Florence, SC to Durham, NC bus with FlixBus

Wed, Feb 04
+ Add return
FlixBus
Southeastern Stages
Costa Verde
Alsa
BlaBlaCar Bus
1,000+ travel companies
FlixBus
Southeastern Stages
Costa Verde
Alsa
BlaBlaCar Bus
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Florence, SC to Durham, NC

Showing times and prices for Feb 04

Cheapest price

$114

Average price

$114

Fastest journey

10 h 20 m

Average duration

10 h 20 m

Buses per day

1

Distance

215 km

Cheap tickets

The best way to find a cheap bus ticket from Florence, SC to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence, SC to Durham, NC will cost around $114 if you buy it on the day, but the cheapest tickets can be found for only $114.

Fast buses

It's difficult to get from Florence, SC to Durham, NC without transferring at least once.

Southeastern Stages
02:25PM10h20
Florence, SC
12:45AMDurham, NC
$1141One-way
1 transfer

Travel Information

Compare train and bus for Florence, SC to Durham, NC

Omio recommends booking the bus as it is the most popular option from Florence, SC to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from €33. For those with little time consider booking a bus which can get you there in 5h 50m. The ticket price range depends on the travel mode: a bus costs an average of €33, and a train costs an average of €60.

Distance: 133 miles (215 km)

Compare bus with

Most popular
Bus
Train

€33

Average price

Cheapest

€60

Average price

6h 20m

Average total duration

Fastest

5h 50m

Onboard

+

30m

Additional time*

7h 37m

Average total duration

7h 7m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

Florence, SC to Durham, NC bus times

The table below shows live departures for Florence, SC to Durham, NC buses for tomorrow, Wednesday, February 4. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:22 PM
ProviderDepartsDurationArrivesTransfers
Tickets
Southeastern Stages2:25 PM Florence, SC
10h20
12:45 AM Durham, NC1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence, SC to Durham, NC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Feb 04
Thu
Feb 05
Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
Mon
Feb 09
Tue
Feb 10

Why should you book Florence, SC to Durham, NC buses with Omio?

FlixBus as well as Southeastern Stages offer buses services from Florence, SC to Durham, NC.
Omio is an official ticket reseller for all your travel options from Florence, SC to Durham, NC.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Southeastern Stages to find the best option for your trip from Florence, SC to Durham, NC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Durham, NC.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Durham, NC.

Journey information

Overview: Bus from Florence, SC to Durham, NC

USAUSA
USAUSA
Icon of bus

Buses from Florence, SC to Durham, NC run on average 1 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at $41 (€33) if you book in advance.

The earliest bus runs at 00:05, the last at 21:15. The fastest bus covers the 133 miles (215 km) distance in 5h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
133 miles (215 km)
Average bus duration
5h 50m
Cheapest ticket price
$41 (€33)
Buses per day
1
Fastest bus
5h 45m
First bus
00:05
Last bus
21:15
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Southeastern Stages from Florence, SC to Durham, NCYou can travel by bus between Florence, SC to Durham, NC with FlixBus, Southeastern Stages for as low as $41 (€33). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
5h 45m
Cheapest Price
$41 (€33)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Southeastern Stages

Luggage & cancellation policy
Average Duration
10h 20m
Cheapest Price
$114 (€91)
Southeastern Stages frequency
1 a day

FAQs: Bus from Florence, SC to Durham, NC

Find answers to the most common questions about traveling from Florence, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Florence, SC to Durham, NC can start from as little as $41 (€33) when you book in advance. The average bus ticket price for Florence, SC to Durham, NC is $42 (€33) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Florence, SC to Durham, NC is 5h 45m to travel the 133 miles (215 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Florence, SC to Durham, NC leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Durham, NC leaves at 9:15 PM.
There are 1 buses a day from Florence, SC to Durham, NC which require at least one change with FlixBus, Southeastern Stages. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Florence, SC to Durham, NC, you can count on FlixBus, Southeastern Stages for the best way to get you to Durham, NC. You can also check all possible bus companies who offer a service between Florence, SC and Durham, NC and compare the amenities they offer before buying a bus ticket.
A trip to Durham, NC from Florence, SC is worth doing but not as a day trip with a journey time of 5h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Florence, SC to Durham, NC is September.
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Durham, NC including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Durham, NC:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Durham, NC for bus company FlixBus.
Whether you can cancel your bus ticket from Florence, SC to Durham, NC depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Florence, SC to Durham, NC.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Durham, NC:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Durham, NC:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Durham, NC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Durham, NC with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Durham, NC with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Durham, NC with the following bus company: FlixBus.

popular bus stations

Popular bus stations from Florence, SC to Durham, NC

Florence
Durham
The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Durham.
Florence, S Irby St (Greyhound Bus Stop)
information

Most popular bus connections from Florence, SC

Bus Florence, SC - Raleigh, NC

More options for your journey from Florence, SC to Durham, NC

Here are some other resources that might have the information you need

Tickets and more information for coaches to Florence, SC
Tickets and more information for coaches to Durham, NC

Most popular buses to and from Durham, NC and Florence, SC

Bus Florence, SC - New York, NY
Bus Florence, SC - Chicago, IL
Bus Florence, SC - Los Angeles, CA
Bus Florence, SC - Washington, DC
Bus Florence, SC - Philadelphia, PA
Bus Florence, SC - Orlando, FL
Bus Florence, SC - Atlanta, GA
Bus Florence, SC - Miami, FL
Bus Florence, SC - Las Vegas, NV
Bus Florence, SC - Tampa, FL
Bus Florence, SC - Baltimore, MD
Bus Florence, SC - Louisville, KY
Bus Florence, SC - Fayetteville, NC
Bus Florence, SC - Bronx, NY
Bus Florence, SC - Springfield, MA
Bus Florence, SC - Greenville, SC
Bus Florence, SC - Bridgeport, CT
Bus Florence, SC - Charleston, WV
Bus Florence, SC - Charleston, SC
Bus Florence, SC - Norwalk, CT
Bus Florence, SC - North Charleston, SC
Bus Florence, SC - St. Augustine, FL
Bus Boston, MA - Durham, NC
Bus New York, NY - Durham, NC
Bus Washington, DC - Durham, NC
Bus Philadelphia, PA - Durham, NC
Bus Orlando, FL - Durham, NC
Bus Dallas, TX - Durham, NC
Bus Atlanta, GA - Durham, NC
Bus Seattle, WA - Durham, NC
Bus Tampa, FL - Durham, NC
Bus Baltimore, MD - Durham, NC
Bus Newark, NJ - Durham, NC
Bus St. Louis, MO - Durham, NC
Bus Charlotte, NC - Durham, NC
Bus Nashville, TN - Durham, NC
Bus Austin, TX - Durham, NC
Bus Raleigh, NC - Durham, NC
Bus Cleveland, OH - Durham, NC
Bus Richmond, VA - Durham, NC
Bus Columbus, OH - Durham, NC
Bus Toronto, ON - Durham, NC
Bus Norfolk, VA - Durham, NC
Bus Birmingham, AL - Durham, NC
HomeBusesBuses in USABus tickets to Durham, NCFlorence, SC to Durham, NC bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone