Florence, SC to Louisville, KY bus with FlixBus

Sat, Nov 22
+ Add return
FlixBus
Southeastern Stages
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Southeastern Stages
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Florence, SC to Louisville, KY

Showing times and prices for Nov 23

Cheapest price

$341

Average price

$341

Fastest journey

18 h 55 m

Average duration

18 h 55 m

Buses per day

1

Distance

702 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Louisville, KY will cost around $341 if you buy it on the day, but the cheapest tickets can be found for only $341.

Fast buses

It's difficult to get from Florence, SC to Louisville, KY without transferring at least 2 times.

Southeastern Stages
08:05AM18h55
Florence, SC
03:00AMLouisville, KY
$3411One-way
2 transfers

Live departures

Florence, SC to Louisville, KY bus times

The table below shows live departures for Florence, SC to Louisville, KY buses for today, Saturday, November 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at 7:56 AM
ProviderDepartsDurationArrivesTransfers
Tickets
Southeastern Stages8:05 AM Florence, SC
18h55
3:00 AM Louisville, KY2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence, SC to Louisville, KY by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Nov 23
Mon
Nov 24
Tue
Nov 25
Wed
Nov 26
Thu
Nov 27
Fri
Nov 28
Sat
Nov 29

Journey information

Overview: Bus from Florence, SC to Louisville, KY

USAUSA
USAUSA
Icon of bus

Buses from Florence, SC to Louisville, KY run on average 3 times per day, taking around 15h 25m. Cheap bus tickets for this journey start at $157 (€128) if you book in advance.

The earliest bus runs at 01:35, the last at 23:00. The fastest bus covers the 436 miles (702 km) distance in 19h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
436 miles (702 km)
Average bus duration
15h 25m
Cheapest ticket price
$157 (€128)
Buses per day
3
Fastest bus
19h 45m
First bus
01:35
Last bus
23:00
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Southeastern Stages from Florence, SC to Louisville, KYYou can travel by bus between Florence, SC to Louisville, KY with FlixBus, Southeastern Stages for as low as $157 (€128). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Learn more about FlixBus
Luggage & cancellation policy
Average Duration
23h 10m
Cheapest Price
$156 (€128)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Southeastern Stages

Luggage & cancellation policy
Average Duration
18h 55m
Cheapest Price
$341 (€278)
Southeastern Stages frequency
1 a day

FAQs: Bus from Florence, SC to Louisville, KY

Find answers to the most common questions about traveling from Florence, SC to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Louisville, KY can start from as little as $157 (€128) when you book in advance. The average bus ticket price for Florence, SC to Louisville, KY is $189 (€154); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Louisville, KY is 22 h 45 min   to travel the 435 mile (701 km) long route, with around there are 3 buses per day. Journey times can vary on weekends and holidays.
The first bus from Florence, SC to Louisville, KY leaves at 12: 10AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Florence, SC to Louisville, KY leaves at 11: 40PM.
There are 3 buses a day from Florence, SC to Louisville, KY which require at least one change with FlixBus or Southeastern Stages. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Louisville, KY, you can count on FlixBus or Southeastern Stages for the best way to get you to Louisville, KY. You can also check all possible bus providers who offer a service to Louisville, KY from Florence, SC and compare the amenities they offer before buying a bus ticket.
The cheapest month to travel from Florence, SC to Louisville, KY by bus is December.
Yes, you can take a bus between Florence, SC and Louisville, KY.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Louisville, KY:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Louisville, KY for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Florence, SC to Louisville, KY depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Florence, SC to Louisville, KY, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Florence, SC to Louisville, KY.
    Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Louisville, KY:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Louisville, KY:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Florence, SC to Louisville, KY. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Florence, SC to Louisville, KY with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Florence, SC to Louisville, KY with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Florence, SC to Louisville, KY with the following bus company: FlixBus.

    popular bus stations

    Popular bus stations from Florence, SC to Louisville, KY

    Florence
    Louisville
    The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Louisville.
    Florence, S Irby St (Greyhound Bus Stop)
    information

    More options for your journey from Florence, SC to Louisville, KY

    Here are some other resources that might have the information you need

    Return journeys for buses from Louisville, KY to Florence, SC
    Trains from Florence, SC to Louisville, KY
    Tickets and more information for coaches to Florence, SC
    Tickets and more information for coaches to Louisville, KY

    Most popular buses to and from Louisville, KY and Florence, SC

    Bus Florence, SC - New York, NY
    Bus Florence, SC - Chicago, IL
    Bus Florence, SC - Los Angeles, CA
    Bus Florence, SC - Washington, DC
    Bus Florence, SC - Philadelphia, PA
    Bus Florence, SC - Orlando, FL
    Bus Florence, SC - Atlanta, GA
    Bus Florence, SC - Miami, FL
    Bus Florence, SC - Las Vegas, NV
    Bus Florence, SC - Tampa, FL
    Bus Florence, SC - Baltimore, MD
    Bus Florence, SC - New Orleans, LA
    Bus Florence, SC - Charlotte, NC
    Bus Florence, SC - Nashville, TN
    Bus Florence, SC - Raleigh, NC
    Bus Florence, SC - Cleveland, OH
    Bus Florence, SC - Richmond, VA
    Bus Florence, SC - Fayetteville, NC
    Bus Florence, SC - Bronx, NY
    Bus Florence, SC - Springfield, MA
    Bus Florence, SC - Greenville, SC
    Bus Florence, SC - Bridgeport, CT
    Bus Boston, MA - Louisville, KY
    Bus New York, NY - Louisville, KY
    Bus Chicago, IL - Louisville, KY
    Bus Los Angeles, CA - Louisville, KY
    Bus Washington, DC - Louisville, KY
    Bus Philadelphia, PA - Louisville, KY
    Bus Orlando, FL - Louisville, KY
    Bus Dallas, TX - Louisville, KY
    Bus Atlanta, GA - Louisville, KY
    Bus Miami, FL - Louisville, KY
    Bus Phoenix, AZ - Louisville, KY
    Bus Portland, OR - Louisville, KY
    Bus San Antonio, TX - Louisville, KY
    Bus Newark, NJ - Louisville, KY
    Bus Denver, CO - Louisville, KY
    Bus St. Louis, MO - Louisville, KY
    Bus Milwaukee, WI - Louisville, KY
    Bus Charlotte, NC - Louisville, KY
    Bus Nashville, TN - Louisville, KY
    Bus Pittsburgh, PA - Louisville, KY
    Bus Indianapolis, IN - Louisville, KY
    Bus Jacksonville, FL - Louisville, KY
    HomeBusesBuses in USABus tickets to Louisville, KYFlorence, SC to Louisville, KY bus

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone