4.9
4.6The cheapest and fastest buses from Florence, SC to Louisville, KY
Cheapest price on Sep 17
$75
Average ticket price on Sep 17
$75
Fastest journey on Sep 17
19 h 55 m
Average journey duration on Sep 17
19 h 55 m
Buses on Sep 17
1
Distance
702 km
The best way to find a cheap bus ticket from Florence, SC to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Louisville, KY will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $75.
It's difficult to get from Florence, SC to Louisville, KY without transferring at least 2 times.
FlixBus · FlixBus+
5:45 AM19h55Florence, W Lucas St (TA Gas Station), SC1:40 AMLouisville, W Broadway (Greyhound Bus Station), KY$751One-way2 transfers
- FlixBus · FlixBus+5:45 AM19h55Florence, W Lucas St (TA Gas Station), SC1:40 AMLouisville, W Broadway (Greyhound Bus Station), KY$751One-way2 transfers
Travel Information
Compare bus for Florence, SC to Louisville, KY
Omio recommends booking the bus as it is the most popular option from Florence, SC to Louisville, KY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $117 For those with little time, consider booking a bus, which has an average total journey time of 17h 0m. Average ticket prices depend on the travel mode: a bus costs an average of $117, while a bus costs an average of $117.
Distance: 436 miles (702 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$117 Average price Cheapest | $113 Average price (fuel + tolls) |
17h 0m Average total duration Fastest 16h 30m Onboard + 30m Additional time* | 9h 0m Average total duration (door-to-door) |
Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around $98 compared to roughly $113 in fuel and tolls — a saving of about $15. The journey takes 17h 53m versus 9h 0m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Florence, SC to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:45AM | Arrival Time 01:40AM | Duration 19h55 | Departure days Thu | Cheapest price $75 |
Operator Greyhound USA | Departure Time 04:10PM | Arrival Time 08:00AM | Duration 15h50 | Departure days Tue, Wed | Cheapest price $178 |
Operator FlixBus | Departure Time 04:55PM | Arrival Time 09:40AM | Duration 16h45 | Departure days Sun | Cheapest price $137 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 01:35PM | Duration 17h25 | Departure days Mon, Fri | Cheapest price $182 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 11:20PM | Duration 26h50 | Departure days Fri | Cheapest price $168 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 12:20AM | Duration 26h50 | Departure days Fri | Cheapest price $227 |
Live departures
Florence, SC to Louisville, KY bus times
The table below shows live departures for Florence, SC to Louisville, KY buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:10 PM Florence, SC | 15h50 | 8:00 AM Louisville, KY | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Louisville, KY by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Why should you book Florence, SC to Louisville, KY buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Florence, SC to Louisville, KY.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Florence, SC to Louisville, KY.
Journey information
Overview: Bus from Florence, SC to Louisville, KY
USAUSA
Buses from Florence, SC to Louisville, KY run on average 3 times per day, taking around 17h 53m. Cheap bus tickets for this journey start at $88 if you book in advance.
The earliest bus runs at 01:35, the last at 22:55. The fastest bus covers the 436 miles (702 km) distance in 15h 30m.
Distance 436 miles (702 km) |
Average bus duration 17h 53m |
Cheapest ticket price $88 |
Buses per day 3 |
Fastest bus 15h 30m |
First bus 1:35 AM |
Last bus 10:55 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Apr - Jun |
Bus providers: Greyhound, FlixBus from Florence, SC to Louisville, KYYou can travel by bus between Florence, SC to Louisville, KY with Greyhound, FlixBus for as low as $80. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Florence, SC to Louisville, KY
Find answers to the most common questions about traveling from Florence, SC to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Florence, SC to Louisville, KY
Most Florence, SC to Louisville, KY buses use the Florence, S Irby St (Greyhound Bus Stop) to Louisville, W Broadway (Greyhound Bus Station) station pair. Use this guide to compare Florence, SC and Louisville, KY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Florence, SC station do buses to Louisville, KY leave from?
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Which Louisville, KY station do buses from Florence, SC arrive at?
Getting to Louisville, W Broadway (Greyhound Bus Station) from Louisville city centre
Louisville, W Broadway (Greyhound Bus Station) is 1 km from Louisville city centre. Public transport options include:
Louisville, W Broadway (Greyhound Bus Station) bus station facilities and services
Louisville, W Broadway (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Vending machines and nearby fast food restaurants.
Wi-Fi and ATMs
Free WiFi available in the waiting area. ATMs are aTMs available inside the station.
Tickets and information
Ticket office support is available at Louisville, W Broadway (Greyhound Bus Station).
Parking, taxis and toilets
Available at Louisville, W Broadway (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Louisville, W Broadway (Greyhound Bus Station): Wheelchair accessible entrances and facilities.
Most popular bus connections from Florence, SC
More options for your journey from Florence, SC to Louisville, KY
Here are some other resources that might have the information you need
Most popular buses to and from Louisville, KY and Florence, SC
Most popular bus connections to Louisville, KY
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