- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
The best way to find a cheap bus ticket from Greensboro, NC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greensboro, NC to Greenville, SC will cost around L 212 if you buy it on the day, but the cheapest tickets can be found for only L 188.
On Fri, Nov 06, we found 5 buses from Greensboro, NC to Greenville, SC, including 5 direct services.
On Fri, Nov 06 the direct buses cover the 272 km distance in an average of 5 h 4 m but if you time it right, some buses will get you there in just 3 h 40 m .
On Fri, Nov 06 the slowest buses will take 9 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Greensboro, NC to Greenville, SC run on average 4 times per day, taking around 4h 5m. Cheap bus tickets for this journey start at L 143 if you book in advance.
There are 4 buses per day. The earliest bus runs at 04:55, the last at 22:15. The fastest bus covers the 169 miles (272 km) distance in 3h 40m.
Distance 169 miles (272 km) |
Average bus duration 4h 5m |
Cheapest ticket price L 143 |
Buses per day 4 |
Direct buses 4 |
Fastest bus 3h 40m |
First bus 4:55 AM |
Last bus 10:15 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Sat |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greensboro, NC to Greenville, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:05AM | Arrival Time 12:35PM | Duration 9h30 | Departure days Tue | Cheapest price L 279 |
Operator FlixBus | Departure Time 04:05AM | Arrival Time 01:35PM | Duration 9h30 | Departure days Fri | Cheapest price L 188 |
Operator Greyhound | Departure Time 06:05AM | Arrival Time 10:50AM | Duration 4h45 | Departure days Tue | Cheapest price L 148 |
Operator FlixBus | Departure Time 08:55AM | Arrival Time 12:35PM | Duration 3h40 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price L 179 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 01:15PM | Duration 3h45 | Departure days Tue | Cheapest price L 148 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 01:35PM | Duration 3h40 | Departure days Thu, Fri, Sat | Cheapest price L 174 |
Operator Greyhound | Departure Time 10:05AM | Arrival Time 02:50PM | Duration 4h45 | Departure days Mon, Wed, Thu | Cheapest price L 190 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 03:50PM | Duration 4h45 | Departure days Mon, Fri | Cheapest price L 167 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 05:15PM | Duration 3h45 | Departure days Thu | Cheapest price L 237 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 06:15PM | Duration 3h45 | Departure days Wed | Cheapest price L 182 |
Operator Greyhound | Departure Time 03:45PM | Arrival Time 08:10PM | Duration 4h25 | Departure days Tue | Cheapest price L 148 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 12:25AM | Duration 3h45 | Departure days Mon, Sat, Sun | Cheapest price L 219 |
The table below shows live departures for Greensboro, NC to Greenville, SC buses for today, Wednesday, November 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:55 AM Greensboro, NC | 3h40 | 12:35 PM Greenville, SC | 0 transfersDirect | |
![]() | 10:05 AM Greensboro, NC | 4h45 | 2:50 PM Greenville, SC | 0 transfersDirect | |
![]() | 2:30 PM Greensboro, NC | 3h45 | 6:15 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
South Carolina barbecue is slow-smoked pork, often chopped or pulled, and classically served with the state’s distinctive mustard-based sauce.
Shrimp and grits pairs creamy stone-ground grits with shrimp, often enriched with bacon or sausage. It is a Lowcountry staple found across Greenville.
Fried green tomatoes are tart unripe tomatoes breaded and fried. They are a beloved Southern side and common on Upstate menus.
Casual Greenville barbecue spot serving smoked meats, classic sides, and a relaxed neighborhood atmosphere.
Upscale downtown steakhouse and oyster bar with dry-aged beef, seafood, and an elegant supper-club feel.
Refined Southern restaurant known for seasonal plates, thoughtful cocktails, and a polished downtown setting.
Moderate for a U.S. city. Hotels and dining are usually cheaper than major metros, but car travel and limited transit can add to visitor costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually get 10-15%. Cafes often have tip jars; $1-2 is common for drinks.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Greenville, SC.
Find answers to the most common questions about traveling from Greensboro, NC to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

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