- Must visit
Greenville County Museum Of Art
Major local art museum known for Southern art and a strong Andrew Wyeth collection. A top cultural stop in downtown Greenville.
Cheapest price
$172
Average price
$197
Fastest journey
20 h 20 m
Average duration
21 h 16 m
Buses per day
4
Distance
1289 km
The best way to find a cheap bus ticket from Boston, MA to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to Greenville, SC will cost around $197 if you buy it on the day, but the cheapest tickets can be found for only $172.
It's difficult to get from Boston, MA to Greenville, SC without transferring at least once.
FlixBus · FlixBus
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FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
· Omio recommends booking the bus as it is the most popular option from Boston, MA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $93. For those with little time consider booking a flight which can get you there in 6h 10m. The ticket price range depends on the travel mode: a bus costs an average of $93, and a train costs an average of $196.
Distance: 800 miles (1289 km)
Most popular Bus | Train | Flight |
|---|---|---|
$148 Average price Cheapest | $342 Average price | $308 Average price |
20h 27m Average total duration 19h 57m Onboard + 30m Additional time* | 19h 56m Average total duration 19h 26m Onboard + 30m Additional time* | 9h 10m Average total duration Fastest 6h 10m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Boston, MA to Greenville, SC:
A bus is $160 (€131) less than a flight for this route with tickets for a flight from Boston, MA to Greenville, SC costing on average $308 (€253).
A bus is $194 (€160) less than a train for this route with tickets for a train from Boston, MA to Greenville, SC costing on average $342 (€281).
Other travel options to Greenville, SC take longer:
Train takes on average 19h 26m.
Bus takes on average 19h 57m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:00AM | Arrival Time 08:35AM | Duration 21h35 | Departure days Wed | Cheapest price $257 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 08:35AM | Duration 20h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $131 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 01:15PM | Duration 22h15 | Departure days Tue, Wed | Cheapest price $170 |
Operator FlixBus | Departure Time 03:45PM | Arrival Time 01:15PM | Duration 21h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $154 |
Operator Greyhound | Departure Time 04:45PM | Arrival Time 02:35PM | Duration 21h50 | Departure days Everyday | Cheapest price $147 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 08:10PM | Duration 26h55 | Departure days Wed | Cheapest price $222 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 08:35AM | Duration 35h05 | Departure days Tue | Cheapest price $154 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 07:25PM | Duration 21h35 | Departure days Sun | Cheapest price $226 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 07:25PM | Duration 21h25 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $151 |
The table below shows live departures for Boston, MA to Greenville, SC buses for today, Wednesday, July 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 11:00 AM Boston, Bus Terminal South Station | 21h35 | 8:35 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
FlixBus · FlixBus | 3:00 PM Boston, Bus Terminal South Station | 22h15 | 1:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
· | 4:45 PM Boston, Bus Terminal South Station | 21h50 | 2:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
FlixBus+ · | 5:15 PM Boston, Bus Terminal South Station | 26h55 | 8:10 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Boston, MA to Greenville, SC run on average 4 times per day, taking around 19h 57m. Cheap bus tickets for this journey start at $93 (€77) if you book in advance.
The earliest bus runs at 01:30, the last at 22:00. The fastest bus covers the 800 miles (1289 km) distance in 20h 20m.
Distance 800 miles (1289 km) |
Average bus duration 19h 57m |
Cheapest ticket price $93 (€77) |
Buses per day 4 |
Fastest bus 20h 20m |
First bus 1:30 AM |
Last bus 10:00 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Major local art museum known for Southern art and a strong Andrew Wyeth collection. A top cultural stop in downtown Greenville.
History museum covering the Upstate region with rotating exhibitions and family-friendly displays on local culture and heritage.
Specialized museum with notable historic instruments and performance-related exhibits. A distinctive stop for music and design lovers.
The heart of downtown Greenville, lined with shops, public art, plazas, and lively pedestrian-friendly blocks.
Landscaped riverfront park with trails, gardens, overlooks, and easy access to downtown. Essential for first-time visitors.
Popular multi-use greenway for walking and cycling, connecting Greenville with nearby districts and scenic stretches.
A Lowcountry classic of creamy grits topped with shrimp, often finished with bacon, gravy, or a light sauce. It is one of the best-known regional dishes in Upstate and coastal South Carolina cooking.
Slices of unripe tomatoes coated and fried until crisp, often served with remoulade or pimento cheese. This Southern staple is common on Greenville menus and highlights classic regional comfort food.
A spread made from cheddar, pimentos, and mayonnaise, served with crackers, toast, or as a sandwich filling. It is a signature Southern snack strongly associated with South Carolina food culture.
A respected neighborhood restaurant focused on seasonal ingredients and thoughtful Southern-influenced cooking in a relaxed setting.
A long-established downtown restaurant known for refined Southern cooking, shrimp and grits, and a polished yet approachable atmosphere.
An established upscale restaurant with handmade pasta, oysters, and strong city views, suited for a more polished dinner in Greenville.
Moderate for U.S. travel. Meals and coffee are fairly priced, while hotels vary by season and events.
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Boston, MA to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

Most Boston, MA to Greenville, SC buses use the Boston, Bus Terminal South Station to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Boston, MA and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need