The cheapest and fastest buses from Greensboro, NC to Greenville, SC
Cheapest price
$45
Average price
$45
Fastest journey
3 h 45 m
Average duration
3 h 45 m
Buses per day
1
Distance
272 km
The best way to find a cheap bus ticket from Greensboro, NC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to Greenville, SC will cost around $45 if you buy it on the day, but the cheapest tickets can be found for only $45.
Of the 1 buses that leave Greensboro, NC for Greenville, SC on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct buses cover the 272 km distance in an average of 3 h 45 m but if you time it right, some buses will get you there in just 3 h 45 m .
On Tue, Dec 23 the slowest buses will take 3 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Greensboro, NC to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Greensboro, NC to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €34. For those with little time consider booking a bus which can get you there in 4h 18m. The ticket price range depends on the travel mode: a bus costs an average of €34, and a flight costs an average of €334.
Distance: 169 miles (272 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€37 Average price Cheapest | €66 Average price | €413 Average price |
4h 48m Average total duration Fastest 4h 18m Onboard + 30m Additional time* | 5h 25m Average total duration 4h 55m Onboard + 30m Additional time* | 9h 10m Average total duration 6h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Greensboro, NC to Greenville, SC bus times
The table below shows live departures for Greensboro, NC to Greenville, SC buses for today, Monday, December 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:50 PM Greensboro, NC | 3h50 | 11:40 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greensboro, NC to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 23
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Dec 29
Journey information
Overview: Bus from Greensboro, NC to Greenville, SC
Buses from Greensboro, NC to Greenville, SC run on average 4 times per day, taking around 4h 18m. Cheap bus tickets for this journey start at $42 (€34) if you book in advance.
There are 4 buses per day. The earliest bus runs at 04:50, the last at 22:15. The fastest bus covers the 169 miles (272 km) distance in 3h 40m.
Distance 169 miles (272 km) |
Average bus duration 4h 18m |
Cheapest ticket price $42 (€34) |
Buses per day 4 |
Direct buses 4 |
Fastest bus 3h 40m |
First bus 04:50 |
Last bus 22:15 |
Bus providers: FlixBus, Greyhound from Greensboro, NC to Greenville, SCYou can travel by bus between Greensboro, NC to Greenville, SC with FlixBus, Greyhound for as low as $42 (€34). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Greensboro, NC to Greenville, SC
Find answers to the most common questions about traveling from Greensboro, NC to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Greensboro, NC to Greenville, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Greensboro, NC to Greenville, SC
Most popular bus connections from Greensboro, NC
More options for your journey from Greensboro, NC to Greenville, SC
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