Journey information
Overview: Bus from Houston, TX to Greenville, SC
Take a bus from Houston, TX to Greenville, SC and enjoy the approximately 833 miles (1342 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 02:23, the last at 23:45.
Distance 833 miles (1342 km) |
Average bus duration 19h 28m |
Buses per day 9 |
First bus 02:23 |
Last bus 23:45 |
Bus providers: FlixBus, Greyhound from Houston, TX to Greenville, SCYou can travel by bus between Houston, TX to Greenville, SC with FlixBus, Greyhound. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Houston, TX to Greenville, SC
Find answers to the most common questions about traveling from Houston, TX to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Houston, TX to Greenville, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Houston, TX to Greenville, SC
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