- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Des Moines, IA to Orlando, FL
Showing times, prices and bookable tickets for Nov 01
- Cheapest price on Nov 01
- S$ 326
- Average ticket price on Nov 01
- S$ 326
- Fastest journey on Nov 01
- 1 d 13 h 39 m
- Average journey duration on Nov 01
- 1 d 13 h 39 m
- Buses on Nov 01
- 1
- Distance
- 1826 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Orlando, FL will cost around S$ 326 if you buy it on the day, but the cheapest tickets can be found for only S$ 326.
Fast buses
On Sun, Nov 01, we found 1 buses from Des Moines, IA to Orlando, FL, including 1 direct services.
On Sun, Nov 01 the direct buses cover the 1826 km distance in an average of 1 d 13 h 39 m but if you time it right, some buses will get you there in just 1 d 13 h 39 m .
On Sun, Nov 01 the slowest buses will take 1 d 13 h 39 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:20 PM 37h39 Des Moines, IA 4:59 AM Orlando, FL S$ 326 1 One-way 0 transfers
3:20 PM 37h39 Des Moines, IA 4:59 AM Orlando, FL S$ 326 1 One-way 0 transfers
Journey information
Overview: Bus from Des Moines, IA to Orlando, FL
USAUSA
Buses from Des Moines, IA to Orlando, FL run on average 3 times per day, taking around 31h 46m. Cheap bus tickets for this journey start at S$ 167 if you book in advance.
The earliest bus runs at 04:45, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 28h 54m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1134 miles (1826 km) |
Average bus duration 31h 46m |
Cheapest ticket price S$ 167 |
Buses per day 3 |
Fastest bus 28h 54m |
First bus 4:45 AM |
Last bus 11:40 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Des Moines, IA to Orlando, FL trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Des Moines, IA to Orlando, FL.
Cheap bus tickets from Des Moines, IA to Orlando, FL can start from as little as S$ 167 when you book in advance. The average bus ticket price for Des Moines, IA to Orlando, FL is S$ 339 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Des Moines, IA to Orlando, FL leaves at 4:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Orlando, FL leaves at 11:40 PM.
There are 3 buses a day from Des Moines, IA to Orlando, FL which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Des Moines, IA to Orlando, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:50AM | Arrival Time 04:20PM | Duration 31h30 | Departure days Fri | Cheapest price S$ 241 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 11:59PM | Duration 37h39 | Departure days Fri | Cheapest price S$ 318 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 01:50AM | Duration 39h05 | Departure days Fri | Cheapest price S$ 288 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 03:59AM | Duration 41h29 | Departure days Tue | Cheapest price S$ 479 |
Operator Greyhound | Departure Time 11:30AM | Arrival Time 01:25AM | Duration 37h55 | Departure days Wed | Cheapest price S$ 528 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 12:25AM | Duration 34h05 | Departure days Tue, Wed, Thu, Sat | Cheapest price S$ 202 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 12:25AM | Duration 34h00 | Departure days Wed | Cheapest price S$ 193 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 09:50AM | Duration 43h05 | Departure days Thu | Cheapest price S$ 366 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 04:59AM | Duration 37h39 | Departure days Sat, Sun | Cheapest price S$ 326 |
Live departures
Des Moines, IA to Orlando, FL bus times
The table below shows live departures for Des Moines, IA to Orlando, FL buses for today, Saturday, October 31. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 2:20 PM Des Moines, IA | 37h39 | 3:59 AM Orlando, FL | 0 transfersDirect | |
| 3:20 PM Des Moines, IA | 37h39 | 4:59 AM Orlando, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Des Moines, IA to Orlando, FL buses with Omio?
FlixBus as well as Greyhound offer buses services from Des Moines, IA to Orlando, FL.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Orlando, FL.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Des Moines, IA to Orlando, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Orlando, FL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Des Moines, IA to Orlando, FL.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Orlando, FL.
Bus providers: FlixBus, Greyhound from Des Moines, IA to Orlando, FLYou can travel by bus between Des Moines, IA to Orlando, FL with FlixBus, Greyhound for as low as S$ 167. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
30h 0m
Cheapest FlixBus Price
S$ 167
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
28h 54m
Cheapest Greyhound Price
S$ 168
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Des Moines, IA and Orlando, FL
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Des Moines, IA to Orlando, FL, you can count on FlixBus, Greyhound for the best way to get you to Orlando, FL. You can also check all possible bus companies who offer a service between Des Moines, IA and Orlando, FL and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Orlando, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Orlando, FL for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Des Moines, IA to Orlando, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Orlando, FL.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Orlando, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Orlando, FL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Des Moines, IA to Orlando, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Des Moines, IA to Orlando, FL with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Orlando, FL with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Orlando, FL with the following bus company: FlixBus, Greyhound.
Complete guide to Orlando, FL
Things to do in Orlando, FL
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
- Recommended
Orange County Regional History Center
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
- Recommended
Rollins Museum of Art
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
- Must visit
Lake Eola Park
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
- Must visit
Park Avenue
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
- Recommended
Church Street District
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
Florida Catfish
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
- Gluten-free
Florida Shrimp
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
- Vegetarian
- Vegan
- Gluten-free
Cafecito
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Black Bean Deli
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Linda's La Cantina
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
The Ravenous Pig
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
US Dollar ($)
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Average meal costs
- Budget
- $10-15 for fast food or casual counter service.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Plan your visit to Orlando, FL
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Orlando, FL.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Orlando, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like theme parks and popular tourist spots. Common scams include overpriced taxi rides, timeshare presentations that pressure visitors, and fake ticket sellers near major attractions. It's important to use authorized transportation services and purchase tickets from official vendors to avoid fraud. Additionally, travelers should stay aware of their surroundings and avoid poorly lit or isolated areas at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Des Moines, IA to Orlando, FL
Find answers to the most common questions about traveling from Des Moines, IA to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Orlando, FL including taking a bus and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Des Moines, IA to Orlando, FL
Most Des Moines, IA to Orlando, FL buses use the Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Des Moines, IA and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Des Moines
Arrival bus stations in Orlando
Which Des Moines, IA station do buses to Orlando, FL leave from?
Buses from Des Moines, IA to Orlando, FL leave from Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). The station is 1 miles (3 km) from Des Moines, IA city centre at 1625 E Euclid Ave, Des Moines, IA 50313, USA.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.)1625 E Euclid Ave, Des Moines, IA 50313, USA
City-centre transport
Getting to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) from Des Moines city centre
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
TRUE
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) bus station facilities and services
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Tickets and information
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Parking, taxis and toilets
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Which Orlando, FL station do buses from Des Moines, IA arrive at?
Buses from Des Moines, IA to Orlando, FL most often arrive at Orlando, N John Young Pkwy (Greyhound Bus Station). Some services arrive at Orlando, The Florida Mall, so check your ticket before travel to confirm your Orlando, FL arrival station.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · S$ 4 · every ~6 min
125 · 41m · S$ 4 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · S$ 4 · every ~5 min
Bus stations for Des Moines, IA to Orlando, FL
Check bus stations information for Des Moines, IA and Orlando, FL, including where buses depart and arrive on this route.
When departing from Des Moines, IA , you have various bus station options to start your journey from including Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) . When arriving in Orlando, FL , you can end your journey in bus stations like Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall .Passengers board the bus most frequently from Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Orlando, N John Young Pkwy (Greyhound Bus Station), located 3 away from the city centre.
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Orlando, FL
Here are some other resources that might have the information you need
Most popular buses to and from Orlando, FL and Des Moines, IA
Most popular bus connections to Orlando, FL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
