Travel Information
Compare bus and flight for Des Moines, IA to Boston, MA
Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from $122. For those with little time consider booking a flight which can get you there in 4h 9m. The ticket price range depends on the travel mode: a bus costs an average of $122, and a flight costs an average of $92.
Distance: 1155 miles (1860 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$253 Average price Cheapest | $298 Average price |
37h 33m Average total duration 37h 3m Onboard + 30m Additional time* | 7h 9m Average total duration Fastest 4h 9m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Des Moines, IA to Boston, MA bus times
The table below shows live departures for Des Moines, IA to Boston, MA buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:30 PM Des Moines, IA | 35h20 | 2:50 AM Boston, MA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Boston, MA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
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Mar 28
Journey information
Overview: Bus from Des Moines, IA to Boston, MA
Buses from Des Moines, IA to Boston, MA run on average 1 times per day, taking around 37h 3m. Cheap bus tickets for this journey start at $122 (€99) but you can travel from only $92 (€74) by flight.
The earliest bus runs at 01:30, the last at 23:00. The fastest bus covers the 1155 miles (1860 km) distance in 35h 20m.
Distance 1155 miles (1860 km) |
Average bus duration 37h 3m |
Cheapest ticket price $122 (€99) |
Buses per day 1 |
Fastest bus 35h 20m |
First bus 01:30 |
Last bus 23:00 |
Cheapest month Dec |
Cheapest day Wed |
High season Oct - Dec |
Low season Apr - Jun |
FAQs: Bus from Des Moines, IA to Boston, MA
Find answers to the most common questions about traveling from Des Moines, IA to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

- Best sights: Freedom Trail, a 2.5-mile-long path through downtown Boston that passes by 16 significant historical sites
- Fenway Park, the iconic baseball stadium and home of the Boston Red Sox
- Museum of Fine Arts, one of the largest art museums in the United States with an extensive collection of artworks
- Boston Common, the oldest public park in the United States offering green space and historical landmarks
- New England Aquarium, a popular attraction featuring a wide variety of marine life and interactive exhibits.
- Things to do: Explore the historic streets of Beacon Hill, known for its charming cobblestone streets and Federal-style rowhouses
- Take a scenic walk along the Charles River Esplanade, offering beautiful views of the Boston skyline
- Visit the Boston Public Library, a stunning architectural landmark with impressive collections and exhibits
- Enjoy a guided tour of the historic USS Constitution, the world's oldest commissioned naval vessel still afloat
- Discover the vibrant atmosphere of Quincy Market, with its diverse food stalls and unique shops.
popular bus stations
Popular bus stations from Des Moines, IA to Boston, MA
Most popular bus connections from Des Moines, IA
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