The cheapest and fastest buses from New Orleans, LA to Greenville, SC
Cheapest price
$162
Average price
$162
Fastest journey
12 h 50 m
Average duration
12 h 50 m
Buses per day
1
Distance
903 km
The best way to find a cheap bus ticket from New Orleans, LA to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from New Orleans, LA to Greenville, SC will cost around $162 if you buy it on the day, but the cheapest tickets can be found for only $162.
Of the 1 buses that leave New Orleans, LA for Greenville, SC on Thu, May 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 21 the direct buses cover the 903 km distance in an average of 12 h 50 m but if you time it right, some buses will get you there in just 12 h 50 m .
On Thu, May 21 the slowest buses will take 12 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:50 AM12h50New Orleans, LA2:40 PMGreenville, SC$1621One-way0 transfers
1:50 AM12h50New Orleans, LA2:40 PMGreenville, SC$1621One-way0 transfers
Travel Information
Compare bus, train, and flight for New Orleans, LA to Greenville, SC
Omio recommends booking the train as it is the most popular option from New Orleans, LA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $117. For those with little time consider booking a flight which can get you there in 7h 16m. The ticket price range depends on the travel mode: a bus costs an average of $117, and a flight costs an average of $177.
Distance: 561 miles (903 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$141 Average price Cheapest | $193 Average price | $315 Average price |
11h 30m Average total duration 11h 0m Onboard + 30m Additional time* | 16h 45m Average total duration 16h 15m Onboard + 30m Additional time* | 10h 16m Average total duration Fastest 7h 16m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from New Orleans, LA to Greenville, SC:
A bus is $52 (€42) less than a train for this route with tickets for a train from New Orleans, LA to Greenville, SC costing on average $193 (€156).
A bus is $174 (€141) less than a flight for this route with tickets for a flight from New Orleans, LA to Greenville, SC costing on average $315 (€255).
Other travel options to Greenville, SC take longer:
Bus takes on average 11h 0m.
Train takes on average 16h 15m.
New Orleans, LA to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:50AM | Arrival Time 02:40PM | Duration 12h50 | Departure days Mon, Tue, Thu, Sat | Cheapest price $128 |
Operator Greyhound | Departure Time 02:10AM | Arrival Time 02:40PM | Duration 12h30 | Departure days Tue | Cheapest price $117 |
Operator Greyhound | Departure Time 04:15AM | Arrival Time 01:55AM | Duration 21h40 | Departure days Mon | Cheapest price $129 |
Operator Greyhound | Departure Time 06:15PM | Arrival Time 11:00AM | Duration 16h45 | Departure days Thu, Sat | Cheapest price $121 |
Live departures
New Orleans, LA to Greenville, SC bus times
The table below shows live departures for New Orleans, LA to Greenville, SC buses for tomorrow, Wednesday, May 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:50 AM New Orleans, LA | 12h50 | 2:40 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets New Orleans, LA to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 20
May 21
May 22
May 23
May 24
May 25
May 26
Why should you book New Orleans, LA to Greenville, SC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from New Orleans, LA to Greenville, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from New Orleans, LA to Greenville, SC.
Journey information
Overview: Bus from New Orleans, LA to Greenville, SC
Buses from New Orleans, LA to Greenville, SC run on average 3 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $117 (€94) if you book in advance.
The earliest bus runs at 05:10, the last at 23:35. The fastest bus covers the 561 miles (903 km) distance in 12h 30m.
Distance 561 miles (903 km) |
Average bus duration 11h 0m |
Cheapest ticket price $117 (€94) |
Buses per day 3 |
Fastest bus 12h 30m |
First bus 5:10 AM |
Last bus 11:35 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 28 days |
Bus providers: Greyhound from New Orleans, LA to Greenville, SCYou can travel by bus between New Orleans, LA to Greenville, SC with Greyhound for as low as $117 (€94). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from New Orleans, LA to Greenville, SC
Find answers to the most common questions about traveling from New Orleans, LA to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from New Orleans, LA to Greenville, SC
More options for your journey from New Orleans, LA to Greenville, SC
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