- Must visit
Greenville County Museum Of Art
Major local art museum known for Southern art and a strong Andrew Wyeth collection. A top cultural stop in downtown Greenville.
Cheapest price
$173
Average price
$202
Fastest journey
20 h 35 m
Average duration
23 h 17 m
Buses per day
7
Distance
1342 km
The best way to find a cheap bus ticket from Houston, TX to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Houston, TX to Greenville, SC will cost around $202 if you buy it on the day, but the cheapest tickets can be found for only $173.
It's difficult to get from Houston, TX to Greenville, SC without transferring at least once.
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· Omio recommends booking the flight as it is the most popular option from Houston, TX to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $121. For those with little time consider booking a flight which can get you there in 2h 23m. The ticket price range depends on the travel mode: a bus costs an average of $121, and a flight costs an average of $206.
Distance: 833 miles (1342 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$205 Average price Cheapest | $335 Average price | $303 Average price | $188 Average price (fuel + tolls) |
19h 58m Average total duration 19h 28m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 2h 23m Onboard + 3h 0m Additional time* | 37h 38m Average total duration 37h 8m Onboard + 30m Additional time* | 13h 39m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Houston, TX to Greenville, SC:
A bus is $98 (€81) less than a train for this route with tickets for a train from Houston, TX to Greenville, SC costing on average $303 (€249).
A bus is $130 (€107) less than a flight for this route with tickets for a flight from Houston, TX to Greenville, SC costing on average $335 (€276).
Other travel options to Greenville, SC take longer:
Bus takes on average 19h 28m.
Train takes on average 37h 8m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:00AM | Arrival Time 03:15AM | Duration 21h15 | Departure days Everyday | Cheapest price $136 |
Operator Greyhound | Departure Time 06:35AM | Arrival Time 09:30PM | Duration 37h55 | Departure days Everyday | Cheapest price $138 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 10:40AM | Duration 24h40 | Departure days Tue, Wed | Cheapest price $160 |
Operator Greyhound | Departure Time 10:25AM | Arrival Time 09:30PM | Duration 34h05 | Departure days Thu | Cheapest price $180 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 10:40AM | Duration 20h35 | Departure days Everyday | Cheapest price $136 |
Operator Greyhound | Departure Time 01:15PM | Arrival Time 09:30PM | Duration 31h15 | Departure days Tue | Cheapest price $164 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 10:40AM | Duration 20h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $136 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 09:30PM | Duration 30h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $141 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 09:30PM | Duration 30h20 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $151 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 03:15AM | Duration 32h15 | Departure days Tue | Cheapest price $200 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 09:30PM | Duration 22h30 | Departure days Everyday | Cheapest price $138 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 03:15AM | Duration 27h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $144 |
The table below shows live departures for Houston, TX to Greenville, SC buses for today, Tuesday, July 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 10:00 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 22h30 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| Wednesday, July 8 | |||||
· | 5:00 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 21h15 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
· + FlixBus+![]() | 6:35 AM Houston, Southwest Fwy (Chevron), TX | 37h55 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
FlixBus+ · | 9:00 AM Houston, Gray St Parking (Bus Station), TX | 24h40 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
· | 1:05 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 20h35 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
FlixBus+ · + FlixBus | 2:10 PM Houston, Gray St Parking (Bus Station), TX | 30h20 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Houston, TX to Greenville, SC run on average 10 times per day, taking around 19h 28m. Cheap bus tickets for this journey start at $121 (€100) if you book in advance.
The earliest bus runs at 02:23, the last at 23:25. The fastest bus covers the 833 miles (1342 km) distance in 22h 55m.
Distance 833 miles (1342 km) |
Average bus duration 19h 28m |
Cheapest ticket price $121 (€100) |
Buses per day 10 |
Fastest bus 22h 55m |
First bus 2:23 AM |
Last bus 11:25 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jan - Mar |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Major local art museum known for Southern art and a strong Andrew Wyeth collection. A top cultural stop in downtown Greenville.
History museum covering the Upstate region with rotating exhibitions and family-friendly displays on local culture and heritage.
Specialized museum with notable historic instruments and performance-related exhibits. A distinctive stop for music and design lovers.
The heart of downtown Greenville, lined with shops, public art, plazas, and lively pedestrian-friendly blocks.
Landscaped riverfront park with trails, gardens, overlooks, and easy access to downtown. Essential for first-time visitors.
Popular multi-use greenway for walking and cycling, connecting Greenville with nearby districts and scenic stretches.
A Lowcountry classic of creamy grits topped with shrimp, often finished with bacon, gravy, or a light sauce. It is one of the best-known regional dishes in Upstate and coastal South Carolina cooking.
Slices of unripe tomatoes coated and fried until crisp, often served with remoulade or pimento cheese. This Southern staple is common on Greenville menus and highlights classic regional comfort food.
A spread made from cheddar, pimentos, and mayonnaise, served with crackers, toast, or as a sandwich filling. It is a signature Southern snack strongly associated with South Carolina food culture.
A respected neighborhood restaurant focused on seasonal ingredients and thoughtful Southern-influenced cooking in a relaxed setting.
A long-established downtown restaurant known for refined Southern cooking, shrimp and grits, and a polished yet approachable atmosphere.
An established upscale restaurant with handmade pasta, oysters, and strong city views, suited for a more polished dinner in Greenville.
Moderate for U.S. travel. Meals and coffee are fairly priced, while hotels vary by season and events.
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Houston, TX to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

Most Houston, TX to Greenville, SC buses use the Houston, Harrisburg Blvd (Greyhound Bus Station) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Houston, TX and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need