- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
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The cheapest and fastest buses from St. Louis, MO to Chicago, IL
Showing times, prices and bookable tickets for Oct 08
Cheapest price on Oct 08
zł368
Average ticket price on Oct 08
zł421
Fastest journey on Oct 08
6 h 5 m
Average journey duration on Oct 08
9 h 45 m
Buses on Oct 08
3
Distance
419 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Chicago, IL will cost around zł421 if you buy it on the day, but the cheapest tickets can be found for only zł368.
Fast buses
On Thu, Oct 08, we found 3 buses from St. Louis, MO to Chicago, IL, including 1 direct services.
On Thu, Oct 08 the direct buses cover the 419 km distance in an average of 9 h 45 m but if you time it right, some buses will get you there in just 6 h 5 m .
On Thu, Oct 08 the slowest buses will take 11 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
· 2:00 AM11h45St. Louis, S 15th St (Civic center)1:45 PMChicago, Union Station (Amtrak), ILzł3681One-way1 transfer
FlixBus11:30 PM6h05St. Louis, S 15th St (Civic center)5:35 AMChicago, Greyhound Bus Stationzł4211One-way0 transfers- · 8:45 AM11h25St. Louis, S 15th St (Civic center)8:10 PMChicago, Greyhound Bus Stationzł4741One-way1 transfer
- FlixBus11:30 PM6h05St. Louis, S 15th St (Civic center)5:35 AMChicago, Greyhound Bus Stationzł4211One-way0 transfers
- · 8:45 AM11h25St. Louis, S 15th St (Civic center)8:10 PMChicago, Greyhound Bus Stationzł4741One-way1 transfer
- · 2:00 AM11h45St. Louis, S 15th St (Civic center)1:45 PMChicago, Union Station (Amtrak), ILzł3681One-way1 transfer
Journey information
Overview: Bus from St. Louis, MO to Chicago, IL
USAUSA
Buses from St. Louis, MO to Chicago, IL run on average 4 times per day, taking around 7h 16m. Cheap bus tickets for this journey start at zł128 but you can travel from only zł111 by train.
There are 3 buses per day. The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 260 miles (419 km) distance in 4h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from zł111
Distance 260 miles (419 km) |
Average bus duration 7h 16m |
Cheapest ticket price zł128 |
Buses per day 4 |
Direct buses 3 |
Fastest bus 4h 25m |
First bus 12:15 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 35 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from zł111
St. Louis, MO to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 01:45PM | Duration 11h45 | Departure days Everyday | Cheapest price zł284 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 08:10PM | Duration 11h25 | Departure days Wed, Thu | Cheapest price zł321 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 04:05PM | Duration 6h05 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price zł154 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 08:35PM | Duration 6h05 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price zł149 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 05:35AM | Duration 6h05 | Departure days Mon, Thu, Sat | Cheapest price zł200 |
Live departures
St. Louis, MO to Chicago, IL bus times
The table below shows live departures for St. Louis, MO to Chicago, IL buses for tomorrow, Thursday, October 8. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 2:00 AM St. Louis, S 15th St (Civic center) | 11h45 | 1:45 PM Chicago, Union Station (Amtrak), IL | 1 transfer | |
| · | 8:45 AM St. Louis, S 15th St (Civic center) | 11h25 | 8:10 PM Chicago, Greyhound Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book St. Louis, MO to Chicago, IL buses with Omio?
FlixBus as well as Greyhound or Infobus offer buses services from St. Louis, MO to Chicago, IL.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Chicago, IL.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound or Infobus to find the best option for your trip from St. Louis, MO to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Chicago, IL.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound or Infobus to find the best option for your trip from St. Louis, MO to Chicago, IL.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Chicago, IL.
