Des Moines, IA to Phoenix, AZ bus with Jefferson Lines

Tue, May 19
+ Add return
Jefferson Lines
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Jefferson Lines
FlixBus
Alsa
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to Phoenix, AZ

Showing times and prices for May 19

Cheapest price

$462

Average price

$474

Fastest journey

1 d 11 h 40 m

Average duration

1 d 12 h 18 m

Buses per day

2

Distance

1858 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Phoenix, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Phoenix, AZ will cost around $474 if you buy it on the day, but the cheapest tickets can be found for only $462.

Fast buses

It's difficult to get from Des Moines, IA to Phoenix, AZ without transferring at least 2 times.

  • Jefferson Lines
    6:30 PM35h40
    Des Moines, IA
    6:10 AMPhoenix, AZ
    $4621One-way
    2 transfers
  • Jefferson Lines
    11:45 PM36h55
    Des Moines, IA
    12:40 PMPhoenix, AZ
    $4871One-way
    2 transfers

Travel Information

Compare bus and flight for Des Moines, IA to Phoenix, AZ

Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Phoenix, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $247. For those with little time consider booking a flight which can get you there in 3h 14m. The ticket price range depends on the travel mode: a bus costs an average of $247, and a flight costs an average of $189.

Distance: 1154 miles (1858 km)

Compare bus with

Bus
Most popular
Flight
Driving

$343

Average price

Cheapest

$395

Average price

$285

Average price

(fuel + tolls)

46h 46m

Average total duration

46h 16m

Onboard

+

30m

Additional time*

6h 14m

Average total duration

Fastest

3h 14m

Onboard

+

3h 0m

Additional time*

21h 21m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Des Moines, IA to Phoenix, AZ is a bus with an average price of $343 (€277).

This is compared to other travel options from Des Moines, IA to Phoenix, AZ:

A bus is $52 (€42) less than a flight for this route with tickets for a flight from Des Moines, IA to Phoenix, AZ costing on average $395 (€319).

The fastest way to travel from Des Moines, IA to Phoenix, AZ is by flight with an average journey time of 3h 14m.

Other travel options to Phoenix, AZ take longer:

Bus takes on average 46h 16m.

It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Phoenix, AZ including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Des Moines, IA to Phoenix, AZ among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Des Moines, IA to Phoenix, AZ Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:15AM
Arrival Time
12:10AM
Duration
47h55
Departure days
Thu, Sat
Cheapest price
$247
Operator
Greyhound
Departure Time
12:35AM
Arrival Time
12:10AM
Duration
47h35
Departure days
Sat
Cheapest price
$336
Operator
Greyhound
Departure Time
01:15AM
Arrival Time
01:10AM
Duration
47h55
Departure days
Mon, Fri, Sat
Cheapest price
$252
Operator
Jefferson Lines
Departure Time
06:30PM
Arrival Time
06:10AM
Duration
35h40
Departure days
Mon, Tue
Cheapest price
$462
Operator
Greyhound
Departure Time
09:20PM
Arrival Time
01:10PM
Duration
39h50
Departure days
Wed, Sun
Cheapest price
$256
Operator
Jefferson Lines
Departure Time
11:45PM
Arrival Time
12:40PM
Duration
36h55
Departure days
Mon, Tue
Cheapest price
$487

Live departures

Des Moines, IA to Phoenix, AZ bus times

The table below shows live departures for Des Moines, IA to Phoenix, AZ buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Jefferson Lines6:30 PM Des Moines, IA
35h40
6:10 AM Phoenix, AZ2 transfers
Jefferson Lines11:45 PM Des Moines, IA
36h55
12:40 PM Phoenix, AZ2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Phoenix, AZ by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
May 19
Wed
May 20
Thu
May 21
Fri
May 22
Sat
May 23
Sun
May 24
Mon
May 25

Journey information

Overview: Bus from Des Moines, IA to Phoenix, AZ

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to Phoenix, AZ run on average 1 times per day, taking around 46h 16m. Cheap bus tickets for this journey start at $247 (€200) but you can travel from only $189 (€152) by flight.

