- Must visit
Museum of Fine Arts, Boston
One of the largest art museums in the United States, known for its encyclopedic collection spanning ancient to contemporary works.
Cheapest price
$220
Average price
$220
Fastest journey
1 d 8 h 5 m
Average duration
1 d 8 h 5 m
Buses per day
1
Distance
1860 km
The best way to find a cheap bus ticket from Des Moines, IA to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Boston, MA will cost around $220 if you buy it on the day, but the cheapest tickets can be found for only $220.
It's difficult to get from Des Moines, IA to Boston, MA without transferring at least 2 times.
· ·
· · Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from $136. For those with little time consider booking a flight which can get you there in 4h 9m. The ticket price range depends on the travel mode: a bus costs an average of $136, and a flight costs an average of $77.
Distance: 1155 miles (1860 km)
| Bus | Most popular Flight |
|---|---|
$319 Average price Cheapest | $407 Average price |
36h 0m Average total duration 35h 30m Onboard + 30m Additional time* | 7h 9m Average total duration Fastest 4h 9m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Boston, MA:
A bus is $88 (€72) less than a flight for this route with tickets for a flight from Des Moines, IA to Boston, MA costing on average $407 (€334).
Other travel options to Boston, MA take longer:
Bus takes on average 35h 30m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:20AM | Arrival Time 06:25PM | Duration 32h05 | Departure days Tue, Sat | Cheapest price $152 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 01:50AM | Duration 35h30 | Departure days Mon, Thu, Fri | Cheapest price $218 |
The table below shows live departures for Des Moines, IA to Boston, MA buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 9:20 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 32h05 | 6:25 PM Boston, Bus Terminal South Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare flight and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Boston, MA run on average 1 times per day, taking around 35h 30m. Cheap bus tickets for this journey start at $136 (€111) but you can travel from only $77 (€63) by flight.
The earliest bus runs at 01:30, the last at 21:50. The fastest bus covers the 1155 miles (1860 km) distance in 35h 30m.
Distance 1155 miles (1860 km) |
Average bus duration 35h 30m |
Cheapest ticket price $136 (€111) |
Buses per day 1 |
Fastest bus 35h 30m |
First bus 1:30 AM |
Last bus 9:50 PM |
Cheapest Month Dec |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Discover the best of Boston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston trip today.
One of the largest art museums in the United States, known for its encyclopedic collection spanning ancient to contemporary works.
A distinctive Venetian-style museum with major European, Asian, and American art, famous for its intimate courtyard and historic 1990 art theft.
A family-friendly science museum with hands-on exhibits, a planetarium, and broad appeal for visitors interested in technology and natural science.
Boston’s signature walking route linking many of the city’s most important historic sites, ideal for first-time visitors.
The oldest public park in the United States, serving as a central green space and gateway to the Freedom Trail.
A picturesque landscaped garden known for its lagoon, bridges, and swan boats, especially photogenic in spring and summer.
A creamy soup of clams, potatoes, and onions that is one of Boston’s signature comfort foods and a classic of New England cooking.
Sweet lobster meat served in a buttered split-top roll, often dressed lightly with mayo or warm butter. It is a beloved Boston-area seafood staple.
Slow-cooked beans traditionally baked with molasses and salt pork, tied to the city’s old nickname, 'Beantown,' and its colonial food history.
Highly regarded restaurant in Cambridge near Boston, known for refined Eastern Mediterranean cooking, excellent ingredients, and a warm upscale atmosphere.
Iconic North End bakery best known for cannoli and other Italian pastries, popular with both locals and visitors seeking a classic Boston sweet stop.
Small, celebrated North End seafood spot known for lobster rolls, oysters, and a lively atmosphere. A longtime favorite for classic Boston seafood.
Boston is pricey by U.S. standards, especially for hotels and dining, though casual food and transit are manageable.
Tip 18-20% in restaurants, 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5.
Find answers to the most common questions about traveling from Des Moines, IA to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need