- Must visit
Heard Museum
Leading museum of Native American art and culture, especially strong on Southwest Indigenous history and contemporary works.
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The cheapest and fastest buses from Des Moines, IA to Phoenix, AZ
Showing times and prices for Jul 04
Cheapest price
$242
Average price
$273
Fastest journey
1 d 23 h 35 m
Average duration
1 d 23 h 48 m
Buses per day
3
Distance
1858 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Phoenix, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Phoenix, AZ will cost around $273 if you buy it on the day, but the cheapest tickets can be found for only $242.
Fast buses
Of the 3 buses that leave Des Moines, IA for Phoenix, AZ on Sat, Jul 04, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jul 04 the direct buses cover the 1858 km distance in an average of 1 d 23 h 48 m but if you time it right, some buses will get you there in just 1 d 23 h 35 m .
On Sat, Jul 04 the slowest buses will take 1 d 23 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:15 AM47h55Des Moines, IA12:10 AMPhoenix, AZ$2421One-way0 transfers- 1:15 AM47h55Des Moines, IA1:10 AMPhoenix, AZ$2471One-way0 transfers
- 12:35 AM47h35Des Moines, IA12:10 AMPhoenix, AZ$3291One-way0 transfers
- 12:35 AM47h35Des Moines, IA12:10 AMPhoenix, AZ$3291One-way0 transfers
- 1:15 AM47h55Des Moines, IA1:10 AMPhoenix, AZ$2471One-way0 transfers
- 12:15 AM47h55Des Moines, IA12:10 AMPhoenix, AZ$2421One-way0 transfers
Travel Information
Compare bus and flight for Des Moines, IA to Phoenix, AZ
Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Phoenix, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $242. For those with little time consider booking a flight which can get you there in 3h 14m. The ticket price range depends on the travel mode: a bus costs an average of $242, and a flight costs an average of $185.
Distance: 1154 miles (1858 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$336 Average price Cheapest | $387 Average price | $280 Average price (fuel + tolls) |
46h 46m Average total duration 46h 16m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 3h 14m Onboard + 3h 0m Additional time* | 21h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Des Moines, IA to Phoenix, AZ is a bus with an average price of $336 (€277).
This is compared to other travel options from Des Moines, IA to Phoenix, AZ:
A bus is $51 (€42) less than a flight for this route with tickets for a flight from Des Moines, IA to Phoenix, AZ costing on average $387 (€319).
The fastest way to travel from Des Moines, IA to Phoenix, AZ is by flight with an average journey time of 3h 14m.
Other travel options to Phoenix, AZ take longer:
Bus takes on average 46h 16m.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Phoenix, AZ including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Des Moines, IA to Phoenix, AZ among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Des Moines, IA to Phoenix, AZ Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 12:10AM | Duration 47h55 | Departure days Sat | Cheapest price $242 |
Operator Greyhound | Departure Time 12:35AM | Arrival Time 12:10AM | Duration 47h35 | Departure days Sat | Cheapest price $329 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 01:10AM | Duration 47h55 | Departure days Mon, Fri, Sat | Cheapest price $247 |
Operator Greyhound | Departure Time 04:20PM | Arrival Time 06:10AM | Duration 39h50 | Departure days Wed | Cheapest price $264 |
Operator Jefferson Lines | Departure Time 06:30PM | Arrival Time 06:10AM | Duration 35h40 | Departure days Mon, Tue | Cheapest price $452 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 05:10PM | Duration 47h35 | Departure days Wed | Cheapest price $198 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 01:10PM | Duration 39h50 | Departure days Sun | Cheapest price $301 |
Operator Jefferson Lines | Departure Time 11:45PM | Arrival Time 12:40PM | Duration 36h55 | Departure days Mon, Tue | Cheapest price $477 |
Live departures
Des Moines, IA to Phoenix, AZ bus times
The table below shows live departures for Des Moines, IA to Phoenix, AZ buses for tomorrow, Friday, July 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:15 AM Des Moines, IA | 47h55 | 12:10 AM Phoenix, AZ | 0 transfersDirect | |
| 12:35 AM Des Moines, IA | 47h35 | 12:10 AM Phoenix, AZ | 0 transfersDirect | |
| 1:15 AM Des Moines, IA | 47h55 | 1:10 AM Phoenix, AZ | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Phoenix, AZ by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Des Moines, IA to Phoenix, AZ
USAUSA
Buses from Des Moines, IA to Phoenix, AZ run on average 1 times per day, taking around 46h 16m. Cheap bus tickets for this journey start at $242 (€200) but you can travel from only $185 (€152) by flight.
