- Must visit
Museum of Fine Arts, Boston
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
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The cheapest and fastest buses from St. Louis, MO to Boston, MA
Showing times and prices for Jul 31
Cheapest price
$258
Average price
$374
Fastest journey
1 d 5 h 25 m
Average duration
1 d 6 h 35 m
Buses per day
4
Distance
1667 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Boston, MA will cost around $374 if you buy it on the day, but the cheapest tickets can be found for only $258.
Fast buses
It's difficult to get from St. Louis, MO to Boston, MA without transferring at least once.
FlixBus+
· 10:00 AM31h25St. Louis, S 15th St (Civic center)6:25 PMBoston, Bus Terminal South Station$2581One-way2 transfers- +FlixBus2:00 AM30h45St. Louis, S 15th St (Civic center)9:45 AMBoston, Bus Terminal South Station$3931One-way1 transfer
- · 2:05 PM30h45St. Louis, S 15th St (Civic center)9:50 PMBoston, Bus Terminal South Station$4211One-way1 transfer
- +FlixBus8:45 AM29h25St. Louis, S 15th St (Civic center)3:10 PMBoston, Bus Terminal South Station$4231One-way1 transfer
- +FlixBus8:45 AM29h25St. Louis, S 15th St (Civic center)3:10 PMBoston, Bus Terminal South Station$4231One-way1 transfer
- · 2:05 PM30h45St. Louis, S 15th St (Civic center)9:50 PMBoston, Bus Terminal South Station$4211One-way1 transfer
- +FlixBus2:00 AM30h45St. Louis, S 15th St (Civic center)9:45 AMBoston, Bus Terminal South Station$3931One-way1 transfer
- FlixBus+ · 10:00 AM31h25St. Louis, S 15th St (Civic center)6:25 PMBoston, Bus Terminal South Station$2581One-way2 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to Boston, MA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from $97. For those with little time consider booking a flight which can get you there in 4h 28m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of $97, and a flight costs an average of $137.
Distance: 1035 miles (1667 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$195 Average price Cheapest | $357 Average price | $419 Average price | $294 Average price (fuel + tolls) |
27h 15m Average total duration 26h 45m Onboard + 30m Additional time* | 27h 36m Average total duration 27h 6m Onboard + 30m Additional time* | 7h 28m Average total duration Fastest 4h 28m Onboard + 3h 0m Additional time* | 17h 44m Average total duration (door-to-door) |
1.7 - 4.2kg CO2 emissions | 0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from St. Louis, MO to Boston, MA is a bus with an average price of $195 (€159).
This is compared to other travel options from St. Louis, MO to Boston, MA:
A bus is $162 (€133) less than a train for this route with tickets for a train from St. Louis, MO to Boston, MA costing on average $357 (€292).
A bus is $225 (€184) less than a flight for this route with tickets for a flight from St. Louis, MO to Boston, MA costing on average $419 (€343).
The fastest way to travel from St. Louis, MO to Boston, MA is by flight with an average journey time of 4h 28m.
Other travel options to Boston, MA take longer:
Bus takes on average 26h 45m.
Train takes on average 27h 6m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Boston, MA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Boston, MA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
St. Louis, MO to Boston, MA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 09:45AM | Duration 30h45 | Departure days Everyday | Cheapest price $302 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 03:10PM | Duration 29h25 | Departure days Everyday | Cheapest price $276 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 09:15PM | Duration 59h05 | Departure days Mon | Cheapest price $364 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 06:25PM | Duration 31h25 | Departure days Everyday | Cheapest price $165 |
Operator Greyhound | Departure Time 02:05PM | Arrival Time 09:50PM | Duration 30h45 | Departure days Everyday | Cheapest price $231 |
Live departures
St. Louis, MO to Boston, MA bus times
The table below shows live departures for St. Louis, MO to Boston, MA buses for today, Thursday, July 30. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus | 2:00 AM St. Louis, S 15th St (Civic center) | 30h45 | 9:45 AM Boston, Bus Terminal South Station | 1 transfer | |
| +FlixBus | 8:45 AM St. Louis, S 15th St (Civic center) | 29h25 | 3:10 PM Boston, Bus Terminal South Station | 1 transfer | |
| FlixBus+ · | 10:00 AM St. Louis, S 15th St (Civic center) | 31h25 | 6:25 PM Boston, Bus Terminal South Station | 2 transfers | |
| · | 2:05 PM St. Louis, S 15th St (Civic center) | 30h45 | 9:50 PM Boston, Bus Terminal South Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Boston, MA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Boston, MA buses with Omio?
Greyhound as well as FlixBus offer buses services from St. Louis, MO to Boston, MA.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Boston, MA.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Boston, MA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Boston, MA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Boston, MA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Boston, MA.
Journey information
Overview: Bus from St. Louis, MO to Boston, MA
USAUSA
Buses from St. Louis, MO to Boston, MA run on average 4 times per day, taking around 26h 45m. Cheap bus tickets for this journey start at $97 (€79) if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 1035 miles (1667 km) distance in 29h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1035 miles (1667 km) |
Average bus duration 26h 45m |
Cheapest ticket price $97 (€79) |
Buses per day 4 |
Fastest bus 29h 25m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 3 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from St. Louis, MO to Boston, MAYou can travel by bus between St. Louis, MO to Boston, MA with Greyhound, FlixBus for as low as $97 (€79). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
29h 25m
Cheapest Price
$97 (€79)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Boston, MA
Things to do in Boston, MA
Discover the best of Boston, MA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston, MA trip today.
