- Must visit
The Walters Art Museum
Major free art museum with collections spanning ancient, medieval, Renaissance, and Asian art in Mount Vernon.
Cheapest price
$157
Average price
$157
Fastest journey
1 d 2 h 25 m
Average duration
1 d 2 h 25 m
Buses per day
1
Distance
1459 km
The best way to find a cheap bus ticket from Des Moines, IA to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Baltimore, MD will cost around $157 if you buy it on the day, but the cheapest tickets can be found for only $157.
It's difficult to get from Des Moines, IA to Baltimore, MD without transferring at least once.
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· Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Baltimore, MD among Omio's users. If you are prioritising price take the bus with prices starting from $229. For those with little time consider booking a flight which can get you there in 3h 30m. The ticket price range depends on the travel mode: a bus costs an average of $229, and a flight costs an average of $515.
Distance: 906 miles (1459 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$229 Average price Cheapest | $515 Average price | $206 Average price (fuel + tolls) |
26h 55m Average total duration 26h 25m Onboard + 30m Additional time* | 6h 30m Average total duration Fastest 3h 30m Onboard + 3h 0m Additional time* | 15h 20m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Baltimore, MD:
A bus is $286 (€232) less than a flight for this route with tickets for a flight from Des Moines, IA to Baltimore, MD costing on average $515 (€418).
Other travel options to Baltimore, MD take longer:
Bus takes on average 26h 25m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 09:20AM | Arrival Time 12:45PM | Duration 27h25 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $148 |
Operator Greyhound USA | Departure Time 09:45AM | Arrival Time 03:35AM | Duration 41h50 | Departure days Mon, Fri, Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 02:20PM | Arrival Time 04:45PM | Duration 26h25 | Departure days Thu | Cheapest price $229 |
The table below shows live departures for Des Moines, IA to Baltimore, MD buses for today, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 9:20 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 26h25 | 12:45 PM Baltimore, Haines St (Baltimore Downtown Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Baltimore, MD run on average 1 times per day, taking around 26h 25m. Cheap bus tickets for this journey start at $229 (€186) if you book in advance.
The earliest bus runs at 07:45, the last at 16:20. The fastest bus covers the 906 miles (1459 km) distance in 26h 25m.
Distance 906 miles (1459 km) |
Average bus duration 26h 25m |
Cheapest ticket price $229 (€186) |
Buses per day 1 |
Fastest bus 26h 25m |
First bus 7:45 AM |
Last bus 4:20 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Baltimore — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Baltimore trip today.
Major free art museum with collections spanning ancient, medieval, Renaissance, and Asian art in Mount Vernon.
Leading art museum known for its Cone Collection, contemporary works, and sculpture garden near Johns Hopkins.
Distinctive museum dedicated to self-taught artists, with imaginative exhibitions and a whimsical outdoor setting.
Baltimore's best-known waterfront district with promenades, harbor views, museums, and easy access to major attractions.
Historic waterfront neighborhood known for cobblestone streets, maritime character, and lively local atmosphere.
Popular hilltop park with one of the city's classic skyline and harbor viewpoints, especially photogenic at sunset.
Broiled or lightly fried cakes made with sweet blue crab meat and minimal filler. They are one of Baltimore’s signature foods and a classic Chesapeake Bay specialty.
Whole blue crabs steamed and coated with a bold spice blend, often eaten communally at crab houses. This is a defining Baltimore seafood tradition.
Baltimore barbecue specialty of charcoal-grilled roast beef sliced thin and served on a roll, often with raw onion and horseradish or tiger sauce.
Classic upscale steakhouse with old-school service, live music, and a refined atmosphere. A Baltimore institution for fine dining and cocktails.
Historic Lexington Market seafood counter famous for jumbo lump crab cakes. Casual, bustling, and one of the city’s most iconic food stops.
Popular local cafe known for elevated Chesapeake-inspired brunch dishes, crab specials, and friendly, lively service.
Moderate by U.S. standards. Hotels and dining vary by area; seafood and downtown spots cost more.
Tip 18-20% in restaurants; 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Des Moines, IA to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

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