- Must visit
Philadelphia Museum of Art
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
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The cheapest and fastest buses from St. Louis, MO to Philadelphia, PA
Showing times and prices for Jul 22
Cheapest price
$118
Average price
$153
Fastest journey
22 h 15 m
Average duration
23 h 33 m
Buses per day
4
Distance
1301 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Philadelphia, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Philadelphia, PA will cost around $153 if you buy it on the day, but the cheapest tickets can be found for only $118.
Fast buses
Of the 4 buses that leave St. Louis, MO for Philadelphia, PA on Wed, Jul 22, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 22 the direct buses cover the 1301 km distance in an average of 23 h 33 m but if you time it right, some buses will get you there in just 22 h 15 m .
On Wed, Jul 22 the slowest buses will take 1 d 1 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2:00 AM23h20St. Louis, S 15th St (Civic center)2:20 AMPhiladelphia Bus Station$1181One-way0 transfers- 8:45 AM22h45St. Louis, S 15th St (Civic center)8:30 AMPhiladelphia Bus Station$1591One-way0 transfers
- 2:05 PM22h15St. Louis, S 15th St (Civic center)1:20 PMPhiladelphia Bus Station$1631One-way0 transfers
FlixBus+ · 11:30 PM25h50St. Louis, S 15th St (Civic center)2:20 AMPhiladelphia Bus Station$1701One-way2 transfers
- 2:05 PM22h15St. Louis, S 15th St (Civic center)1:20 PMPhiladelphia Bus Station$1631One-way0 transfers
- 8:45 AM22h45St. Louis, S 15th St (Civic center)8:30 AMPhiladelphia Bus Station$1591One-way0 transfers
- 2:00 AM23h20St. Louis, S 15th St (Civic center)2:20 AMPhiladelphia Bus Station$1181One-way0 transfers
- FlixBus+ · 11:30 PM25h50St. Louis, S 15th St (Civic center)2:20 AMPhiladelphia Bus Station$1701One-way2 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to Philadelphia, PA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from $96. For those with little time consider booking a flight which can get you there in 2h 9m. The ticket price range depends on the travel mode: a bus costs an average of $96, and a train costs an average of $151.
Distance: 808 miles (1301 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$127 Average price Cheapest | $418 Average price | $404 Average price | $259 Average price (fuel + tolls) |
22h 44m Average total duration 22h 14m Onboard + 30m Additional time* | 23h 30m Average total duration 23h 0m Onboard + 30m Additional time* | 5h 9m Average total duration Fastest 2h 9m Onboard + 3h 0m Additional time* | 13h 28m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Philadelphia, PA is a bus with an average price of $127 (€105).
This is compared to other travel options from St. Louis, MO to Philadelphia, PA:
A bus is $277 (€228) less than a flight for this route with tickets for a flight from St. Louis, MO to Philadelphia, PA costing on average $404 (€332).
A bus is $291 (€240) less than a train for this route with tickets for a train from St. Louis, MO to Philadelphia, PA costing on average $418 (€344).
The fastest way to travel from St. Louis, MO to Philadelphia, PA is by flight with an average journey time of 2h 9m.
Other travel options to Philadelphia, PA take longer:
Bus takes on average 22h 14m.
Train takes on average 23h 0m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Philadelphia, PA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Philadelphia, PA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $127 (€105) compared to roughly $259 (€213) in fuel and tolls — a saving of about $131 (€108). The journey takes 22h 14m versus 13h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
St. Louis, MO to Philadelphia, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 02:05AM | Duration 23h05 | Departure days Everyday | Cheapest price $105 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 08:10AM | Duration 22h25 | Departure days Everyday | Cheapest price $107 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 01:10PM | Duration 22h15 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $114 |
Operator Greyhound | Departure Time 02:05PM | Arrival Time 01:20PM | Duration 22h15 | Departure days Wed, Thu, Sat | Cheapest price $163 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 02:05AM | Duration 25h35 | Departure days Everyday | Cheapest price $111 |
Live departures
St. Louis, MO to Philadelphia, PA bus times
The table below shows live departures for St. Louis, MO to Philadelphia, PA buses for today, Tuesday, July 21. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:55 PM St. Louis, S 15th St (Civic center) | 22h15 | 1:10 PM Philadelphia Bus Station | 0 transfersDirect | |
| FlixBus+ · | 11:30 PM St. Louis, S 15th St (Civic center) | 25h50 | 2:20 AM Philadelphia Bus Station | 2 transfers | |
| Wednesday, July 22 | |||||
| 2:00 AM St. Louis, S 15th St (Civic center) | 23h20 | 2:20 AM Philadelphia Bus Station | 0 transfersDirect | |
| 8:45 AM St. Louis, S 15th St (Civic center) | 22h45 | 8:30 AM Philadelphia Bus Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Philadelphia, PA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Philadelphia, PA buses with Omio?
Greyhound operates all buses services from St. Louis, MO to Philadelphia, PA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Philadelphia, PA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Philadelphia, PA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Philadelphia, PA.
