- Must visit
Greenville County Museum Of Art
Major local art museum known for Southern art and a strong Andrew Wyeth collection. A top cultural stop in downtown Greenville.
Cheapest price
$100
Average price
$106
Fastest journey
12 h 50 m
Average duration
12 h 50 m
Buses per day
2
Distance
903 km
The best way to find a cheap bus ticket from New Orleans, LA to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from New Orleans, LA to Greenville, SC will cost around $106 if you buy it on the day, but the cheapest tickets can be found for only $100.
It's difficult to get from New Orleans, LA to Greenville, SC without transferring at least once.
·
·
·
· Omio recommends booking the train as it is the most popular option from New Orleans, LA to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $115. For those with little time consider booking a flight which can get you there in 7h 16m. The ticket price range depends on the travel mode: a bus costs an average of $115, and a flight costs an average of $174.
Distance: 561 miles (903 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$138 Average price Cheapest | $189 Average price | $309 Average price |
11h 30m Average total duration 11h 0m Onboard + 30m Additional time* | 16h 45m Average total duration 16h 15m Onboard + 30m Additional time* | 10h 16m Average total duration Fastest 7h 16m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from New Orleans, LA to Greenville, SC:
A bus is $51 (€42) less than a train for this route with tickets for a train from New Orleans, LA to Greenville, SC costing on average $189 (€156).
A bus is $171 (€141) less than a flight for this route with tickets for a flight from New Orleans, LA to Greenville, SC costing on average $309 (€255).
Other travel options to Greenville, SC take longer:
Bus takes on average 11h 0m.
Train takes on average 16h 15m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:25PM | Arrival Time 03:15AM | Duration 12h50 | Departure days Everyday | Cheapest price $99 |
Operator Greyhound | Departure Time 08:50PM | Arrival Time 10:40AM | Duration 12h50 | Departure days Everyday | Cheapest price $97 |
The table below shows live departures for New Orleans, LA to Greenville, SC buses for today, Wednesday, July 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 1:25 PM New Orleans, LA | 12h50 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from New Orleans, LA to Greenville, SC run on average 3 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $115 (€94) if you book in advance.
The earliest bus runs at 05:10, the last at 23:35. The fastest bus covers the 561 miles (903 km) distance in 12h 30m.
Distance 561 miles (903 km) |
Average bus duration 11h 0m |
Cheapest ticket price $115 (€94) |
Buses per day 3 |
Fastest bus 12h 30m |
First bus 5:10 AM |
Last bus 11:35 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 28 days |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Major local art museum known for Southern art and a strong Andrew Wyeth collection. A top cultural stop in downtown Greenville.
History museum covering the Upstate region with rotating exhibitions and family-friendly displays on local culture and heritage.
Specialized museum with notable historic instruments and performance-related exhibits. A distinctive stop for music and design lovers.
The heart of downtown Greenville, lined with shops, public art, plazas, and lively pedestrian-friendly blocks.
Landscaped riverfront park with trails, gardens, overlooks, and easy access to downtown. Essential for first-time visitors.
Popular multi-use greenway for walking and cycling, connecting Greenville with nearby districts and scenic stretches.
A Lowcountry classic of creamy grits topped with shrimp, often finished with bacon, gravy, or a light sauce. It is one of the best-known regional dishes in Upstate and coastal South Carolina cooking.
Slices of unripe tomatoes coated and fried until crisp, often served with remoulade or pimento cheese. This Southern staple is common on Greenville menus and highlights classic regional comfort food.
A spread made from cheddar, pimentos, and mayonnaise, served with crackers, toast, or as a sandwich filling. It is a signature Southern snack strongly associated with South Carolina food culture.
A respected neighborhood restaurant focused on seasonal ingredients and thoughtful Southern-influenced cooking in a relaxed setting.
A long-established downtown restaurant known for refined Southern cooking, shrimp and grits, and a polished yet approachable atmosphere.
An established upscale restaurant with handmade pasta, oysters, and strong city views, suited for a more polished dinner in Greenville.
Moderate for U.S. travel. Meals and coffee are fairly priced, while hotels vary by season and events.
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from New Orleans, LA to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

Most New Orleans, LA to Greenville, SC buses use the New Orleans, LA to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare New Orleans, LA and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need