Des Moines, IA to Los Angeles, CA bus with Greyhound

Tue, May 19
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The cheapest and fastest buses from Des Moines, IA to Los Angeles, CA

Showing times and prices for May 20

Cheapest price

$343

Average price

$427

Fastest journey

1 d 14 h 40 m

Average duration

1 d 14 h 50 m

Buses per day

2

Distance

2311 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Los Angeles, CA will cost around $427 if you buy it on the day, but the cheapest tickets can be found for only $343.

Fast buses

Of the 2 buses that leave Des Moines, IA for Los Angeles, CA on Wed, May 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, May 20 the direct buses cover the 2311 km distance in an average of 1 d 14 h 50 m but if you time it right, some buses will get you there in just 1 d 14 h 40 m .

On Wed, May 20 the slowest buses will take 1 d 15 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    12:35 AM38h40
    Des Moines, IA
    3:15 PMLos Angeles, CA
    $3431One-way
    0 transfers
  • Greyhound
    1:15 AM39h00
    Des Moines, IA
    4:15 PMLos Angeles, CA
    $5111One-way
    0 transfers

Travel Information

Compare bus and flight for Des Moines, IA to Los Angeles, CA

Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $169. For those with little time consider booking a flight which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of $169, and a flight costs an average of $124.

Distance: 1435 miles (2311 km)

Compare bus with

Most popular
Bus
Flight
Driving

$357

Average price

Cheapest

$360

Average price

$345

Average price

(fuel + tolls)

44h 0m

Average total duration

43h 30m

Onboard

+

30m

Additional time*

7h 54m

Average total duration

Fastest

4h 54m

Onboard

+

3h 0m

Additional time*

24h 14m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Des Moines, IA to Los Angeles, CA is a bus with an average price of $357 (€288).

This is compared to other travel options from Des Moines, IA to Los Angeles, CA:

A bus is $4 (€3) less than a flight for this route with tickets for a flight from Des Moines, IA to Los Angeles, CA costing on average $360 (€291).

The fastest way to travel from Des Moines, IA to Los Angeles, CA is by flight with an average journey time of 4h 54m.

Other travel options to Los Angeles, CA take longer:

Bus takes on average 43h 30m.

It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Los Angeles, CA including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Los Angeles, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Des Moines, IA to Los Angeles, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:15AM
Arrival Time
03:15PM
Duration
39h00
Departure days
Mon, Thu, Sat, Sun
Cheapest price
$176
Operator
Greyhound
Departure Time
12:35AM
Arrival Time
03:15PM
Duration
38h40
Departure days
Mon, Tue, Wed, Thu, Sat, Sun
Cheapest price
$330
Operator
Greyhound
Departure Time
01:15AM
Arrival Time
01:05PM
Duration
59h50
Departure days
Mon, Tue, Wed, Thu, Sat
Cheapest price
$169
Operator
Greyhound
Departure Time
11:30AM
Arrival Time
11:00PM
Duration
59h30
Departure days
Mon
Cheapest price
$257
Operator
Greyhound
Departure Time
04:20PM
Arrival Time
03:30PM
Duration
49h10
Departure days
Thu
Cheapest price
$282
Operator
Greyhound
Departure Time
07:35PM
Arrival Time
08:15AM
Duration
38h40
Departure days
Thu
Cheapest price
$244
Operator
Greyhound
Departure Time
09:20PM
Arrival Time
10:30PM
Duration
49h10
Departure days
Fri
Cheapest price
$362

Live departures

Des Moines, IA to Los Angeles, CA bus times

The table below shows live departures for Des Moines, IA to Los Angeles, CA buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound11:30 AM Des Moines, IA
59h30
11:00 PM Los Angeles, CA0 transfersDirect
Tuesday, May 19
Greyhound12:35 AM Des Moines, IA
38h40
3:15 PM Los Angeles, CA0 transfersDirect
Greyhound1:15 AM Des Moines, IA
39h00
4:15 PM Los Angeles, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Los Angeles, CA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
May 19
Wed
May 20
Thu
May 21
Fri
May 22
Sat
May 23
Sun
May 24
Mon
May 25

Why should you book Des Moines, IA to Los Angeles, CA buses with Omio?

Greyhound operates all buses services from Des Moines, IA to Los Angeles, CA.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Los Angeles, CA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Los Angeles, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Los Angeles, CA.

