The cheapest and fastest buses from Baltimore, MD to Greenville, SC
Cheapest price
$75
Average price
$75
Fastest journey
12 h 30 m
Average duration
12 h 30 m
Buses per day
1
Distance
711 km
The best way to find a cheap bus ticket from Baltimore, MD to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Baltimore, MD to Greenville, SC will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $75.
Of the 1 buses that leave Baltimore, MD for Greenville, SC on Mon, Dec 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct buses cover the 711 km distance in an average of 12 h 30 m but if you time it right, some buses will get you there in just 12 h 30 m .
On Mon, Dec 22 the slowest buses will take 12 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Live departures
Baltimore, MD to Greenville, SC bus times
The table below shows live departures for Baltimore, MD to Greenville, SC buses for tomorrow, Monday, December 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:05 AM Baltimore, MD | 12h30 | 6:35 PM Greenville, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Compare prices and tickets Baltimore, MD to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Baltimore, MD to Greenville, SC
Take a bus from Baltimore, MD to Greenville, SC and enjoy the approximately 441 miles (711 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 4 buses per day. The earliest bus runs at 01:10, the last at 23:45.
Distance 441 miles (711 km) |
Average bus duration 12h 48m |
Buses per day 7 |
Direct buses 4 |
First bus 01:10 |
Last bus 23:45 |
Bus providers: Greyhound, FlixBus from Baltimore, MD to Greenville, SCYou can travel by bus between Baltimore, MD to Greenville, SC with Greyhound, FlixBus. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Baltimore, MD to Greenville, SC
Find answers to the most common questions about traveling from Baltimore, MD to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Baltimore, MD to Greenville, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
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Popular bus stations from Baltimore, MD to Greenville, SC
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