The cheapest and fastest buses from Des Moines, IA to Los Angeles, CA
Cheapest price
$414
Average price
$414
Fastest journey
2 d 11 h 45 m
Average duration
2 d 11 h 45 m
Buses per day
1
Distance
2311 km
The best way to find a cheap bus ticket from Des Moines, IA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Los Angeles, CA will cost around $414 if you buy it on the day, but the cheapest tickets can be found for only $414.
Of the 1 buses that leave Des Moines, IA for Los Angeles, CA on Tue, Feb 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Feb 17 the direct buses cover the 2311 km distance in an average of 2 d 11 h 45 m but if you time it right, some buses will get you there in just 2 d 11 h 45 m .
On Tue, Feb 17 the slowest buses will take 2 d 11 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Des Moines, IA to Los Angeles, CA
Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from €140. For those with little time consider booking a flight which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of €140, and a flight costs an average of €143.
Distance: 1435 miles (2311 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€277 Average price Cheapest | €287 Average price |
43h 12m Average total duration 42h 42m Onboard + 30m Additional time* | 7h 54m Average total duration Fastest 4h 54m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Des Moines, IA to Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:30AM | Arrival Time 03:00PM | Duration 59h30 | Departure days Mon | Cheapest price $558 |
Operator Greyhound | Departure Time 07:15PM | Arrival Time 08:15AM | Duration 39h00 | Departure days Mon, Wed | Cheapest price $371 |
Live departures
Des Moines, IA to Los Angeles, CA bus times
The table below shows live departures for Des Moines, IA to Los Angeles, CA buses for tomorrow, Tuesday, February 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets | |
|---|---|---|---|---|---|---|
undefined · undefined · undefined | 1:15 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 39h00 | 4:15 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 2 transfers | ||
![]() | 10:30 AM Des Moines, IA | 59h45 | 10:15 PM Los Angeles, CA | 0 transfersDirect | ||
This is the last bus of the day. | ||||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Los Angeles, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 17
Feb 18
Feb 19
Feb 20
Feb 21
Feb 22
Feb 23
Why should you book Des Moines, IA to Los Angeles, CA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Des Moines, IA to Los Angeles, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Los Angeles, CA.
Why book with Omio over Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Des Moines, IA to Los Angeles, CA.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Los Angeles, CA.
Journey information
Overview: Bus from Des Moines, IA to Los Angeles, CA
Buses from Des Moines, IA to Los Angeles, CA run on average 2 times per day, taking around 42h 42m. Cheap bus tickets for this journey start at $177 (€140) if you book in advance.
The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 1435 miles (2311 km) distance in 39h 0m.
Distance 1435 miles (2311 km) |
Average bus duration 42h 42m |
Cheapest ticket price $177 (€140) |
Buses per day 2 |
Fastest bus 39h 0m |
First bus 00:25 |
Last bus 23:50 |
Bus providers: Greyhound, FlixBus from Des Moines, IA to Los Angeles, CAYou can travel by bus between Des Moines, IA to Los Angeles, CA with Greyhound, FlixBus for as low as $177 (€140). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Des Moines, IA to Los Angeles, CA
Find answers to the most common questions about traveling from Des Moines, IA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Des Moines, IA to Los Angeles, CA
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Los Angeles, CA
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