St. Louis, MO to Milwaukee, WI bus with FlixBus

Sat, Sep 19
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2,000+ travel companies
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The cheapest and fastest buses from St. Louis, MO to Milwaukee, WI

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

kr422

Average ticket price on Sep 19

kr441

Fastest journey on Sep 19

8 h 25 m

Average journey duration on Sep 19

9 h 19 m

Buses on Sep 19

6

Distance

527 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to Milwaukee, WI is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Milwaukee, WI will cost around kr441 if you buy it on the day, but the cheapest tickets can be found for only kr422.

Fast buses

It's difficult to get from St. Louis, MO to Milwaukee, WI without transferring at least once.

  • FlixBusFlixBus · FlixBus
    10:00 AM8h25
    St. Louis, S 15th St (Civic center)
    6:25 PMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI
    kr4221One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    11:30 PM11h05
    St. Louis, S 15th St (Civic center)
    10:35 AMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI
    kr4221One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    10:00 AM8h45
    St. Louis, S 15th St (Civic center)
    6:45 PMMilwaukee, Intermodal Station
    kr4301One-way
    1 transfer
  • FlixBusFlixBus+Greyhound
    11:30 PM9h00
    St. Louis, S 15th St (Civic center)
    8:30 AMMilwaukee, Intermodal Station
    kr4301One-way
    1 transfer
  • FlixBusFlixBus+Greyhound
    2:30 PM9h20
    St. Louis, S 15th St (Civic center)
    11:50 PMMilwaukee, Intermodal Station
    kr4421One-way
    1 transfer

Travel Information

Compare bus, train, and flight for St. Louis, MO to Milwaukee, WI

Omio recommends booking the train as it is the most popular option from St. Louis, MO to Milwaukee, WI among Omio's users. If you are prioritising price, take the bus, with an average ticket price of kr531 For those with little time, consider booking a flight, which has an average total journey time of 5h 51m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of kr531, while a flight costs an average of kr4066.

Distance: 327 miles (527 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

kr531

Average price

Cheapest

kr1109

Average price

kr4066

Average price

kr531

Average price

(fuel + tolls)

9h 21m

Average total duration

8h 51m

Onboard

+

30m

Additional time*

7h 19m

Average total duration

6h 49m

Onboard

+

30m

Additional time*

5h 51m

Average total duration

Fastest

3h 51m

Onboard

+

2h 0m

Additional time*

5h 17m

Average total duration

(door-to-door)

0.5 - 1.3kg

CO2 emissions

0.2 - 0.5kg

CO2 emissions

Lowest

1.6 - 3.2kg

CO2 emissions

-

CO2 emissions

FlixBus

Most popular bus company

Amtrak

Most popular train company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from St. Louis, MO to Milwaukee, WI is a bus with an average price of kr531.

This is compared to other travel options from St. Louis, MO to Milwaukee, WI:

A bus is kr578 less than a train for this route with tickets for a train from St. Louis, MO to Milwaukee, WI costing on average kr1109.

A bus is kr3535 less than a flight for this route with tickets for a flight from St. Louis, MO to Milwaukee, WI costing on average kr4066.

The fastest way to travel from St. Louis, MO to Milwaukee, WI is by flight with an average journey time of 3h 51m.

Other travel options to Milwaukee, WI take longer:

Train takes on average 6h 49m.

Bus takes on average 8h 51m.

It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Milwaukee, WI including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to Milwaukee, WI among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around kr531 compared to roughly kr531 in fuel and tolls — a saving of about kr-0.16. The journey takes 8h 51m versus 5h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

St. Louis, MO to Milwaukee, WI Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
02:00AM
Arrival Time
05:00PM
Duration
15h00
Departure days
Everyday
Cheapest price
kr382
Operator
Greyhound
Departure Time
08:45AM
Arrival Time
11:50PM
Duration
15h05
Departure days
Wed, Thu
Cheapest price
kr369
Operator
FlixBus
Departure Time
10:00AM
Arrival Time
06:45PM
Duration
8h45
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
kr370
Operator
FlixBus
Departure Time
02:30PM
Arrival Time
11:50PM
Duration
9h20
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
kr394
Operator
FlixBus
Departure Time
04:00PM
Arrival Time
02:10AM
Duration
10h10
Departure days
Tue, Wed, Thu, Sun
Cheapest price
kr369
Operator
FlixBus
Departure Time
11:30PM
Arrival Time
08:30AM
Duration
9h00
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
kr365

Live departures

St. Louis, MO to Milwaukee, WI bus times

The table below shows live departures for St. Louis, MO to Milwaukee, WI buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus10:00 AM St. Louis, S 15th St (Civic center)
8h45
6:45 PM Milwaukee, Intermodal Station1 transfer
FlixBusFlixBus · FlixBus10:00 AM St. Louis, S 15th St (Civic center)
8h25
6:25 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI1 transfer
FlixBusFlixBus+Greyhound2:30 PM St. Louis, S 15th St (Civic center)
9h20
11:50 PM Milwaukee, Intermodal Station1 transfer
FlixBusFlixBus+Greyhound11:30 PM St. Louis, S 15th St (Civic center)
9h00
8:30 AM Milwaukee, Intermodal Station1 transfer
FlixBusFlixBus · FlixBus11:30 PM St. Louis, S 15th St (Civic center)
11h05
10:35 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI1 transfer
Greyhound · · 2:00 AM St. Louis, S 15th St (Civic center)
15h00
5:00 PM Milwaukee, Intermodal Station2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Milwaukee, WI by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
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Sep 22
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Sep 23
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Sep 25

Why should you book St. Louis, MO to Milwaukee, WI buses with Omio?

