- Must visit
Phoenix Art Museum
A leading Southwestern art museum with major collections of American, Latin American, Asian, and Western works in Downtown Phoenix.
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The cheapest and fastest buses from Des Moines, IA to Phoenix, AZ
Showing times, prices and bookable tickets for Oct 01
Cheapest price on Oct 01
$154
Average ticket price on Oct 01
$165
Fastest journey on Oct 01
1 d 8 h 40 m
Average journey duration on Oct 01
1 d 20 h 15 m
Buses on Oct 01
4
Distance
1858 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Phoenix, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Phoenix, AZ will cost around $165 if you buy it on the day, but the cheapest tickets can be found for only $154.
Fast buses
It's difficult to get from Des Moines, IA to Phoenix, AZ without transferring at least 2 times.
+
FlixBus+6:00 AM32h40Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA12:40 PMPhoenix, Bus Station (E Buckeye Rd)$1541One-way2 transfers- · · +FlixBus7:35 PM54h24Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA11:59 PMPhoenix, Sky Train Station, AZ$1551One-way3 transfers
- +FlixBus+7:35 PM43h05Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA12:40 PMPhoenix, Bus Station (E Buckeye Rd)$1551One-way2 transfers
- +FlixBus+9:20 AM46h50Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA6:10 AMPhoenix, Bus Station (E Buckeye Rd)$1981One-way2 transfers
- +FlixBus+6:00 AM32h40Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA12:40 PMPhoenix, Bus Station (E Buckeye Rd)$1541One-way2 transfers
- +FlixBus+7:35 PM43h05Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA12:40 PMPhoenix, Bus Station (E Buckeye Rd)$1551One-way2 transfers
- +FlixBus+9:20 AM46h50Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA6:10 AMPhoenix, Bus Station (E Buckeye Rd)$1981One-way2 transfers
- · · +FlixBus7:35 PM54h24Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA11:59 PMPhoenix, Sky Train Station, AZ$1551One-way3 transfers
Des Moines, IA to Phoenix, AZ Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:00AM | Arrival Time 12:40PM | Duration 32h40 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $154 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 06:10AM | Duration 46h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $195 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 12:40PM | Duration 43h05 | Departure days Everyday | Cheapest price $155 |
Live departures
Des Moines, IA to Phoenix, AZ bus times
The table below shows live departures for Des Moines, IA to Phoenix, AZ buses for today, Wednesday, September 30. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · +FlixBus | 7:35 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 54h15 | 11:50 PM Phoenix, Sky Train Station, AZ | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Phoenix, AZ by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Des Moines, IA to Phoenix, AZ buses with Omio?
Greyhound operates all buses services from Des Moines, IA to Phoenix, AZ.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Phoenix, AZ.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Phoenix, AZ.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Phoenix, AZ.
Journey information
Overview: Bus from Des Moines, IA to Phoenix, AZ
USAUSA
Buses from Des Moines, IA to Phoenix, AZ run on average 2 times per day, taking around 40h 38m. Cheap bus tickets for this journey start at $214 but you can travel from only $184 by flight.
The earliest bus runs at 05:30, the last at 23:05. The fastest bus covers the 1154 miles (1858 km) distance in 36h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $184
Distance 1154 miles (1858 km) |
Average bus duration 40h 38m |
Cheapest ticket price $214 |
Buses per day 2 |
Fastest bus 36h 50m |
First bus 5:30 AM |
Last bus 11:05 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $184
Bus providers: Greyhound from Des Moines, IA to Phoenix, AZYou can travel by bus between Des Moines, IA to Phoenix, AZ with Greyhound for as low as $184. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
36h 50m
Cheapest Greyhound Price
$214
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Phoenix, AZ
Things to do in Phoenix, AZ
Discover the best of Phoenix, AZ — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Phoenix, AZ trip today.
- Must visit
Musical Instrument Museum
An immersive museum of musical instruments from around the world, with audio exhibits, concerts, and broad family appeal.
- Must visit
Heard Museum
A major Indigenous art museum presenting Native American and First Nations works, history, and contemporary voices.
- Must visit
Desert Botanical Garden
A vast desert garden with thousands of cactus species, seasonal blooms, and scenic trails that define the Sonoran landscape.
- Must visit
Camelback Mountain
Phoenix’s signature mountain preserve offers summit hikes, panoramic city views, and one of the region’s most iconic outdoor experiences.
- Recommended
South Mountain Park and Preserve
A giant urban park with hiking, biking, desert scenery, and lookouts, making it a favorite for both visitors and locals.
Sonoran Hot Dog
A Sonoran-style hot dog wrapped in bacon and topped with beans, onion, tomato, mayo, mustard, and jalapeño salsa. A Phoenix favorite with roots in nearby Sonora.
Chimichanga
Deep-fried burrito commonly filled with shredded beef or chicken, then topped with sauce and cheese. It is a classic Arizona-Mexican comfort dish.
- Vegetarian
- Gluten-free
Frijoles De La Olla
Stewed pinto beans, often cooked creamy and savory. A staple across Phoenix Mexican and Sonoran tables, usually served as a side with many local meals.
Kai Restaurant
Upscale restaurant by a Native American chef highlighting Indigenous Arizona ingredients like tepary beans, cholla buds, and mesquite in a modern setting.
El Caprichoso Hot Dogs
Beloved casual spot known for Sonoran hot dogs and other Tucson-style street food. Lively, no-frills, and one of Phoenix's iconic local bites.
