- Must visit
Tampa Museum of Art
Modern and classical art museum on the Riverwalk, known for its contemporary exhibitions and prominent downtown setting.
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The cheapest and fastest buses from Florence, SC to Tampa, FL
Showing times and prices for Jun 21
Cheapest price
$138
Average price
$193
Fastest journey
16 h 40 m
Average duration
20 h 17 m
Buses per day
7
Distance
741 km
Cheap tickets
The best way to find a cheap bus ticket from Florence, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Tampa, FL will cost around $193 if you buy it on the day, but the cheapest tickets can be found for only $138.
Fast buses
It's difficult to get from Florence, SC to Tampa, FL without transferring at least 2 times.
FlixBus · FlixBus+
· 5:45 AM27h30Florence, W Lucas St (TA Gas Station), SC9:15 AMTampa, USF Holly Drive (Central Plant), FL$1381One-way3 transfers- FlixBus · FlixBus · FlixBus5:45 AM16h40Florence, W Lucas St (TA Gas Station), SC10:25 PMTampa, Marion Transit Center$1381One-way2 transfers
- FlixBus · FlixBus+11:55 AM21h45Florence, S Irby St (Greyhound Bus Stop), SC9:40 AMTampa, Marion Transit Center$1811One-way2 transfers
- FlixBus · FlixBus+11:55 AM21h20Florence, S Irby St (Greyhound Bus Stop), SC9:15 AMTampa, USF Holly Drive (Central Plant), FL$1841One-way2 transfers
- · +FlixBus+4:30 PM29h55Florence, S Irby St (Greyhound Bus Stop), SC10:25 PMTampa, Marion Transit Center$1871One-way4 transfers
- FlixBus · FlixBus · FlixBus5:45 AM16h40Florence, W Lucas St (TA Gas Station), SC10:25 PMTampa, Marion Transit Center$1381One-way2 transfers
- FlixBus · FlixBus+4:10 PM20h35Florence, S Irby St (Greyhound Bus Stop), SC12:45 PMTampa, USF Holly Drive (Central Plant), FL$2601One-way2 transfers
- FlixBus · FlixBus+4:10 PM21h05Florence, S Irby St (Greyhound Bus Stop), SC1:15 PMTampa, Marion Transit Center$2611One-way2 transfers
- FlixBus · FlixBus+11:55 AM21h20Florence, S Irby St (Greyhound Bus Stop), SC9:15 AMTampa, USF Holly Drive (Central Plant), FL$1841One-way2 transfers
- FlixBus · FlixBus+11:55 AM21h45Florence, S Irby St (Greyhound Bus Stop), SC9:40 AMTampa, Marion Transit Center$1811One-way2 transfers
Travel Information
Compare train and bus for Florence, SC to Tampa, FL
Omio recommends booking the train as it is the most popular option from Florence, SC to Tampa, FL among Omio's users. If you are prioritising price take the bus with prices starting from $105. For those with little time consider booking a bus which can get you there in 11h 0m. The ticket price range depends on the travel mode: a bus costs an average of $105, and a train costs an average of $105.
Distance: 460 miles (741 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$151 Average price Cheapest | $152 Average price | $101 Average price (fuel + tolls) |
11h 30m Average total duration Fastest 11h 0m Onboard + 30m Additional time* | 12h 19m Average total duration 11h 49m Onboard + 30m Additional time* | 7h 31m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence, SC to Tampa, FL is a bus with an average price of $151 (€124).
This is compared to other travel options from Florence, SC to Tampa, FL:
A bus is $1 (€0.89) less than a train for this route with tickets for a train from Florence, SC to Tampa, FL costing on average $152 (€125).
The fastest way to travel from Florence, SC to Tampa, FL is by bus with an average journey time of 11h 0m.
Other travel options to Tampa, FL take longer:
Train takes on average 11h 49m.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Tampa, FL including taking a train and bus.
