- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
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The cheapest and fastest buses from St. Louis, MO to San Francisco, CA
Showing times, prices and bookable tickets for Oct 29
Cheapest price on Oct 29
$168
Average ticket price on Oct 29
$187
Fastest journey on Oct 29
1 d 21 h 20 m
Average journey duration on Oct 29
2 d 18 m
Buses on Oct 29
5
Distance
2803 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Francisco, CA will cost around $187 if you buy it on the day, but the cheapest tickets can be found for only $168.
Fast buses
It's difficult to get from St. Louis, MO to San Francisco, CA without transferring at least 2 times.
· · 5:15 PM 45h20 St. Louis, S 15th St (Civic center) 12:35 PM San Francisco, Transit Center Bay 29 $168 1 One-way 2 transfers- · +
FlixBus8:40 AM 50h05 St. Louis, S 15th St (Civic center) 8:45 AM San Francisco, Townsend Street / 5th Street, CA $174 1 One-way 2 transfers - · +FlixBus
9:10 AM 49h35 St. Louis, Lambert International Airport 8:45 AM San Francisco, Townsend Street / 5th Street, CA $175 1 One-way 2 transfers - · ·
8:40 AM 48h30 St. Louis, S 15th St (Civic center) 7:10 AM San Francisco, Transit Center Bay 29 $208 1 One-way 2 transfers - · ·
9:10 AM 48h00 St. Louis, Lambert International Airport 7:10 AM San Francisco, Transit Center Bay 29 $209 1 One-way 2 transfers
- · ·
5:15 PM 45h20 St. Louis, S 15th St (Civic center) 12:35 PM San Francisco, Transit Center Bay 29 $168 1 One-way 2 transfers - · ·
9:10 AM 48h00 St. Louis, Lambert International Airport 7:10 AM San Francisco, Transit Center Bay 29 $209 1 One-way 2 transfers - · ·
8:40 AM 48h30 St. Louis, S 15th St (Civic center) 7:10 AM San Francisco, Transit Center Bay 29 $208 1 One-way 2 transfers - · +FlixBus
9:10 AM 49h35 St. Louis, Lambert International Airport 8:45 AM San Francisco, Townsend Street / 5th Street, CA $175 1 One-way 2 transfers - · +FlixBus
8:40 AM 50h05 St. Louis, S 15th St (Civic center) 8:45 AM San Francisco, Townsend Street / 5th Street, CA $174 1 One-way 2 transfers
Journey information
Overview: Bus from St. Louis, MO to San Francisco, CA
USAUSA
Buses from St. Louis, MO to San Francisco, CA run on average 5 times per day, taking around 45h 24m. Cheap bus tickets for this journey start at $132 (€111) if you book in advance.
The earliest bus runs at 01:20, the last at 23:25. The fastest bus covers the 1741 miles (2803 km) distance in 44h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1741 miles (2803 km) |
Average bus duration 45h 24m |
Cheapest ticket price $132 (€111) |
Buses per day 5 |
Fastest bus 44h 10m |
First bus 1:20 AM |
Last bus 11:25 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your St. Louis, MO to San Francisco, CA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from St. Louis, MO to San Francisco, CA.
Cheap bus tickets from St. Louis, MO to San Francisco, CA can start from as little as $132 (€111) when you book in advance. The average bus ticket price for St. Louis, MO to San Francisco, CA is $203 (€172) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from St. Louis, MO to San Francisco, CA leaves at 1:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to San Francisco, CA leaves at 11:25 PM.
There are 5 buses a day from St. Louis, MO to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
St. Louis, MO to San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:40AM | Arrival Time 08:45AM | Duration 50h05 | Departure days Everyday | Cheapest price $162 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 07:10AM | Duration 48h00 | Departure days Everyday | Cheapest price $158 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 12:35PM | Duration 45h20 | Departure days Everyday | Cheapest price $147 |
Live departures
St. Louis, MO to San Francisco, CA bus times
The table below shows live departures for St. Louis, MO to San Francisco, CA buses for today, Wednesday, October 28. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 8:40 AM St. Louis, S 15th St (Civic center) | 48h30 | 7:10 AM San Francisco, Transit Center Bay 29 | 2 transfers | |
| · +FlixBus | 8:40 AM St. Louis, S 15th St (Civic center) | 50h05 | 8:45 AM San Francisco, Townsend Street / 5th Street, CA | 2 transfers | |
| · · | 9:10 AM St. Louis, Lambert International Airport | 48h00 | 7:10 AM San Francisco, Transit Center Bay 29 | 2 transfers | |
| · +FlixBus | 9:10 AM St. Louis, Lambert International Airport | 49h35 | 8:45 AM San Francisco, Townsend Street / 5th Street, CA | 2 transfers | |
| · · | 5:15 PM St. Louis, S 15th St (Civic center) | 45h20 | 12:35 PM San Francisco, Transit Center Bay 29 | 2 transfers |
Find all the dates and times for this journey
Why should you book St. Louis, MO to San Francisco, CA buses with Omio?
