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Travel Information
Compare train, bus, and flight for St. Louis, MO to San Diego, CA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €120. For those with little time consider booking a flight which can get you there in 8h 8m. The ticket price range depends on the travel mode: a bus costs an average of €120, and a train costs an average of €193.
Distance: 1560 miles (2512 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€206 Average price Cheapest | €291 Average price | €258 Average price |
51h 34m Average total duration 51h 4m Onboard + 30m Additional time* | 60h 3m Average total duration 59h 33m Onboard + 30m Additional time* | 11h 8m Average total duration Fastest 8h 8m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
St. Louis, MO to San Diego, CA bus times
The table below shows live departures for St. Louis, MO to San Diego, CA buses for today, Saturday, December 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 9:00 PM St. Louis, MO | 51h45 | 12:45 AM San Diego, CA | 0 transfersDirect | |
| 9:30 PM St. Louis, MO | 49h40 | 11:10 PM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from St. Louis, MO to San Diego, CA
USAUSA
Buses from St. Louis, MO to San Diego, CA run on average 14 times per day, taking around 51h 4m. Cheap bus tickets for this journey start at $149 (€120) but you can travel from only $123 (€99) by flight.
The earliest bus runs at 01:35, the last at 19:35. The fastest bus covers the 1560 miles (2512 km) distance in 42h 35m.
Distance 1560 miles (2512 km) |
Average bus duration 51h 4m |
Cheapest ticket price $149 (€120) |
Buses per day 14 |
Fastest bus 42h 35m |
First bus 01:35 |
Last bus 19:35 |
Bus providers: Greyhound from St. Louis, MO to San Diego, CAYou can travel by bus between St. Louis, MO to San Diego, CA with Greyhound for as low as $123 (€99). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to San Diego, CA
Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- Enjoy a harbor cruise for stunning views of the skyline and naval ships
- Hike the scenic trails at Torrey Pines State Natural Reserve
- Visit the Birch Aquarium to learn about marine life and ocean conservation
- Experience the thrill of a whale watching tour off the coast.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from St. Louis, MO to San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to San Diego, CA
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and St. Louis, MO
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