- Must visit
Milwaukee Art Museum
Major lakeside art museum known for its Santiago Calatrava-designed Quadracci Pavilion and strong American and decorative arts collections.
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The cheapest and fastest buses from St. Louis, MO to Milwaukee, WI
Showing times and prices for Jun 20
Cheapest price
$101
Average price
$104
Fastest journey
8 h 25 m
Average duration
9 h 29 m
Buses per day
6
Distance
527 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Milwaukee, WI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Milwaukee, WI will cost around $104 if you buy it on the day, but the cheapest tickets can be found for only $101.
Fast buses
It's difficult to get from St. Louis, MO to Milwaukee, WI without transferring at least once.
FlixBus · FlixBus11:30 PM11h05St. Louis, S 15th St (Civic center)10:35 AMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI$1011One-way1 transfer- FlixBus · FlixBus10:00 AM8h25St. Louis, S 15th St (Civic center)6:25 PMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI$1011One-way1 transfer
- FlixBus+
11:30 PM9h00St. Louis, S 15th St (Civic center)8:30 AMMilwaukee, Intermodal Station$1021One-way1 transfer - FlixBus · FlixBus10:00 AM8h45St. Louis, S 15th St (Civic center)6:45 PMMilwaukee, Intermodal Station$1021One-way1 transfer
- · · 2:00 AM14h50St. Louis, S 15th St (Civic center)4:50 PMMilwaukee, Intermodal Station$1071One-way2 transfers
- FlixBus · FlixBus10:00 AM8h25St. Louis, S 15th St (Civic center)6:25 PMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI$1011One-way1 transfer
- FlixBus · FlixBus10:00 AM8h45St. Louis, S 15th St (Civic center)6:45 PMMilwaukee, Intermodal Station$1021One-way1 transfer
- FlixBus+11:30 PM9h00St. Louis, S 15th St (Civic center)8:30 AMMilwaukee, Intermodal Station$1021One-way1 transfer
- FlixBus+4:00 PM10h10St. Louis, S 15th St (Civic center)2:10 AMMilwaukee, Intermodal Station$1101One-way1 transfer
- FlixBus · FlixBus11:30 PM11h05St. Louis, S 15th St (Civic center)10:35 AMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI$1011One-way1 transfer
Travel Information
Compare bus, train, and flight for St. Louis, MO to Milwaukee, WI
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Milwaukee, WI among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 5h 26m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $106.
Distance: 327 miles (527 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$90 Average price Cheapest | $100 Average price | $283 Average price | $80 Average price (fuel + tolls) |
8h 17m Average total duration 7h 47m Onboard + 30m Additional time* | 6h 59m Average total duration 6h 29m Onboard + 30m Additional time* | 8h 26m Average total duration Fastest 5h 26m Onboard + 3h 0m Additional time* | 5h 17m Average total duration (door-to-door) |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from St. Louis, MO to Milwaukee, WI is a bus with an average price of $90 (€74).
This is compared to other travel options from St. Louis, MO to Milwaukee, WI:
A bus is $10 (€8) less than a train for this route with tickets for a train from St. Louis, MO to Milwaukee, WI costing on average $100 (€82).
A bus is $193 (€158) less than a flight for this route with tickets for a flight from St. Louis, MO to Milwaukee, WI costing on average $283 (€232).
The fastest way to travel from St. Louis, MO to Milwaukee, WI is by flight with an average journey time of 5h 26m.
Other travel options to Milwaukee, WI take longer:
Train takes on average 6h 29m.
Bus takes on average 7h 47m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Milwaukee, WI including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Milwaukee, WI among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
St. Louis, MO to Milwaukee, WI Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 04:50PM | Duration 14h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $59 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 03:35PM | Duration 11h05 | Departure days Wed | Cheapest price $118 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 06:45PM | Duration 8h45 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 04:45AM | Duration 13h45 | Departure days Tue | Cheapest price $74 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 02:10AM | Duration 10h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 10:35AM | Duration 11h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $53 |
Live departures
St. Louis, MO to Milwaukee, WI bus times
The table below shows live departures for St. Louis, MO to Milwaukee, WI buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 10:00 AM St. Louis, S 15th St (Civic center) | 8h45 | 6:45 PM Milwaukee, Intermodal Station | 1 transfer | |
| FlixBus · FlixBus | 10:00 AM St. Louis, S 15th St (Civic center) | 8h25 | 6:25 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 1 transfer | |
| FlixBus+ | 4:00 PM St. Louis, S 15th St (Civic center) | 10h10 | 2:10 AM Milwaukee, Intermodal Station | 1 transfer | |
| FlixBus · FlixBus | 11:30 PM St. Louis, S 15th St (Civic center) | 11h05 | 10:35 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 1 transfer | |
| FlixBus+ | 11:30 PM St. Louis, S 15th St (Civic center) | 9h00 | 8:30 AM Milwaukee, Intermodal Station | 1 transfer | |
| · · | 2:00 AM St. Louis, S 15th St (Civic center) | 14h50 | 4:50 PM Milwaukee, Intermodal Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Milwaukee, WI by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Milwaukee, WI buses with Omio?
Greyhound as well as FlixBus offer buses services from St. Louis, MO to Milwaukee, WI.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Milwaukee, WI.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Milwaukee, WI.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Milwaukee, WI.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Milwaukee, WI.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Milwaukee, WI.
