Travel Information
Compare bus and flight for Des Moines, IA to Philadelphia, PA
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from $154. For those with little time consider booking a flight which can get you there in 3h 20m. The ticket price range depends on the travel mode: a bus costs an average of $154, and a flight costs an average of $222.
Distance: 969 miles (1561 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$236 Average price Cheapest | $248 Average price |
26h 1m Average total duration 25h 31m Onboard + 30m Additional time* | 6h 20m Average total duration Fastest 3h 20m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Des Moines, IA to Philadelphia, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:20AM | Arrival Time 03:45PM | Duration 29h25 | Departure days Sat | Cheapest price $310 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 01:50AM | Duration 39h05 | Departure days Sat | Cheapest price $257 |
Live departures
Des Moines, IA to Philadelphia, PA bus times
The table below shows live departures for Des Moines, IA to Philadelphia, PA buses for today, Saturday, May 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined+ FlixBus | 9:20 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 29h25 | 3:45 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 2 transfers | |
undefined · undefined · undefined | 9:20 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 26h40 | 1:00 PM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 2 transfers | |
undefined · undefined · undefined | 9:45 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 39h05 | 1:50 AM Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Philadelphia, PA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 03
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May 09
Why should you book Des Moines, IA to Philadelphia, PA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Des Moines, IA to Philadelphia, PA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Philadelphia, PA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Des Moines, IA to Philadelphia, PA.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Philadelphia, PA.
Journey information
Overview: Bus from Des Moines, IA to Philadelphia, PA
Buses from Des Moines, IA to Philadelphia, PA run on average 3 times per day, taking around 25h 31m. Cheap bus tickets for this journey start at $154 (€124) if you book in advance.
The earliest bus runs at 03:10, the last at 22:30. The fastest bus covers the 969 miles (1561 km) distance in 26h 40m.
Distance 969 miles (1561 km) |
Average bus duration 25h 31m |
Cheapest ticket price $154 (€124) |
Buses per day 3 |
Fastest bus 26h 40m |
First bus 3:10 AM |
Last bus 10:30 PM |
Cheapest Month Jul |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Apr - Jun |
Bus providers: Greyhound, FlixBus from Des Moines, IA to Philadelphia, PAYou can travel by bus between Des Moines, IA to Philadelphia, PA with Greyhound, FlixBus for as low as $154 (€124). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Des Moines, IA to Philadelphia, PA
Find answers to the most common questions about traveling from Des Moines, IA to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
- Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
- Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
- Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
- Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
- Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
- Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
- Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
- Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
- Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Des Moines, IA to Philadelphia, PA
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Philadelphia, PA
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