The cheapest and fastest buses from Florence, SC to Baltimore, MD
Cheapest price
$119
Average price
$119
Fastest journey
9 h 20 m
Average duration
9 h 20 m
Buses per day
1
Distance
632 km
The best way to find a cheap bus ticket from Florence, SC to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Baltimore, MD will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $119.
Of the 1 buses that leave Florence, SC for Baltimore, MD on Sun, Dec 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 632 km distance in an average of 9 h 20 m but if you time it right, some buses will get you there in just 9 h 20 m .
On Sun, Dec 21 the slowest buses will take 9 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Florence, SC to Baltimore, MD
Omio recommends booking the train as it is the most popular option from Florence, SC to Baltimore, MD among Omio's users. If you are prioritising price take the bus with prices starting from €49. For those with little time consider booking a bus which can get you there in 9h 0m. The ticket price range depends on the travel mode: a bus costs an average of €49, and a train costs an average of €72.
Distance: 392 miles (632 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€76 Average price Cheapest | €99 Average price |
9h 30m Average total duration Fastest 9h 0m Onboard + 30m Additional time* | 9h 53m Average total duration 9h 23m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Florence, SC to Baltimore, MD bus times
The table below shows live departures for Florence, SC to Baltimore, MD buses for tomorrow, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:05 AM Florence, SC | 9h20 | 1:25 PM Baltimore, MD | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Baltimore, MD by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Journey information
Overview: Bus from Florence, SC to Baltimore, MD
Buses from Florence, SC to Baltimore, MD run on average 2 times per day, taking around 9h 0m. Cheap bus tickets for this journey start at $62 (€49) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 392 miles (632 km) distance in 9h 20m.
Distance 392 miles (632 km) |
Average bus duration 9h 0m |
Cheapest ticket price $62 (€49) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 9h 20m |
First bus 00:05 |
Last bus 23:45 |
Bus providers: FlixBus, Southeastern Stages from Florence, SC to Baltimore, MDYou can travel by bus between Florence, SC to Baltimore, MD with FlixBus, Southeastern Stages for as low as $62 (€49). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Southeastern Stages
FAQs: Bus from Florence, SC to Baltimore, MD
Find answers to the most common questions about traveling from Florence, SC to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Fort McHenry National Monument, a historic site known for its role in the War of 1812 and birthplace of the U. S. National anthem
- National Aquarium, a renowned facility featuring diverse marine life exhibits and conservation programs
- Baltimore Museum of Art, home to an extensive collection of 19th-century, modern, and contemporary art
- Inner Harbor, a vibrant waterfront area with shops, restaurants, and attractions like the Maryland Science Center
- American Visionary Art Museum, showcasing unique and innovative works by self-taught artists.
- Walk through Fell's Point, a charming historic district with cobblestone streets, pubs, and boutiques
- Enjoy a scenic stroll through Patterson Park, a large urban park offering beautiful views, walking trails, and a historic pagoda
- Attend a performance at the Hippodrome Theatre, a beautifully restored venue hosting Broadway shows and concerts
- Visit the Maryland Zoo, home to a wide variety of animals and engaging exhibits
- Explore the Walters Art Museum, featuring a diverse collection of art from around the world.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Florence, SC to Baltimore, MD, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Florence, SC to Baltimore, MD
More options for your journey from Florence, SC to Baltimore, MD
Here are some other resources that might have the information you need

