The cheapest and fastest buses from Houston, TX to Greenville, SC
Cheapest price
$142
Average price
$146
Fastest journey
20 h 35 m
Average duration
1 d 47 m
Buses per day
7
Distance
1342 km
The best way to find a cheap bus ticket from Houston, TX to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Houston, TX to Greenville, SC will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $142.
It's difficult to get from Houston, TX to Greenville, SC without transferring at least once.
· +
FlixBus+
6:35 AM38h20Houston, Southwest Fwy (Chevron), TX9:55 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1421One-way3 transfers
· 5:00 AM25h00Houston, Harrisburg Blvd (Greyhound Bus Station), TX7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1421One-way1 transfer
+
FlixBus10:00 PM22h55Houston, Harrisburg Blvd (Greyhound Bus Station), TX9:55 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1471One-way1 transfer
FlixBus+
· 9:00 AM24h40Houston, Gray St Parking (Bus Station), TX10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1481One-way2 transfers
FlixBus+
· +
FlixBus2:10 PM30h45Houston, Gray St Parking (Bus Station), TX9:55 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1491One-way3 transfers
· 1:05 PM20h35Houston, Harrisburg Blvd (Greyhound Bus Station), TX10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1491One-way1 transfer
+
FlixBus10:00 PM22h55Houston, Harrisburg Blvd (Greyhound Bus Station), TX9:55 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1471One-way1 transfer
FlixBus+
· 9:00 AM24h40Houston, Gray St Parking (Bus Station), TX10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1481One-way2 transfers
· 5:00 AM25h00Houston, Harrisburg Blvd (Greyhound Bus Station), TX7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1421One-way1 transfer
FlixBus+
· +
FlixBus2:10 PM30h45Houston, Gray St Parking (Bus Station), TX9:55 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1491One-way3 transfers
Travel Information
Compare bus, flight, and train for Houston, TX to Greenville, SC
Omio recommends booking the flight as it is the most popular option from Houston, TX to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $123. For those with little time consider booking a flight which can get you there in 2h 23m. The ticket price range depends on the travel mode: a bus costs an average of $123, and a flight costs an average of $209.
Distance: 833 miles (1342 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$209 Average price Cheapest | $341 Average price | $308 Average price | $191 Average price (fuel + tolls) |
19h 58m Average total duration 19h 28m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 2h 23m Onboard + 3h 0m Additional time* | 37h 38m Average total duration 37h 8m Onboard + 30m Additional time* | 13h 39m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Houston, TX to Greenville, SC:
A bus is $100 (€81) less than a train for this route with tickets for a train from Houston, TX to Greenville, SC costing on average $308 (€249).
A bus is $132 (€107) less than a flight for this route with tickets for a flight from Houston, TX to Greenville, SC costing on average $341 (€276).
Other travel options to Greenville, SC take longer:
Bus takes on average 19h 28m.
Train takes on average 37h 8m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Houston, TX to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:50AM | Arrival Time 11:00AM | Duration 34h10 | Departure days Sat | Cheapest price $143 |
Operator Greyhound | Departure Time 03:00AM | Arrival Time 01:55AM | Duration 22h55 | Departure days Fri | Cheapest price $174 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 11:00AM | Duration 31h10 | Departure days Fri, Sat | Cheapest price $197 |
Operator Greyhound | Departure Time 05:00AM | Arrival Time 07:00AM | Duration 25h00 | Departure days Wed, Sat | Cheapest price $142 |
Operator Greyhound | Departure Time 06:35AM | Arrival Time 09:55PM | Duration 38h20 | Departure days Wed, Sat | Cheapest price $142 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 10:40AM | Duration 24h40 | Departure days Wed | Cheapest price $148 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 10:40AM | Duration 20h35 | Departure days Wed, Sat | Cheapest price $149 |
Operator Greyhound | Departure Time 01:15PM | Arrival Time 10:40AM | Duration 20h25 | Departure days Sat | Cheapest price $151 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 09:55PM | Duration 31h15 | Departure days Sat | Cheapest price $155 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 10:40AM | Duration 19h55 | Departure days Sat | Cheapest price $151 |
Operator Greyhound | Departure Time 01:50PM | Arrival Time 09:55PM | Duration 31h05 | Departure days Sat | Cheapest price $165 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 09:55PM | Duration 30h45 | Departure days Wed, Sat | Cheapest price $149 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 01:55AM | Duration 31h05 | Departure days Fri, Sun | Cheapest price $241 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 07:00AM | Duration 34h10 | Departure days Sat | Cheapest price $153 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 09:55PM | Duration 22h55 | Departure days Wed, Sat | Cheapest price $147 |
Operator FlixBus | Departure Time 10:50PM | Arrival Time 07:00AM | Duration 31h10 | Departure days Wed, Sat | Cheapest price $150 |
Live departures
Houston, TX to Greenville, SC bus times
The table below shows live departures for Houston, TX to Greenville, SC buses for tomorrow, Wednesday, May 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 5:00 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 25h00 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
· + FlixBus+![]() | 6:35 AM Houston, Southwest Fwy (Chevron), TX | 38h20 | 9:55 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 3 transfers | |
FlixBus+ · | 9:00 AM Houston, Gray St Parking (Bus Station), TX | 24h40 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Houston, TX to Greenville, SC by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 20
May 21
May 22
May 23
May 24
May 25
May 26
Why should you book Houston, TX to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Houston, TX to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Houston, TX to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Houston, TX to Greenville, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Houston, TX to Greenville, SC.
Journey information
Overview: Bus from Houston, TX to Greenville, SC
Buses from Houston, TX to Greenville, SC run on average 10 times per day, taking around 19h 28m. Cheap bus tickets for this journey start at $123 (€100) if you book in advance.
The earliest bus runs at 02:23, the last at 23:25. The fastest bus covers the 833 miles (1342 km) distance in 22h 55m.
Distance 833 miles (1342 km) |
Average bus duration 19h 28m |
Cheapest ticket price $123 (€100) |
Buses per day 10 |
Fastest bus 22h 55m |
First bus 2:23 AM |
Last bus 11:25 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jan - Mar |
Bus providers: FlixBus, Greyhound from Houston, TX to Greenville, SCYou can travel by bus between Houston, TX to Greenville, SC with FlixBus, Greyhound for as low as $123 (€100). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Houston, TX to Greenville, SC
Find answers to the most common questions about traveling from Houston, TX to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Houston, TX to Greenville, SC
More options for your journey from Houston, TX to Greenville, SC
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