The cheapest and fastest buses from Des Moines, IA to Milwaukee, WI
Cheapest price
$187
Average price
$187
Fastest journey
9 h 40 m
Average duration
9 h 40 m
Buses per day
1
Distance
495 km
The best way to find a cheap bus ticket from Des Moines, IA to Milwaukee, WI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Milwaukee, WI will cost around $187 if you buy it on the day, but the cheapest tickets can be found for only $187.
It's difficult to get from Des Moines, IA to Milwaukee, WI without transferring at least once.


Travel Information
Compare bus and flight for Des Moines, IA to Milwaukee, WI
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Milwaukee, WI among Omio's users. If you are prioritising price take the bus with prices starting from €59. For those with little time consider booking a flight which can get you there in 5h 23m. The ticket price range depends on the travel mode: a bus costs an average of €59, and a flight costs an average of €138.
Distance: 307 miles (495 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€88 Average price Cheapest | €235 Average price |
10h 10m Average total duration 9h 40m Onboard + 30m Additional time* | 8h 23m Average total duration Fastest 5h 23m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Des Moines, IA to Milwaukee, WI bus times
The table below shows live departures for Des Moines, IA to Milwaukee, WI buses for tomorrow, Sunday, February 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:45 AM Des Moines, IA | 9h40 | 6:25 PM Milwaukee, WI | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Milwaukee, WI by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 15
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Feb 21
Why should you book Des Moines, IA to Milwaukee, WI buses with Omio?
Why book with Omio vs Burlington Trailways?
- Compare with other providers: On Omio, you can not only buy tickets for Burlington Trailways, but also compare tickets for the likes of Greyhound to find the best option for your trip from Des Moines, IA to Milwaukee, WI.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Burlington Trailways with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Milwaukee, WI.
Why book with Omio over Wanderu?
- Official reseller: Burlington Trailways tickets can only be bought on Omio or Burlington Trailways's website as Omio is the only official third party seller for Burlington Trailways tickets. Wanderu do not sell Burlington Trailways tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Milwaukee, WI.
Journey information
Overview: Bus from Des Moines, IA to Milwaukee, WI
Buses from Des Moines, IA to Milwaukee, WI run on average 2 times per day, taking around 9h 40m. Cheap bus tickets for this journey start at $75 (€59) if you book in advance.
The earliest bus runs at 03:20, the last at 09:45. The fastest bus covers the 307 miles (495 km) distance in 11h 15m.
Distance 307 miles (495 km) |
Average bus duration 9h 40m |
Cheapest ticket price $75 (€59) |
Buses per day 2 |
Fastest bus 11h 15m |
First bus 03:20 |
Last bus 09:45 |
Bus providers: Greyhound, Burlington Trailways from Des Moines, IA to Milwaukee, WIYou can travel by bus between Des Moines, IA to Milwaukee, WI with Greyhound, Burlington Trailways for as low as $75 (€59). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Burlington Trailways
FAQs: Bus from Des Moines, IA to Milwaukee, WI
Find answers to the most common questions about traveling from Des Moines, IA to Milwaukee, WI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milwaukee, WI, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Des Moines, IA to Milwaukee, WI
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Milwaukee, WI
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