Greyhound operates all buses services from St. Louis, MO to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to San Francisco, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to San Francisco, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to San Francisco, CA.
Bus providers: Greyhound from St. Louis, MO to San Francisco, CAYou can travel by bus between St. Louis, MO to San Francisco, CA with Greyhound for as low as $132 (€111). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
44h 10m
Cheapest Greyhound Price
$132 (€111)
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between St. Louis, MO and San Francisco, CA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from St. Louis, MO to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between St. Louis, MO and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to San Francisco, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to San Francisco, CA for bus company Greyhound.
Whether you can cancel your bus ticket from St. Louis, MO to San Francisco, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from St. Louis, MO to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to San Francisco, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to San Francisco, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to San Francisco, CA.
You can reserve your seat on the bus from St. Louis, MO to San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to San Francisco, CA with the following bus company: Greyhound.
Complete guide to San Francisco, CA
Things to do in San Francisco, CA
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
- Must visit
de Young Museum
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
- Must visit
San Francisco Museum of Modern Art
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
- Must visit
Golden Gate Park
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
- Must visit
Lombard Street
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
- Must visit
The Embarcadero
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
- Vegetarian
- Vegan
San Francisco Sourdough
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
- Gluten-free
Dungeness Crab
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
Cioppino
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Benu
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Sotto Mare
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
La Taqueria
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
US Dollar ($)
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Average meal costs
- Budget
- $12-20 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $90+ per person for upscale dining.
- Coffee
- $4-7 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Plan your visit to San Francisco, CA
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Francisco, CA.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from St. Louis, MO to San Francisco, CA
Find answers to the most common questions about traveling from St. Louis, MO to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Francisco, CA including taking a bus, train, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from St. Louis, MO to San Francisco, CA
Most St. Louis, MO to San Francisco, CA buses use the St. Louis, S 15th St (Civic center) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare St. Louis, MO and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in San Francisco
Which St. Louis, MO station do buses to San Francisco, CA leave from?
Buses from St. Louis, MO to San Francisco, CA leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $2 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $30 · every ~4 min
St. Louis, Lambert International Airport bus station facilities and services
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options available in terminals.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Tickets and information
Ticket office support is available at St. Louis, Lambert International Airport.
Parking, taxis and toilets
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Which San Francisco, CA station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to San Francisco, CA most often arrive at San Francisco, Transit Center Bay 29. Some services arrive at San Francisco, Townsend Street / 5th Street, so check your ticket before travel to confirm your San Francisco, CA arrival station.
San Francisco, Transit Center Bay 29Transit Center Bay 29, San Francisco, CA 94105, USA
City-centre transport
Getting to San Francisco, Transit Center Bay 29 from San Francisco city centre
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
Bus397 · 8m · $3
14, 14R · 13m · $3 · every ~30 min
101, 120 · 14m · $6 · every ~9 min
7 · 21m · $3 · every ~10 min
SubwayYellow-N, Green-N, Red-N, Blue-N · 10m · $3 · every ~27 min
San Francisco, Transit Center Bay 29 bus station facilities and services
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Tickets and information
Ticket office support is available at San Francisco, Transit Center Bay 29.
Parking, taxis and toilets
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
San Francisco, Townsend Street / 5th StreetSan Francisco Bus Station,401 Townsend St,94107
City-centre transport
Getting to San Francisco, Townsend Street / 5th Street from San Francisco city centre
BusEast, West · 20m · every ~4 min
Nbus, Nowl · 24m · $3 · every ~2 min
TramN · 23m · $3 · every ~11 min
Bus stations for St. Louis, MO to San Francisco, CA
Check bus stations information for St. Louis, MO and San Francisco, CA, including where buses depart and arrive on this route.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in San Francisco, CA , you can end your journey in bus stations like San Francisco, Transit Center Bay 29, San Francisco, Townsend Street / 5th Street .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at San Francisco, Transit Center Bay 29, located 3 away from the city centre.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Francisco, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Francisco, CA and St. Louis, MO
Most popular bus connections to San Francisco, CA
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