Florence, SC to Tampa, FL bus with FlixBus

Sat, Sep 19
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2,000+ travel companies
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The cheapest and fastest buses from Florence, SC to Tampa, FL

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

$181

Average ticket price on Sep 19

$181

Fastest journey on Sep 19

16 h 40 m

Average journey duration on Sep 19

16 h 40 m

Buses on Sep 19

1

Distance

741 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Tampa, FL will cost around $181 if you buy it on the day, but the cheapest tickets can be found for only $181.

Fast buses

On Sat, Sep 19, we found 1 buses from Florence, SC to Tampa, FL, including 1 direct services.

On Sat, Sep 19 the direct buses cover the 741 km distance in an average of 16 h 40 m but if you time it right, some buses will get you there in just 16 h 40 m .

On Sat, Sep 19 the slowest buses will take 16 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    10:45 AM16h40
    Florence, SC
    3:25 AMTampa, FL
    $1811One-way
    0 transfers

Travel Information

Compare train, bus, and flight for Florence, SC to Tampa, FL

Omio recommends booking the train as it is the most popular option from Florence, SC to Tampa, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $152 For those with little time, consider booking a flight, which has an average total journey time of 6h 24m. Average ticket prices depend on the travel mode: a bus costs an average of $152, while a flight costs an average of $696.

Distance: 460 miles (741 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$152

Average price

Cheapest

$170

Average price

$696

Average price

$102

Average price

(fuel + tolls)

15h 48m

Average total duration

15h 18m

Onboard

+

30m

Additional time*

12h 27m

Average total duration

11h 57m

Onboard

+

30m

Additional time*

6h 24m

Average total duration

Fastest

4h 24m

Onboard

+

2h 0m

Additional time*

7h 31m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

Amtrak

Most popular train company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence, SC to Tampa, FL is a bus with an average price of $152.

This is compared to other travel options from Florence, SC to Tampa, FL:

A bus is $18 less than a train for this route with tickets for a train from Florence, SC to Tampa, FL costing on average $170.

A bus is $544 less than a flight for this route with tickets for a flight from Florence, SC to Tampa, FL costing on average $696.

The fastest way to travel from Florence, SC to Tampa, FL is by flight with an average journey time of 4h 24m.

Other travel options to Tampa, FL take longer:

Train takes on average 11h 57m.

Bus takes on average 15h 18m.

It's helpful to compare your options as there are 3 ways to travel between Florence, SC and Tampa, FL including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Florence, SC to Tampa, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $152 compared to roughly $102 in fuel and tolls — a saving of about $-49.66. The journey takes 15h 18m versus 7h 31m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Florence, SC to Tampa, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
05:45AM
Arrival Time
10:25PM
Duration
16h40
Departure days
Fri
Cheapest price
$101
Operator
FlixBus
Departure Time
09:45AM
Arrival Time
02:25AM
Duration
16h40
Departure days
Sun
Cheapest price
$178
Operator
FlixBus
Departure Time
10:45AM
Arrival Time
03:25AM
Duration
16h40
Departure days
Sat, Sun
Cheapest price
$181
Operator
FlixBus
Departure Time
03:55PM
Arrival Time
01:30PM
Duration
21h35
Departure days
Mon
Cheapest price
$137
Operator
Flixbus USA
Departure Time
04:00PM
Arrival Time
06:00AM
Duration
14h00
Departure days
Tue
Cheapest price
$101
Operator
FlixBus
Departure Time
08:00PM
Arrival Time
10:00AM
Duration
14h00
Departure days
Wed, Thu
Cheapest price
$109

Live departures

Florence, SC to Tampa, FL bus times

The table below shows live departures for Florence, SC to Tampa, FL buses for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBus10:45 AM Florence, SC
16h40
3:25 AM Tampa, FL0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence, SC to Tampa, FL by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Florence, SC to Tampa, FL buses with Omio?

Greyhound as well as FlixBus offer buses services from Florence, SC to Tampa, FL.
Omio is an official ticket reseller for all your travel options from Florence, SC to Tampa, FL.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Tampa, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence, SC to Tampa, FL.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Tampa, FL.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Florence, SC to Tampa, FL.

Journey information

Overview: Bus from Florence, SC to Tampa, FL

USAUSA
USAUSA
Icon of bus

Buses from Florence, SC to Tampa, FL run on average 4 times per day, taking around 15h 18m. Cheap bus tickets for this journey start at $79 if you book in advance.

