Travel Information
Compare bus, train, and flight for Boston, MA to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Boston, MA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €73. For those with little time consider booking a flight which can get you there in 4h 17m. The ticket price range depends on the travel mode: a bus costs an average of €73, and a train costs an average of €218.
Distance: 800 miles (1289 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€73 Average price Cheapest | €218 Average price | €101 Average price |
20h 27m Average total duration 19h 57m Onboard + 30m Additional time* | 19h 56m Average total duration 19h 26m Onboard + 30m Additional time* | 7h 17m Average total duration Fastest 4h 17m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Boston, MA to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Boston, MA to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of to find the best option for your trip from Boston, MA to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Boston, MA to Greenville, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Boston, MA to Greenville, SC.
Journey information
Overview: Bus from Boston, MA to Greenville, SC
Buses from Boston, MA to Greenville, SC run on average 4 times per day, taking around 19h 57m. Cheap bus tickets for this journey start at $91 (€73) if you book in advance.
The earliest bus runs at 01:30, the last at 23:00. The fastest bus covers the 800 miles (1289 km) distance in 21h 20m.
Distance 800 miles (1289 km) |
Average bus duration 19h 57m |
Cheapest ticket price $91 (€73) |
Buses per day 4 |
Fastest bus 21h 20m |
First bus 01:30 |
Last bus 23:00 |
Bus providers: FlixBus from Boston, MA to Greenville, SCYou can travel by bus between Boston, MA to Greenville, SC with FlixBus for as low as $91 (€73). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Boston, MA to Greenville, SC
Find answers to the most common questions about traveling from Boston, MA to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Boston, MA to Greenville, SC
More options for your journey from Boston, MA to Greenville, SC
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