St. Louis, MO to Chicago, IL bus with Greyhound

Fri, Jun 20
+ Add return
Greyhound
FlixBus
flibco
Rede Expressos
Alsa
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from St. Louis, MO to Chicago, IL

Showing times and prices for Jun 20

Cheapest price

$59

Average price

$112

Fastest journey

6 h 15 m

Average duration

9 h 16 m

Buses per day

4

Distance

419 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Chicago, IL will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $59.

Fast buses

Of the 4 buses that leave St. Louis, MO for Chicago, IL on Fri, Jun 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Jun 20 the direct buses cover the 419 km distance in an average of 9 h 16 m but if you time it right, some buses will get you there in just 6 h 15 m .

On Fri, Jun 20 the slowest buses will take 12 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBusFlixBus
09:45AM7h00
St. Louis, S 15th St (Civic center)
04:45PMChicago, Greyhound Bus Station
$591One-way
0 transfers
FlixBusFlixBus
04:00PM6h15
St. Louis, S 15th St (Civic center)
10:15PMChicago, Greyhound Bus Station
$631One-way
0 transfers
Greyhoundundefined · undefined
02:30AM12h05
St. Louis, S 15th St (Civic center)
02:35PMChicago, Greyhound Bus Station
$1641One-way
1 transfer
Greyhoundundefined · undefined
02:30AM11h45
St. Louis, S 15th St (Civic center)
02:15PMChicago, Union Station (Amtrak), IL
$1641One-way
1 transfer

Travel Information

Compare train, bus, and flight for St. Louis, MO to Chicago, IL

Omio recommends booking the train as it is the most popular option from St. Louis, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from €37. For those with little time consider booking a flight which can get you there in 1h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg.

Compare bus with

Bus
Most popular
Train
Flight

€57

Average price

€49

Average price

Cheapest

€318

Average price

7h 56m

Average duration

7h 26m

Onboard

+

30m

Additional time*

5h 30m

Average duration

5h 0m

Onboard

+

30m

Additional time*

4h 24m

Average duration

Fastest

1h 24m

Onboard

+

3h 0m

Additional time*

0.4 - 1.0kg

CO2 emissions

0.1 - 0.4kg

CO2 emissions

Lowest

1.3 - 2.5kg

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

St. Louis, MO to Chicago, IL bus times

Showing buses for today, Thursday, June 19
Last updated at 4:22 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus9:00 PM St. Louis, S 15th St (Civic center)
6h15
3:15 AM Chicago, Greyhound Bus Station0 transfersDirect
Friday, June 20
greyhoundundefined · undefined7:30 AM St. Louis, S 15th St (Civic center)
12h05
7:35 PM Chicago, Greyhound Bus Station1 transfer
greyhoundundefined · undefined7:30 AM St. Louis, S 15th St (Civic center)
11h45
7:15 PM Chicago, Union Station (Amtrak), IL1 transfer
meinfernbus_flixbusFlixBus2:45 PM St. Louis, S 15th St (Civic center)
7h00
9:45 PM Chicago, Greyhound Bus Station0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Chicago, IL by train, bus, or flight

Fri
Jun 20
Sat
Jun 21
Sun
Jun 22
Mon
Jun 23
Tue
Jun 24
Wed
Jun 25
Thu
Jun 26
Fri
Jun 27
Sat
Jun 28
Sun
Jun 29
Mon
Jun 30
Tue
Jul 01
Wed
Jul 02
Thu
Jul 03
Fri
Jul 04
Sat
Jul 05
Sun
Jul 06
Mon
Jul 07
Tue
Jul 08
Wed
Jul 09
Thu
Jul 10

Journey information

Overview: Bus from St. Louis, MO to Chicago, IL

USAUSA
USAUSA
Icon of bus
Buses from St. Louis, MO to Chicago, IL run on average 5 times per day, taking around 7h 26m. Cheap bus tickets for this journey start at $33 (€27) if you book in advance.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
259 miles (418 km)
Average bus duration
7h 26m
Cheapest ticket price
$33 (€27)
Buses per day
5
Direct buses
2
Fastest bus
6h 5m
First bus
08:30
Last bus
19:55
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound and FlixBus from St. Louis, MO to Chicago, IL

Find the best buses from St. Louis, MO to Chicago, IL with Omio's travel partners Greyhound and FlixBus from $35 (€29). We can find you the best deals, schedules and tickets when comparing and booking the best journey.

FlixBus is one of the most popular low-cost bus companies in Europe. Founded in Germany, FlixBus has expanded its services throughout Europe and even to the United States, giving travelers in both continents the option to take a long-distance bus at an affordable price. FlixBus also operates overnight buses on select routes throughout Europe. FlixBus offers only the Standard ticket for all its routes, which allows you to bring one carry-on bag and one checked bag per person. Additional fees apply for bringing extra luggage and making specific seat reservations, such as if you want to book an Extra Seat, Table Seat or the Panorama Seat. Standard amenities onboard include free Wi-Fi, power outlets to charge your phone, tablet or laptop during long bus journeys, extra legroom, luggage space and toilets.

Bus information from St. Louis, MO to Chicago, IL with FlixBus:

  • Average Duration: 6 h 39 min
  • Cheapest Price: $43

FAQs: Bus from St. Louis, MO to Chicago, IL

FAQs: Take the bus from St. Louis, MO to Chicago, IL with ease. Whether you want fast, cheap or something entirely different, our travel experts have the information you need to know so you can find the best option from St. Louis, MO to Chicago, IL.
FAQs

popular bus stations

Popular bus stations from St. Louis, MO to Chicago, IL

St. Louis
Chicago
The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to Chicago.
St. Louis, S 15th St (Civic center)
information
The major bus station for arrivals in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip to Chicago from St. Louis.
Chicago, Greyhound Bus Station
information
HomeBusesBuses in USABus tickets to Chicago, ILSt. Louis, MO to Chicago, IL bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone
More routes, destinations and providers
Currency
Language

Useful links