- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Cheapest price
$36
Average price
$45
Fastest journey
3 h 40 m
Average duration
5 h 17 m
Buses per day
5
Distance
272 km
The best way to find a cheap bus ticket from Greensboro, NC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to Greenville, SC will cost around $45 if you buy it on the day, but the cheapest tickets can be found for only $36.
Of the 5 buses that leave Greensboro, NC for Greenville, SC on Mon, Jun 22, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 272 km distance in an average of 5 h 17 m but if you time it right, some buses will get you there in just 3 h 40 m .
On Mon, Jun 22 the slowest buses will take 9 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the train as it is the most popular option from Greensboro, NC to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a bus which can get you there in 4h 18m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $188.
Distance: 169 miles (272 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$43 Average price Cheapest | $74 Average price | $369 Average price | $39 Average price (fuel + tolls) |
4h 48m Average total duration Fastest 4h 18m Onboard + 30m Additional time* | 5h 23m Average total duration 4h 53m Onboard + 30m Additional time* | 8h 13m Average total duration 5h 13m Onboard + 3h 0m Additional time* | 2h 48m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greensboro, NC to Greenville, SC:
A bus is $31 (€26) less than a train for this route with tickets for a train from Greensboro, NC to Greenville, SC costing on average $74 (€61).
A bus is $326 (€266) less than a flight for this route with tickets for a flight from Greensboro, NC to Greenville, SC costing on average $369 (€302).
Other travel options to Greenville, SC take longer:
Train takes on average 4h 53m.
Flight takes on average 5h 13m.
You'll arrive about -2h -30m sooner (4h 18m by bus vs 2h 48m by car) and save roughly $-4.51 (€-3.69) compared to fuel and tolls ($43 (€35) vs $39 (€32)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus, Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:05AM | Arrival Time 12:35PM | Duration 9h30 | Departure days Tue | Cheapest price $60 |
Operator FlixBus | Departure Time 04:05AM | Arrival Time 01:35PM | Duration 9h30 | Departure days Fri | Cheapest price $40 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 08:35AM | Duration 3h40 | Departure days Fri | Cheapest price $31 |
Operator Greyhound | Departure Time 06:05AM | Arrival Time 10:50AM | Duration 4h45 | Departure days Fri | Cheapest price $34 |
Operator FlixBus | Departure Time 08:55AM | Arrival Time 12:35PM | Duration 3h40 | Departure days Mon, Wed, Thu, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 01:15PM | Duration 3h45 | Departure days Fri | Cheapest price $40 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 01:35PM | Duration 3h40 | Departure days Thu, Sat | Cheapest price $37 |
Operator Greyhound | Departure Time 10:05AM | Arrival Time 02:50PM | Duration 4h45 | Departure days Mon, Wed, Thu | Cheapest price $41 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 03:50PM | Duration 4h45 | Departure days Mon, Tue | Cheapest price $36 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 05:15PM | Duration 3h45 | Departure days Thu | Cheapest price $51 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 06:15PM | Duration 3h45 | Departure days Wed | Cheapest price $39 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 07:25PM | Duration 3h45 | Departure days Fri | Cheapest price $34 |
Operator Greyhound | Departure Time 03:45PM | Arrival Time 08:10PM | Duration 4h25 | Departure days Fri | Cheapest price $35 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 12:25AM | Duration 3h45 | Departure days Mon, Sat, Sun | Cheapest price $47 |
The table below shows live departures for Greensboro, NC to Greenville, SC buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:55 AM Greensboro, NC | 3h40 | 12:35 PM Greenville, SC | 0 transfersDirect | |
![]() | 8:40 PM Greensboro, NC | 3h45 | 12:25 AM Greenville, SC | 0 transfersDirect | |
| Monday, June 22 | |||||
![]() | 3:05 AM Greensboro, NC | 9h30 | 12:35 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greensboro, NC to Greenville, SC run on average 3 times per day, taking around 4h 18m. Cheap bus tickets for this journey start at $34 (€27) if you book in advance.
There are 3 buses per day. The earliest bus runs at 04:55, the last at 22:15. The fastest bus covers the 169 miles (272 km) distance in 3h 40m.
Distance 169 miles (272 km) |
Average bus duration 4h 18m |
Cheapest ticket price $34 (€27) |
Buses per day 3 |
Direct buses 3 |
Fastest bus 3h 40m |
First bus 4:55 AM |
Last bus 10:15 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sun |
Least Busy Day Sat |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Greensboro, NC to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

Most Greensboro, NC to Greenville, SC buses use the Greensboro, E Washington St (Greyhound Bus Station) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Greensboro, NC and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need