- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Sep 06
$68
Average ticket price on Sep 06
$72
Fastest journey on Sep 06
9 h 10 m
Average journey duration on Sep 06
11 h 31 m
Buses on Sep 06
5
Distance
527 km
The best way to find a cheap bus ticket from Milwaukee, WI to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to St. Louis, MO will cost around $72 if you buy it on the day, but the cheapest tickets can be found for only $68.
It's difficult to get from Milwaukee, WI to St. Louis, MO without transferring at least once.
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· Omio recommends booking the train as it is the most popular option from Milwaukee, WI to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $80 For those with little time, consider booking a flight, which has an average total journey time of 5h 53m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $80, while a flight costs an average of $614.
Distance: 327 miles (527 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$80 Average price Cheapest | $129 Average price | $614 Average price |
9h 33m Average total duration 9h 3m Onboard + 30m Additional time* | 7h 7m Average total duration 6h 37m Onboard + 30m Additional time* | 5h 53m Average total duration Fastest 3h 53m Onboard + 2h 0m Additional time* |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milwaukee, WI to St. Louis, MO:
A bus is $49 (€40) less than a train for this route with tickets for a train from Milwaukee, WI to St. Louis, MO costing on average $129 (€104).
A bus is $534 (€432) less than a flight for this route with tickets for a flight from Milwaukee, WI to St. Louis, MO costing on average $614 (€496).
Other travel options to St. Louis, MO take longer:
Train takes on average 6h 37m.
Bus takes on average 9h 3m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:30AM | Arrival Time 03:40PM | Duration 9h10 | Departure days Everyday | Cheapest price $50 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 11:15PM | Duration 14h15 | Departure days Wed, Thu | Cheapest price $56 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 11:15PM | Duration 13h55 | Departure days Wed, Thu | Cheapest price $56 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 11:15PM | Duration 11h25 | Departure days Mon, Fri, Sat, Sun | Cheapest price $52 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 11:15PM | Duration 11h20 | Departure days Tue | Cheapest price $59 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 11:15PM | Duration 11h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $51 |
Operator Greyhound | Departure Time 12:15PM | Arrival Time 11:15PM | Duration 11h00 | Departure days Tue | Cheapest price $61 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 07:45AM | Duration 16h05 | Departure days Everyday | Cheapest price $66 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 06:20AM | Duration 9h50 | Departure days Wed, Thu, Sat, Sun | Cheapest price $48 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 07:45AM | Duration 11h15 | Departure days Mon, Tue | Cheapest price $82 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 06:25AM | Duration 9h50 | Departure days Fri | Cheapest price $52 |
The table below shows live departures for Milwaukee, WI to St. Louis, MO buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 6:30 AM Milwaukee, Intermodal Station | 9h10 | 3:40 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
FlixBus+ · | 11:50 AM Milwaukee, Intermodal Station | 11h25 | 11:15 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
FlixBus+ · | 12:10 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 11h05 | 11:15 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
FlixBus+ · | 3:40 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 16h05 | 7:45 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
+ FlixBus | 8:30 PM Milwaukee, Intermodal Station | 9h50 | 6:20 AM St. Louis, S 15th St (Civic center) | 1 transfer |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milwaukee, WI to St. Louis, MO run on average 5 times per day, taking around 9h 3m. Cheap bus tickets for this journey start at $47 (€38) if you book in advance.
The earliest bus runs at 01:55, the last at 23:30. The fastest bus covers the 327 miles (527 km) distance in 7h 40m.
Distance 327 miles (527 km) |
Average bus duration 9h 3m |
Cheapest ticket price $47 (€38) |
Buses per day 5 |
Fastest bus 7h 40m |
First bus 1:55 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Milwaukee, WI to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Milwaukee, WI to St. Louis, MO buses use the Milwaukee, Intermodal Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Milwaukee, WI and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milwaukee, Intermodal Station is 1 km from Milwaukee city centre. Public transport options include:
Milwaukee, Intermodal Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafe and vending machines available.
Wi-Fi available in waiting areas. ATMs are aTM machines available inside the station.
Ticket office support is available at Milwaukee, Intermodal Station.
Available at Milwaukee, Intermodal Station: Parking, Taxis, WC.
Accessibility facilities are available at Milwaukee, Intermodal Station: ADA compliant with elevators and ramps.
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) is 10 km from Milwaukee city centre. Public transport options include:
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food options are available within the airport terminal.
Wi-Fi is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). ATMs are aTMs are available in the airport terminal.
Ticket office support is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop).
Available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): The station is accessible with facilities for disabled passengers.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Here are some other resources that might have the information you need