- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Cheapest price
$82
Average price
$101
Fastest journey
10 h 55 m
Average duration
12 h 25 m
Buses per day
2
Distance
711 km
The best way to find a cheap bus ticket from Baltimore, MD to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Baltimore, MD to Greenville, SC will cost around $101 if you buy it on the day, but the cheapest tickets can be found for only $82.
Of the 2 buses that leave Baltimore, MD for Greenville, SC on Sat, Jun 27, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 27 the direct buses cover the 711 km distance in an average of 12 h 25 m but if you time it right, some buses will get you there in just 10 h 55 m .
On Sat, Jun 27 the slowest buses will take 13 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Baltimore, MD to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $82. For those with little time consider booking a flight which can get you there in 4h 6m. The ticket price range depends on the travel mode: a bus costs an average of $82, and a flight costs an average of $197.
Distance: 441 miles (711 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$93 Average price Cheapest | $196 Average price | $242 Average price | $104 Average price (fuel + tolls) |
13h 9m Average total duration 12h 39m Onboard + 30m Additional time* | 12h 50m Average total duration 12h 20m Onboard + 30m Additional time* | 7h 6m Average total duration Fastest 4h 6m Onboard + 3h 0m Additional time* | 8h 13m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Baltimore, MD to Greenville, SC:
A bus is $103 (€84) less than a train for this route with tickets for a train from Baltimore, MD to Greenville, SC costing on average $196 (€160).
A bus is $149 (€122) less than a flight for this route with tickets for a flight from Baltimore, MD to Greenville, SC costing on average $242 (€198).
Other travel options to Greenville, SC take longer:
Train takes on average 12h 20m.
Bus takes on average 12h 39m.
Tickets start at around $93 (€76) compared to roughly $104 (€85) in fuel and tolls — a saving of about $11 (€9). The journey takes 12h 39m versus 8h 13m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:35AM | Arrival Time 01:15PM | Duration 11h40 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $79 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 12:35PM | Duration 10h55 | Departure days Mon | Cheapest price $121 |
Operator Greyhound | Departure Time 01:55AM | Arrival Time 03:50PM | Duration 13h55 | Departure days Mon | Cheapest price $82 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 08:10PM | Duration 14h20 | Departure days Wed, Thu | Cheapest price $87 |
Operator FlixBus | Departure Time 06:55AM | Arrival Time 07:25PM | Duration 12h30 | Departure days Tue, Fri, Sat | Cheapest price $82 |
Operator Greyhound | Departure Time 08:55PM | Arrival Time 10:50AM | Duration 13h55 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $75 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 08:35AM | Duration 10h55 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $66 |
Operator FlixBus | Departure Time 11:25PM | Arrival Time 01:15PM | Duration 13h50 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $100 |
The table below shows live departures for Baltimore, MD to Greenville, SC buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 6:55 AM Baltimore, Haines St (Baltimore Downtown Bus Station) | 12h30 | 7:25 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
![]() | 8:55 PM Baltimore, Haines St (Baltimore Downtown Bus Station) | 13h55 | 10:50 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 0 transfersDirect | |
FlixBus | 9:40 PM Baltimore, Haines St (Baltimore Downtown Bus Station) | 10h55 | 8:35 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 0 transfersDirect | |
| Sunday, June 21 | |||||
![]() | 1:40 AM Baltimore, MD | 10h55 | 12:35 PM Greenville, SC | 0 transfersDirect | |
![]() | 1:55 AM Baltimore, MD | 13h55 | 3:50 PM Greenville, SC | 0 transfersDirect | |
FlixBus · FlixBus | 11:25 PM Baltimore, Haines St (Baltimore Downtown Bus Station) | 13h50 | 1:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Baltimore, MD to Greenville, SC run on average 6 times per day, taking around 12h 39m. Cheap bus tickets for this journey start at $82 (€67) if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:35, the last at 23:45. The fastest bus covers the 441 miles (711 km) distance in 10h 55m.
Distance 441 miles (711 km) |
Average bus duration 12h 39m |
Cheapest ticket price $82 (€67) |
Buses per day 6 |
Direct buses 3 |
Fastest bus 10h 55m |
First bus 1:35 AM |
Last bus 11:45 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Baltimore, MD to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

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