The cheapest and fastest buses from Des Moines, IA to New Orleans, LA
Cheapest price
$297
Average price
$297
Fastest journey
1 d 8 h 20 m
Average duration
1 d 8 h 20 m
Buses per day
1
Distance
1333 km
The best way to find a cheap bus ticket from Des Moines, IA to New Orleans, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to New Orleans, LA will cost around $297 if you buy it on the day, but the cheapest tickets can be found for only $297.
Of the 1 buses that leave Des Moines, IA for New Orleans, LA on Fri, Mar 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Mar 20 the direct buses cover the 1333 km distance in an average of 1 d 8 h 20 m but if you time it right, some buses will get you there in just 1 d 8 h 20 m .
On Fri, Mar 20 the slowest buses will take 1 d 8 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Des Moines, IA to New Orleans, LA
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to New Orleans, LA among Omio's users. If you are prioritising price take the bus with prices starting from $261. For those with little time consider booking a flight which can get you there in 6h 50m. The ticket price range depends on the travel mode: a bus costs an average of $261, and a flight costs an average of $458.
Distance: 828 miles (1333 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$261 Average price Cheapest | $482 Average price |
56h 48m Average total duration 56h 18m Onboard + 30m Additional time* | 9h 50m Average total duration Fastest 6h 50m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Des Moines, IA to New Orleans, LA bus times
The table below shows live departures for Des Moines, IA to New Orleans, LA buses for today, Thursday, March 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:30 PM Des Moines, IA | 32h20 | 11:50 PM New Orleans, LA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to New Orleans, LA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Journey information
Overview: Bus from Des Moines, IA to New Orleans, LA
Buses from Des Moines, IA to New Orleans, LA run on average 2 times per day, taking around 56h 18m. Cheap bus tickets for this journey start at $261 (€213) if you book in advance.
The earliest bus runs at 05:30, the last at 21:10. The fastest bus covers the 828 miles (1333 km) distance in 54h 10m.
Distance 828 miles (1333 km) |
Average bus duration 56h 18m |
Cheapest ticket price $261 (€213) |
Buses per day 2 |
Fastest bus 54h 10m |
First bus 05:30 |
Last bus 21:10 |
Cheapest month May |
Cheapest day Tue |
High season Jan - Mar |
Low season Apr - Jun |
FAQs: Bus from Des Moines, IA to New Orleans, LA
Find answers to the most common questions about traveling from Des Moines, IA to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.

- French Quarter, a historic district known for its vibrant nightlife, colorful buildings, and rich cultural heritage
- Jackson Square, a historic park in the heart of the French Quarter surrounded by iconic landmarks and street performers
- St. Louis Cathedral, a stunning example of French Gothic architecture and the oldest continuously active Roman Catholic cathedral in the United States
- Garden District, a picturesque neighborhood famous for its well-preserved antebellum mansions and lush gardens
- National WWII Museum, an extensive museum offering immersive exhibits and artifacts detailing the American experience in World War II.
- Preservation Hall, enjoy traditional New Orleans jazz performances in an intimate and historic setting
- Audubon Park, relax in this beautiful urban park featuring walking paths, a zoo, and a golf course
- Frenchmen Street, experience the vibrant music scene with live performances in numerous bars and clubs
- Steamboat Natchez, take a scenic cruise along the Mississippi River on an authentic paddlewheel steamboat
- City Park, explore this expansive park with botanical gardens, an art museum, and outdoor activities.
popular bus stations
Popular bus stations from Des Moines, IA to New Orleans, LA
Most popular bus connections from Des Moines, IA
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