- Must visit
The Charles Hosmer Morse Museum of American Art
Outstanding museum in nearby Winter Park with the world's most comprehensive collection of works by Louis Comfort Tiffany.
Cheapest price
$64
Average price
$64
Fastest journey
8 h 55 m
Average duration
8 h 55 m
Buses per day
1
Distance
647 km
The best way to find a cheap bus ticket from Florence, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Orlando, FL will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $64.
Of the 1 buses that leave Florence, SC for Orlando, FL on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 647 km distance in an average of 8 h 55 m but if you time it right, some buses will get you there in just 8 h 55 m .
On Sun, Jun 21 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Florence, SC to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a bus which can get you there in 8h 35m. The ticket price range depends on the travel mode: a bus costs an average of $64, and a train costs an average of $67.
Distance: 402 miles (647 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$84 Average price Cheapest | $120 Average price | $91 Average price (fuel + tolls) |
9h 5m Average total duration Fastest 8h 35m Onboard + 30m Additional time* | 10h 7m Average total duration 9h 37m Onboard + 30m Additional time* | 6h 31m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence, SC to Orlando, FL:
A bus is $35 (€29) less than a train for this route with tickets for a train from Florence, SC to Orlando, FL costing on average $120 (€98).
Other travel options to Orlando, FL take longer:
Train takes on average 9h 37m.
Tickets start at around $84 (€69) compared to roughly $91 (€74) in fuel and tolls — a saving of about $6 (€5). The journey takes 8h 35m versus 6h 31m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:55AM | Arrival Time 05:50AM | Duration 17h55 | Departure days Tue | Cheapest price $101 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 07:50AM | Duration 15h40 | Departure days Tue | Cheapest price $108 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 01:50AM | Duration 9h35 | Departure days Tue | Cheapest price $108 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 04:55AM | Duration 8h55 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $69 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 05:55AM | Duration 8h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $64 |
The table below shows live departures for Florence, SC to Orlando, FL buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 PM Florence, SC | 8h55 | 4:55 AM Orlando, FL | 0 transfersDirect | |
![]() | 9:00 PM Florence, SC | 8h55 | 5:55 AM Orlando, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence, SC to Orlando, FL run on average 5 times per day, taking around 8h 35m. Cheap bus tickets for this journey start at $64 (€52) if you book in advance.
There are 2 buses per day. The earliest bus runs at 04:00, the last at 22:55. The fastest bus covers the 402 miles (647 km) distance in 8h 55m.
Distance 402 miles (647 km) |
Average bus duration 8h 35m |
Cheapest ticket price $64 (€52) |
Buses per day 5 |
Direct buses 2 |
Fastest bus 8h 55m |
First bus 4:00 AM |
Last bus 10:55 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Orlando — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando trip today.
Outstanding museum in nearby Winter Park with the world's most comprehensive collection of works by Louis Comfort Tiffany.
Major art museum in Loch Haven Park with American art, African art, and rotating exhibitions. A strong all-round cultural stop in Orlando.
History museum in a restored 1927 courthouse covering Central Florida's past through engaging permanent and temporary exhibits.
Signature downtown park with a walking loop, swan boats, skyline views, and frequent events. One of Orlando's easiest must-see areas.
Elegant shopping and strolling district lined with trees, boutiques, and public art. Popular for a more refined local side of Orlando.
Highly popular open-air entertainment district known for themed design, shops, and waterfront atmosphere. Very popular with visitors and influencers.
Florida’s signature dessert made with tart key lime filling in a crumb crust, often topped with whipped cream. It is a classic sweet treat across Orlando and Central Florida.
A seasonal Florida seafood specialty, usually served chilled with mustard sauce. It is prized for sweet, firm claw meat and is strongly associated with the state’s coastal food culture.
Fried alligator pieces, usually lightly breaded and served with dipping sauce. This is a distinctly Floridian dish that appears on many casual local menus.
A respected Orlando restaurant blending traditional Japanese technique with creative modern sushi and omakase-style options in a stylish setting.
A well-known gastropub in Winter Park serving refined Southern-inspired American dishes, craft beer, and seasonal Florida ingredients in a lively but polished setting.
A popular bakery and comfort food spot known for Southern breakfast, biscuits, pies, and nostalgic desserts. Casual, friendly, and highly regarded by locals.
Moderate overall. Theme parks and resort areas are pricey, but chain restaurants and casual dining offer better value.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxi/rideshare 10-15%, hotel staff USD 2-5, and round up for cafes if desired.
Find answers to the most common questions about traveling from Florence, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Florence, SC to Orlando, FL buses use the Florence, S Irby St (Greyhound Bus Stop) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Buena Ventura Lakes, Kissimmee. Use this guide to compare Florence, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need