Greyhound as well as FlixBus offer buses services from St. Louis, MO to Milwaukee, WI.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Milwaukee, WI.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Milwaukee, WI.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Milwaukee, WI.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Milwaukee, WI.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Milwaukee, WI.

Journey information

Overview: Bus from St. Louis, MO to Milwaukee, WI

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to Milwaukee, WI run on average 6 times per day, taking around 8h 51m. Cheap bus tickets for this journey start at kr247 if you book in advance.

The earliest bus runs at 01:55, the last at 23:30. The fastest bus covers the 327 miles (527 km) distance in 7h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
327 miles (527 km)
Average bus duration
8h 51m
Cheapest ticket price
kr247
Buses per day
6
Fastest bus
7h 0m
First bus
1:55 AM
Last bus
11:30 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Mon
Least Busy Day
Fri
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from St. Louis, MO to Milwaukee, WIYou can travel by bus between St. Louis, MO to Milwaukee, WI with FlixBus, Greyhound for as low as kr247. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
7h 0m
Cheapest FlixBus Price
kr247
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
10h 15m
Cheapest Greyhound Price
kr290
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Milwaukee, WI

Things to do in Milwaukee, WI

Discover the best of Milwaukee, WI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milwaukee, WI trip today.

  • Must visit

Milwaukee Art Museum

Leading lakefront museum with strong decorative arts, American art, and iconic architecture. It is Milwaukee's signature cultural attraction.

  • Must visit

Discovery World

Science and technology museum with hands-on exhibits, a dome theater, and major industrial displays. Great for families and curious adults alike.

  • Must visit

Milwaukee Public Museum

Large natural and human history museum with dinosaur fossils, the Streets of Old Milwaukee, and cultural collections. A classic city institution.

United States Dollar ($)

Moderate for U.S. city breaks: hotels are often cheaper than Chicago, dining is mid-priced, and local transit is limited so visitors may spend more on rideshares or parking.

Average meal costs

Budget
$10-15 for fast food or casual lunch.
Mid-range
$20-40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale dining.
Coffee
$3-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% in restaurants, more for excellent service. Round up or tip about 10% for taxis. Cafes often use tip jars or screens; $1-2 or 10-15% is common.

FAQs: Bus from St. Louis, MO to Milwaukee, WI

Find answers to the most common questions about traveling from St. Louis, MO to Milwaukee, WI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milwaukee, WI, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to Milwaukee, WI can start from as little as kr247 when you book in advance. The average bus ticket price for St. Louis, MO to Milwaukee, WI is kr531 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Milwaukee, WI is 7h 0m to travel the 327 miles (527 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Milwaukee, WI leaves at 1:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Milwaukee, WI leaves at 11:30 PM.
There are 6 buses a day from St. Louis, MO to Milwaukee, WI which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Milwaukee, WI, you can count on Greyhound, FlixBus for the best way to get you to Milwaukee, WI. You can also check all possible bus companies who offer a service between St. Louis, MO and Milwaukee, WI and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center) . When arriving in Milwaukee, WI , you can end your journey in bus stations like Milwaukee, Intermodal Station, Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI, Brookfield, North Barker Road (Goerke's Corners Park & Ride), WI .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Milwaukee, Intermodal Station, located 1 away from the city centre.
A trip to Milwaukee, WI from St. Louis, MO is worth doing but not as a day trip with a journey time of 7h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Milwaukee, WI is February.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Milwaukee, WI including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Milwaukee, WI for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Milwaukee, WI:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Whether you can cancel your bus ticket from St. Louis, MO to Milwaukee, WI depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Milwaukee, WI.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Milwaukee, WI:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Milwaukee, WI:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Milwaukee, WI. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Milwaukee, WI with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Milwaukee, WI with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Milwaukee, WI with the following bus company: Greyhound, FlixBus.
Since neither St. Louis, MO nor Milwaukee, WI are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Milwaukee, WI among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Milwaukee, WI, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like festivals and public transit. Avoid displaying valuables openly and stay aware of your surroundings. Common scams include overcharging by taxi or rideshare drivers and fake ticket sales for events. It’s advisable to use reputable transportation services and purchase tickets from official sources. Staying in well-lit, populated areas at night enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from St. Louis, MO to Milwaukee, WI

Most St. Louis, MO to Milwaukee, WI buses use the St. Louis, S 15th St (Civic center) to Milwaukee, Intermodal Station station pair, with some services arriving at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). Use this guide to compare St. Louis, MO and Milwaukee, WI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in Milwaukee

Which St. Louis, MO station do buses to Milwaukee, WI leave from?

Buses from St. Louis, MO to Milwaukee, WI leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · kr24 · every ~14 min
Bus19, 32, 40 · 8m · kr8 · every ~9 min

St. Louis, S 15th St (Civic center) bus station facilities and services

St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).

Tickets and information

Ticket office support is available at St. Louis, S 15th St (Civic center).

Parking, taxis and toilets

Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.

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