St. Louis, MO to Philadelphia, PA bus with Greyhound

Sun, Sep 06
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2,000+ travel companies
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The cheapest and fastest buses from St. Louis, MO to Philadelphia, PA

Showing times, prices and bookable tickets for Sep 06

Cheapest price on Sep 06

CHF91

Average ticket price on Sep 06

CHF113

Fastest journey on Sep 06

22 h 15 m

Average journey duration on Sep 06

23 h 20 m

Buses on Sep 06

4

Distance

1301 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to Philadelphia, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Philadelphia, PA will cost around CHF113 if you buy it on the day, but the cheapest tickets can be found for only CHF91.

Fast buses

On Sun, Sep 06, we found 4 buses from St. Louis, MO to Philadelphia, PA, including 3 direct services.

On Sun, Sep 06 the direct buses cover the 1301 km distance in an average of 23 h 20 m but if you time it right, some buses will get you there in just 22 h 15 m .

On Sun, Sep 06 the slowest buses will take 1 d 1 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBusFlixBus+Greyhound ·
    11:30 PM25h35
    St. Louis, S 15th St (Civic center)
    2:05 AMPhiladelphia Bus Station
    CHF911One-way
    2 transfers
  • Greyhound
    8:45 AM22h25
    St. Louis, S 15th St (Civic center)
    8:10 AMPhiladelphia Bus Station
    CHF1131One-way
    0 transfers
  • Greyhound
    2:00 AM23h05
    St. Louis, S 15th St (Civic center)
    2:05 AMPhiladelphia Bus Station
    CHF1201One-way
    0 transfers
  • Greyhound
    1:55 PM22h15
    St. Louis, S 15th St (Civic center)
    1:10 PMPhiladelphia Bus Station
    CHF1271One-way
    0 transfers

Travel Information

Compare train, bus, and flight for St. Louis, MO to Philadelphia, PA

Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Philadelphia, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF90 For those with little time, consider booking a flight, which has an average total journey time of 4h 10m. Average ticket prices depend on the travel mode: a bus costs an average of CHF90, while a train costs an average of CHF342.

Distance: 808 miles (1301 km)

Compare bus with

Most popular
Bus
Train
Flight
Driving

CHF90

Average price

Cheapest

CHF342

Average price

CHF284

Average price

CHF215

Average price

(fuel + tolls)

22h 49m

Average total duration

22h 19m

Onboard

+

30m

Additional time*

23h 30m

Average total duration

23h 0m

Onboard

+

30m

Additional time*

4h 10m

Average total duration

Fastest

2h 10m

Onboard

+

2h 0m

Additional time*

13h 28m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Amtrak

Most popular train company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from St. Louis, MO to Philadelphia, PA is a bus with an average price of CHF90.

This is compared to other travel options from St. Louis, MO to Philadelphia, PA:

A bus is CHF195 less than a flight for this route with tickets for a flight from St. Louis, MO to Philadelphia, PA costing on average CHF284.

A bus is CHF252 less than a train for this route with tickets for a train from St. Louis, MO to Philadelphia, PA costing on average CHF342.

The fastest way to travel from St. Louis, MO to Philadelphia, PA is by flight with an average journey time of 2h 10m.

Other travel options to Philadelphia, PA take longer:

Bus takes on average 22h 19m.

Train takes on average 23h 0m.

It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Philadelphia, PA including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Philadelphia, PA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around CHF90 compared to roughly CHF215 in fuel and tolls — a saving of about CHF125. The journey takes 22h 19m versus 13h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by Greyhound.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

St. Louis, MO to Philadelphia, PA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
02:00AM
Arrival Time
02:20AM
Duration
23h20
Departure days
Everyday
Cheapest price
CHF65
Operator
Greyhound
Departure Time
08:45AM
Arrival Time
08:30AM
Duration
22h45
Departure days
Everyday
Cheapest price
CHF78
Operator
Greyhound
Departure Time
01:55PM
Arrival Time
01:10PM
Duration
22h15
Departure days
Sun
Cheapest price
CHF127
Operator
Greyhound
Departure Time
02:05PM
Arrival Time
01:20PM
Duration
22h15
Departure days
Mon, Tue, Wed, Thu, Fri, Sat
Cheapest price
CHF73
Operator
Greyhound
Departure Time
11:30PM
Arrival Time
02:20AM
Duration
25h50
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
CHF91

Live departures

St. Louis, MO to Philadelphia, PA bus times

The table below shows live departures for St. Louis, MO to Philadelphia, PA buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound2:00 AM St. Louis, S 15th St (Civic center)
23h20
2:20 AM Philadelphia Bus Station0 transfersDirect
Greyhound8:45 AM St. Louis, S 15th St (Civic center)
22h45
8:30 AM Philadelphia Bus Station0 transfersDirect
Greyhound2:05 PM St. Louis, S 15th St (Civic center)
22h15
1:20 PM Philadelphia Bus Station0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Philadelphia, PA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Sep 06
Mon
Sep 07
Tue
Sep 08
Wed
Sep 09
Thu
Sep 10
Fri
Sep 11
Sat
Sep 12

Why should you book St. Louis, MO to Philadelphia, PA buses with Omio?

