- Must visit
Milwaukee Art Museum
Leading lakefront museum with strong decorative arts, American art, and iconic architecture. It is Milwaukee's signature cultural attraction.

Cheapest price
$211
Average price
$211
Fastest journey
18h 50m
Average duration
18h 50m
Buses per day
1
Distance
378 km
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Milwaukee, WI among Omio's users. If you are prioritising price take the bus with prices starting from $70. For those with little time consider booking a flight which can get you there in 7h 12m. The ticket price range depends on the travel mode: a bus costs an average of $70, and a flight costs an average of $182.
Distance: 307 miles (495 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$110 Average price Cheapest | $349 Average price | $72 Average price (fuel + tolls) |
10h 17m Average total duration 9h 47m Onboard + 30m Additional time* | 10h 12m Average total duration Fastest 7h 12m Onboard + 3h 0m Additional time* | 5h 27m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Milwaukee, WI:
A bus is $239 (€196) less than a flight for this route with tickets for a flight from Des Moines, IA to Milwaukee, WI costing on average $349 (€286).
Other travel options to Milwaukee, WI take longer:
Bus takes on average 9h 47m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Des Moines, IA to Milwaukee, WI and enjoy the approximately 307 miles (495 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Distance 307 miles (495 km) |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Milwaukee — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milwaukee trip today.
Leading lakefront museum with strong decorative arts, American art, and iconic architecture. It is Milwaukee's signature cultural attraction.
Science and technology museum with hands-on exhibits, a dome theater, and major industrial displays. Great for families and curious adults alike.
Large natural and human history museum with dinosaur fossils, the Streets of Old Milwaukee, and cultural collections. A classic city institution.
Revived historic warehouse district with boutiques, galleries, riverwalk access, and handsome architecture. Ideal for strolling and urban photography.
Scenic pedestrian route along the Milwaukee River linking downtown districts. It offers public art, bridges, and some of the city's best easy walks.
Large lakefront park with gardens, blufftop views, and access to North Point Lighthouse. A favorite for relaxing walks and skyline panoramas.
A bratwurst, often grilled and served with sauerkraut and mustard. Milwaukee's strong German heritage makes it one of the city's signature foods.
Beer-battered whitefish or perch, usually served with rye bread, slaw, and potato pancakes. A beloved Friday tradition tied to the city's Catholic and tavern culture.
Fresh cheese curds, often battered and fried. They reflect Wisconsin's dairy identity and are a staple snack in Milwaukee bars and restaurants.
Classic custard stand famed for fresh frozen custard and the Flavor of the Day. Casual, nostalgic, and deeply rooted in Milwaukee tradition.
Upscale supper club and seafood spot celebrated for its Friday fish fry, cocktails, and polished old-school Milwaukee atmosphere.
Traditional tavern and restaurant known for hearty German fare, sausages, and one of the city's classic Friday fish fry experiences.
Moderate for U.S. city breaks: hotels are often cheaper than Chicago, dining is mid-priced, and local transit is limited so visitors may spend more on rideshares or parking.
Tip 18-20% in restaurants, more for excellent service. Round up or tip about 10% for taxis. Cafes often use tip jars or screens; $1-2 or 10-15% is common.
Find answers to the most common questions about traveling from Des Moines, IA to Milwaukee, WI by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milwaukee, WI, this guide helps you travel smarter and with confidence.

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