The cheapest and fastest buses from Des Moines, IA to Phoenix, AZ
Cheapest price
$462
Average price
$474
Fastest journey
1 d 11 h 40 m
Average duration
1 d 12 h 18 m
Buses per day
2
Distance
1858 km
The best way to find a cheap bus ticket from Des Moines, IA to Phoenix, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Phoenix, AZ will cost around $474 if you buy it on the day, but the cheapest tickets can be found for only $462.
It's difficult to get from Des Moines, IA to Phoenix, AZ without transferring at least 2 times.
6:30 PM35h40Des Moines, IA6:10 AMPhoenix, AZ$4621One-way2 transfers
11:45 PM36h55Des Moines, IA12:40 PMPhoenix, AZ$4871One-way2 transfers
6:30 PM35h40Des Moines, IA6:10 AMPhoenix, AZ$4621One-way2 transfers
11:45 PM36h55Des Moines, IA12:40 PMPhoenix, AZ$4871One-way2 transfers
Travel Information
Compare bus and flight for Des Moines, IA to Phoenix, AZ
Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Phoenix, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $247. For those with little time consider booking a flight which can get you there in 3h 14m. The ticket price range depends on the travel mode: a bus costs an average of $247, and a flight costs an average of $189.
Distance: 1154 miles (1858 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$343 Average price Cheapest | $395 Average price | $285 Average price (fuel + tolls) |
46h 46m Average total duration 46h 16m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 3h 14m Onboard + 3h 0m Additional time* | 21h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to Phoenix, AZ:
A bus is $52 (€42) less than a flight for this route with tickets for a flight from Des Moines, IA to Phoenix, AZ costing on average $395 (€319).
Other travel options to Phoenix, AZ take longer:
Bus takes on average 46h 16m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Des Moines, IA to Phoenix, AZ Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 12:10AM | Duration 47h55 | Departure days Thu, Sat | Cheapest price $247 |
Operator Greyhound | Departure Time 12:35AM | Arrival Time 12:10AM | Duration 47h35 | Departure days Sat | Cheapest price $336 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 01:10AM | Duration 47h55 | Departure days Mon, Fri, Sat | Cheapest price $252 |
Operator Jefferson Lines | Departure Time 06:30PM | Arrival Time 06:10AM | Duration 35h40 | Departure days Mon, Tue | Cheapest price $462 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 01:10PM | Duration 39h50 | Departure days Wed, Sun | Cheapest price $256 |
Operator Jefferson Lines | Departure Time 11:45PM | Arrival Time 12:40PM | Duration 36h55 | Departure days Mon, Tue | Cheapest price $487 |
Live departures
Des Moines, IA to Phoenix, AZ bus times
The table below shows live departures for Des Moines, IA to Phoenix, AZ buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:30 PM Des Moines, IA | 35h40 | 6:10 AM Phoenix, AZ | 2 transfers | |
![]() | 11:45 PM Des Moines, IA | 36h55 | 12:40 PM Phoenix, AZ | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Phoenix, AZ by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 19
May 20
May 21
May 22
May 23
May 24
May 25
Journey information
Overview: Bus from Des Moines, IA to Phoenix, AZ
Buses from Des Moines, IA to Phoenix, AZ run on average 1 times per day, taking around 46h 16m. Cheap bus tickets for this journey start at $247 (€200) but you can travel from only $189 (€152) by flight.
The earliest bus runs at 05:30, the last at 23:05. The fastest bus covers the 1154 miles (1858 km) distance in 39h 50m.
Distance 1154 miles (1858 km) |
Average bus duration 46h 16m |
Cheapest ticket price $247 (€200) |
Buses per day 1 |
Fastest bus 39h 50m |
First bus 5:30 AM |
Last bus 11:05 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Bus providers: Jefferson Lines from Des Moines, IA to Phoenix, AZYou can travel by bus between Des Moines, IA to Phoenix, AZ with Jefferson Lines for as low as $189 (€152). When you search for schedules and tickets, Omio will show you the best journey
Jefferson Lines
FAQs: Bus from Des Moines, IA to Phoenix, AZ
Find answers to the most common questions about traveling from Des Moines, IA to Phoenix, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Phoenix, AZ, this guide helps you travel smarter and with confidence.

- Desert Botanical Garden, a 140-acre garden showcasing a vast collection of arid-land plants and desert landscapes
- Heard Museum, a renowned museum dedicated to the advancement of American Indian art and culture
- Phoenix Art Museum, the largest art museum in the southwestern United States featuring diverse collections and exhibitions
- Camelback Mountain, a popular hiking destination offering panoramic views of the city and surrounding desert
- Papago Park, a scenic park known for its distinctive geological formations and recreational opportunities.
- Musical Instrument Museum, a unique museum showcasing instruments from around the world
- South Mountain Park and Preserve, offering extensive trails and breathtaking views of the desert landscape
- Roosevelt Row, a vibrant arts district known for its galleries, murals, and local eateries
- Phoenix Zoo, a family-friendly attraction with a wide variety of animals and interactive exhibits
- Taliesin West, the winter home and architectural school of Frank Lloyd Wright, offering tours of its stunning design.
popular bus stations
Popular bus stations from Des Moines, IA to Phoenix, AZ
Most popular bus connections from Des Moines, IA
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