- Must visit
Muhammad Ali Center
Museum and archive exploring Muhammad Ali's life, boxing career, and humanitarian legacy through immersive exhibits.
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The cheapest and fastest buses from Florence, SC to Louisville, KY
Showing times, prices and bookable tickets for Nov 01
- Cheapest price on Nov 01
- €112
- Average ticket price on Nov 01
- €112
- Fastest journey on Nov 01
- 16 h 45 m
- Average journey duration on Nov 01
- 16 h 45 m
- Buses on Nov 01
- 1
- Distance
- 702 km
Cheap tickets
The best way to find a cheap bus ticket from Florence, SC to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Louisville, KY will cost around €112 if you buy it on the day, but the cheapest tickets can be found for only €112.
Fast buses
On Sun, Nov 01, we found 1 buses from Florence, SC to Louisville, KY, including 1 direct services.
On Sun, Nov 01 the direct buses cover the 702 km distance in an average of 16 h 45 m but if you time it right, some buses will get you there in just 16 h 45 m .
On Sun, Nov 01 the slowest buses will take 16 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:55 PM 16h45 Florence, SC 9:40 AM Louisville, KY €112 1 One-way 0 transfers
4:55 PM 16h45 Florence, SC 9:40 AM Louisville, KY €112 1 One-way 0 transfers
Journey information
Overview: Bus from Florence, SC to Louisville, KY
USAUSA
Buses from Florence, SC to Louisville, KY run on average 1 times per day, taking around 16h 30m. Cheap bus tickets for this journey start at €60 if you book in advance.
The earliest bus runs at 01:35, the last at 22:55. The fastest bus covers the 436 miles (702 km) distance in 16h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance436 miles (702 km)
- Average bus duration16h 30m
- Cheapest ticket price€60
- Buses per day1
- Fastest bus16h 30m
- First bus1:35 AM
- Last bus10:55 PM
- Cheapest MonthSep
- Cheapest DayTue
- High SeasonJul - Sep
- Low SeasonApr - Jun
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Florence, SC to Louisville, KY trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Florence, SC to Louisville, KY.
Cheap bus tickets from Florence, SC to Louisville, KY can start from as little as €60 when you book in advance. The average bus ticket price for Florence, SC to Louisville, KY is €82 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Florence, SC to Louisville, KY leaves at 1:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Louisville, KY leaves at 10:55 PM.
There are 1 buses a day from Florence, SC to Louisville, KY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Florence, SC to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 04:10PM | Arrival Time 08:00AM | Duration 15h50 | Departure days Tue, Wed, Thu | Cheapest price €145 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 09:40AM | Duration 16h45 | Departure days Sun | Cheapest price €112 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 01:35PM | Duration 17h25 | Departure days Mon, Fri | Cheapest price €148 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 11:20PM | Duration 26h50 | Departure days Fri | Cheapest price €137 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 12:20AM | Duration 26h50 | Departure days Fri | Cheapest price €185 |
Why should you book Florence, SC to Louisville, KY buses with Omio?
Greyhound operates all buses services from Florence, SC to Louisville, KY.
Omio is an official ticket reseller for all your travel options from Florence, SC to Louisville, KY.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Bus companies
Bus companies from Florence, SC to Louisville, KY
Buses from Florence, SC to Louisville, KY with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
16h 30m
Cheapest Greyhound Price
€60
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Florence, SC and Louisville, KY
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Florence, SC to Louisville, KY, you can count on Greyhound for the best way to get you to Louisville, KY. You can also check all possible bus companies who offer a service between Florence, SC and Louisville, KY and compare the amenities they offer before buying a bus ticket.
Yes, there are bathrooms on board the bus from Florence, SC to Louisville, KY for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Louisville, KY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Whether you can cancel your bus ticket from Florence, SC to Louisville, KY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, there is food available to purchase on board the bus from Florence, SC to Louisville, KY.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Louisville, KY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Louisville, KY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Florence, SC to Louisville, KY.
You can reserve your seat on the bus from Florence, SC to Louisville, KY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Florence, SC to Louisville, KY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Florence, SC to Louisville, KY with the following bus company: Greyhound.
Complete guide to Louisville, KY
Things to do in Louisville, KY
Discover the best of Louisville, KY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Louisville, KY trip today.
- Must visit
Kentucky Derby Museum
Interactive museum at Churchill Downs covering racing history, Kentucky Derby traditions, and access to select track areas.
- Must visit
Speed Art Museum
Regional art museum in the Speed family mansion area with global collections, modern works, and a sculpture garden.
