- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
More than 1,000 travel companies trust us to sell their tickets all in one place.
Popular departures
Bus tickets to Florence, SC
Select departure
Showing the fastest and cheapest results for Oct 10
Results include alternative arrival locations to Florence, SC
9:30 PM13h15New York, NY10:45 AMFlorence, SC$1241One-way0 transfers- 8:30 PM13h15New York, NY9:45 AMFlorence, SC$1681One-way0 transfers
- 11:00 PM16h45New York, NY3:45 PMFlorence, SC$2111One-way0 transfers
Popular buses to and from Florence, SC
Popular buses to Florence, SC
Charlotte, NC to Florence, SC bus
from $22
Direct buses available
2h15 average duration
1bus per day
Served by
- FlixBus
- Greyhound
Savannah, GA to Florence, SC bus
from $32
Direct buses available
2h50 average duration
1bus per day
Served by
- FlixBus
Richmond, VA to Florence, SC bus
from $40
Direct buses available
5h35 average duration
2buses per day
Served by
- FlixBus
- Greyhound
Popular buses from Florence, SC
Florence, SC to Bluefield, WV bus
Direct buses available
Florence, SC to Atlanta, GA bus
from $50
Direct buses available
6h40 average duration
2buses per day
Served by
- Greyhound
- FlixBus
Florence, SC to New York, NY bus
from $87
Direct buses available
12h10 average duration
3buses per day
Served by
- Greyhound
- FlixBus
Florence, SC to Chicago, IL bus
from $115
Direct buses available
23h15 average duration
3buses per day
Served by
- Greyhound
- FlixBus
Florence, SC to Minneapolis, MN bus
from $243
Direct buses available
8h50 average duration
3buses per day
Served by
- Greyhound
Bus providers: FlixBus, Greyhound to BerlinTravel to Florence, SC on FlixBus, Greyhound buses with Omio. When comparing schedules and tickets, we will also show you other options with multiple connections or other travel modes if they’re available.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
12h 25m
Cheapest FlixBus Price
$88
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
12h 0m
Cheapest Greyhound Price
$96
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Florence, SC
Things to do in Florence, SC
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
- Must visit
Galleria dell'Accademia
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
- Recommended
Museo dell'Opera del Duomo
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
- Must visit
Piazza della Signoria
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
- Must visit
Piazzale Michelangelo
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
- Recommended
Boboli Gardens
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
- Gluten-free
Pee Dee Pulled Pork BBQ
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
- Gluten-free
Smoked Pork Ribs
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
- Gluten-free
Shrimp and Grits
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Victors
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Wholly Smokin' Downtown
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Holt Bros BBQ
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
$ US Dollar
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Average meal costs
- Budget
- $8-12 for fast food or casual takeout.
- Mid-range
- $15-25 per person for a casual sit-down meal.
- Fine dining
- $35+ per person for upscale restaurants.
- Coffee
- $3-5 for regular coffee or latte.
Tipping culture
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
Buses to Florence, SC: related information
Here are some other resources that might have the information you need
Buses from Florence, SC
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