Journey information
Overview: Bus from St. Louis, MO to Milwaukee, WI
USAUSA
Buses from St. Louis, MO to Milwaukee, WI run on average 6 times per day, taking around 7h 47m. Cheap bus tickets for this journey start at $51 (€42) if you book in advance.
The earliest bus runs at 01:55, the last at 23:30. The fastest bus covers the 327 miles (527 km) distance in 8h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 327 miles (527 km) |
Average bus duration 7h 47m |
Cheapest ticket price $51 (€42) |
Buses per day 6 |
Fastest bus 8h 45m |
First bus 1:55 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 63 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from St. Louis, MO to Milwaukee, WIYou can travel by bus between St. Louis, MO to Milwaukee, WI with Greyhound, FlixBus for as low as $51 (€42). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
8h 45m
Cheapest Price
$54 (€45)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
14h 45m
Cheapest Price
$51 (€42)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Milwaukee
Things to do in Milwaukee
Discover the best of Milwaukee — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milwaukee trip today.
- Must visit
Harley-Davidson Museum
Flagship museum telling the story of Harley-Davidson through historic motorcycles, engines, archives, and interactive exhibits.
- Recommended
Discovery World
Science and technology museum on the lakefront with hands-on exhibits, aquariums, and Great Lakes-focused displays.
- Must visit
Milwaukee RiverWalk
Signature pedestrian route along the Milwaukee River connecting downtown districts, public art, bars, and city views.
- Must visit
Historic Third Ward
Trendy historic warehouse district packed with boutiques, galleries, markets, and photogenic streets popular with visitors.
- Recommended
Lakefront Trail
Scenic walking and cycling path along Lake Michigan with beaches, parks, and classic skyline and water views.
Beer Bratwurst
A Milwaukee classic: bratwurst simmered in beer and onions, then grilled and served on a roll. It reflects the city’s strong German immigrant and brewing heritage.
Friday Fish Fry
A beloved Wisconsin tradition found across Milwaukee, usually featuring battered cod or perch with coleslaw, rye bread, and potato pancakes or fries.
- Vegetarian
Cheese Curds
Fresh or fried curds made from young cheddar cheese. They are one of Wisconsin’s most iconic snacks and a staple on Milwaukee menus and at beer halls.
Sanford
One of Milwaukee’s best-known fine dining restaurants, offering refined seasonal American cuisine in an intimate, polished setting.
Kopp's Frozen Custard
An iconic local stand celebrated for frozen custard and jumbo burgers. A must for a classic Milwaukee dessert stop with a long-standing local following.
Lakefront Brewery Beer Hall
Popular brewery and beer hall famous for fish fry, cheese curds, and local beer. Lively, casual atmosphere that captures Milwaukee’s brewing culture.
United States Dollar
Moderate by U.S. standards. Hotels vary by season, while casual dining, beer, and local transit are fairly affordable.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60+ per person before drinks and tax.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for cafes if desired.
FAQs: Bus from St. Louis, MO to Milwaukee, WI
Find answers to the most common questions about traveling from St. Louis, MO to Milwaukee, WI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milwaukee, WI, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Milwaukee, WI can start from as little as $51 (€42) when you book in advance. The average bus ticket price for St. Louis, MO to Milwaukee, WI is $90 (€74) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Milwaukee, WI is 8h 45m to travel the 327 miles (527 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Milwaukee, WI leaves at 1:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Milwaukee, WI leaves at 11:30 PM.
There are 6 buses a day from St. Louis, MO to Milwaukee, WI which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Milwaukee, WI, you can count on Greyhound, FlixBus for the best way to get you to Milwaukee, WI. You can also check all possible bus companies who offer a service between St. Louis, MO and Milwaukee, WI and compare the amenities they offer before buying a bus ticket.
A trip to Milwaukee, WI from St. Louis, MO is worth doing but not as a day trip with a journey time of 8h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Milwaukee, WI is February.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Milwaukee, WI including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Milwaukee, WI:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Milwaukee, WI for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from St. Louis, MO to Milwaukee, WI depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Milwaukee, WI.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Milwaukee, WI:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Milwaukee, WI:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Milwaukee, WI. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Milwaukee, WI with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Milwaukee, WI with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Milwaukee, WI with the following bus company: FlixBus, Greyhound.
Since neither St. Louis, MO nor Milwaukee, WI are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Milwaukee, WI among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Milwaukee, WI, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like festivals and public transit. Avoid displaying valuables openly and stay aware of your surroundings. Common scams include overcharging by taxi or rideshare drivers and fake ticket sales for events. It’s advisable to use reputable transportation services and purchase tickets from official sources. Staying in well-lit, populated areas at night enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Milwaukee, WI
Most St. Louis, MO to Milwaukee, WI buses use the St. Louis, S 15th St (Civic center) to Milwaukee, Intermodal Station station pair, with some services arriving at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). Use this guide to compare St. Louis, MO and Milwaukee, WI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Milwaukee
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
Milwaukee, Intermodal Station
City-centre transport
Getting to Milwaukee, Intermodal Station from Milwaukee city centre
Bus57 · 4m · $5 · every ~4 min
Wisconsin Coach Lines · 6m · $4
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop)
City-centre transport
Getting to Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) from Milwaukee city centre
BusWisconsin Coach Lines · 10m · $6
Gre · 19m · $4 · every ~8 min
Gre · 27m · $4 · every ~8 min
Gre · 29m · $4 · every ~8 min
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Milwaukee, WI
Here are some other resources that might have the information you need
Most popular buses to and from Milwaukee, WI and St. Louis, MO
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