St. Louis, MO to San Francisco, CA bus with Greyhound

Thu, Dec 11
+ Add return
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from St. Louis, MO to San Francisco, CA

Showing times and prices for Dec 11

Cheapest price

$200

Average price

$200

Fastest journey

2 d 1 h 50 m

Average duration

2 d 1 h 50 m

Buses per day

1

Distance

2803 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to San Francisco, CA will cost around $200 if you buy it on the day, but the cheapest tickets can be found for only $200.

Fast buses

Of the 1 buses that leave St. Louis, MO for San Francisco, CA on Thu, Dec 11, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Thu, Dec 11 the direct buses cover the 2803 km distance in an average of 2 d 1 h 50 m but if you time it right, some buses will get you there in just 2 d 1 h 50 m .

On Thu, Dec 11 the slowest buses will take 2 d 1 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
12:25PM49h50
St. Louis, MO
02:15PMSan Francisco, CA
$2001One-way
0 transfers

Travel Information

Compare bus, train, and flight for St. Louis, MO to San Francisco, CA

Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €130. For those with little time consider booking a flight which can get you there in 11h 50m. The ticket price range depends on the travel mode: a bus costs an average of €130, and a train costs an average of €183.

Distance: 1741 miles (2803 km)

Compare bus with

Bus
Most popular
Train
Flight

€163

Average price

Cheapest

€277

Average price

€201

Average price

49h 25m

Average total duration

48h 55m

Onboard

+

30m

Additional time*

59h 0m

Average total duration

58h 30m

Onboard

+

30m

Additional time*

14h 50m

Average total duration

Fastest

11h 50m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

St. Louis, MO to San Francisco, CA bus times

The table below shows live departures for St. Louis, MO to San Francisco, CA buses for tomorrow, Thursday, December 11. You can also manually refresh the results below to see updated bus journeys.

Last updated at 8:10 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:25 PM St. Louis, MO
49h50
2:15 PM San Francisco, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Dec 11
Fri
Dec 12
Sat
Dec 13
Sun
Dec 14
Mon
Dec 15
Tue
Dec 16
Wed
Dec 17

Journey information

Overview: Bus from St. Louis, MO to San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to San Francisco, CA run on average 10 times per day, taking around 48h 55m. Cheap bus tickets for this journey start at $162 (€130) if you book in advance.

The earliest bus runs at 04:55, the last at 23:25. The fastest bus covers the 1741 miles (2803 km) distance in 45h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1741 miles (2803 km)
Average bus duration
48h 55m
Cheapest ticket price
$162 (€130)
Buses per day
10
Fastest bus
45h 55m
First bus
04:55
Last bus
23:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from St. Louis, MO to San Francisco, CAYou can travel by bus between St. Louis, MO to San Francisco, CA with Greyhound for as low as $162 (€130). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
45h 55m
Cheapest Price
$162 (€130)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from St. Louis, MO to San Francisco, CA

Find answers to the most common questions about traveling from St. Louis, MO to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to San Francisco, CA can start from as little as $166 (€134) when you book in advance. The average bus ticket price for St. Louis, MO to San Francisco, CA is $341 (€274); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to San Francisco, CA is 49 h 5 min   to travel the 1737 mile (2802 km) long trip, with around there are 8 buses per day. Journey times can vary on weekends and holidays.
The first bus from St. Louis, MO to San Francisco, CA leaves at 12: 30AM. Plan your trip with the Journey Planner   from Omio.
The last bus from St. Louis, MO to San Francisco, CA leaves at 11: 30PM.
There are 8 buses a day from St. Louis, MO to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus providers who offer a service from St. Louis, MO to San Francisco, CA and compare the amenities they offer before buying a bus ticket.
The cheapest month to travel from St. Louis, MO to San Francisco, CA by bus is December.
It's helpful to compare your options as there are 3 ways to travel to San Francisco, CA from St. Louis, MO including taking a bus, train or flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to San Francisco, CA for bus company Greyhound.
Some of the most interesting sights to explore in San Francisco, CA are:
  • Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
  • Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
  • Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
  • Golden Gate Park, a large urban park with gardens, museums, and recreational activities
  • Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
  • Ride a cable car through the steep streets of San Francisco for a classic city experience
  • Explore the vibrant murals and street art in the Mission District
  • Visit the Exploratorium, an interactive science museum perfect for all ages
  • Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
  • Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from St. Louis, MO to San Francisco, CA depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from St. Louis, MO to San Francisco, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from St. Louis, MO to San Francisco, CA.
    Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to San Francisco, CA:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to San Francisco, CA:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from St. Louis, MO to San Francisco, CA.
    You can reserve your seat on the bus from St. Louis, MO to San Francisco, CA with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from St. Louis, MO to San Francisco, CA with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from St. Louis, MO to San Francisco, CA with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from St. Louis, MO to San Francisco, CA

    St. Louis
    San Francisco
    The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to San Francisco.
    St. Louis, S 15th St (Civic center)
    information
    St. Louis, Lambert International Airport
    information

    More options for your journey from St. Louis, MO to San Francisco, CA

    Here are some other resources that might have the information you need

    Most popular buses to and from San Francisco, CA and St. Louis, MO

    HomeBusesBuses in USABus tickets to San Francisco, CASt. Louis, MO to San Francisco, CA bus

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone