- Must visit
Museum of Fine Arts, Houston
One of America’s top fine arts museums, spanning antiquity to modern works. A must for major collections, architecture, and rotating exhibitions.
Cheapest price
$135
Average price
$148
Fastest journey
20 h 40 m
Average duration
22 h 31 m
Buses per day
6
Distance
1094 km
The best way to find a cheap bus ticket from St. Louis, MO to Houston, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Houston, TX will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $135.
It's difficult to get from St. Louis, MO to Houston, TX without transferring at least 2 times.
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· · Omio recommends booking the train as it is the most popular option from St. Louis, MO to Houston, TX among Omio's users. If you are prioritising price take the train with prices starting from $122. For those with little time consider booking a flight which can get you there in 2h 38m. The ticket price range depends on the travel mode: a train costs an average of $122, and a flight costs an average of $165.
Distance: 679 miles (1094 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$195 Average price | $164 Average price Cheapest | $408 Average price | $156 Average price (fuel + tolls) |
24h 58m Average total duration 24h 28m Onboard + 30m Additional time* | 18h 5m Average total duration 17h 35m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* | 12h 6m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Houston, TX:
A train is $31 (€26) less than a bus for this route with tickets for a bus from St. Louis, MO to Houston, TX costing on average $195 (€160).
A train is $244 (€201) less than a flight for this route with tickets for a flight from St. Louis, MO to Houston, TX costing on average $408 (€336).
Other travel options to Houston, TX take longer:
Train takes on average 17h 35m.
Bus takes on average 24h 28m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 05:05AM | Duration 28h05 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $116 |
Operator Greyhound | Departure Time 01:20AM | Arrival Time 10:50PM | Duration 21h30 | Departure days Everyday | Cheapest price $118 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 05:40PM | Duration 32h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $123 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 12:15PM | Duration 20h15 | Departure days Everyday | Cheapest price $110 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 05:40PM | Duration 24h25 | Departure days Everyday | Cheapest price $103 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 11:30PM | Duration 23h45 | Departure days Everyday | Cheapest price $103 |
The table below shows live departures for St. Louis, MO to Houston, TX buses for today, Tuesday, July 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 4:00 PM St. Louis, S 15th St (Civic center) | 20h40 | 12:40 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
FlixBus+ + + FlixBus | 4:00 PM St. Louis, S 15th St (Civic center) | 22h00 | 2:00 PM Houston, Gray St Parking (Bus Station), TX | 3 transfers | |
· · | 5:15 PM St. Louis, S 15th St (Civic center) | 24h40 | 5:55 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
· · | 11:45 PM St. Louis, S 15th St (Civic center) | 23h45 | 11:30 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
| Wednesday, July 22 | |||||
· · | 1:20 AM St. Louis, S 15th St (Civic center) | 21h30 | 10:50 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
+ FlixBus+![]() | 9:10 AM St. Louis, Lambert International Airport | 32h45 | 5:55 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Houston, TX run on average 9 times per day, taking around 24h 28m. Cheap bus tickets for this journey start at $97 (€79) if you book in advance.
The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 679 miles (1094 km) distance in 20h 0m.
Distance 679 miles (1094 km) |
Average bus duration 24h 28m |
Cheapest ticket price $97 (€79) |
Buses per day 9 |
Fastest bus 20h 0m |
First bus 12:05 AM |
Last bus 11:45 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 42 days |
Discover the best of Houston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Houston trip today.
One of America’s top fine arts museums, spanning antiquity to modern works. A must for major collections, architecture, and rotating exhibitions.
Premier space museum with spacecraft, simulators, and NASA history. Essential for understanding Houston’s link to human spaceflight.
Large natural science museum known for dinosaurs, gems, and immersive displays. A family favorite with broad appeal and strong exhibits.
Houston’s signature urban park with skyline views, events, lawns, and public art. A central gathering place for visitors and locals.
Museum District green space with trails, gardens, and major attractions nearby. Ideal for a scenic walk between Houston’s top institutions.
Former rail corridor turned urban trail with art, landscaping, and skyline glimpses. A modern favorite for walking and casual exploration.
Slow-smoked beef brisket with a peppery bark. Central Texas barbecue is a Houston staple thanks to the city’s strong smokehouse culture.
Spiced beef or chicken fajitas served sizzling with onions and peppers. Houston helped popularize Tex-Mex restaurant fajitas nationwide.
Warm flour tortillas filled with breakfast staples like egg, potato, bacon, or chorizo. A daily Houston favorite shaped by Texas Mexican food culture.
Refined Gulf Coast fine dining with polished service and seasonal seafood. One of Houston’s most acclaimed upscale restaurants.
Highly regarded barbecue spot serving brisket, ribs, and sausage in a simple, old-school setting loved by locals and visitors.
Beloved casual Vietnamese restaurant famous for garlic noodles, shaken beef, and fusion dishes that reflect Houston’s diverse food scene.
Moderate for U.S. cities: hotels vary widely, dining is reasonable, and car-based transit can add costs for visitors.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or card prompts.
Official public transport app
University of Houston / UH South -> Central Station Main, Houston, TX
Find answers to the most common questions about traveling from St. Louis, MO to Houston, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Houston, TX, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Houston, TX buses use the St. Louis, S 15th St (Civic center) to Houston, Harrisburg Blvd (Greyhound Bus Station) station pair, with some services arriving at Houston, Gray St Parking (Bus Station). Use this guide to compare St. Louis, MO and Houston, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need