Des Moines, IA to New Orleans, LA bus with Greyhound

Fri, Jun 19
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Greyhound
Jefferson Lines
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2,000+ travel companies
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Jefferson Lines
FlixBus
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BlaBlaCar Bus
2,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to New Orleans, LA

Showing times and prices for Jun 19

Cheapest price

$134

Average price

$134

Fastest journey

1 d 1 h 30 m

Average duration

1 d 12 h 33 m

Buses per day

2

Distance

1333 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to New Orleans, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to New Orleans, LA will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $134.

Fast buses

It's difficult to get from Des Moines, IA to New Orleans, LA without transferring at least once.

  • Greyhound ·
    4:20 PM25h30
    Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
    5:50 PMNew Orleans, LA
    $1341One-way
    1 transfer
  • Greyhound · +FlixBusFlixBus+Greyhound
    4:20 PM47h35
    Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
    3:55 PMKenner, Louis Armstrong New Orleans International Airport (Airline Dr)
    $1341One-way
    5 transfers

Travel Information

Compare bus and flight for Des Moines, IA to New Orleans, LA

Omio recommends booking the bus as it is the most popular option from Des Moines, IA to New Orleans, LA among Omio's users. If you are prioritising price take the bus with prices starting from $140. For those with little time consider booking a flight which can get you there in 6h 19m. The ticket price range depends on the travel mode: a bus costs an average of $140, and a flight costs an average of $148.

Distance: 828 miles (1333 km)

Compare bus with

Most popular
Bus
Flight
Driving

$221

Average price

Cheapest

$381

Average price

$201

Average price

(fuel + tolls)

25h 35m

Average total duration

25h 5m

Onboard

+

30m

Additional time*

9h 19m

Average total duration

Fastest

6h 19m

Onboard

+

3h 0m

Additional time*

14h 55m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Des Moines, IA to New Orleans, LA is a bus with an average price of $221 (€180).

This is compared to other travel options from Des Moines, IA to New Orleans, LA:

A bus is $160 (€131) less than a flight for this route with tickets for a flight from Des Moines, IA to New Orleans, LA costing on average $381 (€310).

The fastest way to travel from Des Moines, IA to New Orleans, LA is by flight with an average journey time of 6h 19m.

Other travel options to New Orleans, LA take longer:

Bus takes on average 25h 5m.

It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and New Orleans, LA including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to New Orleans, LA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Des Moines, IA to New Orleans, LA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
02:30PM
Arrival Time
10:50PM
Duration
32h20
Departure days
Sat
Cheapest price
$260
Operator
Greyhound
Departure Time
04:20PM
Arrival Time
05:50PM
Duration
25h30
Departure days
Mon, Tue, Wed, Thu, Fri, Sun
Cheapest price
$121

Live departures

Des Moines, IA to New Orleans, LA bus times

The table below shows live departures for Des Moines, IA to New Orleans, LA buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 4:20 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
25h30
5:50 PM New Orleans, LA1 transfer
Greyhound · +FlixBusFlixBus+Greyhound4:20 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
47h35
3:55 PM Kenner, Louis Armstrong New Orleans International Airport (Airline Dr)5 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to New Orleans, LA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25

Why should you book Des Moines, IA to New Orleans, LA buses with Omio?

Greyhound as well as Jefferson Lines offer buses services from Des Moines, IA to New Orleans, LA.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to New Orleans, LA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Jefferson Lines to find the best option for your trip from Des Moines, IA to New Orleans, LA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to New Orleans, LA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to New Orleans, LA.

Journey information

Overview: Bus from Des Moines, IA to New Orleans, LA

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to New Orleans, LA run on average 2 times per day, taking around 25h 5m. Cheap bus tickets for this journey start at $140 (€114) if you book in advance.

The earliest bus runs at 05:30, the last at 21:10. The fastest bus covers the 828 miles (1333 km) distance in 25h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
828 miles (1333 km)
Average bus duration
25h 5m
Cheapest ticket price
$140 (€114)
Buses per day
2
Fastest bus
25h 30m
First bus
5:30 AM
Last bus
9:10 PM
Cheapest Month
May
Cheapest Day
Tue
High Season
Jan - Mar
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, Jefferson Lines from Des Moines, IA to New Orleans, LAYou can travel by bus between Des Moines, IA to New Orleans, LA with Greyhound, Jefferson Lines for as low as $140 (€114). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 30m
Cheapest Price
$140 (€114)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Jefferson Lines

Luggage & cancellation policy
Average Duration
24h 40m
Cheapest Price
$310 (€253)
Jefferson Lines frequency
1 a day

Complete guide to New Orleans

Things to do in New Orleans

Discover the best of New Orleans — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect New Orleans trip today.

