- Must visit
The Baltimore Museum of Art
Renowned museum with major collections spanning contemporary, African, Asian, and American art, plus a celebrated sculpture garden.
Cheapest price
$135
Average price
$135
Fastest journey
1 d 2 h 25 m
Average duration
1 d 2 h 25 m
Buses per day
1
Distance
1459 km
The best way to find a cheap bus ticket from Des Moines, IA to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Baltimore, MD will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $135.
It's difficult to get from Des Moines, IA to Baltimore, MD without transferring at least once.
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· Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Baltimore, MD among Omio's users. If you are prioritising price take the bus with prices starting from $228. For those with little time consider booking a flight which can get you there in 3h 30m. The ticket price range depends on the travel mode: a bus costs an average of $228, and a flight costs an average of $513.
Distance: 906 miles (1459 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$228 Average price Cheapest | $513 Average price | $205 Average price (fuel + tolls) |
26h 55m Average total duration 26h 25m Onboard + 30m Additional time* | 6h 30m Average total duration Fastest 3h 30m Onboard + 3h 0m Additional time* | 15h 20m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Baltimore, MD:
A bus is $285 (€232) less than a flight for this route with tickets for a flight from Des Moines, IA to Baltimore, MD costing on average $513 (€418).
Other travel options to Baltimore, MD take longer:
Bus takes on average 26h 25m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:20AM | Arrival Time 12:45PM | Duration 26h25 | Departure days Everyday | Cheapest price $107 |
The table below shows live departures for Des Moines, IA to Baltimore, MD buses for tomorrow, Sunday, August 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 9:20 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 26h25 | 12:45 PM Baltimore, Haines St (Baltimore Downtown Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Baltimore, MD run on average 1 times per day, taking around 26h 25m. Cheap bus tickets for this journey start at $228 (€186) if you book in advance.
The earliest bus runs at 07:45, the last at 16:20. The fastest bus covers the 906 miles (1459 km) distance in 26h 25m.
Distance 906 miles (1459 km) |
Average bus duration 26h 25m |
Cheapest ticket price $228 (€186) |
Buses per day 1 |
Fastest bus 26h 25m |
First bus 7:45 AM |
Last bus 4:20 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Baltimore, MD — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Baltimore, MD trip today.
Renowned museum with major collections spanning contemporary, African, Asian, and American art, plus a celebrated sculpture garden.
Museum campus known for visionary and outsider art, mosaics, and immersive installations in a distinctive Baltimore setting.
Free art museum with ancient, medieval, Renaissance, and Asian works in a landmark Mount Vernon building.
Baltimore's signature waterfront district with promenades, museums, ships, and skyline views; ideal for first-time visitors.
Historic cobblestone waterfront neighborhood known for pubs, views, brick rowhouses, and a lively local atmosphere.
Elegant cultural district with monuments, museums, and 19th-century architecture surrounding tree-lined squares.
Maryland blue crab steamed with bold spice blend, then cracked by hand. It is Baltimore’s signature seafood ritual, especially around the harbor and summer crab feasts.
A rich cream-based soup with blue crab meat, often seasoned with sherry and Old Bay. It is a classic Baltimore comfort dish found in many local seafood houses.
A tomato-based vegetable soup with blue crab meat and Old Bay. It is a regional favorite in Baltimore, balancing sweet crab flavor with savory broth.
Refined waterfront seafood restaurant known for crab cakes, oysters, and Chesapeake dishes. Upscale but approachable, with strong local reputation in Fells Point.
Celebrated fine dining restaurant in a converted rowhouse, known for elegant Mid-Atlantic tasting menus and polished service in a historic Baltimore setting.
Casual local favorite for pit beef, turkey, and ham sandwiches. It is a go-to stop for the Baltimore area’s signature barbecue style.
Moderate for a major US city; hotels can be pricey, but dining and transit are usually manageable for tourists.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or $1 at cafes.
Find answers to the most common questions about traveling from Des Moines, IA to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

Most Des Moines, IA to Baltimore, MD buses use the to Baltimore, Haines St (Baltimore Downtown Bus Station) station pair. Use this guide to compare Des Moines, IA and Baltimore, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need