- Must visit
Waterfront Park
Revitalized riverfront park with lawns, play areas, public art, and easy access to downtown trails and the Big Four Bridge.
- Must visit
Old Louisville
Historic district known for dense Victorian architecture, local shops, and pleasant walking streets near Central Park.
- Recommended
Cherokee Park
Olmsted-designed urban park with scenic loops, woodlands, picnic areas, and a popular walking route around the reservoir.
Hot Brown
Hot Brown is an open-faced turkey sandwich with bacon, tomato, and Mornay sauce, created at Louisville's Brown Hotel and closely tied to the city's dining history.
- Vegetarian
Benedictine
Benedictine is a Louisville sandwich spread made from cucumber and cream cheese. It is a local tea-room classic, often served on sandwiches or crackers.
- Vegetarian
Derby Pie
Derby Pie is a Louisville dessert tart with chocolate chips and walnuts in a buttery crust, long associated with Derby season and local celebrations.
Jack Fry's
Refined restaurant in NuLu focused on seasonal American cooking with a thoughtful dining room and strong bourbon-friendly menu.
Plehn's Bakery
Longstanding local bakery and cafe best known for Derby Pie and other Louisville sweets in a casual, old-school setting.
Monnik Beer Co.
Classic German-American beer hall atmosphere with house beers, sausages, schnitzel, and a long-running place in Louisville dining culture.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are mid-priced, while transit is limited so many visitors budget extra for rideshares or car hire.
Average meal costs
- Budget
- $10-15 for fast food or a casual lunch.
- Mid-range
- $20-35 per person for a sit-down meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.
Plan your visit to Louisville, KY
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Louisville, KY.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Louisville, KY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and around popular attractions. Scams involving overcharging by taxi or ride-share drivers can occur, so using reputable services and confirming fares upfront is advised. Travelers should also be aware of distracted driver risks and practice standard safety precautions at night. Staying vigilant and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Florence, SC to Louisville, KY
Find answers to the most common questions about traveling from Florence, SC to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.
Yes, you can take a bus between Florence, SC and Louisville, KY.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Florence, SC to Louisville, KY
Most Florence, SC to Louisville, KY buses use the Florence, W Lucas St (TA Gas Station) to Louisville, W Broadway (Greyhound Bus Station) station pair. Use this guide to compare Florence, SC and Louisville, KY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Florence
Arrival bus stations in Louisville
Which Florence, SC station do buses to Louisville, KY leave from?
Buses from Florence, SC to Louisville, KY leave from Florence, W Lucas St (TA Gas Station). The station is 3 miles (6 km) from Florence, SC city centre at Florence, SC, USA.
Florence, W Lucas St (TA Gas Station)Florence, SC, USA
City-centre transport
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
TRUE
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Which Louisville, KY station do buses from Florence, SC arrive at?
Buses from Florence, SC to Louisville, KY arrive at Louisville, W Broadway (Greyhound Bus Station). Louisville, W Broadway (Greyhound Bus Station) is 0 miles (1 km) from Louisville, KY city centre.
Louisville, W Broadway (Greyhound Bus Station)1211 W Broadway, Louisville, KY 40203, USA
City-centre transport
Getting to Louisville, W Broadway (Greyhound Bus Station) from Louisville city centre
Louisville, W Broadway (Greyhound Bus Station) is 1 km from Louisville city centre. Public transport options include:
Bus23, 99 · 8m · €3 · every ~7 min
Louisville, W Broadway (Greyhound Bus Station) bus station facilities and services
Louisville, W Broadway (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Vending machines and nearby fast food restaurants.
Wi-Fi and ATMs
Free WiFi available in the waiting area. ATMs are aTMs available inside the station.
Tickets and information
Ticket office support is available at Louisville, W Broadway (Greyhound Bus Station).
Parking, taxis and toilets
Available at Louisville, W Broadway (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Louisville, W Broadway (Greyhound Bus Station): Wheelchair accessible entrances and facilities.
Bus stations for Florence, SC to Louisville, KY
Check bus stations information for Florence, SC and Louisville, KY, including where buses depart and arrive on this route.
Passengers board the bus most frequently from Florence, W Lucas St (TA Gas Station), which is located around 3 miles (6 km) away from the city centre, and they get off the bus at Louisville, W Broadway (Greyhound Bus Station), located 1 away from the city centre.
Most popular buses to and from Louisville, KY and Florence, SC
Most popular bus connections to Louisville, KY
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