The earliest bus runs at 03:18, the last at 22:35. The fastest bus covers the 460 miles (741 km) distance in 9h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
460 miles (741 km)
Average bus duration
15h 18m
Cheapest ticket price
$79
Buses per day
4
Fastest bus
9h 20m
First bus
3:18 AM
Last bus
10:35 PM
Cheapest Month
Aug
Cheapest Day
Mon
High Season
Apr - Jun
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Florence, SC to Tampa, FLYou can travel by bus between Florence, SC to Tampa, FL with FlixBus, Greyhound for as low as $79. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 20m
Cheapest FlixBus Price
$79
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
20h 40m
Cheapest Greyhound Price
$133
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Tampa, FL

Things to do in Tampa, FL

Discover the best of Tampa, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa, FL trip today.

  • Must visit

Tampa Museum of Art

Major art museum on the Riverwalk with Greek and Roman antiquities, modern art, and a strong photography collection.

  • Must visit

Tampa Bay History Center

Engaging family-friendly museum exploring Tampa Bay history through exhibits on pirates, cigars, industry, and local communities.

  • Recommended

Henry B. Plant Museum

Fascinating history museum inside the former Tampa Bay Hotel, showcasing Gilded Age rooms, décor, and Florida tourism heritage.

United States dollar ($)

Moderate for U.S. beach cities: hotels can be high in peak season, but dining and local transport are usually manageable for most visitors.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$20-40 per person for a meal.
Fine dining
$60+ per person for upscale restaurants.
Coffee
$3-6 for coffee or cappuccino.

Tipping culture

Tip 15-20% at restaurants, 18-22% for great service. Taxis usually 10-15%. For cafes, small change or $1 per drink is common but optional.

FAQs: Bus from Florence, SC to Tampa, FL

Find answers to the most common questions about traveling from Florence, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Tampa, FL can start from as little as $79 when you book in advance. The average bus ticket price for Florence, SC to Tampa, FL is $152 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Tampa, FL is 9h 20m to travel the 460 miles (741 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Tampa, FL leaves at 3:18 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Tampa, FL leaves at 10:35 PM.
There are 4 buses a day from Florence, SC to Tampa, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Tampa, FL, you can count on Greyhound, FlixBus for the best way to get you to Tampa, FL. You can also check all possible bus companies who offer a service between Florence, SC and Tampa, FL and compare the amenities they offer before buying a bus ticket.
When departing from Florence, SC , you have various bus station options to start your journey from including Florence, W Lucas St (TA Gas Station), SC, Florence, S Irby St (Greyhound Bus Stop), SC . When arriving in Tampa, FL , you can end your journey in bus stations like Tampa, Marion Transit Center, Tampa, USF Holly Drive (Central Plant), FL .Passengers board the bus most frequently from Florence, W Lucas St (TA Gas Station), SC, which is located around 3 miles (6 km) away from the city centre, and they get off the bus at Tampa, Marion Transit Center, located 0 away from the city centre.
A trip to Tampa, FL from Florence, SC is worth doing but not as a day trip with a journey time of 9h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Tampa, FL is August.
It's helpful to compare your options as there are 3 ways to travel between Florence, SC and Tampa, FL including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Florence, SC to Tampa, FL for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Tampa, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Tampa, FL are:
  • Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
  • The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
  • Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
  • Ybor City, a historic district known for its vibrant nightlife and Cuban culture
  • Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
The best things to do in Tampa, FL include:
  • Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
  • Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
  • Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
  • Take a boat tour of Tampa Bay for stunning views and wildlife sightings
  • Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
Whether you can cancel your bus ticket from Florence, SC to Tampa, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Tampa, FL.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Tampa, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Tampa, FL:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Tampa, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Tampa, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Tampa, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Tampa, FL with the following bus company: Greyhound, FlixBus.
Since neither Florence, SC nor Tampa, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Florence, SC to Tampa, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Tampa, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots like Ybor City and downtown. Common scams include overcharging by taxi or rideshare drivers and timeshare presentations that pressure visitors into costly purchases. Staying aware of surroundings and using licensed transportation can help avoid these issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Florence, SC to Tampa, FL

Most Florence, SC to Tampa, FL buses use the Florence, W Lucas St (TA Gas Station) to Tampa, USF Holly Drive (Central Plant) station pair, with some services arriving at Tampa, Marion Transit Center. Use this guide to compare Florence, SC and Tampa, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Florence
Arrival bus stations in Tampa

Which Florence, SC station do buses to Tampa, FL leave from?

Buses from Florence, SC to Tampa, FL leave from Florence, W Lucas St (TA Gas Station). The station is 3 miles (6 km) from Florence, SC city centre at Florence, SC, USA.
Florence, W Lucas St (TA Gas Station)Florence, SC, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre

Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:

TRUE

Florence, W Lucas St (TA Gas Station) bus station facilities and services

Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Food and snacks available at the gas station.

Wi-Fi and ATMs

Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).

Tickets and information

Ticket office support is available at Florence, W Lucas St (TA Gas Station).

Parking, taxis and toilets

Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.

Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre

TRUE

Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services

Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).

Tickets and information

Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).

Parking, taxis and toilets

Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.

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