- Must visit
Philadelphia Museum of Art
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Cheapest price on Sep 06
CHF91
Average ticket price on Sep 06
CHF113
Fastest journey on Sep 06
22 h 15 m
Average journey duration on Sep 06
23 h 20 m
Buses on Sep 06
4
Distance
1301 km
The best way to find a cheap bus ticket from St. Louis, MO to Philadelphia, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Philadelphia, PA will cost around CHF113 if you buy it on the day, but the cheapest tickets can be found for only CHF91.
On Sun, Sep 06, we found 4 buses from St. Louis, MO to Philadelphia, PA, including 3 direct services.
On Sun, Sep 06 the direct buses cover the 1301 km distance in an average of 23 h 20 m but if you time it right, some buses will get you there in just 22 h 15 m .
On Sun, Sep 06 the slowest buses will take 1 d 1 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus+
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FlixBus+
· Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Philadelphia, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF90 For those with little time, consider booking a flight, which has an average total journey time of 4h 10m. Average ticket prices depend on the travel mode: a bus costs an average of CHF90, while a train costs an average of CHF342.
Distance: 808 miles (1301 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
CHF90 Average price Cheapest | CHF342 Average price | CHF284 Average price | CHF215 Average price (fuel + tolls) |
22h 49m Average total duration 22h 19m Onboard + 30m Additional time* | 23h 30m Average total duration 23h 0m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 2h 10m Onboard + 2h 0m Additional time* | 13h 28m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Philadelphia, PA:
A bus is CHF195 less than a flight for this route with tickets for a flight from St. Louis, MO to Philadelphia, PA costing on average CHF284.
A bus is CHF252 less than a train for this route with tickets for a train from St. Louis, MO to Philadelphia, PA costing on average CHF342.
Other travel options to Philadelphia, PA take longer:
Bus takes on average 22h 19m.
Train takes on average 23h 0m.
Tickets start at around CHF90 compared to roughly CHF215 in fuel and tolls — a saving of about CHF125. The journey takes 22h 19m versus 13h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 02:20AM | Duration 23h20 | Departure days Everyday | Cheapest price CHF65 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 08:30AM | Duration 22h45 | Departure days Everyday | Cheapest price CHF78 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 01:10PM | Duration 22h15 | Departure days Sun | Cheapest price CHF127 |
Operator Greyhound | Departure Time 02:05PM | Arrival Time 01:20PM | Duration 22h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price CHF73 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 02:20AM | Duration 25h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price CHF91 |
The table below shows live departures for St. Louis, MO to Philadelphia, PA buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:00 AM St. Louis, S 15th St (Civic center) | 23h20 | 2:20 AM Philadelphia Bus Station | 0 transfersDirect | |
![]() | 8:45 AM St. Louis, S 15th St (Civic center) | 22h45 | 8:30 AM Philadelphia Bus Station | 0 transfersDirect | |
![]() | 2:05 PM St. Louis, S 15th St (Civic center) | 22h15 | 1:20 PM Philadelphia Bus Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Philadelphia, PA run on average 5 times per day, taking around 22h 19m. Cheap bus tickets for this journey start at CHF69 if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:40, the last at 23:55. The fastest bus covers the 808 miles (1301 km) distance in 22h 5m.
Distance 808 miles (1301 km) |
Average bus duration 22h 19m |
Cheapest ticket price CHF69 |
Buses per day 5 |
Direct buses 3 |
Fastest bus 22h 5m |
First bus 1:40 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Sun |
Best time to book 28 days |
Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.
Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.
Historic district packed with foundational sites, cobblestone streets, and museums. The best base for first-time visitors.
Beloved park atop a hill with skyline views, trails, and the Rocky Steps approach. Great for walking and photography.
Walkable district of rowhouses, boutiques, and small parks. A classic local neighborhood for architecture and relaxed city strolling.
A long roll packed with thin-sliced beef and melted cheese, often with fried onions. It is Philadelphia's signature street and comfort food.
A soft pretzel with a distinct figure-eight twist and chewy texture. Sold by street vendors and bakeries, it is a classic Philadelphia snack.
A roast pork sandwich with garlicky pork, sharp provolone, and broccoli rabe. Many locals consider it the city's best traditional sandwich.
Acclaimed fine dining restaurant by Chef Marc Vetri, known for refined Italian tasting menus and one of Philadelphia's top culinary experiences.
Historic roast pork and cheesesteak shop in South Philadelphia, known for hearty sandwiches and a no-frills local atmosphere.
Beloved local chain specializing in water ice and frozen custard. It is a go-to stop for a classic Philadelphia summer dessert.
Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.
Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.
Official public transport app
Philadelphia Bus Terminal -> Philadelphia City Hall, Philadelphia, PA
Find answers to the most common questions about traveling from St. Louis, MO to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Philadelphia, PA buses use the St. Louis, S 15th St (Civic center) to Philadelphia, Greyhound Bus Station station pair, with some services arriving at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). Use this guide to compare St. Louis, MO and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Philadelphia, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars and vending machines are available.
Free Wi-Fi available in the waiting area. ATMs are an ATM is available near the entrance.
Ticket office support is available at Philadelphia, Greyhound Bus Station.
Available at Philadelphia, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Greyhound Bus Station: The station is wheelchair accessible with ramps and elevators.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) is 2 km from Philadelphia city centre. Public transport options include:
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). ATMs are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Ticket office support is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): The bus stop is accessible with ramps.
Philadelphia, Schuylkill Ave (Cira Centre South) is 1 km from Philadelphia city centre. Public transport options include:
Philadelphia, Schuylkill Ave (Cira Centre South) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are available at Philadelphia, Schuylkill Ave (Cira Centre South).
Ticket office support is available at Philadelphia, Schuylkill Ave (Cira Centre South).
Available at Philadelphia, Schuylkill Ave (Cira Centre South): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Schuylkill Ave (Cira Centre South): Wheelchair accessible area.
Here are some other resources that might have the information you need