St. Louis, MO to Boston, MA bus with Greyhound

Mon, Sep 14
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FlixBus
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from St. Louis, MO to Boston, MA

Showing times, prices and bookable tickets for Sep 14

Cheapest price on Sep 14

$109

Average ticket price on Sep 14

$115

Fastest journey on Sep 14

1 d 6 h 30 m

Average journey duration on Sep 14

1 d 6 h 54 m

Buses on Sep 14

4

Distance

1667 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Boston, MA will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $109.

Fast buses

It's difficult to get from St. Louis, MO to Boston, MA without transferring at least once.

  • Greyhound+FlixBusFlixBus · FlixBus
    8:45 AM30h30
    St. Louis, S 15th St (Civic center)
    4:15 PMBoston, Bus Terminal South Station
    $1091One-way
    2 transfers
  • FlixBusFlixBus+Greyhound ·
    10:00 AM31h25
    St. Louis, S 15th St (Civic center)
    6:25 PMBoston, Bus Terminal South Station
    $1101One-way
    2 transfers
  • Greyhound ·
    2:05 PM30h45
    St. Louis, S 15th St (Civic center)
    9:50 PMBoston, Bus Terminal South Station
    $1111One-way
    1 transfer
  • Greyhound+FlixBusFlixBus
    2:00 AM30h55
    St. Louis, S 15th St (Civic center)
    9:55 AMBoston, Bus Terminal South Station
    $1301One-way
    1 transfer

Travel Information

Compare train, bus, and flight for St. Louis, MO to Boston, MA

Omio recommends booking the train as it is the most popular option from St. Louis, MO to Boston, MA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $226 For those with little time, consider booking a flight, which has an average total journey time of 6h 34m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.5 - 1.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $226, while a train costs an average of $727.

Distance: 1035 miles (1667 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$226

Average price

Cheapest

$727

Average price

$612

Average price

$301

Average price

(fuel + tolls)

29h 55m

Average total duration

29h 25m

Onboard

+

30m

Additional time*

30h 8m

Average total duration

29h 38m

Onboard

+

30m

Additional time*

6h 34m

Average total duration

Fastest

4h 34m

Onboard

+

2h 0m

Additional time*

17h 44m

Average total duration

(door-to-door)

1.7 - 4.2kg

CO2 emissions

0.5 - 1.5kg

CO2 emissions

Lowest

5.0 - 10.0kg

CO2 emissions

-

CO2 emissions

Greyhound

Most popular bus company

Amtrak

Most popular train company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from St. Louis, MO to Boston, MA is a bus with an average price of $226.

This is compared to other travel options from St. Louis, MO to Boston, MA:

A bus is $386 less than a flight for this route with tickets for a flight from St. Louis, MO to Boston, MA costing on average $612.

A bus is $501 less than a train for this route with tickets for a train from St. Louis, MO to Boston, MA costing on average $727.

The fastest way to travel from St. Louis, MO to Boston, MA is by flight with an average journey time of 4h 34m.

Other travel options to Boston, MA take longer:

Bus takes on average 29h 25m.

Train takes on average 29h 38m.

It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Boston, MA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Boston, MA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $226 compared to roughly $301 in fuel and tolls — a saving of about $75. The journey takes 29h 25m versus 17h 44m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

St. Louis, MO to Boston, MA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
02:00AM
Arrival Time
09:55AM
Duration
30h55
Departure days
Everyday
Cheapest price
$99
Operator
Greyhound
Departure Time
08:45AM
Arrival Time
03:10PM
Duration
29h25
Departure days
Everyday
Cheapest price
$108
Operator
Greyhound
Departure Time
10:00AM
Arrival Time
06:25PM
Duration
31h25
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$99
Operator
Greyhound
Departure Time
02:05PM
Arrival Time
09:50PM
Duration
30h45
Departure days
Everyday
Cheapest price
$99

Live departures

St. Louis, MO to Boston, MA bus times

The table below shows live departures for St. Louis, MO to Boston, MA buses for today, Sunday, September 13. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound+FlixBusFlixBus8:45 AM St. Louis, S 15th St (Civic center)
29h25
3:10 PM Boston, Bus Terminal South Station1 transfer
FlixBusFlixBus+Greyhound · 10:00 AM St. Louis, S 15th St (Civic center)
31h25
6:25 PM Boston, Bus Terminal South Station2 transfers
Greyhound · 2:05 PM St. Louis, S 15th St (Civic center)
30h45
9:50 PM Boston, Bus Terminal South Station1 transfer
Monday, September 14
Greyhound+FlixBusFlixBus2:00 AM St. Louis, S 15th St (Civic center)
30h55
9:55 AM Boston, Bus Terminal South Station1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Boston, MA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Sep 14
Tue
Sep 15
Wed
Sep 16
Thu
Sep 17
Fri
Sep 18
Sat
Sep 19
Sun
Sep 20

Why should you book St. Louis, MO to Boston, MA buses with Omio?

Greyhound as well as FlixBus offer buses services from St. Louis, MO to Boston, MA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Boston, MA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Boston, MA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Boston, MA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Boston, MA.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Boston, MA.

