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The cheapest and fastest buses from Des Moines, IA to Jacksonville, FL
Showing times and prices for May 19
Cheapest price
$348
Average price
$348
Fastest journey
1 d 21 h 40 m
Average duration
1 d 21 h 40 m
Buses per day
1
Distance
1648 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Jacksonville, FL will cost around $348 if you buy it on the day, but the cheapest tickets can be found for only $348.
Fast buses
It's difficult to get from Des Moines, IA to Jacksonville, FL without transferring at least 2 times.
9:20 AM45h40Des Moines, IA7:00 AMJacksonville, FL$3481One-way2 transfers
- 9:20 AM45h40Des Moines, IA7:00 AMJacksonville, FL$3481One-way2 transfers
Travel Information
Compare bus for Des Moines, IA to Jacksonville, FL
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $158. For those with little time consider booking a bus which can get you there in 31h 40m. The ticket price range depends on the travel mode: a bus costs an average of $158, and a bus costs an average of $158.
Distance: 1024 miles (1648 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$184 Average price Cheapest | $244 Average price (fuel + tolls) |
32h 10m Average total duration Fastest 31h 40m Onboard + 30m Additional time* | 18h 30m Average total duration (door-to-door) |
Direct Options | Direct Options |
The cheapest way to travel from Des Moines, IA to Jacksonville, FL is a bus with an average price of $184 (€148).
The fastest way to travel from Des Moines, IA to Jacksonville, FL is by bus with an average journey time of 31h 40m.
Yes, you can take a bus between Des Moines, IA and Jacksonville, FL.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Jacksonville, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Des Moines, IA to Jacksonville, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 09:20AM | Arrival Time 07:00AM | Duration 45h40 | Departure days Tue | Cheapest price $348 |
Operator Greyhound USA | Departure Time 09:45AM | Arrival Time 11:05PM | Duration 37h20 | Departure days Mon, Fri, Sun | Cheapest price $348 |
Operator Greyhound | Departure Time 09:55AM | Arrival Time 05:35PM | Duration 31h40 | Departure days Wed, Thu | Cheapest price $158 |
Live departures
Des Moines, IA to Jacksonville, FL bus times
The table below shows live departures for Des Moines, IA to Jacksonville, FL buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:45 AM Des Moines, IA | 37h20 | 11:05 PM Jacksonville, FL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Jacksonville, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 19
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Why should you book Des Moines, IA to Jacksonville, FL buses with Omio?
Greyhound operates all buses services from Des Moines, IA to Jacksonville, FL.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Jacksonville, FL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Des Moines, IA to Jacksonville, FL
USAUSA
Buses from Des Moines, IA to Jacksonville, FL run on average 1 times per day, taking around 31h 40m. Cheap bus tickets for this journey start at $158 (€128) if you book in advance.
The earliest bus runs at 05:30, the last at 21:25. The fastest bus covers the 1024 miles (1648 km) distance in 31h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1024 miles (1648 km) |
Average bus duration 31h 40m |
Cheapest ticket price $158 (€128) |
Buses per day 1 |
Fastest bus 31h 40m |
First bus 5:30 AM |
Last bus 9:25 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Des Moines, IA to Jacksonville, FLYou can travel by bus between Des Moines, IA to Jacksonville, FL with Greyhound for as low as $158 (€128). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
31h 40m
Cheapest Price
$158 (€128)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Jacksonville
Things to do in Jacksonville
Discover the best of Jacksonville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville trip today.
Museum of Science & History
Focusing on local history, science, and innovation, this museum offers engaging exhibits and a planetarium.
Ritz Theatre and Museum
Located in the historic African American community of LaVilla, it celebrates the heritage and culture of the area's residents.
- Recommended
Five Points
A hip neighborhood known for its eclectic shops, dining, and vibrant nightlife.
- Recommended
San Marco Square
A historic neighborhood with Mediterranean revival architecture, trendy eateries, and shopping.
- Recommended
Atlantic Beach
A charming beach town offering stunning beach views, local eateries, and shops.
Shrimp and Grits
A popular Southern dish featuring shrimp cooked with a savory sauce and served over creamy grits, often seasoned with spices unique to Jacksonville.
- Gluten-free
Mayport Shrimp
Fresh shrimp caught from the nearby Mayport waters, often boiled or fried, showcasing local seafood quality.
- Vegetarian
- Vegan
- Gluten-free
Datil Pepper Hot Sauce
A spicy condiment native to the region, made from the locally grown Datil Pepper. Adds a kick to many local meals.
Maple Street Biscuit Company
A casual eatery known for its hearty breakfast and brunch offerings, including their famous biscuits and gravy.
BB's Restaurant + Bar
A trendy spot known for its eclectic menu and modern American dishes, featuring a lively atmosphere and a creative cocktail menu.
The Blue Fish Restaurant and Oyster Bar
Located in historic Avondale, this venue specializes in fresh seafood and a relaxed dining experience.
United States Dollar
Jacksonville offers moderate prices compared to other major U.S. cities, with a variety of options for dining and accommodation.
Average meal costs
- Budget
- $8-15 for fast food or local diners.
- Mid-range
- $20-35 per person at mid-range restaurants.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for a cappuccino.
Tipping culture
15-20% is standard for restaurants. Round up at cafes and for taxi drivers. Tipping is customary for most services.
FAQs: Bus from Des Moines, IA to Jacksonville, FL
Find answers to the most common questions about traveling from Des Moines, IA to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Des Moines, IA to Jacksonville, FL can start from as little as $158 (€128) when you book in advance. The average bus ticket price for Des Moines, IA to Jacksonville, FL is $184 (€148) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Jacksonville, FL is 31h 40m to travel the 1024 miles (1648 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Jacksonville, FL leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Jacksonville, FL leaves at 9:25 PM.
There are 1 buses a day from Des Moines, IA to Jacksonville, FL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Jacksonville, FL, you can count on Greyhound for the best way to get you to Jacksonville, FL. You can also check all possible bus companies who offer a service between Des Moines, IA and Jacksonville, FL and compare the amenities they offer before buying a bus ticket.
A trip to Jacksonville, FL from Des Moines, IA is worth doing but not as a day trip with a journey time of 31h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Jacksonville, FL is July.
Yes, you can take a bus between Des Moines, IA and Jacksonville, FL.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Jacksonville, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Jacksonville, FL for bus company Greyhound.
Whether you can cancel your bus ticket from Des Moines, IA to Jacksonville, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Jacksonville, FL.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Jacksonville, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Jacksonville, FL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Jacksonville, FL.
You can reserve your seat on the bus from Des Moines, IA to Jacksonville, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Jacksonville, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Jacksonville, FL with the following bus company: Greyhound.
Since neither Des Moines, IA nor Jacksonville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to Jacksonville, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jacksonville, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots. Common scams include overcharging by unlicensed taxi or ride-share drivers and fake ticket sellers near attractions. Staying aware of surroundings, using reputable transportation services, and avoiding isolated areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Des Moines, IA to Jacksonville, FL
Des Moines
Jacksonville
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St
information
Most popular bus connections from Des Moines, IA
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