- Must visit
Museum of Fine Arts, Boston
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
Cheapest price on Sep 14
$109
Average ticket price on Sep 14
$115
Fastest journey on Sep 14
1 d 6 h 30 m
Average journey duration on Sep 14
1 d 6 h 54 m
Buses on Sep 14
4
Distance
1667 km
The best way to find a cheap bus ticket from St. Louis, MO to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Boston, MA will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $109.
It's difficult to get from St. Louis, MO to Boston, MA without transferring at least once.
+
FlixBus · FlixBus
FlixBus+
·
·
+
FlixBus
+
FlixBus · FlixBus
·
+
FlixBus
FlixBus+
· Omio recommends booking the train as it is the most popular option from St. Louis, MO to Boston, MA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $226 For those with little time, consider booking a flight, which has an average total journey time of 6h 34m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.5 - 1.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $226, while a train costs an average of $727.
Distance: 1035 miles (1667 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$226 Average price Cheapest | $727 Average price | $612 Average price | $301 Average price (fuel + tolls) |
29h 55m Average total duration 29h 25m Onboard + 30m Additional time* | 30h 8m Average total duration 29h 38m Onboard + 30m Additional time* | 6h 34m Average total duration Fastest 4h 34m Onboard + 2h 0m Additional time* | 17h 44m Average total duration (door-to-door) |
1.7 - 4.2kg CO2 emissions | 0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to Boston, MA:
A bus is $386 less than a flight for this route with tickets for a flight from St. Louis, MO to Boston, MA costing on average $612.
A bus is $501 less than a train for this route with tickets for a train from St. Louis, MO to Boston, MA costing on average $727.
Other travel options to Boston, MA take longer:
Bus takes on average 29h 25m.
Train takes on average 29h 38m.
Tickets start at around $226 compared to roughly $301 in fuel and tolls — a saving of about $75. The journey takes 29h 25m versus 17h 44m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 09:55AM | Duration 30h55 | Departure days Everyday | Cheapest price $99 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 03:10PM | Duration 29h25 | Departure days Everyday | Cheapest price $108 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 06:25PM | Duration 31h25 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $99 |
Operator Greyhound | Departure Time 02:05PM | Arrival Time 09:50PM | Duration 30h45 | Departure days Everyday | Cheapest price $99 |
The table below shows live departures for St. Louis, MO to Boston, MA buses for today, Sunday, September 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 8:45 AM St. Louis, S 15th St (Civic center) | 29h25 | 3:10 PM Boston, Bus Terminal South Station | 1 transfer | |
FlixBus+ · | 10:00 AM St. Louis, S 15th St (Civic center) | 31h25 | 6:25 PM Boston, Bus Terminal South Station | 2 transfers | |
· | 2:05 PM St. Louis, S 15th St (Civic center) | 30h45 | 9:50 PM Boston, Bus Terminal South Station | 1 transfer | |
| Monday, September 14 | |||||
+ FlixBus | 2:00 AM St. Louis, S 15th St (Civic center) | 30h55 | 9:55 AM Boston, Bus Terminal South Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Boston, MA run on average 4 times per day, taking around 29h 25m. Cheap bus tickets for this journey start at $110 if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 1035 miles (1667 km) distance in 26h 15m.
Distance 1035 miles (1667 km) |
Average bus duration 29h 25m |
Cheapest ticket price $110 |
Buses per day 4 |
Fastest bus 26h 15m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 1 day |
Discover the best of Boston, MA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston, MA trip today.
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
Unique museum displaying Isabella Stewart Gardner's art collection in a Venetian-style palace with a beautiful courtyard.
Hands-on science museum on the Charles River, popular for interactive exhibits, live presentations, and family-friendly learning.
Historic brick-lined route connecting key revolutionary sites, ideal for first-time visitors seeking Boston's core story on foot.
Elegant public garden famous for swan boats, seasonal flowers, and postcard views in the heart of downtown Boston.
Historic market district and pedestrian-friendly area known for street life, shops, performers, and easy downtown exploring.
Creamy New England chowder with clams, potatoes, and salt pork. It is a defining Boston seafood dish tied to the city's maritime history.
Hot dog bun split on top and filled with chilled lobster meat, usually with butter or mayo. A classic New England summer seafood staple.
Baked cod topped with buttery crumbs, often with lemon. It reflects Boston's long cod fishing tradition and old-school Yankee cooking.
Elegant fine-dining destination by the waterfront known for pristine seafood, tasting menus, and one of Boston's top culinary reputations.
Classic North End Italian restaurant famous for generous portions, old-school service, and beloved Boston dining tradition.
Refined seafood restaurant and oyster bar with polished service, excellent raw bar options, and a Back Bay setting.
Boston is pricier than many US cities. Hotels, dining, and attractions add up fast, though transit is manageable and budget food options exist.
Tip 18-20% at restaurants, more for excellent service. Taxis: 10-15%. Cafes: round up or add $1 per drink.
Find answers to the most common questions about traveling from St. Louis, MO to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Boston, MA buses use the St. Louis, S 15th St (Civic center) to Boston, Bus Terminal South Station station pair. Use this guide to compare St. Louis, MO and Boston, MA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Boston, Bus Terminal South Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food and cafe options available.
Free Wi-Fi available throughout the terminal. ATMs are aTMs located inside the terminal.
Ticket office support is available at Boston, Bus Terminal South Station.
Available at Boston, Bus Terminal South Station: Parking, Taxis, WC.
Accessibility facilities are available at Boston, Bus Terminal South Station: Fully accessible with ramps and elevators.
Here are some other resources that might have the information you need