Carolina's Mexican Food
Popular casual chain born in Phoenix, famous for green chile pork and simple Sonoran-style Mexican fare. Fast, reliable, and widely loved by locals.
United States dollar ($)
Moderate for U.S. city breaks: hotels vary by season, dining is mid-priced, and car costs often matter more than public transit.
Average meal costs
- Budget
- $10-18 for fast food or casual spots.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $3-6 for coffee drinks.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 per drink or coffee in cafes.
FAQs: Bus from Des Moines, IA to Phoenix, AZ
Find answers to the most common questions about traveling from Des Moines, IA to Phoenix, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Phoenix, AZ, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Des Moines, IA to Phoenix, AZ can start from as little as $214 when you book in advance. The average bus ticket price for Des Moines, IA to Phoenix, AZ is $302 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Phoenix, AZ is 36h 50m to travel the 1154 miles (1858 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Phoenix, AZ leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Phoenix, AZ leaves at 11:05 PM.
There are 2 buses a day from Des Moines, IA to Phoenix, AZ which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Phoenix, AZ, you can count on Greyhound for the best way to get you to Phoenix, AZ. You can also check all possible bus companies who offer a service between Des Moines, IA and Phoenix, AZ and compare the amenities they offer before buying a bus ticket.
When departing from Des Moines, IA , you have various bus station options to start your journey from including Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA . When arriving in Phoenix, AZ , you can end your journey in bus stations like Phoenix, Bus Station (E Buckeye Rd), Phoenix, Sky Train Station, AZ .Passengers board the bus most frequently from Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA, which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Phoenix, Bus Station (E Buckeye Rd), located 3 away from the city centre.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Phoenix, AZ including taking a bus and flight.
Yes, there are bathrooms on board the bus from Des Moines, IA to Phoenix, AZ for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Phoenix, AZ:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Des Moines, IA to Phoenix, AZ depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Phoenix, AZ.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Phoenix, AZ:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Phoenix, AZ:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Phoenix, AZ.
You can reserve your seat on the bus from Des Moines, IA to Phoenix, AZ with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Phoenix, AZ with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Phoenix, AZ with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Phoenix, AZ, travelers should be cautious of vehicle break-ins, especially in parking lots and popular tourist areas. Common scams include overcharging by some taxi or ride-share drivers and street vendors selling counterfeit goods. It's important to stay aware in crowded places, avoid leaving valuables visible in cars, and use reputable transportation services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Des Moines, IA to Phoenix, AZ
Most Des Moines, IA to Phoenix, AZ buses use the Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) to Phoenix, Bus Station (E Buckeye Rd) station pair, with some services arriving at Phoenix, Sky Train Station. Use this guide to compare Des Moines, IA and Phoenix, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Des Moines
Arrival bus stations in Phoenix
Which Des Moines, IA station do buses to Phoenix, AZ leave from?
Buses from Des Moines, IA to Phoenix, AZ leave from Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). The station is 1 miles (3 km) from Des Moines, IA city centre at 1625 E Euclid Ave, Des Moines, IA 50313, USA.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.)1625 E Euclid Ave, Des Moines, IA 50313, USA
City-centre transport
Getting to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) from Des Moines city centre
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
TRUE
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) bus station facilities and services
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Tickets and information
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Parking, taxis and toilets
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Which Phoenix, AZ station do buses from Des Moines, IA arrive at?
Buses from Des Moines, IA to Phoenix, AZ most often arrive at Phoenix, Bus Station (E Buckeye Rd). Some services arrive at Phoenix, Sky Train Station, so check your ticket before travel to confirm your Phoenix, AZ arrival station.
Phoenix, Bus Station (E Buckeye Rd)Phoenix Bus Station, 2115 E Buckeye Rd, Phoenix, AZ 85034, USA
City-centre transport
Getting to Phoenix, Bus Station (E Buckeye Rd) from Phoenix city centre
Phoenix, Bus Station (E Buckeye Rd) is 3 km from Phoenix city centre. Public transport options include:
Bus13 · 11m · $2 · every ~4 min
Phoenix, Bus Station (E Buckeye Rd) bus station facilities and services
Phoenix, Bus Station (E Buckeye Rd) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets inside.
Wi-Fi and ATMs
Free Wi-Fi throughout the station. ATMs are aTM located near the main entrance.
Tickets and information
Ticket office support is available at Phoenix, Bus Station (E Buckeye Rd).
Parking, taxis and toilets
Available at Phoenix, Bus Station (E Buckeye Rd): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Phoenix, Bus Station (E Buckeye Rd): Wheelchair accessible with assistance.
Phoenix, Sky Train StationPhoenix, AZ, USA
City-centre transport
Getting to Phoenix, Sky Train Station from Phoenix city centre
Phoenix, Sky Train Station is 7 km from Phoenix city centre. Public transport options include:
BusFlixBus 2054 · 10m · $1
1 · 15m · $2 · every ~4 min
TramA · 25m · $2 · every ~10 min
Phoenix, Sky Train Station bus station facilities and services
Phoenix, Sky Train Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi accessible at the station. ATMs are available at Phoenix, Sky Train Station.
Tickets and information
Ticket office support is available at Phoenix, Sky Train Station.
Parking, taxis and toilets
Available at Phoenix, Sky Train Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Phoenix, Sky Train Station: Wheelchair accessible with ramps.
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Phoenix, AZ
Here are some other resources that might have the information you need
Most popular buses to and from Phoenix, AZ and Des Moines, IA
Most popular bus connections to Phoenix, AZ
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