some services arrive at Buena Ventura Lakes, Kissimmee, so check your ticket before travel to confirm your Orlando, FL arrival station.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $2 · every ~5 min
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Orlando, FL
Here are some other resources that might have the information you need
Most popular buses to and from Orlando, FL and Florence, SC
Most popular bus connections to Orlando, FL
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