Durham, NC to Greenville, SC bus with FlixBus

Sat, Dec 13
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The cheapest and fastest buses from Durham, NC to Greenville, SC

Showing times and prices for Dec 17

Cheapest price

$49

Average price

$49

Fastest journey

5 h

Average duration

5 h

Buses per day

1

Distance

341 km

Cheap tickets

The best way to find a cheap bus ticket from Durham, NC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Durham, NC to Greenville, SC will cost around $49 if you buy it on the day, but the cheapest tickets can be found for only $49.

Fast buses

Of the 1 buses that leave Durham, NC for Greenville, SC on Wed, Dec 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Dec 17 the direct buses cover the 341 km distance in an average of 5 h but if you time it right, some buses will get you there in just 5 h .

On Wed, Dec 17 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
09:50AM5h00
Durham, NC
02:50PMGreenville, SC
$491One-way
0 transfers

Travel Information

Compare bus, train, and flight for Durham, NC to Greenville, SC

Omio recommends booking the bus as it is the most popular option from Durham, NC to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €35. For those with little time consider booking a bus which can get you there in 4h 52m. The ticket price range depends on the travel mode: a bus costs an average of €35, and a flight costs an average of €132.

Distance: 211 miles (341 km)

Compare bus with

Most popular
Bus
Train
Flight

€40

Average price

Cheapest

€64

Average price

€281

Average price

5h 22m

Average total duration

Fastest

4h 52m

Onboard

+

30m

Additional time*

11h 28m

Average total duration

10h 58m

Onboard

+

30m

Additional time*

8h 43m

Average total duration

5h 43m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Durham, NC to Greenville, SC bus times

The table below shows live departures for Durham, NC to Greenville, SC buses for today, Tuesday, December 16. You can also manually refresh the results below to see updated bus journeys.

Last updated at 12:31 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus6:50 PM Durham, NC
4h50
11:40 PM Greenville, SC0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Durham, NC to Greenville, SC by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Dec 17
Thu
Dec 18
Fri
Dec 19
Sat
Dec 20
Sun
Dec 21
Mon
Dec 22
Tue
Dec 23

Journey information

Overview: Bus from Durham, NC to Greenville, SC

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Icon of bus

Buses from Durham, NC to Greenville, SC run on average 4 times per day, taking around 4h 52m. Cheap bus tickets for this journey start at $44 (€35) if you book in advance.

There are 4 buses per day. The earliest bus runs at 03:50, the last at 22:15. The fastest bus covers the 211 miles (341 km) distance in 4h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
211 miles (341 km)
Average bus duration
4h 52m
Cheapest ticket price
$44 (€35)
Buses per day
4
Direct buses
4
Fastest bus
4h 40m
First bus
03:50
Last bus
22:15
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Durham, NC to Greenville, SCYou can travel by bus between Durham, NC to Greenville, SC with FlixBus for as low as $44 (€35). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
4h 40m
Cheapest Price
$43 (€34)
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Durham, NC to Greenville, SC

Find answers to the most common questions about traveling from Durham, NC to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Durham, NC to Greenville, SC can start from as little as $33 (€26) when you book in advance. The average bus ticket price for Durham, NC to Greenville, SC is $43 (€34); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time between Durham, NC and Greenville, SC is on average 4 h 25 min   for the 211 mile (341 km) long journey, but the time it takes to go to Greenville, SC from Durham, NC by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Durham, NC to Greenville, SC leaves at 3: 50AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Durham, NC to Greenville, SC leaves at 10: 15PM.
There are 5 buses a day from Durham, NC to Greenville, SC which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
Take the Durham, NC to Greenville, SC bus with FlixBus. However, it's always good to check out all possible bus providers for the trip from Durham, NC to Greenville, SC as there might be differences in the amenities they offer.
A trip to Greenville, SC from Durham, NC is worth doing but not as a day trip with a journey time of 4 h 25 min each way. Check with Omio app   the best way to travel.
The cheapest month for a bus from Durham, NC to Greenville, SC is January.
It's helpful to compare your options as there are 2 ways to travel between Durham, NC and Greenville, SC including taking a bus or train.
Yes, the following accessibility options are available when taking the bus from Durham, NC to Greenville, SC:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Durham, NC to Greenville, SC for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Durham, NC to Greenville, SC depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Durham, NC to Greenville, SC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Durham, NC to Greenville, SC.
    Yes, the following luggage options are included when booking a bus ticket from Durham, NC to Greenville, SC:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Durham, NC to Greenville, SC:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Durham, NC to Greenville, SC. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Durham, NC to Greenville, SC with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Durham, NC to Greenville, SC with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Durham, NC to Greenville, SC with the following bus company: FlixBus.

    popular bus stations

    Popular bus stations from Durham, NC to Greenville, SC

    Durham
    Greenville
    The major bus station for departures in Durham is Durham, W Pettigrew St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Durham, W Pettigrew St (Greyhound Bus Station) for your trip from Durham to Greenville.
    Durham, W Pettigrew St (Greyhound Bus Station)
    information
    address
    Address
    Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701

    More options for your journey from Durham, NC to Greenville, SC

    Here are some other resources that might have the information you need

    Return journeys for buses from Greenville, SC to Durham, NC
    Trains from Durham, NC to Greenville, SC
    Tickets and more information for coaches to Durham, NC
    Tickets and more information for coaches to Greenville, SC

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