- Must visit
Portland Art Museum
The city’s leading art museum, known for Native American art, Northwest works, and major traveling exhibitions in a central downtown location.
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The cheapest and fastest buses from Des Moines, IA to Portland, OR
Showing times and prices for May 19
Cheapest price
$271
Average price
$271
Fastest journey
2 d 15 h 40 m
Average duration
2 d 15 h 40 m
Buses per day
1
Distance
2369 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Portland, OR is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Portland, OR will cost around $271 if you buy it on the day, but the cheapest tickets can be found for only $271.
Fast buses
Of the 1 buses that leave Des Moines, IA for Portland, OR on Tue, May 19, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 19 the direct buses cover the 2369 km distance in an average of 2 d 15 h 40 m but if you time it right, some buses will get you there in just 2 d 15 h 40 m .
On Tue, May 19 the slowest buses will take 2 d 15 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:15 AM63h40Des Moines, IA3:55 PMPortland, OR$2711One-way0 transfers
- 12:15 AM63h40Des Moines, IA3:55 PMPortland, OR$2711One-way0 transfers
Travel Information
Compare bus and flight for Des Moines, IA to Portland, OR
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Portland, OR among Omio's users. If you are prioritising price take the bus with prices starting from $233. For those with little time consider booking a flight which can get you there in 5h 39m. The ticket price range depends on the travel mode: a bus costs an average of $233, and a flight costs an average of $201.
Distance: 1472 miles (2369 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$276 Average price Cheapest | $476 Average price | $363 Average price (fuel + tolls) |
72h 55m Average total duration 72h 25m Onboard + 30m Additional time* | 8h 39m Average total duration Fastest 5h 39m Onboard + 3h 0m Additional time* | 26h 3m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Des Moines, IA to Portland, OR is a bus with an average price of $276 (€223).
This is compared to other travel options from Des Moines, IA to Portland, OR:
A bus is $200 (€162) less than a flight for this route with tickets for a flight from Des Moines, IA to Portland, OR costing on average $476 (€384).
The fastest way to travel from Des Moines, IA to Portland, OR is by flight with an average journey time of 5h 39m.
Other travel options to Portland, OR take longer:
Bus takes on average 72h 25m.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Portland, OR including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Portland, OR among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Des Moines, IA to Portland, OR Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 03:55PM | Duration 63h40 | Departure days Mon, Tue, Wed, Sun | Cheapest price $257 |
Operator Greyhound | Departure Time 12:35AM | Arrival Time 04:45AM | Duration 52h10 | Departure days Wed, Fri, Sat | Cheapest price $282 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 05:45AM | Duration 52h30 | Departure days Wed, Sat | Cheapest price $233 |
Operator Jefferson Lines | Departure Time 11:30PM | Arrival Time 08:25PM | Duration 68h55 | Departure days Wed | Cheapest price $638 |
Live departures
Des Moines, IA to Portland, OR bus times
The table below shows live departures for Des Moines, IA to Portland, OR buses for tomorrow, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:15 AM Des Moines, IA | 63h40 | 3:55 PM Portland, OR | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Portland, OR by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 18
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May 19
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Why should you book Des Moines, IA to Portland, OR buses with Omio?
Greyhound as well as Jefferson Lines offer buses services from Des Moines, IA to Portland, OR.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Portland, OR.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Jefferson Lines to find the best option for your trip from Des Moines, IA to Portland, OR.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Portland, OR.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Portland, OR.
Journey information
Overview: Bus from Des Moines, IA to Portland, OR
USAUSA
Buses from Des Moines, IA to Portland, OR run on average 1 times per day, taking around 72h 25m. Cheap bus tickets for this journey start at $233 (€188) but you can travel from only $201 (€162) by flight.
The earliest bus runs at 02:00, the last at 20:00. The fastest bus covers the 1472 miles (2369 km) distance in 52h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $201 (€162)
Distance 1472 miles (2369 km) |
Average bus duration 72h 25m |
Cheapest ticket price $233 (€188) |
Buses per day 1 |
Fastest bus 52h 10m |
First bus 2:00 AM |
Last bus 8:00 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $201 (€162)
Bus providers: Greyhound, Jefferson Lines from Des Moines, IA to Portland, ORYou can travel by bus between Des Moines, IA to Portland, OR with Greyhound, Jefferson Lines for as low as $201 (€162). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
52h 10m
Cheapest Price
$233 (€188)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Jefferson Lines
Luggage & cancellation policy
Average Duration
68h 55m
Cheapest Price
$638 (€515)
Jefferson Lines frequency
1 a day
Complete guide to Portland
Things to do in Portland
Discover the best of Portland — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Portland trip today.
- Must visit
Oregon Museum of Science and Industry
A large hands-on science museum on the Willamette River with interactive exhibits, a planetarium, and family-friendly displays.