Journey information
Overview: Bus from St. Louis, MO to Philadelphia, PA
USAUSA
Buses from St. Louis, MO to Philadelphia, PA run on average 7 times per day, taking around 22h 14m. Cheap bus tickets for this journey start at $96 (€79) if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:40, the last at 23:55. The fastest bus covers the 808 miles (1301 km) distance in 22h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 808 miles (1301 km) |
Average bus duration 22h 14m |
Cheapest ticket price $96 (€79) |
Buses per day 7 |
Direct buses 3 |
Fastest bus 22h 5m |
First bus 1:40 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from St. Louis, MO to Philadelphia, PAYou can travel by bus between St. Louis, MO to Philadelphia, PA with Greyhound for as low as $96 (€79). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
22h 5m
Cheapest Price
$96 (€79)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Philadelphia, PA
Things to do in Philadelphia, PA
Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.
- Must visit
The Franklin Institute
Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.
- Must visit
Barnes Foundation
Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.
- Must visit
Independence National Historical Park
Historic district packed with foundational sites, cobblestone streets, and museums. The best base for first-time visitors.
- Must visit
Eakins Oval and Rocky Steps
Beloved park atop a hill with skyline views, trails, and the Rocky Steps approach. Great for walking and photography.
- Must visit
Rittenhouse Square
Walkable district of rowhouses, boutiques, and small parks. A classic local neighborhood for architecture and relaxed city strolling.
Philly Cheesesteak
A long roll packed with thin-sliced beef and melted cheese, often with fried onions. It is Philadelphia's signature street and comfort food.
- Vegetarian
- Vegan
Philadelphia Soft Pretzel
A soft pretzel with a distinct figure-eight twist and chewy texture. Sold by street vendors and bakeries, it is a classic Philadelphia snack.
Roast Pork Sandwich
A roast pork sandwich with garlicky pork, sharp provolone, and broccoli rabe. Many locals consider it the city's best traditional sandwich.
Vetri Cucina
Acclaimed fine dining restaurant by Chef Marc Vetri, known for refined Italian tasting menus and one of Philadelphia's top culinary experiences.
John's Roast Pork
Historic roast pork and cheesesteak shop in South Philadelphia, known for hearty sandwiches and a no-frills local atmosphere.
Rita's Italian Ice
Beloved local chain specializing in water ice and frozen custard. It is a go-to stop for a classic Philadelphia summer dessert.
US Dollar ($)
Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.
SEPTA
Get the appOfficial public transport app
Prices
- Single ticket
- $2.50
- Day pass
- $13.00
To the city center
Philadelphia Bus Terminal -> Philadelphia City Hall, Philadelphia, PA
- Distance
- 1 km
- Travel time
- 12 min
- SEPTA accepts contactless bank cards and mobile wallets on buses, trolleys, subways, and trains with Tap to Ride.
- Buy fares and plan trips in the official SEPTA app. Exact fare policies can vary by service, so check before boarding Regional Rail.
FAQs: Bus from St. Louis, MO to Philadelphia, PA
Find answers to the most common questions about traveling from St. Louis, MO to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Philadelphia, PA can start from as little as $96 (€79) when you book in advance. The average bus ticket price for St. Louis, MO to Philadelphia, PA is $127 (€105) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Philadelphia, PA is 22h 5m to travel the 808 miles (1301 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Philadelphia, PA leaves at 1:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Philadelphia, PA leaves at 11:55 PM.
Yes, there are 3 direct buses a day from St. Louis, MO to Philadelphia, PA with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from St. Louis, MO to Philadelphia, PA, you can count on Greyhound for the best way to get you to Philadelphia, PA. You can also check all possible bus companies who offer a service between St. Louis, MO and Philadelphia, PA and compare the amenities they offer before buying a bus ticket.
A trip to Philadelphia, PA from St. Louis, MO is worth doing but not as a day trip with a journey time of 22h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Philadelphia, PA is June.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Philadelphia, PA including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Philadelphia, PA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Philadelphia, PA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Philadelphia, PA are:
- Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
- Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
- Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
- Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
- Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
The best things to do in Philadelphia, PA include:
- Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
- Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
- Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
- Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
- Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from St. Louis, MO to Philadelphia, PA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Philadelphia, PA.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Philadelphia, PA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Philadelphia, PA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Philadelphia, PA.
You can reserve your seat on the bus from St. Louis, MO to Philadelphia, PA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Philadelphia, PA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Philadelphia, PA with the following bus company: Greyhound.
Since neither St. Louis, MO nor Philadelphia, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Philadelphia, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Philadelphia, PA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Center City and tourist hotspots. Scams involving overpriced taxi rides or unlicensed transportation are common, so using reputable services or ride-sharing apps is advised. Travelers should also be wary of street vendors selling counterfeit goods and avoid displaying valuables openly to reduce risk. Staying aware of surroundings and using well-lit, populated routes enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Philadelphia, PA
Most St. Louis, MO to Philadelphia, PA buses use the St. Louis, S 15th St (Civic center) to Philadelphia, Greyhound Bus Station station pair, with some services arriving at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). Use this guide to compare St. Louis, MO and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Philadelphia
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
Philadelphia, Greyhound Bus Station
City-centre transport
Getting to Philadelphia, Greyhound Bus Station from Philadelphia city centre
TrainAir, War, Wil, Med, Wtr, Lan, Pao, Nor, Che, Tre, Chw, Fox · 5m · $4 · every ~20 min
Bus17, 33, 44, 48, 62 · 2m · $4 · every ~34 min
SubwayL1 · 1m · $4 · every ~17 min
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park)
Philadelphia, Schuylkill Ave (Cira Centre South)
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Philadelphia, PA
Here are some other resources that might have the information you need
Most popular buses to and from Philadelphia, PA and St. Louis, MO
Most popular bus connections to Philadelphia, PA
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