Journey information

Overview: Bus from Des Moines, IA to Los Angeles, CA

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to Los Angeles, CA run on average 2 times per day, taking around 43h 30m. Cheap bus tickets for this journey start at $169 (€136) but you can travel from only $124 (€100) by flight.

The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 1435 miles (2311 km) distance in 38h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $124 (€100)
Distance
1435 miles (2311 km)
Average bus duration
43h 30m
Cheapest ticket price
$169 (€136)
Buses per day
2
Fastest bus
38h 40m
First bus
12:25 AM
Last bus
11:50 PM
Cheapest Month
Apr
Cheapest Day
Thu
High Season
Apr - Jun
Low Season
Oct - Dec
Busiest Day
Sat
Least Busy Day
Sat
Best time to book
91 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $124 (€100)

Bus providers: Greyhound from Des Moines, IA to Los Angeles, CAYou can travel by bus between Des Moines, IA to Los Angeles, CA with Greyhound for as low as $124 (€100). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
38h 40m
Cheapest Price
$169 (€136)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Los Angeles

Things to do in Los Angeles

Discover the best of Los Angeles — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles trip today.

  • Must visit

The Getty Center

A renowned art museum in Los Angeles known for its impressive architecture and expansive art collection, including European paintings and decorative arts.

  • Must visit

Los Angeles County Museum of Art (LACMA)

The largest art museum in the western United States, offering a comprehensive view of art history.

  • Recommended

The Broad

A contemporary art museum with a distinctive honeycomb-like exterior, known for its impressive collection of postwar and contemporary art.

US Dollar

Los Angeles is generally expensive, especially in popular tourist areas and for accommodation.

Average meal costs

Budget
$8-15 for fast food or a quick meal.
Mid-range
$20-40 per person for a meal.
Fine dining
$75+ per person at upscale restaurants.
Coffee
$3-5 for a cappuccino.

Tipping culture

15-20% in restaurants, round up or add a few dollars for taxis, not expected in cafes.

FAQs: Bus from Des Moines, IA to Los Angeles, CA

Find answers to the most common questions about traveling from Des Moines, IA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Los Angeles, CA can start from as little as $169 (€136) when you book in advance. The average bus ticket price for Des Moines, IA to Los Angeles, CA is $357 (€288) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Los Angeles, CA is 38h 40m to travel the 1435 miles (2311 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Los Angeles, CA leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Los Angeles, CA leaves at 11:50 PM.
There are 2 buses a day from Des Moines, IA to Los Angeles, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Los Angeles, CA, you can count on Greyhound for the best way to get you to Los Angeles, CA. You can also check all possible bus companies who offer a service between Des Moines, IA and Los Angeles, CA and compare the amenities they offer before buying a bus ticket.
A trip to Los Angeles, CA from Des Moines, IA is worth doing but not as a day trip with a journey time of 38h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Los Angeles, CA is April.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Los Angeles, CA including taking a bus and flight.
Yes, there are bathrooms on board the bus from Des Moines, IA to Los Angeles, CA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Los Angeles, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Los Angeles, CA are:
  • Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
  • The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
  • Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
  • Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
  • Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
The best things to do in Los Angeles, CA include:
  • Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
  • Visit the historic El Capitan Theatre for a classic movie experience
  • Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
  • Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
  • Discover the unique exhibits at the Natural History Museum of Los Angeles County.
Whether you can cancel your bus ticket from Des Moines, IA to Los Angeles, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Los Angeles, CA.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Los Angeles, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Los Angeles, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Los Angeles, CA.
You can reserve your seat on the bus from Des Moines, IA to Los Angeles, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Los Angeles, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Los Angeles, CA with the following bus company: Greyhound.
Since neither Des Moines, IA nor Los Angeles, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Los Angeles, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Los Angeles, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas like Hollywood and Venice Beach. Common scams include fake ticket vendors near popular attractions and overcharging by unlicensed ride services. It's important to use official transportation options, stay aware of surroundings, and avoid sharing personal information with strangers to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Des Moines, IA to Los Angeles, CA

Des Moines
Los Angeles
Los Angeles, Patsaouras Transit Plaza (Union Station)
information
Los Angeles, Cesar E Chavez / Vignes
information
Los Angeles, Gayley / Strathmore
information

Most popular buses to and from Los Angeles, CA and Des Moines, IA

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