The cheapest and fastest buses from Florence, SC to Tampa, FL
Cheapest price
$111
Average price
$111
Fastest journey
17 h 5 m
Average duration
17 h 5 m
Buses per day
1
Distance
741 km
The best way to find a cheap bus ticket from Florence, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Tampa, FL will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $111.
Of the 1 buses that leave Florence, SC for Tampa, FL on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 741 km distance in an average of 17 h 5 m but if you time it right, some buses will get you there in just 17 h 5 m .
On Fri, Nov 07 the slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Florence, SC to Tampa, FL
Omio recommends booking the train as it is the most popular option from Florence, SC to Tampa, FL among Omio's users. If you are prioritising price take the train with prices starting from €85. For those with little time consider booking a bus which can get you there in 11h 0m. The ticket price range depends on the travel mode: a train costs an average of €85, and a bus costs an average of €85.
Distance: 460 miles (741 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€104 Average price | €102 Average price Cheapest |
11h 30m Average total duration Fastest 11h 0m Onboard + 30m Additional time* | 12h 16m Average total duration 11h 46m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Florence, SC to Tampa, FL bus times
The table below shows live departures for Florence, SC to Tampa, FL buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:10 PM Florence, SC | 34h40 | 10:50 PM Tampa, FL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Tampa, FL by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Bus from Florence, SC to Tampa, FL
Distance 460 miles (741 km) |
Average bus duration 11h 0m |
Cheapest ticket price $105 (€85) |
Buses per day 3 |
Fastest bus 16h 40m |
First bus 00:40 |
Last bus 22:35 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Florence, SC to Tampa, FL start from as low as $105 (€85) if booked well in advance.
- Standard Fares: Typically, trains cost $128 (€104) depending on the train type and class.
Bus providers: FlixBus, Southeastern Stages from Florence, SC to Tampa, FLYou can travel by bus between Florence, SC to Tampa, FL with FlixBus, Southeastern Stages for as low as $104 (€85). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Southeastern Stages
FAQs: Bus from Florence, SC to Tampa, FL
Find answers to the most common questions about traveling from Florence, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
- The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
- Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
- Ybor City, a historic district known for its vibrant nightlife and Cuban culture
- Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
- Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
- Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
- Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
- Take a boat tour of Tampa Bay for stunning views and wildlife sightings
- Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Florence, SC to Tampa, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Florence, SC to Tampa, FL
More options for your journey from Florence, SC to Tampa, FL
Here are some other resources that might have the information you need


