Florence, SC to Durham, NC bus with FlixBus

Fri, Dec 19
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FlixBus
Southeastern Stages
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Southeastern Stages
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Travel Information

Compare train and bus for Florence, SC to Durham, NC

Omio recommends booking the bus as it is the most popular option from Florence, SC to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from €33. For those with little time consider booking a bus which can get you there in 5h 50m. The ticket price range depends on the travel mode: a bus costs an average of €33, and a train costs an average of €60.

Distance: 133 miles (215 km)

Compare bus with

Most popular
Bus
Train

€33

Average price

Cheapest

€60

Average price

6h 20m

Average total duration

Fastest

5h 50m

Onboard

+

30m

Additional time*

7h 37m

Average total duration

7h 7m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Florence, SC to Durham, NC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Florence, SC to Durham, NC

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Buses from Florence, SC to Durham, NC run on average 1 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at $41 (€33) if you book in advance.

The earliest bus runs at 00:05, the last at 21:15. The fastest bus covers the 133 miles (215 km) distance in 5h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
133 miles (215 km)
Average bus duration
5h 50m
Cheapest ticket price
$41 (€33)
Buses per day
1
Fastest bus
5h 45m
First bus
00:05
Last bus
21:15
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Southeastern Stages from Florence, SC to Durham, NCYou can travel by bus between Florence, SC to Durham, NC with FlixBus, Southeastern Stages for as low as $41 (€33). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
5h 45m
Cheapest Price
$41 (€33)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Southeastern Stages

Luggage & cancellation policy
Average Duration
10h 20m
Cheapest Price
$114 (€91)
Southeastern Stages frequency
1 a day

FAQs: Bus from Florence, SC to Durham, NC

Find answers to the most common questions about traveling from Florence, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Durham, NC can start from as little as $128 (€103) when you book in advance. The average bus ticket price for Florence, SC to Durham, NC is $128 (€103); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time from Florence, SC to Durham, NC is on average 10 h 20 min   for the 133 mile (214 km) long journey, but the time it takes to go to Durham, NC from Florence, SC by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Florence, SC to Durham, NC leaves at 1: 00AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Florence, SC to Durham, NC leaves at 9: 30PM.
There are 2 buses a day from Florence, SC to Durham, NC which require at least one change with FlixBus or Southeastern Stages. Schedules can vary on holidays or weekends with fewer buses.
For the best Florence, SC to Durham, NC bus to book, you can travel safely and comfortably with FlixBus or Southeastern Stages. However, it's always good to check all possible bus providers with services between Florence, SC and Durham, NC to compare what amenities they may offer.
It's helpful to compare your options as there are 2 ways to travel from Florence, SC to Durham, NC including taking a train or bus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Durham, NC:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Durham, NC for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Florence, SC to Durham, NC depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Florence, SC to Durham, NC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Florence, SC to Durham, NC.
    Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Durham, NC:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Durham, NC:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Florence, SC to Durham, NC. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Florence, SC to Durham, NC with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Florence, SC to Durham, NC with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Florence, SC to Durham, NC with the following bus company: FlixBus.

    popular bus stations

    Popular bus stations from Florence, SC to Durham, NC

    Florence
    Durham
    The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Durham.
    Florence, S Irby St (Greyhound Bus Stop)
    information

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