Greyhound operates all buses services from St. Louis, MO to Philadelphia, PA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Philadelphia, PA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Philadelphia, PA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Philadelphia, PA.

Journey information

Overview: Bus from St. Louis, MO to Philadelphia, PA

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to Philadelphia, PA run on average 5 times per day, taking around 22h 19m. Cheap bus tickets for this journey start at CHF69 if you book in advance.

There are 3 buses per day. The earliest bus runs at 01:40, the last at 23:55. The fastest bus covers the 808 miles (1301 km) distance in 22h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
808 miles (1301 km)
Average bus duration
22h 19m
Cheapest ticket price
CHF69
Buses per day
5
Direct buses
3
Fastest bus
22h 5m
First bus
1:40 AM
Last bus
11:55 PM
Cheapest Month
Jun
Cheapest Day
Mon
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Sun
Least Busy Day
Sun
Best time to book
28 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from St. Louis, MO to Philadelphia, PAYou can travel by bus between St. Louis, MO to Philadelphia, PA with Greyhound for as low as CHF69. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
22h 5m
Cheapest Greyhound Price
CHF69
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Philadelphia, PA

Things to do in Philadelphia, PA

Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.

  • Must visit

Philadelphia Museum of Art

World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.

  • Must visit

The Franklin Institute

Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.

  • Must visit

Barnes Foundation

Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.

US Dollar ($)

Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$20-40 per person for a restaurant meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$3-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.

FAQs: Bus from St. Louis, MO to Philadelphia, PA

Find answers to the most common questions about traveling from St. Louis, MO to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to Philadelphia, PA can start from as little as CHF69 when you book in advance. The average bus ticket price for St. Louis, MO to Philadelphia, PA is CHF90 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Philadelphia, PA is 22h 5m to travel the 808 miles (1301 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Philadelphia, PA leaves at 1:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Philadelphia, PA leaves at 11:55 PM.
Yes, there are 3 direct buses a day from St. Louis, MO to Philadelphia, PA with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from St. Louis, MO to Philadelphia, PA, you can count on Greyhound for the best way to get you to Philadelphia, PA. You can also check all possible bus companies who offer a service between St. Louis, MO and Philadelphia, PA and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center) . When arriving in Philadelphia, PA , you can end your journey in bus stations like Philadelphia Bus Station, Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park), PA, Camden, Walter Rand Transportation Center, Malvern, Matthews Road (Park and Ride off Matthews Road), PA, Cherry Hill, NJ-38 (Cherry Hill Mall), Philadelphia, Schuylkill Ave (Cira Centre South), PA .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Philadelphia Bus Station, located 0 away from the city centre.
A trip to Philadelphia, PA from St. Louis, MO is worth doing but not as a day trip with a journey time of 22h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Philadelphia, PA is June.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Philadelphia, PA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Philadelphia, PA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Philadelphia, PA for bus company Greyhound.
Some of the most interesting sights to explore in Philadelphia, PA are:
  • Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
  • Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
  • Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
  • Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
  • Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
The best things to do in Philadelphia, PA include:
  • Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
  • Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
  • Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
  • Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
  • Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from St. Louis, MO to Philadelphia, PA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Philadelphia, PA.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Philadelphia, PA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Philadelphia, PA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Philadelphia, PA.
You can reserve your seat on the bus from St. Louis, MO to Philadelphia, PA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Philadelphia, PA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Philadelphia, PA with the following bus company: Greyhound.
Since neither St. Louis, MO nor Philadelphia, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Philadelphia, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Philadelphia, PA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Center City and tourist hotspots. Scams involving overpriced taxi rides or unlicensed transportation are common, so using reputable services or ride-sharing apps is advised. Travelers should also be wary of street vendors selling counterfeit goods and avoid displaying valuables openly to reduce risk. Staying aware of surroundings and using well-lit, populated routes enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from St. Louis, MO to Philadelphia, PA

Most St. Louis, MO to Philadelphia, PA buses use the St. Louis, S 15th St (Civic center) to Philadelphia, Greyhound Bus Station station pair, with some services arriving at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). Use this guide to compare St. Louis, MO and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in Philadelphia

Which St. Louis, MO station do buses to Philadelphia, PA leave from?

Buses from St. Louis, MO to Philadelphia, PA leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · CHF3 · every ~14 min
Bus19, 32, 40 · 8m · CHF1 · every ~9 min

St. Louis, S 15th St (Civic center) bus station facilities and services

St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).

Tickets and information

Ticket office support is available at St. Louis, S 15th St (Civic center).

Parking, taxis and toilets

Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.

More options for your journey from St. Louis, MO to Philadelphia, PA

Here are some other resources that might have the information you need

Most popular buses to and from Philadelphia, PA and St. Louis, MO

HomeBusesBuses in USABus tickets to Philadelphia, PASt. Louis, MO to Philadelphia, PA bus

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