- Must visit
The Getty Center
Major hilltop art museum with European paintings, decorative arts, gardens, and panoramic city views.
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The cheapest and fastest buses from Des Moines, IA to Los Angeles, CA
Showing times and prices for Jul 03
Cheapest price
$293
Average price
$347
Fastest journey
1 d 14 h 40 m
Average duration
1 d 19 h 55 m
Buses per day
2
Distance
2311 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Los Angeles, CA will cost around $347 if you buy it on the day, but the cheapest tickets can be found for only $293.
Fast buses
It's difficult to get from Des Moines, IA to Los Angeles, CA without transferring at least 2 times.
· · 7:35 PM38h40Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA8:15 AMLos Angeles, Patsaouras Transit Plaza (Union Station), CA$2931One-way2 transfers- · +
FlixBus4:20 PM49h10Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA3:30 PMLos Angeles, Cesar E Chavez / Vignes, CA$4011One-way2 transfers
- · · 7:35 PM38h40Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA8:15 AMLos Angeles, Patsaouras Transit Plaza (Union Station), CA$2931One-way2 transfers
- · +FlixBus4:20 PM49h10Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA3:30 PMLos Angeles, Cesar E Chavez / Vignes, CA$4011One-way2 transfers
Travel Information
Compare bus and flight for Des Moines, IA to Los Angeles, CA
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $166. For those with little time consider booking a flight which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of $166, and a flight costs an average of $122.
Distance: 1435 miles (2311 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$350 Average price Cheapest | $354 Average price | $338 Average price (fuel + tolls) |
44h 0m Average total duration 43h 30m Onboard + 30m Additional time* | 7h 54m Average total duration Fastest 4h 54m Onboard + 3h 0m Additional time* | 24h 14m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Des Moines, IA to Los Angeles, CA is a bus with an average price of $350 (€288).
This is compared to other travel options from Des Moines, IA to Los Angeles, CA:
A bus is $4 (€3) less than a flight for this route with tickets for a flight from Des Moines, IA to Los Angeles, CA costing on average $354 (€291).
The fastest way to travel from Des Moines, IA to Los Angeles, CA is by flight with an average journey time of 4h 54m.
Other travel options to Los Angeles, CA take longer:
Bus takes on average 43h 30m.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Los Angeles, CA including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Los Angeles, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Des Moines, IA to Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 03:15PM | Duration 39h00 | Departure days Mon, Thu, Sun | Cheapest price $172 |
Operator Greyhound | Departure Time 12:35AM | Arrival Time 03:15PM | Duration 38h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $324 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 04:15PM | Duration 39h00 | Departure days Mon, Tue, Wed, Thu | Cheapest price $334 |
Operator Greyhound | Departure Time 11:30AM | Arrival Time 11:00PM | Duration 59h30 | Departure days Mon, Thu | Cheapest price $252 |
Operator Greyhound | Departure Time 04:20PM | Arrival Time 03:30PM | Duration 49h10 | Departure days Fri | Cheapest price $401 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 08:15AM | Duration 38h40 | Departure days Fri | Cheapest price $293 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 10:30PM | Duration 49h10 | Departure days Thu | Cheapest price $329 |
Live departures
Des Moines, IA to Los Angeles, CA bus times
The table below shows live departures for Des Moines, IA to Los Angeles, CA buses for today, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 11:30 AM Des Moines, IA | 59h30 | 11:00 PM Los Angeles, CA | 0 transfersDirect | |
| 9:20 PM Des Moines, IA | 49h10 | 10:30 PM Los Angeles, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Los Angeles, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jul 03
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Why should you book Des Moines, IA to Los Angeles, CA buses with Omio?
Greyhound operates all buses services from Des Moines, IA to Los Angeles, CA.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Los Angeles, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Los Angeles, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Los Angeles, CA.
Journey information
Overview: Bus from Des Moines, IA to Los Angeles, CA
USAUSA
Buses from Des Moines, IA to Los Angeles, CA run on average 2 times per day, taking around 43h 30m. Cheap bus tickets for this journey start at $166 (€136) but you can travel from only $122 (€100) by flight.
The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 1435 miles (2311 km) distance in 38h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $122 (€100)
Distance 1435 miles (2311 km) |
Average bus duration 43h 30m |
Cheapest ticket price $166 (€136) |
Buses per day 2 |
Fastest bus 38h 40m |
First bus 12:25 AM |
Last bus 11:50 PM |
Cheapest Month Apr |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 91 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $122 (€100)
Bus providers: Greyhound from Des Moines, IA to Los Angeles, CAYou can travel by bus between Des Moines, IA to Los Angeles, CA with Greyhound for as low as $122 (€100). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
38h 40m
Cheapest Price
$166 (€136)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Los Angeles
Things to do in Los Angeles
Discover the best of Los Angeles — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles trip today.
- Must visit
Los Angeles County Museum of Art (LACMA)
The largest art museum in the western United States, known for broad global collections and the Urban Light installation.
- Must visit
The Broad
Contemporary art museum with a high-profile collection featuring works by Yayoi Kusama, Jeff Koons, and Jean-Michel Basquiat.
- Must visit
Griffith Park
Vast urban park with trails, scenic overlooks, and access to some of the city’s best outdoor viewpoints.
