- Must visit
The Charles Hosmer Morse Museum of American Art
Outstanding museum in nearby Winter Park with the world's most comprehensive collection of works by Louis Comfort Tiffany.
Cheapest price
$156
Average price
$335
Fastest journey
1 d 10 h
Average duration
1 d 12 h 31 m
Buses per day
3
Distance
1826 km
The best way to find a cheap bus ticket from Des Moines, IA to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Orlando, FL will cost around $335 if you buy it on the day, but the cheapest tickets can be found for only $156.
Of the 3 buses that leave Des Moines, IA for Orlando, FL on Wed, Jun 17, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 17 the direct buses cover the 1826 km distance in an average of 1 d 12 h 31 m but if you time it right, some buses will get you there in just 1 d 10 h .
On Wed, Jun 17 the slowest buses will take 1 d 13 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $156. For those with little time consider booking a flight which can get you there in 2h 48m. The ticket price range depends on the travel mode: a bus costs an average of $156, and a flight costs an average of $170.
Distance: 1134 miles (1826 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$327 Average price Cheapest | $505 Average price | $278 Average price (fuel + tolls) |
33h 0m Average total duration 32h 30m Onboard + 30m Additional time* | 5h 48m Average total duration Fastest 2h 48m Onboard + 3h 0m Additional time* | 19h 51m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Orlando, FL:
A bus is $178 (€144) less than a flight for this route with tickets for a flight from Des Moines, IA to Orlando, FL costing on average $505 (€409).
Other travel options to Orlando, FL take longer:
Bus takes on average 32h 30m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:55AM | Arrival Time 09:20PM | Duration 35h25 | Departure days Fri | Cheapest price $297 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 03:59AM | Duration 41h29 | Departure days Tue | Cheapest price $388 |
Operator Greyhound | Departure Time 11:30AM | Arrival Time 01:25AM | Duration 37h55 | Departure days Wed | Cheapest price $427 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 12:25AM | Duration 34h05 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $163 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 12:25AM | Duration 34h00 | Departure days Wed | Cheapest price $156 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 09:50AM | Duration 43h05 | Departure days Thu | Cheapest price $296 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 04:59AM | Duration 37h39 | Departure days Sat, Sun | Cheapest price $263 |
Operator Greyhound | Departure Time 03:45PM | Arrival Time 10:50AM | Duration 43h05 | Departure days Fri | Cheapest price $425 |
The table below shows live departures for Des Moines, IA to Orlando, FL buses for today, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:30 AM Des Moines, IA | 41h29 | 3:59 AM Orlando, FL | 0 transfersDirect | |
![]() | 2:20 PM Des Moines, IA | 34h05 | 12:25 AM Orlando, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Orlando, FL run on average 3 times per day, taking around 32h 30m. Cheap bus tickets for this journey start at $156 (€126) if you book in advance.
The earliest bus runs at 04:45, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 34h 0m.
Distance 1134 miles (1826 km) |
Average bus duration 32h 30m |
Cheapest ticket price $156 (€126) |
Buses per day 3 |
Fastest bus 34h 0m |
First bus 4:45 AM |
Last bus 11:40 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Orlando — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando trip today.
Outstanding museum in nearby Winter Park with the world's most comprehensive collection of works by Louis Comfort Tiffany.
Major art museum in Loch Haven Park with American art, African art, and rotating exhibitions. A strong all-round cultural stop in Orlando.
History museum in a restored 1927 courthouse covering Central Florida's past through engaging permanent and temporary exhibits.
Signature downtown park with a walking loop, swan boats, skyline views, and frequent events. One of Orlando's easiest must-see areas.
Elegant shopping and strolling district lined with trees, boutiques, and public art. Popular for a more refined local side of Orlando.
Highly popular open-air entertainment district known for themed design, shops, and waterfront atmosphere. Very popular with visitors and influencers.
Florida’s signature dessert made with tart key lime filling in a crumb crust, often topped with whipped cream. It is a classic sweet treat across Orlando and Central Florida.
A seasonal Florida seafood specialty, usually served chilled with mustard sauce. It is prized for sweet, firm claw meat and is strongly associated with the state’s coastal food culture.
Fried alligator pieces, usually lightly breaded and served with dipping sauce. This is a distinctly Floridian dish that appears on many casual local menus.
A respected Orlando restaurant blending traditional Japanese technique with creative modern sushi and omakase-style options in a stylish setting.
A well-known gastropub in Winter Park serving refined Southern-inspired American dishes, craft beer, and seasonal Florida ingredients in a lively but polished setting.
A popular bakery and comfort food spot known for Southern breakfast, biscuits, pies, and nostalgic desserts. Casual, friendly, and highly regarded by locals.
Moderate overall. Theme parks and resort areas are pricey, but chain restaurants and casual dining offer better value.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxi/rideshare 10-15%, hotel staff USD 2-5, and round up for cafes if desired.
Find answers to the most common questions about traveling from Des Moines, IA to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

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