The cheapest and fastest buses from Florence, SC to Baltimore, MD
Cheapest price
$123
Average price
$123
Fastest journey
11 h 5 m
Average duration
11 h 5 m
Buses per day
1
Distance
632 km
The best way to find a cheap bus ticket from Florence, SC to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Baltimore, MD will cost around $123 if you buy it on the day, but the cheapest tickets can be found for only $123.
Of the 1 buses that leave Florence, SC for Baltimore, MD on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 632 km distance in an average of 11 h 5 m but if you time it right, some buses will get you there in just 11 h 5 m .
On Sun, Mar 22 the slowest buses will take 11 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Florence, SC to Baltimore, MD
Omio recommends booking the train as it is the most popular option from Florence, SC to Baltimore, MD among Omio's users. If you are prioritising price take the bus with prices starting from $102. For those with little time consider booking a bus which can get you there in 9h 0m. The ticket price range depends on the travel mode: a bus costs an average of $102, and a train costs an average of $88.
Distance: 392 miles (632 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$131 Average price Cheapest | $154 Average price |
9h 30m Average total duration Fastest 9h 0m Onboard + 30m Additional time* | 10h 1m Average total duration 9h 31m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Florence, SC to Baltimore, MD Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 09:25AM | Duration 9h20 | Departure days Sat | Cheapest price $129 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 03:35AM | Duration 11h05 | Departure days Sat | Cheapest price $162 |
Live departures
Florence, SC to Baltimore, MD bus times
The table below shows live departures for Florence, SC to Baltimore, MD buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined · undefined | 8:30 PM Florence, S Irby St (Greyhound Bus Stop), SC | 11h05 | 7:35 AM Baltimore, Haines St (Baltimore Downtown Bus Station) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Baltimore, MD by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Florence, SC to Baltimore, MD buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Southeastern Stages to find the best option for your trip from Florence, SC to Baltimore, MD.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Baltimore, MD.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Baltimore, MD.
Journey information
Overview: Bus from Florence, SC to Baltimore, MD
Buses from Florence, SC to Baltimore, MD run on average 2 times per day, taking around 9h 0m. Cheap bus tickets for this journey start at $102 (€83) but you can travel from only $88 (€72) by train.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 392 miles (632 km) distance in 11h 5m.
Distance 392 miles (632 km) |
Average bus duration 9h 0m |
Cheapest ticket price $102 (€83) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 11h 5m |
First bus 00:05 |
Last bus 23:45 |
Bus providers: FlixBus, Southeastern Stages from Florence, SC to Baltimore, MDYou can travel by bus between Florence, SC to Baltimore, MD with FlixBus, Southeastern Stages for as low as $88 (€72). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Southeastern Stages
FAQs: Bus from Florence, SC to Baltimore, MD
Find answers to the most common questions about traveling from Florence, SC to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Fort McHenry National Monument, a historic site known for its role in the War of 1812 and birthplace of the U.S. national anthem
- National Aquarium, a renowned facility featuring diverse marine life exhibits and conservation programs
- Baltimore Museum of Art, home to an extensive collection of 19th-century, modern, and contemporary art
- Inner Harbor, a vibrant waterfront area with shops, restaurants, and attractions like the Maryland Science Center
- American Visionary Art Museum, showcasing unique and innovative works by self-taught artists.
- Walk through Fell's Point, a charming historic district with cobblestone streets, pubs, and boutiques
- Enjoy a scenic stroll through Patterson Park, a large urban park offering beautiful views, walking trails, and a historic pagoda
- Attend a performance at the Hippodrome Theatre, a beautifully restored venue hosting Broadway shows and concerts
- Visit the Maryland Zoo, home to a wide variety of animals and engaging exhibits
- Explore the Walters Art Museum, featuring a diverse collection of art from around the world.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Florence, SC to Baltimore, MD
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Baltimore, MD
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