- Must visit
Santa Monica Pier
Classic Southern California waterfront area popular for ocean views, walks, and iconic beach atmosphere.
- Must visit
Venice Beach Boardwalk
Famous beachfront promenade known for street culture, murals, skate energy, and people-watching.
French Dip Sandwich
A Los Angeles classic of thinly sliced roast beef on a roll, usually served with savory jus for dipping. It is one of the city’s most iconic old-school sandwiches.
- Gluten-free
Street Tacos
Small corn-tortilla tacos filled with meats such as carne asada, al pastor, or carnitas, topped simply with onion, cilantro, and salsa. They reflect the city’s deep Mexican culinary influence.
- Gluten-free
Korean Barbecue
Grilled marinated meats cooked at the table, commonly enjoyed with banchan in Koreatown. Los Angeles is especially famous for its vibrant Korean barbecue culture.
Bestia
Popular upscale restaurant in the Arts District known for house-made charcuterie, pasta, and a stylish industrial setting.
Philippe The Original
Historic casual eatery best known for the French dip sandwich, old-school counter service, and classic Los Angeles atmosphere.
Guelaguetza
Well-known Oaxacan restaurant celebrated for mole, tlayudas, and lively traditional flavors in a vibrant setting.
United States Dollar
Los Angeles is costly for visitors, especially lodging, parking, and dining. Casual food is manageable, but transport and attractions add up quickly.
Average meal costs
- Budget
- USD 10-18 for fast food, tacos, or a simple cafe meal.
- Mid-range
- USD 25-45 per person at a casual sit-down restaurant.
- Fine dining
- USD 90+ per person before drinks, tax, and tip.
- Coffee
- USD 4-7 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20% is common for good service. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff and valet.
FAQs: Bus from Des Moines, IA to Los Angeles, CA
Find answers to the most common questions about traveling from Des Moines, IA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Des Moines, IA to Los Angeles, CA can start from as little as $166 (€136) when you book in advance. The average bus ticket price for Des Moines, IA to Los Angeles, CA is $350 (€288) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Los Angeles, CA is 38h 40m to travel the 1435 miles (2311 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Los Angeles, CA leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Los Angeles, CA leaves at 11:50 PM.
There are 2 buses a day from Des Moines, IA to Los Angeles, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Los Angeles, CA, you can count on Greyhound for the best way to get you to Los Angeles, CA. You can also check all possible bus companies who offer a service between Des Moines, IA and Los Angeles, CA and compare the amenities they offer before buying a bus ticket.
A trip to Los Angeles, CA from Des Moines, IA is worth doing but not as a day trip with a journey time of 38h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Los Angeles, CA is April.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Los Angeles, CA including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Los Angeles, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Los Angeles, CA for bus company Greyhound.
Some of the most interesting sights to explore in Los Angeles, CA are:
- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
The best things to do in Los Angeles, CA include:
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
Whether you can cancel your bus ticket from Des Moines, IA to Los Angeles, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Los Angeles, CA.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Los Angeles, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Los Angeles, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Los Angeles, CA.
You can reserve your seat on the bus from Des Moines, IA to Los Angeles, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Los Angeles, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Los Angeles, CA with the following bus company: Greyhound.
Since neither Des Moines, IA nor Los Angeles, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Los Angeles, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Los Angeles, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas like Hollywood and Venice Beach. Common scams include fake ticket vendors near popular attractions and overcharging by unlicensed ride services. It's important to use official transportation options, stay aware of surroundings, and avoid sharing personal information with strangers to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Des Moines, IA to Los Angeles, CA
Most Des Moines, IA to Los Angeles, CA buses use the to Los Angeles, Patsaouras Transit Plaza (Union Station) station pair, with some services arriving at Los Angeles, Cesar E Chavez / Vignes. Use this guide to compare Des Moines, IA and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Des Moines
Arrival bus stations in Los Angeles
Los Angeles, Patsaouras Transit Plaza (Union Station)
City-centre transport
Getting to Los Angeles, Patsaouras Transit Plaza (Union Station) from Los Angeles city centre
Bus4X · 8m · $2
SubwayMetro B Line, Metro D Line · 12m · $2 · every ~24 min
Los Angeles, Cesar E Chavez / Vignes
City-centre transport
Getting to Los Angeles, Cesar E Chavez / Vignes from Los Angeles city centre
Bus40, 74 · 3m · $2 · every ~15 min
33 · 4m · $2 · every ~9 min
D · 11m · $5 · every ~12 min
490, 495, 499, 699, 493, 498, 707 · 13m · $7 · every ~9 min
TramMetro A Line · 10m · $2 · every ~12 min
SubwayMetro B Line, Metro D Line · 10m · $2 · every ~24 min
Los Angeles, Gayley / Strathmore
City-centre transport
Getting to Los Angeles, Gayley / Strathmore from Los Angeles city centre
BusFlixBus N2002, FlixBus N2030, FlixBus 2000 · 25m · $2
431B, 431 · 41m · $5
20 · 1h 4m · $2 · every ~3 min
20 · 1h 32m · $2 · every ~8 min
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Los Angeles, CA
Here are some other resources that might have the information you need
Most popular buses to and from Los Angeles, CA and Des Moines, IA
Most popular bus connections to Los Angeles, CA
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