- Recommended
Pittock Mansion
A historic house museum with preserved interiors and exhibits about Portland history, plus sweeping views over the city and mountains.
- Must visit
Washington Park
A major urban park combining gardens, trails, memorials, and viewpoints, making it one of Portland’s essential outdoor destinations.
- Must visit
Tom McCall Waterfront Park
A central riverside park popular for walks, bridges views, festivals, and skyline photos along the Willamette.
- Must visit
Lan Su Chinese Garden
A serene walled garden in Old Town that blends architecture, landscaping, and classical Chinese design in a compact city setting.
- Vegetarian
- Vegan
Craft Beer
Portland is one of America’s best-known beer cities, with a deep culture of independent breweries and a wide range of IPA, lager, sour, and stout styles.
- Vegetarian
- Vegan
- Gluten-free
Third-Wave Coffee
Portland has a major specialty coffee scene centered on carefully sourced beans and precise brewing, making local roasters and cafes a core part of the city’s food identity.
- Vegetarian
Voodoo Doughnuts
Playful, oversized doughnuts became a signature Portland treat, known for creative toppings and the city’s quirky food culture.
Le Pigeon
A celebrated Portland restaurant known for inventive French-inspired cooking, rich flavors, and a lively intimate dining room.
Screen Door Eastside
A popular spot for Southern comfort food with a Portland following, especially known for fried chicken and hearty brunch plates.
Deschutes Brewery Portland Public House
A well-known brewery venue serving Oregon craft beer, pub fare, and a spacious relaxed setting in central Portland.
United States Dollar
Moderate by U.S. city standards. Food and coffee are reasonable, but hotels and fine dining can be pricey in central areas.
Average meal costs
- Budget
- USD 10-18 for food carts or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person before drinks and tip.
- Coffee
- USD 4-7 for a coffee drink.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5 as appropriate.
FAQs: Bus from Des Moines, IA to Portland, OR
Find answers to the most common questions about traveling from Des Moines, IA to Portland, OR by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Portland, OR, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Des Moines, IA to Portland, OR can start from as little as $233 (€188) when you book in advance. The average bus ticket price for Des Moines, IA to Portland, OR is $276 (€223) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Portland, OR is 52h 10m to travel the 1472 miles (2369 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Portland, OR leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Portland, OR leaves at 8:00 PM.
There are 1 buses a day from Des Moines, IA to Portland, OR which require at least one change with Greyhound, Jefferson Lines. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Portland, OR, you can count on Greyhound, Jefferson Lines for the best way to get you to Portland, OR. You can also check all possible bus companies who offer a service between Des Moines, IA and Portland, OR and compare the amenities they offer before buying a bus ticket.
A trip to Portland, OR from Des Moines, IA is worth doing but not as a day trip with a journey time of 52h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Portland, OR is February.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Portland, OR including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Portland, OR:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Portland, OR for bus company Greyhound.
Some of the most interesting sights to explore in Portland, OR are:
- Portland Japanese Garden, a tranquil 12-acre garden offering traditional Japanese landscaping and cultural events
- Powell's City of Books, the world's largest independent bookstore spanning an entire city block
- Washington Park, a large urban park featuring a zoo, rose garden, and hiking trails
- Pittock Mansion, a historic house museum with panoramic views of Portland and the surrounding mountains
- Lan Su Chinese Garden, a classical Chinese garden in the heart of the city showcasing authentic design and architecture.
The best things to do in Portland, OR include:
- Portland Art Museum, a prominent museum showcasing diverse art collections and rotating exhibitions
- Voodoo Doughnut, a quirky doughnut shop famous for its creative and unconventional doughnut flavors
- Forest Park, one of the largest urban forests in the U.S., offering extensive hiking and biking trails
- OMSI (Oregon Museum of Science and Industry), an interactive science museum with exhibits and a planetarium
- Portland Saturday Market, a vibrant open-air market featuring local artisans, food vendors, and live entertainment.
Whether you can cancel your bus ticket from Des Moines, IA to Portland, OR depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Portland, OR.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Portland, OR:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Portland, OR:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Portland, OR.
You can reserve your seat on the bus from Des Moines, IA to Portland, OR with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Portland, OR with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Portland, OR with the following bus company: Greyhound.
Since neither Des Moines, IA nor Portland, OR are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Portland, OR among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Portland, OR, travelers should be cautious of pickpocketing and occasional vehicle break-ins, especially in crowded areas and popular tourist spots. Scams involving fake ticket sellers and unauthorized ride services have been reported, so it’s best to use official transportation providers and purchase tickets through reputable sources. Staying aware of surroundings and securing belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Des Moines, IA to Portland, OR
Des Moines
Portland
Portland, NW Station Way (Station Place Parking Garage)
information
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Portland, OR
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Most popular buses to and from Portland, OR and Des Moines, IA
Most popular bus connections to Portland, OR
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