Des Moines, IA to Jacksonville, FL bus

Wed, Nov 19
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Compare prices and tickets Des Moines, IA to Jacksonville, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Nov 19
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Journey information

Overview: Bus from Des Moines, IA to Jacksonville, FL

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Take a bus from Des Moines, IA to Jacksonville, FL and enjoy the approximately 1024 miles (1648 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 05:30, the last at 21:40.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1024 miles (1648 km)
Buses per day
1
First bus
05:30
Last bus
21:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Des Moines, IA to Jacksonville, FL

Find answers to the most common questions about traveling from Des Moines, IA to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Jacksonville, FL can start from as little as $269 (€218) when you book in advance. The average bus ticket price for Des Moines, IA to Jacksonville, FL is $310 (€251); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Jacksonville, FL is 37 h 15 min   to travel the 1022 mile (1648 km) long journey, with around there is 1 bus per day. Journey times can vary on weekends and holidays.
The first bus from Des Moines, IA to Jacksonville, FL leaves at 4: 35AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Des Moines, IA to Jacksonville, FL leaves at 9: 40PM.
The cheapest month to travel from Des Moines, IA to Jacksonville, FL by bus is October.
You have options as you can travel to Jacksonville, FL from Des Moines, IA 2 different ways: bus or flight.
No, the bus from Des Moines, IA to Jacksonville, FL has no accessibility options.
No, there are no bathrooms on board the bus from Des Moines, IA to Jacksonville, FL.
No, bikes are not allowed on board the bus from Des Moines, IA to Jacksonville, FL.

To find the cheapest bus tickets for your trip from Des Moines, IA to Jacksonville, FL, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Des Moines, IA to Jacksonville, FL.
    No, luggage for the bus from Des Moines, IA to Jacksonville, FL needs to be booked in addition.
    No, there are no additional luggage options for the bus from Des Moines, IA to Jacksonville, FL.
    Unfortunately, pets are not allowed on the bus from Des Moines, IA to Jacksonville, FL.
    No, there are no USB plugs on board the bus from Des Moines, IA to Jacksonville, FL.
    No, there is no WiFi on board the bus from Des Moines, IA to Jacksonville, FL.

    More options for your journey from Des Moines, IA to Jacksonville, FL

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