Des Moines, IA to Portland, OR bus with Greyhound

Wed, Sep 30
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to Portland, OR

Showing times, prices and bookable tickets for Sep 30

Cheapest price on Sep 30

$622

Average ticket price on Sep 30

$622

Fastest journey on Sep 30

2 d 20 h 55 m

Average journey duration on Sep 30

2 d 20 h 55 m

Buses on Sep 30

1

Distance

2369 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Portland, OR is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Portland, OR will cost around $622 if you buy it on the day, but the cheapest tickets can be found for only $622.

Fast buses

It's difficult to get from Des Moines, IA to Portland, OR without transferring at least 4 times.

  • Jefferson Lines
    11:30 PM68h55
    Des Moines, IA
    8:25 PMPortland, OR
    $6221One-way
    4 transfers

Des Moines, IA to Portland, OR Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:15AM
Arrival Time
03:55PM
Duration
63h40
Departure days
Mon, Tue, Wed, Sun
Cheapest price
$251
Operator
Greyhound
Departure Time
12:35AM
Arrival Time
04:45AM
Duration
52h10
Departure days
Wed, Fri, Sat
Cheapest price
$275
Operator
Greyhound
Departure Time
01:15AM
Arrival Time
05:45AM
Duration
52h30
Departure days
Wed, Sat
Cheapest price
$228
Operator
Jefferson Lines
Departure Time
11:30PM
Arrival Time
08:25PM
Duration
68h55
Departure days
Wed
Cheapest price
$622

Live departures

Des Moines, IA to Portland, OR bus times

The table below shows live departures for Des Moines, IA to Portland, OR buses for tomorrow, Wednesday, September 30. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Jefferson Lines11:30 PM Des Moines, IA
68h55
8:25 PM Portland, OR4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Portland, OR by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Des Moines, IA to Portland, OR buses with Omio?

Greyhound operates all buses services from Des Moines, IA to Portland, OR.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Portland, OR.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Portland, OR.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Portland, OR.

Journey information

Overview: Bus from Des Moines, IA to Portland, OR

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to Portland, OR run on average 1 times per day, taking around 49h 25m. Cheap bus tickets for this journey start at $278 (€230) but you can travel from only $192 (€159) by flight.

The earliest bus runs at 02:00, the last at 20:00. The fastest bus covers the 1472 miles (2369 km) distance in 49h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $192 (€159)
Distance
1472 miles (2369 km)
Average bus duration
49h 25m
Cheapest ticket price
$278 (€230)
Buses per day
1
Fastest bus
49h 25m
First bus
2:00 AM
Last bus
8:00 PM
Cheapest Month
Feb
Cheapest Day
Sun
High Season
Jul - Sep
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $192 (€159)

Bus providers: Greyhound from Des Moines, IA to Portland, ORYou can travel by bus between Des Moines, IA to Portland, OR with Greyhound for as low as $192 (€159). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
49h 25m
Cheapest Greyhound Price
$278 (€230)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Portland, OR

Things to do in Portland, OR

Discover the best of Portland, OR — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Portland, OR trip today.

  • Must visit

Portland Art Museum

World-class collections spanning Native American, Asian, and Northwest art. A cornerstone cultural stop in the South Park Blocks.

  • Must visit

OMSI

Hands-on museum famed for the USS Blueback submarine, science labs, and family-friendly exhibits on technology and nature.

  • Recommended

Movie Madness Museum

Eclectic museum of movie props, oddities, and outsider collections in Northwest Portland. Fun, quirky, and uniquely local.

U.S. dollar ($)

Moderate for U.S. city travel: hotels and dining are mid-priced, transit is reasonable, and budget food is easy to find.

Average meal costs

Budget
$10-18 for fast food or casual eats.
Mid-range
$20-40 per person for a restaurant meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$4-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, more for great service. Taxis: 10-15%. Cafes: round up or tip $1-2 for drinks.

FAQs: Bus from Des Moines, IA to Portland, OR

Find answers to the most common questions about traveling from Des Moines, IA to Portland, OR by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Portland, OR, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Portland, OR can start from as little as $278 (€230) when you book in advance. The average bus ticket price for Des Moines, IA to Portland, OR is $289 (€239) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Portland, OR is 49h 25m to travel the 1472 miles (2369 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Portland, OR leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Portland, OR leaves at 8:00 PM.
There are 1 buses a day from Des Moines, IA to Portland, OR which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Portland, OR, you can count on Greyhound for the best way to get you to Portland, OR. You can also check all possible bus companies who offer a service between Des Moines, IA and Portland, OR and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA, which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Portland, NW Station Way (Station Place Parking Garage), OR, located 0 away from the city centre.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Portland, OR including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Portland, OR:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Portland, OR for bus company Greyhound.
Whether you can cancel your bus ticket from Des Moines, IA to Portland, OR depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Portland, OR.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Portland, OR:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Portland, OR:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Portland, OR.
You can reserve your seat on the bus from Des Moines, IA to Portland, OR with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Portland, OR with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Portland, OR with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Portland, OR, travelers should be cautious of pickpocketing and occasional vehicle break-ins, especially in crowded areas and popular tourist spots. Scams involving fake ticket sellers and unauthorized ride services have been reported, so it’s best to use official transportation providers and purchase tickets through reputable sources. Staying aware of surroundings and securing belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Des Moines, IA to Portland, OR

Most Des Moines, IA to Portland, OR buses use the Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) to Portland, NW Station Way (Station Place Parking Garage) station pair. Use this guide to compare Des Moines, IA and Portland, OR bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Des Moines
Arrival bus stations in Portland

Which Des Moines, IA station do buses to Portland, OR leave from?

Buses from Des Moines, IA to Portland, OR leave from Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). The station is 1 miles (3 km) from Des Moines, IA city centre at 1625 E Euclid Ave, Des Moines, IA 50313, USA.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.)1625 E Euclid Ave, Des Moines, IA 50313, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) from Des Moines city centre

Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:

TRUE

Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) bus station facilities and services

Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).

Tickets and information

Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).

Parking, taxis and toilets

Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.

More options for your journey from Des Moines, IA to Portland, OR

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Portland, ORDes Moines, IA to Portland, OR bus

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