The cheapest and fastest buses from Boston, MA to Greenville, SC
Cheapest price
$434
Average price
$434
Fastest journey
20 h 20 m
Average duration
20 h 20 m
Buses per day
1
Distance
1289 km
The best way to find a cheap bus ticket from Boston, MA to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to Greenville, SC will cost around $434 if you buy it on the day, but the cheapest tickets can be found for only $434.
Of the 1 buses that leave Boston, MA for Greenville, SC on Tue, Mar 24, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct buses cover the 1289 km distance in an average of 20 h 20 m but if you time it right, some buses will get you there in just 20 h 20 m .
On Tue, Mar 24 the slowest buses will take 20 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Boston, MA to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Boston, MA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $139. For those with little time consider booking a flight which can get you there in 7h 44m. The ticket price range depends on the travel mode: a bus costs an average of $139, and a train costs an average of $268.
Distance: 800 miles (1289 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$241 Average price Cheapest | $410 Average price | $392 Average price |
20h 27m Average total duration 19h 57m Onboard + 30m Additional time* | 19h 56m Average total duration 19h 26m Onboard + 30m Additional time* | 10h 44m Average total duration Fastest 7h 44m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Boston, MA to Greenville, SC bus times
The table below shows live departures for Boston, MA to Greenville, SC buses for today, Monday, March 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:05 PM Boston, MA | 22h10 | 6:15 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Boston, MA to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Mar 30
Why should you book Boston, MA to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Boston, MA to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Boston, MA to Greenville, SC.
Journey information
Overview: Bus from Boston, MA to Greenville, SC
Buses from Boston, MA to Greenville, SC run on average 4 times per day, taking around 19h 57m. Cheap bus tickets for this journey start at $139 (€112) if you book in advance.
The earliest bus runs at 01:30, the last at 23:00. The fastest bus covers the 800 miles (1289 km) distance in 21h 35m.
Distance 800 miles (1289 km) |
Average bus duration 19h 57m |
Cheapest ticket price $139 (€112) |
Buses per day 4 |
Fastest bus 21h 35m |
First bus 01:30 |
Last bus 23:00 |
Bus providers: FlixBus from Boston, MA to Greenville, SCYou can travel by bus between Boston, MA to Greenville, SC with FlixBus for as low as $139 (€112). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Boston, MA to Greenville, SC
Find answers to the most common questions about traveling from Boston, MA to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Boston, MA to Greenville, SC
More options for your journey from Boston, MA to Greenville, SC
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