  • Must visit

The National WWII Museum

A major campus of immersive exhibits on World War II, widely regarded as one of the top museums in the United States.

  • Must visit

New Orleans Museum of Art

The city’s leading fine arts museum, known for its broad collection and its sculpture garden in City Park.

  • Recommended

Ogden Museum of Southern Art

A respected museum focused on Southern art, with strong permanent collections and rotating exhibitions.

United States Dollar

Moderate for U.S. city travel. Food and drinks range widely, while hotels rise sharply during festivals and weekends.

Average meal costs

Budget
USD 10-18 for po'boys, fast food, or casual spots.
Mid-range
USD 25-45 per person at a standard sit-down restaurant.
Fine dining
USD 75-150+ per person at upscale restaurants.
Coffee
USD 3-6 for drip coffee or a latte.

Tipping culture

Tip 18-20% at restaurants; 20%+ for great service. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Tip musicians only if invited or a tip jar is out.

FAQs: Bus from Des Moines, IA to New Orleans, LA

Find answers to the most common questions about traveling from Des Moines, IA to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to New Orleans, LA can start from as little as $140 (€114) when you book in advance. The average bus ticket price for Des Moines, IA to New Orleans, LA is $221 (€180) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to New Orleans, LA is 25h 30m to travel the 828 miles (1333 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to New Orleans, LA leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to New Orleans, LA leaves at 9:10 PM.
There are 2 buses a day from Des Moines, IA to New Orleans, LA which require at least one change with Greyhound, Jefferson Lines. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to New Orleans, LA, you can count on Greyhound, Jefferson Lines for the best way to get you to New Orleans, LA. You can also check all possible bus companies who offer a service between Des Moines, IA and New Orleans, LA and compare the amenities they offer before buying a bus ticket.
A trip to New Orleans, LA from Des Moines, IA is worth doing but not as a day trip with a journey time of 25h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to New Orleans, LA is May.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and New Orleans, LA including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to New Orleans, LA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to New Orleans, LA for bus company Greyhound.
Some of the most interesting sights to explore in New Orleans, LA are:
  • French Quarter, a historic district known for its vibrant nightlife, colorful buildings, and rich cultural heritage
  • Jackson Square, a historic park in the heart of the French Quarter surrounded by iconic landmarks and street performers
  • St. Louis Cathedral, a stunning example of French Gothic architecture and the oldest continuously active Roman Catholic cathedral in the United States
  • Garden District, a picturesque neighborhood famous for its well-preserved antebellum mansions and lush gardens
  • National WWII Museum, an extensive museum offering immersive exhibits and artifacts detailing the American experience in World War II.
The best things to do in New Orleans, LA include:
  • Preservation Hall, enjoy traditional New Orleans jazz performances in an intimate and historic setting
  • Audubon Park, relax in this beautiful urban park featuring walking paths, a zoo, and a golf course
  • Frenchmen Street, experience the vibrant music scene with live performances in numerous bars and clubs
  • Steamboat Natchez, take a scenic cruise along the Mississippi River on an authentic paddlewheel steamboat
  • City Park, explore this expansive park with botanical gardens, an art museum, and outdoor activities.
Whether you can cancel your bus ticket from Des Moines, IA to New Orleans, LA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to New Orleans, LA.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to New Orleans, LA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to New Orleans, LA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to New Orleans, LA.
You can reserve your seat on the bus from Des Moines, IA to New Orleans, LA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to New Orleans, LA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to New Orleans, LA with the following bus company: Greyhound.
Since neither Des Moines, IA nor New Orleans, LA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Des Moines, IA to New Orleans, LA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In New Orleans, LA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the French Quarter. Common scams include overpriced taxi rides and street vendors selling counterfeit goods. It's advisable to avoid walking alone late at night in less populated neighborhoods and to use authorized transportation services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Des Moines, IA to New Orleans, LA

Most Des Moines, IA to New Orleans, LA buses use the to Kenner, Louis Armstrong New Orleans International Airport (Airline Dr) station pair, with some services arriving at New Orleans, LA. Use this guide to compare Des Moines, IA and New Orleans, LA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Des Moines
Arrival bus stations in New Orleans
Kenner, Louis Armstrong New Orleans International Airport (Airline Dr)
City-centre transport

Getting to Kenner, Louis Armstrong New Orleans International Airport (Airline Dr) from New Orleans city centre

Bus202 · 25m · $2 · every ~2 min
202 · 29m · $2 · every ~2 min
New Orleans, LA

Most popular buses to and from New Orleans, LA and Des Moines, IA

HomeBusesBuses in USABus tickets to New Orleans, LADes Moines, IA to New Orleans, LA bus

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