The cheapest and fastest buses from Des Moines, IA to Portland, OR
Cheapest price
$281
Average price
$281
Fastest journey
3 d 18 h 10 m
Average duration
3 d 18 h 10 m
Buses per day
1
Distance
2369 km
The best way to find a cheap bus ticket from Des Moines, IA to Portland, OR is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Portland, OR will cost around $281 if you buy it on the day, but the cheapest tickets can be found for only $281.
Of the 1 buses that leave Des Moines, IA for Portland, OR on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct buses cover the 2369 km distance in an average of 3 d 18 h 10 m but if you time it right, some buses will get you there in just 3 d 18 h 10 m .
On Tue, Dec 23 the slowest buses will take 3 d 18 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Des Moines, IA to Portland, OR
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Portland, OR among Omio's users. If you are prioritising price take the flight with prices starting from €114. For those with little time consider booking a flight which can get you there in 5h 39m. The ticket price range depends on the travel mode: a flight costs an average of €114, and a bus costs an average of €211.
Distance: 1472 miles (2369 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€277 Average price | €232 Average price Cheapest |
62h 34m Average total duration 62h 4m Onboard + 30m Additional time* | 8h 39m Average total duration Fastest 5h 39m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Live departures
Des Moines, IA to Portland, OR bus times
The table below shows live departures for Des Moines, IA to Portland, OR buses for today, Monday, December 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:30 AM Des Moines, IA | 90h10 | 4:40 AM Portland, OR | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Portland, OR by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 23
Dec 24
Dec 25
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Dec 29
Journey information
Overview: Bus from Des Moines, IA to Portland, OR
Buses from Des Moines, IA to Portland, OR run on average 1 times per day, taking around 62h 4m. Cheap bus tickets for this journey start at $263 (€211) but you can travel from only $142 (€114) by flight.
The earliest bus runs at 02:00, the last at 20:00. The fastest bus covers the 1472 miles (2369 km) distance in 90h 10m.
Distance 1472 miles (2369 km) |
Average bus duration 62h 4m |
Cheapest ticket price $263 (€211) |
Buses per day 1 |
Fastest bus 90h 10m |
First bus 02:00 |
Last bus 20:00 |
Bus providers: Greyhound, FlixBus, Jefferson Lines from Des Moines, IA to Portland, ORYou can travel by bus between Des Moines, IA to Portland, OR with Greyhound, FlixBus, Jefferson Lines for as low as $142 (€114). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
Jefferson Lines
FAQs: Bus from Des Moines, IA to Portland, OR
Find answers to the most common questions about traveling from Des Moines, IA to Portland, OR by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Portland, OR, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Portland Japanese Garden, a tranquil 12-acre garden offering traditional Japanese landscaping and cultural events
- Powell's City of Books, the world's largest independent bookstore spanning an entire city block
- Washington Park, a large urban park featuring a zoo, rose garden, and hiking trails
- Pittock Mansion, a historic house museum with panoramic views of Portland and the surrounding mountains
- Lan Su Chinese Garden, a classical Chinese garden in the heart of the city showcasing authentic design and architecture.
- Portland Art Museum, a prominent museum showcasing diverse art collections and rotating exhibitions
- Voodoo Doughnut, a quirky doughnut shop famous for its creative and unconventional doughnut flavors
- Forest Park, one of the largest urban forests in the U. S. Offering extensive hiking and biking trails
- OMSI (Oregon Museum of Science and Industry), an interactive science museum with exhibits and a planetarium
- Portland Saturday Market, a vibrant open-air market featuring local artisans, food vendors, and live entertainment.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Des Moines, IA to Portland, OR, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Des Moines, IA to Portland, OR
Most popular bus connections from Des Moines, IA
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