Des Moines, IA to Milwaukee, WI bus with Greyhound

Fri, Nov 07
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Greyhound
Burlington Trailways
FlixBus
Alsa
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1,000+ travel companies
Greyhound
Burlington Trailways
FlixBus
Alsa
BlaBlaCar Bus
1,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to Milwaukee, WI

Showing times and prices for Nov 07

Cheapest price

$73

Average price

$73

Fastest journey

11 h 15 m

Average duration

12 h 22 m

Buses per day

3

Distance

495 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Milwaukee, WI is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Milwaukee, WI will cost around $73 if you buy it on the day, but the cheapest tickets can be found for only $73.

Fast buses

It's difficult to get from Des Moines, IA to Milwaukee, WI without transferring at least once.

Greyhoundundefined · undefined
09:30AM14h15
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
11:45PMMilwaukee, Intermodal Station
$731One-way
1 transfer
Greyhound+FlixBusFlixBus
05:30AM11h35
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
05:05PMMilwaukee, Intermodal Station
$731One-way
1 transfer
Greyhound+FlixBusFlixBus
05:30AM11h15
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
04:45PMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI
$741One-way
1 transfer

Travel Information

Compare bus and flight for Des Moines, IA to Milwaukee, WI

Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Milwaukee, WI among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 5h 21m. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €120.

Distance: 307 miles (495 km)

Compare bus with

Most popular
Bus
Flight

€66

Average price

Cheapest

€223

Average price

10h 10m

Average total duration

9h 40m

Onboard

+

30m

Additional time*

8h 21m

Average total duration

Fastest

5h 21m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Des Moines, IA to Milwaukee, WI Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
05:30AM
Arrival Time
05:05PM
Duration
11h35
Departure days
Fri
Cheapest price
$73
Operator
Greyhound
Departure Time
09:30AM
Arrival Time
11:45PM
Duration
14h15
Departure days
Fri
Cheapest price
$73

Live departures

Des Moines, IA to Milwaukee, WI bus times

The table below shows live departures for Des Moines, IA to Milwaukee, WI buses for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated bus journeys.

Last updated at 3:23 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound+meinfernbus_flixbusFlixBus11:30 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
11h15
10:45 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI1 transfer
greyhound+meinfernbus_flixbusFlixBus11:30 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
11h35
11:05 PM Milwaukee, Intermodal Station1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Milwaukee, WI by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 07
Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
Nov 12
Thu
Nov 13

Journey information

Overview: Bus from Des Moines, IA to Milwaukee, WI

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to Milwaukee, WI run on average 2 times per day, taking around 9h 40m. Cheap bus tickets for this journey start at $49 (€40) if you book in advance.

The earliest bus runs at 03:20, the last at 09:30. The fastest bus covers the 307 miles (495 km) distance in 10h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
307 miles (495 km)
Average bus duration
9h 40m
Cheapest ticket price
$49 (€40)
Buses per day
2
Fastest bus
10h 45m
First bus
03:20
Last bus
09:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, Burlington Trailways from Des Moines, IA to Milwaukee, WIYou can travel by bus between Des Moines, IA to Milwaukee, WI with Greyhound, Burlington Trailways for as low as $49 (€40). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
$64 (€52)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Burlington Trailways

Luggage & cancellation policy
Average Duration
9h 40m
Cheapest Price
$182 (€148)
Burlington Trailways frequency
1 a day

FAQs: Bus from Des Moines, IA to Milwaukee, WI

Find answers to the most common questions about traveling from Des Moines, IA to Milwaukee, WI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milwaukee, WI, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Milwaukee, WI can start from as little as $71 (€57) when you book in advance. The average bus ticket price for Des Moines, IA to Milwaukee, WI is $119 (€97); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Des Moines, IA to Milwaukee, WI bus travel time is 12 h 35 min   for the 307 mile (495 km) long journey, but the duration can vary if you travel on weekends and holidays.
The first bus from Des Moines, IA to Milwaukee, WI leaves at 3: 20AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Des Moines, IA to Milwaukee, WI leaves at 11: 30PM.
There are 2 buses a day from Des Moines, IA to Milwaukee, WI which require at least one change with Greyhound or Burlington Trailways. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Milwaukee, WI, you can count on Greyhound or Burlington Trailways for the best way to get you to Milwaukee, WI. You can also check all possible bus companies who offer a service between Des Moines, IA and Milwaukee, WI and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from Des Moines, IA to Milwaukee, WI is November.
You have options as you can travel to Milwaukee, WI from Des Moines, IA 2 different ways: bus or flight.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Milwaukee, WI:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Milwaukee, WI for bus company Greyhound.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Des Moines, IA to Milwaukee, WI depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Des Moines, IA to Milwaukee, WI, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Des Moines, IA to Milwaukee, WI.
    Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Milwaukee, WI:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Milwaukee, WI:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from Des Moines, IA to Milwaukee, WI.
    You can reserve your seat on the bus from Des Moines, IA to Milwaukee, WI with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from Des Moines, IA to Milwaukee, WI with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from Des Moines, IA to Milwaukee, WI with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from Des Moines, IA to Milwaukee, WI

    Des Moines
    Milwaukee
    Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop)
    information
    Milwaukee, Intermodal Station
    information

    Most popular buses to and from Milwaukee, WI and Des Moines, IA

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