The cheapest and fastest buses from Florence, SC to Orlando, FL
Cheapest price
$97
Average price
$97
Fastest journey
8 h 25 m
Average duration
8 h 25 m
Buses per day
1
Distance
647 km
The best way to find a cheap bus ticket from Florence, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Orlando, FL will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $97.
Of the 1 buses that leave Florence, SC for Orlando, FL on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 647 km distance in an average of 8 h 25 m but if you time it right, some buses will get you there in just 8 h 25 m .
On Fri, Nov 07 the slowest buses will take 8 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Florence, SC to Orlando, FL
Omio recommends booking the train as it is the most popular option from Florence, SC to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from €61. For those with little time consider booking a train which can get you there in 9h 32m. The ticket price range depends on the travel mode: a bus costs an average of €61, and a train costs an average of €67.
Distance: 402 miles (647 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€69 Average price Cheapest | €77 Average price |
11h 21m Average total duration 10h 51m Onboard + 30m Additional time* | 10h 2m Average total duration Fastest 9h 32m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Florence, SC to Orlando, FL bus times
The table below shows live departures for Florence, SC to Orlando, FL buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:55 PM Florence, SC | 11h40 | 4:35 AM Orlando, FL | 0 transfersDirect | |
| Friday, November 7 | |||||
![]() | 9:35 AM Florence, SC | 8h25 | 6:00 PM Orlando, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Orlando, FL by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Bus from Florence, SC to Orlando, FL
Buses from Florence, SC to Orlando, FL run on average 2 times per day, taking around 10h 51m. Cheap bus tickets for this journey start at $75 (€61) if you book in advance.
There are 1 buses per day. The earliest bus runs at 04:00, the last at 22:30. The fastest bus covers the 402 miles (647 km) distance in 8h 25m.
Distance 402 miles (647 km) |
Average bus duration 10h 51m |
Cheapest ticket price $75 (€61) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 8h 25m |
First bus 04:00 |
Last bus 22:30 |
Bus providers: FlixBus from Florence, SC to Orlando, FLYou can travel by bus between Florence, SC to Orlando, FL with FlixBus for as low as $75 (€61). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Florence, SC to Orlando, FL
Find answers to the most common questions about traveling from Florence, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Walt Disney World Resort, a massive entertainment complex featuring theme parks, water parks, and resorts
- Universal Orlando Resort, a popular destination with thrilling rides, shows, and attractions based on movies and TV shows
- SeaWorld Orlando, a marine-themed park offering animal exhibits, shows, and rides
- Kennedy Space Center Visitor Complex, an educational attraction showcasing NASA's space exploration history and offering interactive exhibits
- Leu Gardens, a beautiful botanical garden with a variety of plant collections and scenic landscapes.
- ICON Park, a vibrant entertainment complex with dining, shopping, and the iconic Wheel for panoramic views
- Explore the vibrant nightlife and live entertainment at Church Street District
- Enjoy a day of shopping and dining at The Mall at Millenia
- Experience the natural beauty and wildlife at Wekiwa Springs State Park
- Visit the Orlando Science Center for interactive exhibits and planetarium shows.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Florence, SC to Orlando, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Florence, SC to Orlando, FL
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