- Must visit
Cincinnati Art Museum
A major art museum with broad global collections, strong Cincinnati ties, and free admission, set in scenic Eden Park.
Cheapest price on Sep 06
$59
Average ticket price on Sep 06
$64
Fastest journey on Sep 06
10 h 15 m
Average journey duration on Sep 06
11 h 41 m
Buses on Sep 06
7
Distance
495 km
The best way to find a cheap bus ticket from St. Louis, MO to Cincinnati, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Cincinnati, OH will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $59.
It's difficult to get from St. Louis, MO to Cincinnati, OH without transferring at least once.
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FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from St. Louis, MO to Cincinnati, OH among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $60 For those with little time, consider booking a flight, which has an average total journey time of 7h 45m. Average ticket prices depend on the travel mode: a bus costs an average of $60, while a train costs an average of $345.
Distance: 307 miles (495 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$60 Average price Cheapest | $345 Average price | $254 Average price | $72 Average price (fuel + tolls) |
8h 3m Average total duration 7h 33m Onboard + 30m Additional time* | 18h 47m Average total duration 18h 17m Onboard + 30m Additional time* | 7h 45m Average total duration Fastest 5h 45m Onboard + 2h 0m Additional time* | 5h 4m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Cincinnati, OH:
A bus is $195 (€157) less than a flight for this route with tickets for a flight from St. Louis, MO to Cincinnati, OH costing on average $254 (€205).
A bus is $285 (€230) less than a train for this route with tickets for a train from St. Louis, MO to Cincinnati, OH costing on average $345 (€278).
Other travel options to Cincinnati, OH take longer:
Bus takes on average 7h 33m.
Train takes on average 18h 17m.
Tickets start at around $60 (€48) compared to roughly $72 (€58) in fuel and tolls — a saving of about $12 (€10). The journey takes 7h 33m versus 5h 4m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 01:55PM | Duration 10h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $48 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 04:05AM | Duration 13h20 | Departure days Thu, Sun | Cheapest price $48 |
Operator Greyhound | Departure Time 02:05PM | Arrival Time 04:05AM | Duration 13h00 | Departure days Mon, Fri, Sat | Cheapest price $61 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 07:55AM | Duration 13h00 | Departure days Tue | Cheapest price $56 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 02:25PM | Duration 13h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $56 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 05:25PM | Duration 16h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $48 |
The table below shows live departures for St. Louis, MO to Cincinnati, OH buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 2:00 AM St. Louis, S 15th St (Civic center) | 10h15 | 1:15 PM Cincinnati, Greyhound Bus Station, OH | 1 transfer | |
+ FlixBus | 2:00 AM St. Louis, S 15th St (Civic center) | 10h55 | 1:55 PM Cincinnati, Gilbert Ave (Greyhound Bus Station), OH | 1 transfer | |
+ FlixBus | 2:00 AM St. Louis, S 15th St (Civic center) | 10h20 | 1:20 PM Cincinnati, Short Vine St (University of Cincinnati), OH | 1 transfer | |
· · | 2:05 PM St. Louis, S 15th St (Civic center) | 13h00 | 4:05 AM Cincinnati, Greyhound Bus Station, OH | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Cincinnati, OH run on average 5 times per day, taking around 7h 33m. Cheap bus tickets for this journey start at $47 (€38) if you book in advance.
The earliest bus runs at 00:55, the last at 23:30. The fastest bus covers the 307 miles (495 km) distance in 9h 40m.
Distance 307 miles (495 km) |
Average bus duration 7h 33m |
Cheapest ticket price $47 (€38) |
Buses per day 5 |
Fastest bus 9h 40m |
First bus 12:55 AM |
Last bus 11:30 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Fri |
Discover the best of Cincinnati, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cincinnati, OH trip today.
A major art museum with broad global collections, strong Cincinnati ties, and free admission, set in scenic Eden Park.
A family-focused museum inside Union Terminal featuring Cincinnati history, natural history, and rotating science and culture exhibits.
A nationally significant museum preserving Underground Railroad history through immersive exhibits on freedom and civil rights.
The city’s signature riverfront park offers fountains, swings, events, and excellent skyline views along the Ohio River.
A lively historic district known for preserved 19th-century architecture, murals, shops, and one of the best urban walks in Cincinnati.
A civic square lined with historic buildings and event spaces, central to downtown festivals, markets, and everyday city life.
Cincinnati chili is a spiced meat sauce served over spaghetti or hot dogs, then topped with cheese. It is the city's most iconic comfort food.
Goetta is a German-American loaf of pork, beef, oats, and spices, sliced and fried crisp. It reflects the city's strong German heritage.
A cheese coney is a small hot dog in a bun topped with Cincinnati chili, mustard, onions, and shredded cheddar. It is a beloved local quick meal.
Beloved local chain serving ice cream made by the French Pot method. A must for Cincinnati's signature black raspberry chocolate chip.
Refined Midwestern restaurant known for seasonal tasting menus, polished service, and one of Cincinnati's top fine dining experiences.
Historic chili parlor famed for Cincinnati chili, cheese coneys, and a classic local diner feel in the Camp Washington area.
Moderate for U.S. city breaks: hotels are often cheaper than larger metros, dining is mid-priced, and public transit is limited so rideshares or parking can add costs.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or cafe order if service is good.
Find answers to the most common questions about traveling from St. Louis, MO to Cincinnati, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cincinnati, OH, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Cincinnati, OH buses use the St. Louis, S 15th St (Civic center) to Cincinnati, Greyhound Bus Station station pair, with some services arriving at Cincinnati, Short Vine St (University of Cincinnati). Use this guide to compare St. Louis, MO and Cincinnati, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Cincinnati, Greyhound Bus Station is 12 km from Cincinnati city centre. Public transport options include:
Cincinnati, Greyhound Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are aTM machines available inside the station.
Ticket office support is available at Cincinnati, Greyhound Bus Station.
Available at Cincinnati, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Greyhound Bus Station: Wheelchair accessible entrances and seating available.
Cincinnati, Short Vine St (University of Cincinnati) is 3 km from Cincinnati city centre. Public transport options include:
Cincinnati, Short Vine St (University of Cincinnati) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Restaurants available along Short Vine St.
Wi-Fi is available at Cincinnati, Short Vine St (University of Cincinnati). ATMs are aTMs available in nearby banks.
Ticket office support is available at Cincinnati, Short Vine St (University of Cincinnati).
Available at Cincinnati, Short Vine St (University of Cincinnati): Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Short Vine St (University of Cincinnati): Accessible pathways available.
Cincinnati, Gilbert Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Cincinnati, Gilbert Ave (Greyhound Bus Station). ATMs are available at Cincinnati, Gilbert Ave (Greyhound Bus Station).
Ticket office support is available at Cincinnati, Gilbert Ave (Greyhound Bus Station).
Available at Cincinnati, Gilbert Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Gilbert Ave (Greyhound Bus Station): Wheelchair accessible facility.
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