Florence, SC to Durham, NC bus with FlixBus

Sun, Jun 21
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Alsa
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Florence, SC to Durham, NC

Showing times and prices for Jun 21

Cheapest price

$46

Average price

$46

Fastest journey

5 h 30 m

Average duration

5 h 30 m

Buses per day

1

Distance

215 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Durham, NC will cost around $46 if you buy it on the day, but the cheapest tickets can be found for only $46.

Fast buses

It's difficult to get from Florence, SC to Durham, NC without transferring at least once.

  • Greyhound USA
    4:30 PM5h30
    Florence, SC
    10:00 PMDurham, NC
    $461One-way
    1 transfer

Travel Information

Compare train and bus for Florence, SC to Durham, NC

Omio recommends booking the bus as it is the most popular option from Florence, SC to Durham, NC among Omio's users. If you are prioritising price take the train with prices starting from $74. For those with little time consider booking a bus which can get you there in 5h 50m. The ticket price range depends on the travel mode: a train costs an average of $74, and a bus costs an average of $109.

Distance: 133 miles (215 km)

Compare bus with

Most popular
Bus
Train
Driving

$109

Average price

$103

Average price

Cheapest

$31

Average price

(fuel + tolls)

6h 20m

Average total duration

Fastest

5h 50m

Onboard

+

30m

Additional time*

9h 5m

Average total duration

8h 35m

Onboard

+

30m

Additional time*

2h 34m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence, SC to Durham, NC is a train with an average price of $103 (€84).

This is compared to other travel options from Florence, SC to Durham, NC:

A train is $6 (€5) less than a bus for this route with tickets for a bus from Florence, SC to Durham, NC costing on average $109 (€89).

The fastest way to travel from Florence, SC to Durham, NC is by bus with an average journey time of 5h 50m.

Other travel options to Durham, NC take longer:

Train takes on average 8h 35m.

It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Durham, NC including taking a train and bus.
We recommend using the bus as it is the most popular way to get from Florence, SC to Durham, NC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Florence, SC to Durham, NC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound USA
Departure Time
04:30PM
Arrival Time
10:00PM
Duration
5h30
Departure days
Mon, Tue, Wed, Fri, Sun
Cheapest price
$46
Operator
Greyhound
Departure Time
08:30PM
Arrival Time
02:00AM
Duration
5h30
Departure days
Thu
Cheapest price
$109

Compare prices and tickets Florence, SC to Durham, NC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27

Why should you book Florence, SC to Durham, NC buses with Omio?

FlixBus as well as Greyhound offer buses services from Florence, SC to Durham, NC.
Omio is an official ticket reseller for all your travel options from Florence, SC to Durham, NC.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Florence, SC to Durham, NC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Durham, NC.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Florence, SC to Durham, NC.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Durham, NC.

Journey information

Overview: Bus from Florence, SC to Durham, NC

USAUSA
USAUSA
Icon of bus

Buses from Florence, SC to Durham, NC run on average 2 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at $109 (€89) but you can travel from only $74 (€60) by train.

The earliest bus runs at 00:05, the last at 21:15. The fastest bus covers the 133 miles (215 km) distance in 5h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $74 (€60)
Distance
133 miles (215 km)
Average bus duration
5h 50m
Cheapest ticket price
$109 (€89)
Buses per day
2
Fastest bus
5h 30m
First bus
12:05 AM
Last bus
9:15 PM
Cheapest Month
Sep
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $74 (€60)

Bus providers: FlixBus, Greyhound from Florence, SC to Durham, NCYou can travel by bus between Florence, SC to Durham, NC with FlixBus, Greyhound for as low as $74 (€60). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
5h 45m
Cheapest Price
$40 (€33)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
5h 30m
Cheapest Price
$109 (€89)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Florence, SC to Durham, NC

Find answers to the most common questions about traveling from Florence, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Durham, NC can start from as little as $109 (€89) when you book in advance. The average bus ticket price for Florence, SC to Durham, NC is $109 (€89) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Durham, NC is 5h 30m to travel the 133 miles (215 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Durham, NC leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Durham, NC leaves at 9:15 PM.
There are 2 buses a day from Florence, SC to Durham, NC which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Durham, NC, you can count on FlixBus, Greyhound for the best way to get you to Durham, NC. You can also check all possible bus companies who offer a service between Florence, SC and Durham, NC and compare the amenities they offer before buying a bus ticket.
A trip to Durham, NC from Florence, SC is worth doing but not as a day trip with a journey time of 5h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Durham, NC is September.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Durham, NC including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Durham, NC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Durham, NC for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Florence, SC to Durham, NC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Durham, NC.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Durham, NC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Durham, NC:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Durham, NC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Durham, NC with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Florence, SC to Durham, NC with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Florence, SC to Durham, NC with the following bus company: FlixBus, Greyhound.
Since neither Florence, SC nor Durham, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Florence, SC to Durham, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Durham, NC, travelers should stay alert to common urban safety concerns such as petty theft, especially in crowded areas and public transit. Scams may include overcharging by unofficial taxi services or ride-share drivers, so using reputable transportation apps is advised. It's also important to avoid isolated areas after dark and keep personal belongings secure to reduce risk.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Florence, SC to Durham, NC

Most Florence, SC to Durham, NC buses use the Florence, S Irby St (Greyhound Bus Stop) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Florence, SC and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Florence
Arrival bus stations in Durham
Florence, S Irby St (Greyhound Bus Stop)

More options for your journey from Florence, SC to Durham, NC

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