Des Moines, IA to Jacksonville, FL bus

Tue, Feb 17
+ Add return
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Rede Expressos
1,000+ travel companies
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Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to Jacksonville, FL

Showing times and prices for Feb 17

Cheapest price

$245

Average price

$245

Fastest journey

1 d 13 h 15 m

Average duration

1 d 13 h 15 m

Buses per day

1

Distance

1648 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Jacksonville, FL will cost around $245 if you buy it on the day, but the cheapest tickets can be found for only $245.

Fast buses

Of the 1 buses that leave Des Moines, IA for Jacksonville, FL on Tue, Feb 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Feb 17 the direct buses cover the 1648 km distance in an average of 1 d 13 h 15 m but if you time it right, some buses will get you there in just 1 d 13 h 15 m .

On Tue, Feb 17 the slowest buses will take 1 d 13 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
10:30AM37h15
Des Moines, IA
11:45PMJacksonville, FL
$2451One-way
0 transfers

Travel Information

Compare bus and flight for Des Moines, IA to Jacksonville, FL

Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from €231. For those with little time consider booking a flight which can get you there in 5h 55m. The ticket price range depends on the travel mode: a bus costs an average of €231, and a flight costs an average of €373.

Distance: 1024 miles (1648 km)

Compare bus with

Bus
Most popular
Flight

€231

Average price

Cheapest

€373

Average price

33h 55m

Average total duration

33h 25m

Onboard

+

30m

Additional time*

8h 55m

Average total duration

Fastest

5h 55m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Live departures

Des Moines, IA to Jacksonville, FL bus times

The table below shows live departures for Des Moines, IA to Jacksonville, FL buses for tomorrow, Tuesday, February 17. You can also manually refresh the results below to see updated bus journeys.

Last updated at 7:56 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound10:30 AM Des Moines, IA
37h15
11:45 PM Jacksonville, FL0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Jacksonville, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Feb 17
Wed
Feb 18
Thu
Feb 19
Fri
Feb 20
Sat
Feb 21
Sun
Feb 22
Mon
Feb 23

Journey information

Overview: Bus from Des Moines, IA to Jacksonville, FL

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to Jacksonville, FL run on average 1 times per day, taking around 33h 25m. Cheap bus tickets for this journey start at $291 (€231) if you book in advance.

The earliest bus runs at 05:30, the last at 21:40. The fastest bus covers the 1024 miles (1648 km) distance in 33h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1024 miles (1648 km)
Average bus duration
33h 25m
Cheapest ticket price
$291 (€231)
Buses per day
1
Fastest bus
33h 25m
First bus
05:30
Last bus
21:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Des Moines, IA to Jacksonville, FL

Find answers to the most common questions about traveling from Des Moines, IA to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Jacksonville, FL can start from as little as $291 (€231) when you book in advance. The average bus ticket price for Des Moines, IA to Jacksonville, FL is $291 (€231) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Jacksonville, FL is 33h 25m to travel the 1024 miles (1648 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Jacksonville, FL leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Jacksonville, FL leaves at 9:40 PM.
A trip to Jacksonville, FL from Des Moines, IA is worth doing but not as a day trip with a journey time of 33h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Jacksonville, FL is July.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Jacksonville, FL including taking a bus and flight.
No, there are no bathrooms on board the bus from Des Moines, IA to Jacksonville, FL.
No, the bus from Des Moines, IA to Jacksonville, FL has no accessibility options.
No, bikes are not allowed on board the bus from Des Moines, IA to Jacksonville, FL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to Jacksonville, FL.
No, luggage for the bus from Des Moines, IA to Jacksonville, FL needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to Jacksonville, FL.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Jacksonville, FL.
No, there are no USB plugs on board the bus from Des Moines, IA to Jacksonville, FL.
No, there is no WiFi on board the bus from Des Moines, IA to Jacksonville, FL.

More options for your journey from Des Moines, IA to Jacksonville, FL

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