Journey information

Overview: Bus from St. Louis, MO to Boston, MA

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to Boston, MA run on average 4 times per day, taking around 29h 25m. Cheap bus tickets for this journey start at $110 if you book in advance.

The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 1035 miles (1667 km) distance in 26h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1035 miles (1667 km)
Average bus duration
29h 25m
Cheapest ticket price
$110
Buses per day
4
Fastest bus
26h 15m
First bus
1:30 AM
Last bus
11:30 PM
Cheapest Month
Apr
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Jul - Sep
Busiest Day
Sat
Least Busy Day
Sat
Best time to book
1 day
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from St. Louis, MO to Boston, MAYou can travel by bus between St. Louis, MO to Boston, MA with Greyhound, FlixBus for as low as $110. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
34h 0m
Cheapest FlixBus Price
$256
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
26h 15m
Cheapest Greyhound Price
$110
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Boston, MA

Things to do in Boston, MA

Discover the best of Boston, MA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston, MA trip today.

  • Must visit

Museum of Fine Arts, Boston

Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.

  • Must visit

Isabella Stewart Gardner Museum

Unique museum displaying Isabella Stewart Gardner's art collection in a Venetian-style palace with a beautiful courtyard.

  • Must visit

Museum of Science

Hands-on science museum on the Charles River, popular for interactive exhibits, live presentations, and family-friendly learning.

US dollar ($)

Boston is pricier than many US cities. Hotels, dining, and attractions add up fast, though transit is manageable and budget food options exist.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$25-45 per person for a mid-range restaurant meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$3-6 for drip coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, more for excellent service. Taxis: 10-15%. Cafes: round up or add $1 per drink.

FAQs: Bus from St. Louis, MO to Boston, MA

Find answers to the most common questions about traveling from St. Louis, MO to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to Boston, MA can start from as little as $110 when you book in advance. The average bus ticket price for St. Louis, MO to Boston, MA is $226 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Boston, MA is 26h 15m to travel the 1035 miles (1667 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Boston, MA leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Boston, MA leaves at 11:30 PM.
There are 4 buses a day from St. Louis, MO to Boston, MA which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Boston, MA, you can count on Greyhound, FlixBus for the best way to get you to Boston, MA. You can also check all possible bus companies who offer a service between St. Louis, MO and Boston, MA and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in Boston, MA , you can end your journey in bus stations like Boston, Bus Terminal South Station, Brookline, Harvard St (Coolidge Corner Opticians), MA, Cambridge, Steel Place, MA .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Boston, Bus Terminal South Station, located 0 away from the city centre.
A trip to Boston, MA from St. Louis, MO is worth doing but not as a day trip with a journey time of 26h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Boston, MA is April.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Boston, MA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Boston, MA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Boston, MA for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Boston, MA are:
  • Best sights: Freedom Trail, a 2.5-mile-long path through downtown Boston that passes by 16 significant historical sites
  • Fenway Park, the iconic baseball stadium and home of the Boston Red Sox
  • Museum of Fine Arts, one of the largest art museums in the United States with an extensive collection of artworks
  • Boston Common, the oldest public park in the United States offering green space and historical landmarks
  • New England Aquarium, a popular attraction featuring a wide variety of marine life and interactive exhibits.
The best things to do in Boston, MA include:
  • Things to do: Explore the historic streets of Beacon Hill, known for its charming cobblestone streets and Federal-style rowhouses
  • Take a scenic walk along the Charles River Esplanade, offering beautiful views of the Boston skyline
  • Visit the Boston Public Library, a stunning architectural landmark with impressive collections and exhibits
  • Enjoy a guided tour of the historic USS Constitution, the world's oldest commissioned naval vessel still afloat
  • Discover the vibrant atmosphere of Quincy Market, with its diverse food stalls and unique shops.
Whether you can cancel your bus ticket from St. Louis, MO to Boston, MA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Boston, MA.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Boston, MA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Boston, MA:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Boston, MA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Boston, MA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Boston, MA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Boston, MA with the following bus company: Greyhound, FlixBus.
Since neither St. Louis, MO nor Boston, MA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Boston, MA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Boston, MA, travelers should be aware of pickpocketing and bag theft, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and overcharging by unlicensed taxi drivers. It's advisable to use official transportation services, stay alert in busy areas, and avoid sharing personal information with strangers to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from St. Louis, MO to Boston, MA

Most St. Louis, MO to Boston, MA buses use the St. Louis, S 15th St (Civic center) to Boston, Bus Terminal South Station station pair. Use this guide to compare St. Louis, MO and Boston, MA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in Boston

Which St. Louis, MO station do buses to Boston, MA leave from?

Buses from St. Louis, MO to Boston, MA leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min

St. Louis, S 15th St (Civic center) bus station facilities and services

St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).

Tickets and information

Ticket office support is available at St. Louis, S 15th St (Civic center).

Parking, taxis and toilets

Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.

St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, Lambert International Airport from St. Louis city centre

St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:

TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $31 · every ~4 min

St. Louis, Lambert International Airport bus station facilities and services

St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Multiple dining options available in terminals.

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.

Tickets and information

Ticket office support is available at St. Louis, Lambert International Airport.

Parking, taxis and toilets

Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.

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