- Must visit
The Neon Museum
Immersive museum preserving iconic Las Vegas signs in an outdoor boneyard. It is essential for understanding the city's visual history and neon design legacy.
Cheapest price
$143
Average price
$264
Fastest journey
1 d 10 h 40 m
Average duration
1 d 10 h 58 m
Buses per day
3
Distance
2213 km
The best way to find a cheap bus ticket from St. Louis, MO to Las Vegas, NV is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Las Vegas, NV will cost around $264 if you buy it on the day, but the cheapest tickets can be found for only $143.
Of the 3 buses that leave St. Louis, MO for Las Vegas, NV on Thu, Aug 06, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 2213 km distance in an average of 1 d 10 h 58 m but if you time it right, some buses will get you there in just 1 d 10 h 40 m .
On Thu, Aug 06 the slowest buses will take 1 d 11 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Las Vegas, NV among Omio's users. If you are prioritising price take the flight with prices starting from $107. For those with little time consider booking a flight which can get you there in 3h 35m. The ticket price range depends on the travel mode: a flight costs an average of $107, and a train costs an average of $259.
Distance: 1375 miles (2213 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$248 Average price | $173 Average price Cheapest | $302 Average price | $330 Average price (fuel + tolls) |
35h 22m Average total duration 34h 52m Onboard + 30m Additional time* | 6h 35m Average total duration Fastest 3h 35m Onboard + 3h 0m Additional time* | 39h 31m Average total duration 39h 1m Onboard + 30m Additional time* | 23h 17m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Las Vegas, NV:
A flight is $76 less than a bus for this route with tickets for a bus from St. Louis, MO to Las Vegas, NV costing on average $248.
A flight is $129 less than a train for this route with tickets for a train from St. Louis, MO to Las Vegas, NV costing on average $302.
Other travel options to Las Vegas, NV take longer:
Bus takes on average 34h 52m.
Train takes on average 39h 1m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:30AM | Arrival Time 11:40PM | Duration 65h10 | Departure days Wed | Cheapest price $418 |
Operator Greyhound | Departure Time 01:20PM | Arrival Time 01:50AM | Duration 36h30 | Departure days Tue | Cheapest price $139 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 12:50AM | Duration 35h10 | Departure days Thu, Sat, Sun | Cheapest price $143 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 12:50AM | Duration 34h40 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $122 |
Operator Greyhound | Departure Time 02:40PM | Arrival Time 01:50AM | Duration 35h10 | Departure days Fri | Cheapest price $329 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 11:20PM | Duration 56h10 | Departure days Sat | Cheapest price $323 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 08:35AM | Duration 35h05 | Departure days Tue | Cheapest price $156 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 09:35AM | Duration 35h05 | Departure days Thu, Fri | Cheapest price $294 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Las Vegas, NV run on average 11 times per day, taking around 34h 52m. Cheap bus tickets for this journey start at $122 but you can travel from only $107 by flight.
The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 1375 miles (2213 km) distance in 34h 40m.
Distance 1375 miles (2213 km) |
Average bus duration 34h 52m |
Cheapest ticket price $122 |
Buses per day 11 |
Fastest bus 34h 40m |
First bus 12:15 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 3 days |
Discover the best of Las Vegas, NV — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Las Vegas, NV trip today.
Immersive museum preserving iconic Las Vegas signs in an outdoor boneyard. It is essential for understanding the city's visual history and neon design legacy.
Housed in the former federal courthouse, this museum explores organized crime and law enforcement through interactive exhibits tied closely to Las Vegas history.
Museum with a huge private collection of Pinball machines and classic arcade games. Visitors can play many machines, making it a fun local favorite.
The city's most famous resort corridor, lined with landmark hotels, lights, and nonstop entertainment. It is the essential walking route for first-time visitors.
Historic downtown entertainment district known for neon canopies, street performers, and classic casinos. It offers a different atmosphere from the modern Strip.
Large conservatory and botanical display inside Bellagio with seasonal floral installations. It is a beloved free stop for elegant design and photos.
Shrimp cocktail became a Las Vegas classic through old casino specials. Chilled shrimp with zesty cocktail sauce remains an iconic Strip snack.
Prime rib was a longtime casino draw, served in generous cuts with jus and sides. It reflects the city's classic steakhouse and late-night dining culture.
A massive burger piled with bacon, cheese, onion rings, and sauces. It matches Las Vegas's taste for oversized, indulgent, showy comfort food.
Celebrated fine-dining restaurant by Joël Robuchon, offering refined French tasting menus in one of Las Vegas's most luxurious rooms.
Classic old-school steakhouse in Circus Circus, famed for prime rib, steaks, and a vintage Las Vegas atmosphere.
Historic Jewish deli known for towering sandwiches, matzo ball soup, and the signature pastrami Reuben in a lively casual setting.
Las Vegas is pricey for tourists, with high hotel rates, resort fees, dining, and rideshare costs. Budget options exist off-Strip, but central stays and nightlife raise daily spending fast.
Tip 15-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and round up or add $1 at cafes for good service.
Find answers to the most common questions about traveling from St. Louis, MO to Las Vegas, NV by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Las Vegas, NV, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Las Vegas, NV buses use the St. Louis, S 15th St (Civic center) to Las Vegas, S Las Vegas Blvd (Forever 21) station pair, with some services arriving at Las Vegas, 1st St (Downtown). Use this guide to compare St. Louis, MO and Las Vegas, NV bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Las Vegas, S Las Vegas Blvd (Forever 21) is 5 km from Las Vegas city centre. Public transport options include:
Las Vegas, S Las Vegas Blvd (Forever 21) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby restaurants on S Las Vegas Blvd.
Wi-Fi is available at Las Vegas, S Las Vegas Blvd (Forever 21). ATMs are available nearby on S Las Vegas Blvd.
Ticket office support is available at Las Vegas, S Las Vegas Blvd (Forever 21).
Available at Las Vegas, S Las Vegas Blvd (Forever 21): Parking, Taxis, WC.
Accessibility facilities are available at Las Vegas, S Las Vegas Blvd (Forever 21): Accessible for passengers with disabilities.
Las Vegas, 1st St (Downtown) is 1 km from Las Vegas city centre. Public transport options include:
Las Vegas, 1st St (Downtown) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food restaurants nearby
Free Wi-Fi in waiting area. ATMs are aTM located inside.
Ticket office support is available at Las Vegas, 1st St (Downtown).
Available at Las Vegas, 1st St (Downtown): Parking, Taxis, WC.
Accessibility facilities are available at Las Vegas, 1st St (Downtown): Wheelchair accessible.
Las Vegas, Gilespie Street (South Strip Transit Terminal) is 12 km from Las Vegas city centre. Public transport options include:
Las Vegas, Gilespie Street (South Strip Transit Terminal) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Vending machines and snack bars available.
Free Wi-Fi available throughout the terminal. ATMs are aTM machines located inside the terminal.
Ticket office support is available at Las Vegas, Gilespie Street (South Strip Transit Terminal).
Available at Las Vegas, Gilespie Street (South Strip Transit Terminal): Parking, Taxis, WC.
Accessibility facilities are available at Las Vegas, Gilespie Street (South Strip Transit Terminal): Fully accessible facilities for disabled passengers.
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