- Must visit
Isabella Stewart Gardner Museum
Unique museum displaying Isabella Stewart Gardner's art collection in a Venetian-style palace with a beautiful courtyard.
- Must visit
Museum of Science
Hands-on science museum on the Charles River, popular for interactive exhibits, live presentations, and family-friendly learning.
- Must visit
Freedom Trail
Historic brick-lined route connecting key revolutionary sites, ideal for first-time visitors seeking Boston's core story on foot.
- Must visit
Boston Public Garden
Elegant public garden famous for swan boats, seasonal flowers, and postcard views in the heart of downtown Boston.
- Must visit
Faneuil Hall Marketplace
Historic market district and pedestrian-friendly area known for street life, shops, performers, and easy downtown exploring.
New England Clam Chowder
Creamy New England chowder with clams, potatoes, and salt pork. It is a defining Boston seafood dish tied to the city's maritime history.
Lobster Roll
Hot dog bun split on top and filled with chilled lobster meat, usually with butter or mayo. A classic New England summer seafood staple.
Baked Scrod
Baked cod topped with buttery crumbs, often with lemon. It reflects Boston's long cod fishing tradition and old-school Yankee cooking.
Row 34
Elegant fine-dining destination by the waterfront known for pristine seafood, tasting menus, and one of Boston's top culinary reputations.
Giacomo's Ristorante
Classic North End Italian restaurant famous for generous portions, old-school service, and beloved Boston dining tradition.
Saltie Girl
Refined seafood restaurant and oyster bar with polished service, excellent raw bar options, and a Back Bay setting.
US dollar ($)
Boston is pricier than many US cities. Hotels, dining, and attractions add up fast, though transit is manageable and budget food options exist.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a mid-range restaurant meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $3-6 for drip coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for excellent service. Taxis: 10-15%. Cafes: round up or add $1 per drink.
FAQs: Bus from St. Louis, MO to Boston, MA
Find answers to the most common questions about traveling from St. Louis, MO to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Boston, MA can start from as little as $97 (€79) when you book in advance. The average bus ticket price for St. Louis, MO to Boston, MA is $195 (€159) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Boston, MA is 29h 25m to travel the 1035 miles (1667 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Boston, MA leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Boston, MA leaves at 11:30 PM.
There are 4 buses a day from St. Louis, MO to Boston, MA which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Boston, MA, you can count on Greyhound, FlixBus for the best way to get you to Boston, MA. You can also check all possible bus companies who offer a service between St. Louis, MO and Boston, MA and compare the amenities they offer before buying a bus ticket.
A trip to Boston, MA from St. Louis, MO is worth doing but not as a day trip with a journey time of 29h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Boston, MA is April.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Boston, MA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Boston, MA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Boston, MA for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Boston, MA are:
- Best sights: Freedom Trail, a 2.5-mile-long path through downtown Boston that passes by 16 significant historical sites
- Fenway Park, the iconic baseball stadium and home of the Boston Red Sox
- Museum of Fine Arts, one of the largest art museums in the United States with an extensive collection of artworks
- Boston Common, the oldest public park in the United States offering green space and historical landmarks
- New England Aquarium, a popular attraction featuring a wide variety of marine life and interactive exhibits.
The best things to do in Boston, MA include:
- Things to do: Explore the historic streets of Beacon Hill, known for its charming cobblestone streets and Federal-style rowhouses
- Take a scenic walk along the Charles River Esplanade, offering beautiful views of the Boston skyline
- Visit the Boston Public Library, a stunning architectural landmark with impressive collections and exhibits
- Enjoy a guided tour of the historic USS Constitution, the world's oldest commissioned naval vessel still afloat
- Discover the vibrant atmosphere of Quincy Market, with its diverse food stalls and unique shops.
Whether you can cancel your bus ticket from St. Louis, MO to Boston, MA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Boston, MA.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Boston, MA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Boston, MA:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Boston, MA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Boston, MA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Boston, MA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Boston, MA with the following bus company: Greyhound, FlixBus.
Since neither St. Louis, MO nor Boston, MA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Boston, MA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Boston, MA, travelers should be aware of pickpocketing and bag theft, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and overcharging by unlicensed taxi drivers. It's advisable to use official transportation services, stay alert in busy areas, and avoid sharing personal information with strangers to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Boston, MA
Most St. Louis, MO to Boston, MA buses use the St. Louis, S 15th St (Civic center) to Boston, Bus Terminal South Station station pair. Use this guide to compare St. Louis, MO and Boston, MA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Boston
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, Lambert International Airport
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $31 · every ~4 min
Boston, Bus Terminal South Station
City-centre transport
Getting to Boston, Bus Terminal South Station from Boston city centre
SubwayRed Line · 2m · $4 · every ~26 min
Red Line · 4m · $4 · every ~26 min
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Boston, MA
Here are some other resources that might have the information you need
Most popular buses to and from Boston, MA and St. Louis, MO
Most popular bus connections to Boston, MA
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