- Must visit
Phoenix Art Museum
A leading Southwestern art museum with major collections of American, Latin American, Asian, and Western works in Downtown Phoenix.
Cheapest price
$294
Average price
$353
Fastest journey
1 d 5 h 30 m
Average duration
1 d 9 h 38 m
Buses per day
5
Distance
2044 km
The best way to find a cheap bus ticket from St. Louis, MO to Phoenix, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Phoenix, AZ will cost around $353 if you buy it on the day, but the cheapest tickets can be found for only $294.
Of the 5 buses that leave St. Louis, MO for Phoenix, AZ on Fri, Jul 31, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 31 the direct buses cover the 2044 km distance in an average of 1 d 9 h 38 m but if you time it right, some buses will get you there in just 1 d 5 h 30 m .
On Fri, Jul 31 the slowest buses will take 1 d 14 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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· · Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Phoenix, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $126. For those with little time consider booking a flight which can get you there in 4h 20m. The ticket price range depends on the travel mode: a bus costs an average of $126, and a flight costs an average of $116.
Distance: 1270 miles (2044 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$218 Average price Cheapest | $452 Average price | $332 Average price | $307 Average price (fuel + tolls) |
30h 34m Average total duration 30h 4m Onboard + 30m Additional time* | 7h 20m Average total duration Fastest 4h 20m Onboard + 3h 0m Additional time* | 52h 5m Average total duration 51h 35m Onboard + 30m Additional time* | 21h 26m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Phoenix, AZ:
A bus is $114 (€93) less than a train for this route with tickets for a train from St. Louis, MO to Phoenix, AZ costing on average $332 (€272).
A bus is $234 (€192) less than a flight for this route with tickets for a flight from St. Louis, MO to Phoenix, AZ costing on average $452 (€371).
Other travel options to Phoenix, AZ take longer:
Bus takes on average 30h 4m.
Train takes on average 51h 35m.
Tickets start at around $218 (€179) compared to roughly $307 (€252) in fuel and tolls — a saving of about $89 (€73). The journey takes 30h 4m versus 21h 26m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20AM | Arrival Time 06:10AM | Duration 30h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $313 |
Operator Greyhound | Departure Time 08:40AM | Arrival Time 12:40PM | Duration 30h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $246 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 12:40PM | Duration 29h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $246 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 07:40PM | Duration 30h00 | Departure days Wed | Cheapest price $209 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 08:40PM | Duration 29h30 | Departure days Wed | Cheapest price $186 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 06:10AM | Duration 38h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $293 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 12:40PM | Duration 38h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $222 |
The table below shows live departures for St. Louis, MO to Phoenix, AZ buses for today, Thursday, July 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:40 AM St. Louis, S 15th St (Civic center) | 30h00 | 12:40 PM Phoenix, Bus Station (E Buckeye Rd) | 0 transfersDirect | |
![]() | 9:10 AM St. Louis, Lambert International Airport | 29h30 | 12:40 PM Phoenix, Bus Station (E Buckeye Rd) | 0 transfersDirect | |
· · | 5:15 PM St. Louis, S 15th St (Civic center) | 38h55 | 6:10 AM Phoenix, Bus Station (E Buckeye Rd) | 2 transfers | |
· · | 11:45 PM St. Louis, S 15th St (Civic center) | 38h55 | 12:40 PM Phoenix, Bus Station (E Buckeye Rd) | 2 transfers | |
| Friday, July 31 | |||||
![]() | 1:20 AM St. Louis, S 15th St (Civic center) | 30h50 | 6:10 AM Phoenix, Bus Station (E Buckeye Rd) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Phoenix, AZ run on average 5 times per day, taking around 30h 4m. Cheap bus tickets for this journey start at $126 (€103) but you can travel from only $116 (€96) by flight.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 1270 miles (2044 km) distance in 29h 30m.
Distance 1270 miles (2044 km) |
Average bus duration 30h 4m |
Cheapest ticket price $126 (€103) |
Buses per day 5 |
Direct buses 2 |
Fastest bus 29h 30m |
First bus 12:05 AM |
Last bus 11:45 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 21 days |
Discover the best of Phoenix, AZ — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Phoenix, AZ trip today.
A leading Southwestern art museum with major collections of American, Latin American, Asian, and Western works in Downtown Phoenix.
An immersive museum of musical instruments from around the world, with audio exhibits, concerts, and broad family appeal.
A major Indigenous art museum presenting Native American and First Nations works, history, and contemporary voices.
A vast desert garden with thousands of cactus species, seasonal blooms, and scenic trails that define the Sonoran landscape.
Phoenix’s signature mountain preserve offers summit hikes, panoramic city views, and one of the region’s most iconic outdoor experiences.
A giant urban park with hiking, biking, desert scenery, and lookouts, making it a favorite for both visitors and locals.
A Sonoran-style hot dog wrapped in bacon and topped with beans, onion, tomato, mayo, mustard, and jalapeño salsa. A Phoenix favorite with roots in nearby Sonora.
Deep-fried burrito commonly filled with shredded beef or chicken, then topped with sauce and cheese. It is a classic Arizona-Mexican comfort dish.
Stewed pinto beans, often cooked creamy and savory. A staple across Phoenix Mexican and Sonoran tables, usually served as a side with many local meals.
Upscale restaurant by a Native American chef highlighting Indigenous Arizona ingredients like tepary beans, cholla buds, and mesquite in a modern setting.
Beloved casual spot known for Sonoran hot dogs and other Tucson-style street food. Lively, no-frills, and one of Phoenix's iconic local bites.
Popular casual chain born in Phoenix, famous for green chile pork and simple Sonoran-style Mexican fare. Fast, reliable, and widely loved by locals.
Moderate for U.S. city breaks: hotels vary by season, dining is mid-priced, and car costs often matter more than public transit.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 per drink or coffee in cafes.
Find answers to the most common questions about traveling from St. Louis, MO to Phoenix, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Phoenix, AZ, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Phoenix, AZ buses use the St. Louis, S 15th St (Civic center) to Phoenix, Bus Station (E Buckeye Rd) station pair, with some services arriving at Phoenix, Sky Train Station. Use this guide to compare St. Louis, MO and Phoenix, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need