The cheapest and fastest buses from Philadelphia, PA to Greenville, SC
Cheapest price
$95
Average price
$119
Fastest journey
14 h 5 m
Average duration
15 h 38 m
Buses per day
9
Distance
854 km
The best way to find a cheap bus ticket from Philadelphia, PA to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Greenville, SC will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $95.
Of the 9 buses that leave Philadelphia, PA for Greenville, SC on Fri, May 08, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 08 the direct buses cover the 854 km distance in an average of 15 h 38 m but if you time it right, some buses will get you there in just 14 h 5 m .
On Fri, May 08 the slowest buses will take 17 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5:50 PM17h00Philadelphia Bus Station10:50 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$951One-way0 transfers
FlixBus · FlixBus10:00 PM15h15Philadelphia Bus Station1:15 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1161One-way1 transfer
FlixBus · FlixBus6:30 PM14h05Philadelphia Bus Station8:35 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1161One-way1 transfer
undefined · undefined8:10 PM18h25Philadelphia, Schuylkill Ave (Cira Centre South), PA2:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1211One-way1 transfer
FlixBus · FlixBus6:45 PM18h30Philadelphia, Schuylkill Ave (Cira Centre South), PA1:15 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1211One-way1 transfer
FlixBus · FlixBus6:30 PM14h05Philadelphia Bus Station8:35 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1161One-way1 transfer
FlixBus · FlixBus5:00 AM14h25Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA7:25 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way1 transfer
FlixBus · FlixBus10:00 PM15h15Philadelphia Bus Station1:15 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1161One-way1 transfer
5:50 PM17h00Philadelphia Bus Station10:50 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$951One-way0 transfers
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FlixBus2:00 AM17h25Philadelphia, Schuylkill Ave (Cira Centre South), PA7:25 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$1231One-way1 transfer
Travel Information
Compare bus, flight, and train for Philadelphia, PA to Greenville, SC
Omio recommends booking the train as it is the most popular option from Philadelphia, PA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $97. For those with little time consider booking a flight which can get you there in 6h 17m. The ticket price range depends on the travel mode: a bus costs an average of $97, and a flight costs an average of $181.
Distance: 530 miles (854 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$127 Average price Cheapest | $246 Average price | $417 Average price |
13h 13m Average total duration 12h 43m Onboard + 30m Additional time* | 14h 6m Average total duration 13h 36m Onboard + 30m Additional time* | 9h 17m Average total duration Fastest 6h 17m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Philadelphia, PA to Greenville, SC:
A bus is $118 (€95) less than a train for this route with tickets for a train from Philadelphia, PA to Greenville, SC costing on average $246 (€196).
A bus is $289 (€231) less than a flight for this route with tickets for a flight from Philadelphia, PA to Greenville, SC costing on average $417 (€333).
Other travel options to Greenville, SC take longer:
Bus takes on average 12h 43m.
Train takes on average 13h 36m.
Philadelphia, PA to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:50AM | Arrival Time 07:25PM | Duration 17h35 | Departure days Fri | Cheapest price $123 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 07:25PM | Duration 17h25 | Departure days Fri | Cheapest price $123 |
Operator FlixBus | Departure Time 05:00AM | Arrival Time 07:25PM | Duration 14h25 | Departure days Fri | Cheapest price $123 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 08:35AM | Duration 18h20 | Departure days Fri | Cheapest price $130 |
Operator Greyhound | Departure Time 05:50PM | Arrival Time 10:50AM | Duration 17h00 | Departure days Fri | Cheapest price $95 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 08:35AM | Duration 14h05 | Departure days Fri | Cheapest price $116 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 01:15PM | Duration 18h30 | Departure days Fri | Cheapest price $121 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 02:35PM | Duration 18h25 | Departure days Fri | Cheapest price $121 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 01:15PM | Duration 15h15 | Departure days Fri | Cheapest price $116 |
Live departures
Philadelphia, PA to Greenville, SC bus times
The table below shows live departures for Philadelphia, PA to Greenville, SC buses for today, Thursday, May 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:25 PM Philadelphia, PA | 19h10 | 1:35 PM Greenville, SC | 0 transfersDirect | |
![]() | 10:50 PM Philadelphia, PA | 17h00 | 3:50 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Philadelphia, PA to Greenville, SC by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 14
Why should you book Philadelphia, PA to Greenville, SC buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Philadelphia, PA to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Philadelphia, PA to Greenville, SC.
Journey information
Overview: Bus from Philadelphia, PA to Greenville, SC
Buses from Philadelphia, PA to Greenville, SC run on average 11 times per day, taking around 12h 43m. Cheap bus tickets for this journey start at $97 (€77) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 530 miles (854 km) distance in 16h 20m.
Distance 530 miles (854 km) |
Average bus duration 12h 43m |
Cheapest ticket price $97 (€77) |
Buses per day 11 |
Direct buses 1 |
Fastest bus 16h 20m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 28 days |
Bus providers: FlixBus from Philadelphia, PA to Greenville, SCYou can travel by bus between Philadelphia, PA to Greenville, SC with FlixBus for as low as $97 (€77). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Philadelphia, PA to Greenville, SC
Find answers to the most common questions about traveling from Philadelphia, PA to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Philadelphia, PA to Greenville, SC
Most popular bus connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to Greenville, SC
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