We recommend using the train as it is the most popular way to get from Florence, SC to Tampa, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Florence, SC to Tampa, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 10:25PM | Duration 16h40 | Departure days Sat, Sun | Cheapest price $138 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 02:25AM | Duration 16h40 | Departure days Fri | Cheapest price $153 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 09:15AM | Duration 21h20 | Departure days Sat, Sun | Cheapest price $149 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 01:30PM | Duration 21h35 | Departure days Mon | Cheapest price $137 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 01:15PM | Duration 21h05 | Departure days Sat, Sun | Cheapest price $212 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 09:15AM | Duration 17h00 | Departure days Tue | Cheapest price $114 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 10:25PM | Duration 29h55 | Departure days Sat, Sun | Cheapest price $147 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 10:00AM | Duration 14h00 | Departure days Wed, Thu, Fri | Cheapest price $105 |
Live departures
Florence, SC to Tampa, FL bus times
The table below shows live departures for Florence, SC to Tampa, FL buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus · FlixBus | 11:55 AM Florence, S Irby St (Greyhound Bus Stop), SC | 21h20 | 9:15 AM Tampa, USF Holly Drive (Central Plant), FL | 2 transfers | |
| +FlixBus · FlixBus | 11:55 AM Florence, S Irby St (Greyhound Bus Stop), SC | 21h45 | 9:40 AM Tampa, Marion Transit Center | 2 transfers | |
| +FlixBus · FlixBus | 4:10 PM Florence, S Irby St (Greyhound Bus Stop), SC | 20h35 | 12:45 PM Tampa, USF Holly Drive (Central Plant), FL | 2 transfers | |
| +FlixBus · FlixBus | 4:10 PM Florence, S Irby St (Greyhound Bus Stop), SC | 21h05 | 1:15 PM Tampa, Marion Transit Center | 2 transfers | |
| · +FlixBus+ | 4:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 29h55 | 10:25 PM Tampa, Marion Transit Center | 4 transfers | |
| FlixBus · FlixBus · FlixBus | 5:45 AM Florence, W Lucas St (TA Gas Station), SC | 16h40 | 10:25 PM Tampa, Marion Transit Center | 2 transfers | |
| FlixBus+ · +FlixBus | 5:45 AM Florence, W Lucas St (TA Gas Station), SC | 27h30 | 9:15 AM Tampa, USF Holly Drive (Central Plant), FL | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Tampa, FL by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 21
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Why should you book Florence, SC to Tampa, FL buses with Omio?
FlixBus operates all buses services from Florence, SC to Tampa, FL.
Omio is an official ticket reseller for all your travel options from Florence, SC to Tampa, FL.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Tampa, FL.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Tampa, FL.
Journey information
Overview: Bus from Florence, SC to Tampa, FL
USAUSA
Buses from Florence, SC to Tampa, FL run on average 4 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $105 (€86) but you can travel from only $105 (€86) by train.
The earliest bus runs at 03:18, the last at 22:35. The fastest bus covers the 460 miles (741 km) distance in 14h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $105 (€86)
Distance 460 miles (741 km) |
Average bus duration 11h 0m |
Cheapest ticket price $105 (€86) |
Buses per day 4 |
Fastest bus 14h 0m |
First bus 3:18 AM |
Last bus 10:35 PM |
Cheapest Month Aug |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $105 (€86)
Bus providers: FlixBus from Florence, SC to Tampa, FLYou can travel by bus between Florence, SC to Tampa, FL with FlixBus for as low as $105 (€86). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 0m
Cheapest Price
$105 (€86)
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Tampa
Things to do in Tampa
Discover the best of Tampa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa trip today.
- Must visit
The Dalí Museum
World-famous Salvador Dalí museum across the bay in St. Petersburg, frequently visited from Tampa for its iconic collection and architecture.
- Recommended
Henry B. Plant Museum
Historic museum inside the former Tampa Bay Hotel, showcasing Gilded Age architecture and Tampa history.
- Must visit
Tampa Riverwalk
Signature waterfront promenade linking museums, parks, and public art, and one of the city's most popular walking areas.