Bus providers: FlixBus, Greyhound, Infobus from St. Louis, MO to Chicago, ILYou can travel by bus between St. Louis, MO to Chicago, IL with FlixBus, Greyhound, Infobus for as low as zł111. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
6h 5m
Cheapest FlixBus Price
zł128
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Infobus Duration
4h 25m
Cheapest Infobus Price
zł612
Infobus frequency
1 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 20m
Cheapest Greyhound Price
zł145
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Chicago, IL
Things to do in Chicago, IL
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
- Must visit
Field Museum
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
- Must visit
Museum of Science and Industry
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
- Must visit
Millennium Park
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
- Must visit
Magnificent Mile
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
- Must visit
Chicago Riverwalk
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-Dish Pizza
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
Chicago-Style Hot Dog
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian Beef Sandwich
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Johnnie's Beef
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Superdawg Drive-In
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
Alinea
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
US dollar ($)
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
FAQs: Bus from St. Louis, MO to Chicago, IL
Find answers to the most common questions about traveling from St. Louis, MO to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Chicago, IL can start from as little as zł128 when you book in advance. The average bus ticket price for St. Louis, MO to Chicago, IL is zł275 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Chicago, IL is 4h 25m to travel the 260 miles (419 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Chicago, IL leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Chicago, IL leaves at 11:50 PM.
Yes, there are 3 direct buses a day from St. Louis, MO to Chicago, IL with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from St. Louis, MO to Chicago, IL, you can count on FlixBus, Greyhound, Infobus for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between St. Louis, MO and Chicago, IL and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, MO . When arriving in Chicago, IL , you can end your journey in bus stations like Chicago, Greyhound Bus Station, Chicago, Union Station (Amtrak), IL, Chicago, IL .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Chicago, Greyhound Bus Station, located 2 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Chicago, IL including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Chicago, IL:
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Chicago, IL for bus company FlixBus, Greyhound, Infobus.
Whether you can cancel your bus ticket from St. Louis, MO to Chicago, IL depends on the bus companies:
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Chicago, IL:
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Chicago, IL:
- Infobus
- 10€ per additional bag.
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Chicago, IL. The following conditions apply:
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Chicago, IL with the following bus company: FlixBus, Greyhound, Infobus
Yes, there are USB plugs on board the bus from St. Louis, MO to Chicago, IL with the following bus company: FlixBus, Greyhound, Infobus.
Yes, there is Wifi on board the bus from St. Louis, MO to Chicago, IL with the following bus company: FlixBus, Greyhound, Infobus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Chicago, IL
Most St. Louis, MO to Chicago, IL buses use the St. Louis, S 15th St (Civic center) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare St. Louis, MO and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Chicago
Which St. Louis, MO station do buses to Chicago, IL leave from?
Buses from St. Louis, MO to Chicago, IL leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · zł14 · every ~14 min
Bus19, 32, 40 · 8m · zł5 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. LouisSt. Louis, MO, USA
City-centre transport
Getting to St. Louis from St. Louis city centre
TRUE
St. Louis bus station facilities and services
St. Louis has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: There are food vendors in the station.
Wi-Fi and ATMs
Free wifi is available in the waiting area. ATMs are aTM available near the entrance.
Tickets and information
Ticket office support is available at St. Louis.
Parking, taxis and toilets
Available at St. Louis: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis: The station is accessible to wheelchairs.
Which Chicago, IL station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to Chicago, IL most often arrive at Chicago, Greyhound Bus Station. Some services arrive at Chicago, Union Station (Amtrak), so check your ticket before travel to confirm your Chicago, IL arrival station.
Chicago, Greyhound Bus Station630 W Harrison St, Chicago, IL 60607, USA
City-centre transport
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Bus7 · 8m · zł14 · every ~6 min
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak)Chicago Union Station, 225 S Canal St, Chicago, IL 60606, USA
City-centre transport
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Bus28, 151 · 7m · zł14 · every ~13 min
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
ChicagoChicago (Bus Station), Chicago, IL 60607, USA
City-centre transport
Getting to Chicago from Chicago city centre
Chicago is 3 km from Chicago city centre. Public transport options include:
Bus28, 151 · 7m · zł14 · every ~13 min
Chicago bus station facilities and services
Chicago has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi available in the waiting area. ATMs are aTM located near the main entrance.
Tickets and information
Ticket office support is available at Chicago.
Parking, taxis and toilets
Available at Chicago: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago: Wheelchair accessible with ramps and elevators.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and St. Louis, MO
Most popular bus connections to Chicago, IL
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