- Must visit
Portland Art Museum
World-class collections spanning Native American, Asian, and Northwest art. A cornerstone cultural stop in the South Park Blocks.
Cheapest price
$260
Average price
$260
Fastest journey
2 d 15 h 40 m
Average duration
2 d 15 h 40 m
Buses per day
1
Distance
2369 km
The best way to find a cheap bus ticket from Des Moines, IA to Portland, OR is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Portland, OR will cost around $260 if you buy it on the day, but the cheapest tickets can be found for only $260.
Of the 1 buses that leave Des Moines, IA for Portland, OR on Sat, Aug 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Aug 22 the direct buses cover the 2369 km distance in an average of 2 d 15 h 40 m but if you time it right, some buses will get you there in just 2 d 15 h 40 m .
On Sat, Aug 22 the slowest buses will take 2 d 15 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Portland, OR among Omio's users. If you are prioritising price take the bus with prices starting from $232. For those with little time consider booking a flight which can get you there in 5h 39m. The ticket price range depends on the travel mode: a bus costs an average of $232, and a flight costs an average of $200.
Distance: 1472 miles (2369 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$275 Average price Cheapest | $474 Average price | $361 Average price (fuel + tolls) |
72h 55m Average total duration 72h 25m Onboard + 30m Additional time* | 8h 39m Average total duration Fastest 5h 39m Onboard + 3h 0m Additional time* | 26h 3m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Portland, OR:
A bus is $199 (€162) less than a flight for this route with tickets for a flight from Des Moines, IA to Portland, OR costing on average $474 (€384).
Other travel options to Portland, OR take longer:
Bus takes on average 72h 25m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 03:55PM | Duration 63h40 | Departure days Mon, Tue, Wed, Sun | Cheapest price $256 |
Operator Greyhound | Departure Time 12:35AM | Arrival Time 04:45AM | Duration 52h10 | Departure days Wed, Fri, Sat | Cheapest price $280 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 05:45AM | Duration 52h30 | Departure days Wed, Sat | Cheapest price $232 |
Operator Jefferson Lines | Departure Time 11:30PM | Arrival Time 08:25PM | Duration 68h55 | Departure days Wed | Cheapest price $635 |
The table below shows live departures for Des Moines, IA to Portland, OR buses for tomorrow, Sunday, August 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:15 AM Des Moines, IA | 63h40 | 3:55 PM Portland, OR | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Portland, OR run on average 1 times per day, taking around 72h 25m. Cheap bus tickets for this journey start at $232 (€188) but you can travel from only $200 (€162) by flight.
The earliest bus runs at 02:00, the last at 20:00. The fastest bus covers the 1472 miles (2369 km) distance in 52h 10m.
Distance 1472 miles (2369 km) |
Average bus duration 72h 25m |
Cheapest ticket price $232 (€188) |
Buses per day 1 |
Fastest bus 52h 10m |
First bus 2:00 AM |
Last bus 8:00 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Discover the best of Portland, OR — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Portland, OR trip today.
World-class collections spanning Native American, Asian, and Northwest art. A cornerstone cultural stop in the South Park Blocks.
Hands-on museum famed for the USS Blueback submarine, science labs, and family-friendly exhibits on technology and nature.
Eclectic museum of movie props, oddities, and outsider collections in Northwest Portland. Fun, quirky, and uniquely local.
A 165-acre woodland park with serene paths, a rose garden, and Japanese Garden access. One of Portland's signature green spaces.
Beloved downtown square known as Portland's living room. Hosts events, people-watching, and easy access to major central sights.
Large urban forest with miles of trails for hiking and running. A local favorite for quick immersion in nature near downtown.
A toasted bread ring with a malty crust and chewy center. Portland shops helped make the city's bagel scene a modern local obsession.
Traditional regional chowder from the Pacific Northwest, usually with local clams, cream, potatoes, and herbs. A staple on many Portland seafood menus.
Fresh oysters from the Oregon coast, prized for their briny, clean flavor. Portland is a major city showcase for the state's shellfish culture.
Acclaimed bagel shop serving naturally leavened bagels with classic toppings in a casual neighborhood space.
Pioneering specialty coffee roaster with expertly brewed coffee and a minimalist café atmosphere loved by locals.
Iconic Portland brewery and pub pouring house beers with hearty pub fare in a lively, long-running local setting.
Moderate for U.S. city travel: hotels and dining are mid-priced, transit is reasonable, and budget food is easy to find.
Tip 18-20% at restaurants, more for great service. Taxis: 10-15%. Cafes: round up or tip $1-2 for drinks.
Find answers to the most common questions about traveling from Des Moines, IA to Portland, OR by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Portland, OR, this guide helps you travel smarter and with confidence.

Most Des Moines, IA to Portland, OR buses use the Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) to Portland, NW Station Way (Station Place Parking Garage) station pair. Use this guide to compare Des Moines, IA and Portland, OR bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Portland, NW Station Way (Station Place Parking Garage) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Portland, NW Station Way (Station Place Parking Garage). ATMs are available at Portland, NW Station Way (Station Place Parking Garage).
Ticket office support is available at Portland, NW Station Way (Station Place Parking Garage).
Available at Portland, NW Station Way (Station Place Parking Garage): Parking, Taxis, WC.
Accessibility facilities are available at Portland, NW Station Way (Station Place Parking Garage): Ramp access available.
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