- Must visit
Detroit Institute of Arts
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
The best way to find a cheap bus ticket from Des Moines, IA to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Detroit, MI will cost around €69 if you buy it on the day, but the cheapest tickets can be found for only €68.
It's difficult to get from Des Moines, IA to Detroit, MI without transferring at least once.
·
|
| ||||||||||||
+
FlixBus+
|
| ||||||||||||
·
|
| ||||||||||||
+
FlixBus+
|
| ||||||||||||
Buses from Des Moines, IA to Detroit, MI run on average 2 times per day, taking around 14h 37m. Cheap bus tickets for this journey start at €54 if you book in advance.
The earliest bus runs at 05:00, the last at 23:55. The fastest bus covers the 544 miles (877 km) distance in 12h 50m.
Distance 544 miles (877 km) |
Average bus duration 14h 37m |
Cheapest ticket price €54 |
Buses per day 2 |
Fastest bus 12h 50m |
First bus 5:00 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 1 day |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Des Moines, IA to Detroit, MI.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:30AM | Arrival Time 08:15PM | Duration 13h45 | Departure days Everyday | Cheapest price €67 |
Operator Greyhound | Departure Time 08:05AM | Arrival Time 06:50AM | Duration 21h45 | Departure days Tue | Cheapest price €69 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 06:50AM | Duration 20h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €66 |
The table below shows live departures for Des Moines, IA to Detroit, MI buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 9:45 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 20h05 | 6:50 AM Detroit, Greyhound Terminal | 1 transfer | |
| Tuesday, November 3 | |||||
· | 5:30 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 16h30 | 11:00 PM Detroit, Greyhound Terminal | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Detroit, MI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit, MI trip today.
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Immersive museum of African American history, culture, and achievement with strong regional and national storytelling.
Motown’s original Studio A preserves the sound and stories behind legendary recordings that shaped popular music worldwide.
Riverfront promenade with public art, plazas, and skyline views; one of the city’s best places for a scenic walk.
Large island park with gardens, trails, beaches, and major attractions, offering a nature escape minutes from downtown.
Revived public square at the city center, hosting events, seasonal programming, and easy access to downtown landmarks.
A square deep-dish pizza with a crisp, caramelized cheese edge and striped sauce. It is Detroit’s signature pie, born in blue steel auto pans.
A hot dog topped with chili, mustard, and diced onions on a steamed bun. It is a classic Detroit street food tied to Greek-American diners.
A layered sandwich of corned beef, swiss cheese, coleslaw, and Russian dressing on grilled rye. It is a beloved deli staple in metro Detroit.
Acclaimed fine-dining restaurant focused on seasonal tasting menus and polished service. One of Detroit’s top special-occasion destinations.
Beloved Eastern Market bakery known for paczki, cakes, and old-school sweets. Expect a busy, nostalgic counter-service experience.
Historic downtown institution famous for Detroit-style square pizza in a lively, casual setting with old-school local character.
Moderate for US city breaks: hotels and dining are mid-priced, transit is limited, and car or rideshare costs can raise daily spend.
Tip 18-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or about 10% in cafes if there is table service.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Detroit, MI.
Find answers to the most common questions about traveling from Des Moines, IA to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most Des Moines, IA to Detroit, MI buses use the Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) to Detroit, Greyhound Terminal station pair. Use this guide to compare Des Moines, IA and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Check bus stations information for Des Moines, IA and Detroit, MI, including where buses depart and arrive on this route.
Here are some other resources that might have the information you need