4.9
4.6The cheapest and fastest buses from St. Louis, MO to Chicago, IL
Cheapest price
$55
Average price
$89
Fastest journey
6 h 15 m
Average duration
7 h 55 m
Buses per day
4
Distance
419 km
The best way to find a cheap bus ticket from St. Louis, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Chicago, IL will cost around $89 if you buy it on the day, but the cheapest tickets can be found for only $55.
Of the 4 buses that leave St. Louis, MO for Chicago, IL on Tue, Nov 25, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Nov 25 the direct buses cover the 419 km distance in an average of 7 h 55 m but if you time it right, some buses will get you there in just 6 h 15 m .
On Tue, Nov 25 the slowest buses will take 12 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBusFlixBusFlixBus
undefined · undefinedFlixBusFlixBusFlixBusundefined · undefined
Travel Information
Compare train, bus, and flight for St. Louis, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a flight which can get you there in 1h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €28, and a flight costs an average of €253.
Distance: 260 miles (419 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€45 Average price Cheapest | €45 Average price | €316 Average price |
6h 50m Average total duration 6h 20m Onboard + 30m Additional time* | 5h 40m Average total duration 5h 10m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
St. Louis, MO to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 02:10PM | Duration 12h10 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 04:30PM | Duration 7h00 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 10:15PM | Duration 6h15 | Departure days Everyday | Cheapest price $63 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 05:45AM | Duration 6h15 | Departure days Everyday | Cheapest price $59 |
Live departures
St. Louis, MO to Chicago, IL bus times
The table below shows live departures for St. Louis, MO to Chicago, IL buses for today, Monday, November 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| undefined · undefined | 8:00 AM St. Louis, S 15th St (Civic center) | 12h10 | 8:10 PM Chicago, Union Station (Amtrak), IL | 1 transfer | |
| FlixBus | 3:30 PM St. Louis, S 15th St (Civic center) | 7h00 | 10:30 PM Chicago, Greyhound Bus Station | 0 transfersDirect | |
| FlixBus | 10:00 PM St. Louis, S 15th St (Civic center) | 6h15 | 4:15 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 27
Nov 28
Nov 29
Dec 01
Dec 03
Dec 04
Dec 05
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Dec 12
Journey information
Overview: Bus from St. Louis, MO to Chicago, IL
USAUSA
Buses from St. Louis, MO to Chicago, IL run on average 4 times per day, taking around 6h 20m. Cheap bus tickets for this journey start at $34 (€28) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 260 miles (419 km) distance in 6h 15m.
Distance 260 miles (419 km) |
Average bus duration 6h 20m |
Cheapest ticket price $34 (€28) |
Buses per day 4 |
Direct buses 2 |
Fastest bus 6h 15m |
First bus 00:15 |
Last bus 23:50 |
Bus providers: Greyhound, FlixBus from St. Louis, MO to Chicago, ILYou can travel by bus between St. Louis, MO to Chicago, IL with Greyhound, FlixBus for as low as $34 (€28). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from St. Louis, MO to Chicago, IL
Find answers to the most common questions about traveling from St. Louis, MO to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from St. Louis, MO to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from St. Louis, MO to Chicago, IL
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and St. Louis, MO
Most popular bus connections to Chicago, IL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