The earliest bus runs at 05:30, the last at 23:05. The fastest bus covers the 1154 miles (1858 km) distance in 39h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $189 (€152)
Distance
1154 miles (1858 km)
Average bus duration
46h 16m
Cheapest ticket price
$247 (€200)
Buses per day
1
Fastest bus
39h 50m
First bus
5:30 AM
Last bus
11:05 PM
Cheapest Month
Jan
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $189 (€152)

Bus providers: Jefferson Lines from Des Moines, IA to Phoenix, AZYou can travel by bus between Des Moines, IA to Phoenix, AZ with Jefferson Lines for as low as $189 (€152). When you search for schedules and tickets, Omio will show you the best journey

Jefferson Lines

Luggage & cancellation policy
Average Duration
35h 40m
Cheapest Price
$462 (€373)
Jefferson Lines frequency
2 a day

FAQs: Bus from Des Moines, IA to Phoenix, AZ

Find answers to the most common questions about traveling from Des Moines, IA to Phoenix, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Phoenix, AZ, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Phoenix, AZ can start from as little as $247 (€200) when you book in advance. The average bus ticket price for Des Moines, IA to Phoenix, AZ is $343 (€277) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Phoenix, AZ is 39h 50m to travel the 1154 miles (1858 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Phoenix, AZ leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Phoenix, AZ leaves at 11:05 PM.
There are 1 buses a day from Des Moines, IA to Phoenix, AZ which require at least one change with Jefferson Lines. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Phoenix, AZ, you can count on Jefferson Lines for the best way to get you to Phoenix, AZ. You can also check all possible bus companies who offer a service between Des Moines, IA and Phoenix, AZ and compare the amenities they offer before buying a bus ticket.
A trip to Phoenix, AZ from Des Moines, IA is worth doing but not as a day trip with a journey time of 39h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Phoenix, AZ is January.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Phoenix, AZ including taking a bus and flight.
No, the bus from Des Moines, IA to Phoenix, AZ has no accessibility options.
No, there are no bathrooms on board the bus from Des Moines, IA to Phoenix, AZ.
Some of the most interesting sights to explore in Phoenix, AZ are:
  • Desert Botanical Garden, a 140-acre garden showcasing a vast collection of arid-land plants and desert landscapes
  • Heard Museum, a renowned museum dedicated to the advancement of American Indian art and culture
  • Phoenix Art Museum, the largest art museum in the southwestern United States featuring diverse collections and exhibitions
  • Camelback Mountain, a popular hiking destination offering panoramic views of the city and surrounding desert
  • Papago Park, a scenic park known for its distinctive geological formations and recreational opportunities.
The best things to do in Phoenix, AZ include:
  • Musical Instrument Museum, a unique museum showcasing instruments from around the world
  • South Mountain Park and Preserve, offering extensive trails and breathtaking views of the desert landscape
  • Roosevelt Row, a vibrant arts district known for its galleries, murals, and local eateries
  • Phoenix Zoo, a family-friendly attraction with a wide variety of animals and interactive exhibits
  • Taliesin West, the winter home and architectural school of Frank Lloyd Wright, offering tours of its stunning design.
No, bikes are not allowed on board the bus from Des Moines, IA to Phoenix, AZ.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to Phoenix, AZ.
No, luggage for the bus from Des Moines, IA to Phoenix, AZ needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to Phoenix, AZ.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Phoenix, AZ.
No, there are no USB plugs on board the bus from Des Moines, IA to Phoenix, AZ.
No, there is no WiFi on board the bus from Des Moines, IA to Phoenix, AZ.
Since neither Des Moines, IA nor Phoenix, AZ are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Des Moines, IA to Phoenix, AZ among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Phoenix, AZ, travelers should be cautious of vehicle break-ins, especially in parking lots and popular tourist areas. Common scams include overcharging by some taxi or ride-share drivers and street vendors selling counterfeit goods. It's important to stay aware in crowded places, avoid leaving valuables visible in cars, and use reputable transportation services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Des Moines, IA to Phoenix, AZ

Des Moines
Phoenix
Phoenix, Sky Train Station
information
Phoenix, Bus Station (E Buckeye Rd)
information

More options for your journey from Des Moines, IA to Phoenix, AZ

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