The earliest bus runs at 05:30, the last at 23:05. The fastest bus covers the 1154 miles (1858 km) distance in 39h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $185 (€152)
Distance 1154 miles (1858 km) |
Average bus duration 46h 16m |
Cheapest ticket price $242 (€200) |
Buses per day 1 |
Fastest bus 39h 50m |
First bus 5:30 AM |
Last bus 11:05 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $185 (€152)
Bus providers: Jefferson Lines from Des Moines, IA to Phoenix, AZYou can travel by bus between Des Moines, IA to Phoenix, AZ with Jefferson Lines for as low as $185 (€152). When you search for schedules and tickets, Omio will show you the best journey
Jefferson Lines
Luggage & cancellation policy
Average Duration
35h 40m
Cheapest Price
$452 (€373)
Jefferson Lines frequency
2 a day
Complete guide to Phoenix
Things to do in Phoenix
Discover the best of Phoenix — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Phoenix trip today.
- Must visit
Phoenix Art Museum
The largest art museum in the Southwest, with strong American, Asian, Latin American, fashion, and modern collections.
- Must visit
Musical Instrument Museum
Major global museum displaying instruments from around the world, with immersive audio exhibits and special artist galleries.
- Must visit
Desert Botanical Garden
World-class desert garden in Papago Park, famous for cacti displays, seasonal light events, and Sonoran landscape photography.
- Must visit
Papago Park
Scenic desert park with red rock formations, easy trails, and postcard views; especially popular around Hole-in-the-Rock.
- Must visit
Camelback Mountain
Iconic hiking area and one of the most recognizable natural landmarks in Greater Phoenix, known for panoramic summit views.
Sonoran Hot Dog
A bacon-wrapped hot dog in a bolillo roll topped with beans, onion, tomato, mayonnaise, mustard, and jalapeño salsa. It reflects the strong Sonoran influence in Phoenix.
Chimichanga
A deep-fried burrito often filled with shredded beef or chicken and served with sauce, rice, and beans. Arizona widely claims it as a regional specialty.
- Vegetarian
Cheese Crisp
An Arizona classic of an open-faced crisp flour tortilla covered with melted cheese, sometimes topped with green chiles. It is a simple Southwestern staple.
The Fry Bread House
Beloved Indigenous restaurant specializing in fry bread, tacos, and stews, offering one of the city's most distinctive traditional food experiences.
Durant's
Classic Phoenix steakhouse with old-school charm, red leather booths, and a reputation for steaks, martinis, and historic atmosphere.
Pizzeria Bianco Phoenix
Celebrated wood-fired pizzeria known nationally for carefully made pies and quality ingredients in a relaxed but iconic setting.
United States Dollar
Phoenix is moderate by U.S. standards: casual dining is affordable, while hotels and upscale areas can cost more in peak season.
Average meal costs
- Budget
- USD 10-18 for fast food or a casual lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person before drinks and tip.
- Coffee
- USD 4-6 for a regular café coffee.
Tipping culture
Tip 18-20% at sit-down restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet.
