- Must visit
Detroit Institute of Arts
Major fine arts museum known for its encyclopedic collection and Diego Rivera’s Detroit Industry Murals.
Cheapest price
$102
Average price
$102
Fastest journey
14 h 10 m
Average duration
19 h 22 m
Buses per day
3
Distance
877 km
The best way to find a cheap bus ticket from Des Moines, IA to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Detroit, MI will cost around $102 if you buy it on the day, but the cheapest tickets can be found for only $102.
It's difficult to get from Des Moines, IA to Detroit, MI without transferring at least once.
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FlixBus
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FlixBus
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· · Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $77. For those with little time consider booking a flight which can get you there in 11h 29m. The ticket price range depends on the travel mode: a bus costs an average of $77, and a flight costs an average of $309.
Distance: 544 miles (877 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$126 Average price Cheapest | $499 Average price | $121 Average price (fuel + tolls) |
14h 13m Average total duration 13h 43m Onboard + 30m Additional time* | 14h 29m Average total duration Fastest 11h 29m Onboard + 3h 0m Additional time* | 9h 2m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Detroit, MI:
A bus is $373 (€304) less than a flight for this route with tickets for a flight from Des Moines, IA to Detroit, MI costing on average $499 (€407).
Other travel options to Detroit, MI take longer:
Bus takes on average 13h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:30AM | Arrival Time 11:00PM | Duration 16h30 | Departure days Everyday | Cheapest price $91 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 06:50AM | Duration 20h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $102 |
Operator Greyhound | Departure Time 04:20PM | Arrival Time 05:10PM | Duration 23h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $92 |
The table below shows live departures for Des Moines, IA to Detroit, MI buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 5:30 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 14h10 | 8:40 PM Detroit, Greyhound Terminal | 1 transfer | |
· | 9:45 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 20h05 | 6:50 AM Detroit, Greyhound Terminal | 1 transfer | |
· · | 4:20 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 23h50 | 5:10 PM Detroit, Greyhound Terminal | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Des Moines, IA to Detroit, MI run on average 2 times per day, taking around 13h 43m. Cheap bus tickets for this journey start at $77 (€63) if you book in advance.
The earliest bus runs at 05:00, the last at 23:55. The fastest bus covers the 544 miles (877 km) distance in 14h 10m.
Distance 544 miles (877 km) |
Average bus duration 13h 43m |
Cheapest ticket price $77 (€63) |
Buses per day 2 |
Fastest bus 14h 10m |
First bus 5:00 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 1 day |
Discover the best of Detroit — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit trip today.
Major fine arts museum known for its encyclopedic collection and Diego Rivera’s Detroit Industry Murals.
Large museum in the Detroit area showcasing transportation, industry, design, and iconic American artifacts.
Historic Hitsville U.S.A. museum preserving the story of Motown Records and its legendary artists.
Popular waterfront promenade with skyline views, public art, and easy walking between downtown and riverfront parks.
Island park with gardens, trails, water views, and several cultural attractions, popular with locals and visitors.
Historic market district famous for murals, weekend markets, and one of Detroit’s strongest local atmospheres.
A rectangular, deep-pan pizza with a thick yet airy crust, caramelized cheese edges, and sauce layered on top. It is one of Detroit’s most iconic local foods.
A hot dog in a bun topped with chili, mustard, and chopped onions. The Detroit coney is a classic local fast-food staple tied to the city’s Greek-American diner tradition.
A traditional Detroit float made with Vernors ginger ale and vanilla ice cream. Despite the name, it is a distinctly Detroit dessert drink.
A long-running Hamtramck favorite for hearty Polish dishes in a warm, traditional basement setting near Detroit.
A respected modern Detroit restaurant known for seasonal small plates, strong cocktails, and an upscale but relaxed atmosphere.
A polished downtown dining room in the Detroit Foundation Hotel, known for contemporary American cooking and stylish surroundings.
Moderate for U.S. city travel. Hotels vary widely, while casual dining, coffee, and local transport are usually manageable for most visitors.
Tip 18-20% in restaurants before tax. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 1-5. Not usually expected for counter service, but appreciated.
Find answers to the most common questions about traveling from Des Moines, IA to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most Des Moines, IA to Detroit, MI buses use the to Detroit, Greyhound Terminal station pair. Use this guide to compare Des Moines, IA and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need