- Must visit
Ybor City
Historic neighborhood famous for brick streets, cigar heritage, nightlife, and distinctive cultural character.
- Must visit
Bayshore Boulevard
Scenic waterfront boulevard popular for walking, running, and skyline views along Hillsborough Bay.
Cuban Sandwich
Tampa’s signature sandwich, traditionally layered with Cuban bread, roast pork, ham, salami, Swiss cheese, pickles, and mustard, then pressed hot. The salami reflects the city’s Italian influence in Y
Deviled Crab
A classic Ybor City snack made with spiced crab meat mixed with breadcrumbs, formed into a shell-like shape, breaded, and fried. It reflects Tampa’s cigar-factory immigrant history and is one of the c
Grouper Sandwich
A Florida Gulf Coast favorite often found in Tampa, featuring fresh local grouper grilled, blackened, or fried on a bun. It is especially popular for showcasing the region’s seafood.
Bern's Steak House
Iconic fine-dining destination famous for dry-aged steaks, an extensive wine collection, and classic Tampa special-occasion dining.
Columbia Restaurant
Historic Ybor City institution known for Spanish-Cuban cuisine, the 1905 Salad, and flamenco performances in a grand old-world setting.
Ulele
Popular riverfront restaurant serving Florida-inspired dishes, charbroiled oysters, and native-inspired flavors in a lively upscale-casual atmosphere.
United States Dollar
Moderate for U.S. travelers. Dining and transport are manageable, while hotels rise in peak season and waterfront areas.
Average meal costs
- Budget
- USD 10-18 for a casual meal.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person before drinks.
- Coffee
- USD 4-6 for a coffee.
Tipping culture
Tip 18-20% at restaurants. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5. Tips are expected for table service.
FAQs: Bus from Florence, SC to Tampa, FL
Find answers to the most common questions about traveling from Florence, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Florence, SC to Tampa, FL can start from as little as $105 (€86) when you book in advance. The average bus ticket price for Florence, SC to Tampa, FL is $151 (€124) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Tampa, FL is 14h 0m to travel the 460 miles (741 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Tampa, FL leaves at 3:18 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Tampa, FL leaves at 10:35 PM.
There are 4 buses a day from Florence, SC to Tampa, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Tampa, FL, you can count on FlixBus for the best way to get you to Tampa, FL. You can also check all possible bus companies who offer a service between Florence, SC and Tampa, FL and compare the amenities they offer before buying a bus ticket.
A trip to Tampa, FL from Florence, SC is worth doing but not as a day trip with a journey time of 14h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Tampa, FL is August.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Tampa, FL including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Tampa, FL:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Tampa, FL for bus company FlixBus.
Some of the most interesting sights to explore in Tampa, FL are:
- Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
- The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
- Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
- Ybor City, a historic district known for its vibrant nightlife and Cuban culture
- Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
The best things to do in Tampa, FL include:
- Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
- Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
- Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
- Take a boat tour of Tampa Bay for stunning views and wildlife sightings
- Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
Whether you can cancel your bus ticket from Florence, SC to Tampa, FL depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Tampa, FL.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Tampa, FL:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Tampa, FL:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Tampa, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Tampa, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Tampa, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Tampa, FL with the following bus company: FlixBus.
Since neither Florence, SC nor Tampa, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Florence, SC to Tampa, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Tampa, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots like Ybor City and downtown. Common scams include overcharging by taxi or rideshare drivers and timeshare presentations that pressure visitors into costly purchases. Staying aware of surroundings and using licensed transportation can help avoid these issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Florence, SC to Tampa, FL
Florence
Tampa
The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Tampa.
Florence, S Irby St (Greyhound Bus Stop)
information
The major bus station for arrivals in Tampa is Tampa, Marion Transit Center. Find all the information you need to know about services, amenities and connections at Tampa, Marion Transit Center for your trip to Tampa from Florence.
Tampa, Marion Transit Center
information
Tampa, USF Holly Drive (Central Plant)
information
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Tampa, FL
Here are some other resources that might have the information you need
Most popular buses to and from Tampa, FL and Florence, SC
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