FAQs: Bus from Des Moines, IA to Phoenix, AZ
Find answers to the most common questions about traveling from Des Moines, IA to Phoenix, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Phoenix, AZ, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Des Moines, IA to Phoenix, AZ can start from as little as $242 (€200) when you book in advance. The average bus ticket price for Des Moines, IA to Phoenix, AZ is $336 (€277) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Phoenix, AZ is 39h 50m to travel the 1154 miles (1858 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Phoenix, AZ leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Phoenix, AZ leaves at 11:05 PM.
There are 1 buses a day from Des Moines, IA to Phoenix, AZ which require at least one change with Jefferson Lines. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Phoenix, AZ, you can count on Jefferson Lines for the best way to get you to Phoenix, AZ. You can also check all possible bus companies who offer a service between Des Moines, IA and Phoenix, AZ and compare the amenities they offer before buying a bus ticket.
A trip to Phoenix, AZ from Des Moines, IA is worth doing but not as a day trip with a journey time of 39h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Phoenix, AZ is January.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Phoenix, AZ including taking a bus and flight.
No, the bus from Des Moines, IA to Phoenix, AZ has no accessibility options.
No, there are no bathrooms on board the bus from Des Moines, IA to Phoenix, AZ.
Some of the most interesting sights to explore in Phoenix, AZ are:
- Desert Botanical Garden, a 140-acre garden showcasing a vast collection of arid-land plants and desert landscapes
- Heard Museum, a renowned museum dedicated to the advancement of American Indian art and culture
- Phoenix Art Museum, the largest art museum in the southwestern United States featuring diverse collections and exhibitions
- Camelback Mountain, a popular hiking destination offering panoramic views of the city and surrounding desert
- Papago Park, a scenic park known for its distinctive geological formations and recreational opportunities.
The best things to do in Phoenix, AZ include:
- Musical Instrument Museum, a unique museum showcasing instruments from around the world
- South Mountain Park and Preserve, offering extensive trails and breathtaking views of the desert landscape
- Roosevelt Row, a vibrant arts district known for its galleries, murals, and local eateries
- Phoenix Zoo, a family-friendly attraction with a wide variety of animals and interactive exhibits
- Taliesin West, the winter home and architectural school of Frank Lloyd Wright, offering tours of its stunning design.
No, bikes are not allowed on board the bus from Des Moines, IA to Phoenix, AZ.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to Phoenix, AZ.
No, luggage for the bus from Des Moines, IA to Phoenix, AZ needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to Phoenix, AZ.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Phoenix, AZ.
No, there are no USB plugs on board the bus from Des Moines, IA to Phoenix, AZ.
No, there is no WiFi on board the bus from Des Moines, IA to Phoenix, AZ.
Since neither Des Moines, IA nor Phoenix, AZ are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Des Moines, IA to Phoenix, AZ among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Phoenix, AZ, travelers should be cautious of vehicle break-ins, especially in parking lots and popular tourist areas. Common scams include overcharging by some taxi or ride-share drivers and street vendors selling counterfeit goods. It's important to stay aware in crowded places, avoid leaving valuables visible in cars, and use reputable transportation services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Des Moines, IA to Phoenix, AZ
Most Des Moines, IA to Phoenix, AZ buses use the to Phoenix, Sky Train Station station pair, with some services arriving at Phoenix, Bus Station (E Buckeye Rd). Use this guide to compare Des Moines, IA and Phoenix, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Des Moines
Arrival bus stations in Phoenix
Phoenix, Sky Train Station
City-centre transport
Getting to Phoenix, Sky Train Station from Phoenix city centre
BusFlixBus 2054 · 10m · $1
1 · 15m · $2 · every ~4 min
TramA · 25m · $2 · every ~10 min
Phoenix, Bus Station (E Buckeye Rd)
City-centre transport
Getting to Phoenix, Bus Station (E Buckeye Rd) from Phoenix city centre
Bus13 · 11m · $2 · every ~4 min
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Phoenix, AZ
Here are some other resources that might have the information you need
Most popular buses to and from Phoenix, AZ and Des Moines, IA
Most popular bus connections to Phoenix, AZ
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