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Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
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The cheapest and fastest buses from St. Louis, MO to Orlando, FL
Showing times, prices and bookable tickets for Oct 10
Cheapest price on Oct 10
$105
Average ticket price on Oct 10
$110
Fastest journey on Oct 10
19 h 15 m
Average journey duration on Oct 10
22 h 51 m
Buses on Oct 10
7
Distance
1386 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Orlando, FL will cost around $110 if you buy it on the day, but the cheapest tickets can be found for only $105.
Fast buses
It's difficult to get from St. Louis, MO to Orlando, FL without transferring at least once.
· · +
FlixBus1:45 PM26h35St. Louis, S 15th St (Civic center)5:20 PMOrlando, The Florida Mall, FL$1051One-way3 transfers- FlixBus · FlixBus11:45 PM23h14St. Louis, S 15th St (Civic center)11:59 PMOrlando, The Florida Mall, FL$1061One-way1 transfer
- FlixBus+ · 4:00 PM23h20St. Louis, S 15th St (Civic center)4:20 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1071One-way2 transfers
- · +FlixBus1:00 AM27h50St. Louis, S 15th St (Civic center)5:50 AMOrlando, N John Young Pkwy (Greyhound Bus Station)$1081One-way2 transfers
- FlixBus · FlixBus11:45 PM19h15St. Louis, S 15th St (Civic center)8:00 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1091One-way1 transfer
- FlixBus · FlixBus11:45 PM19h15St. Louis, S 15th St (Civic center)8:00 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1091One-way1 transfer
- +FlixBus9:00 AM21h50St. Louis, S 15th St (Civic center)7:50 AMOrlando, N John Young Pkwy (Greyhound Bus Station)$1091One-way1 transfer
- FlixBus · FlixBus11:45 PM23h14St. Louis, S 15th St (Civic center)11:59 PMOrlando, The Florida Mall, FL$1061One-way1 transfer
- FlixBus+ · 4:00 PM23h20St. Louis, S 15th St (Civic center)4:20 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1071One-way2 transfers
- · · +FlixBus1:45 PM26h35St. Louis, S 15th St (Civic center)5:20 PMOrlando, The Florida Mall, FL$1051One-way3 transfers
Journey information
Overview: Bus from St. Louis, MO to Orlando, FL
USAUSA
Buses from St. Louis, MO to Orlando, FL run on average 6 times per day, taking around 20h 55m. Cheap bus tickets for this journey start at $86 (€72) but you can travel from only $80 (€67) by flight.
The earliest bus runs at 01:00, the last at 23:45. The fastest bus covers the 861 miles (1386 km) distance in 18h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $80 (€67)
Distance 861 miles (1386 km) |
Average bus duration 20h 55m |
Cheapest ticket price $86 (€72) |
Buses per day 6 |
Fastest bus 18h 30m |
First bus 1:00 AM |
Last bus 11:45 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 42 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $80 (€67)
St. Louis, MO to Orlando, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:00AM | Arrival Time 05:50AM | Duration 27h50 | Departure days Everyday | Cheapest price $98 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 02:55PM | Duration 28h55 | Departure days Everyday | Cheapest price $101 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 05:20PM | Duration 26h35 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 02:05PM | Arrival Time 11:59PM | Duration 32h54 | Departure days Wed | Cheapest price $108 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 04:20PM | Duration 23h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $98 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 08:00PM | Duration 19h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $94 |
Live departures
St. Louis, MO to Orlando, FL bus times
The table below shows live departures for St. Louis, MO to Orlando, FL buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · +FlixBus | 1:00 AM St. Louis, S 15th St (Civic center) | 27h50 | 5:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 2 transfers | |
| +FlixBus · FlixBus | 9:00 AM St. Louis, S 15th St (Civic center) | 28h55 | 2:55 PM Orlando, The Florida Mall, FL | 2 transfers | |
| +FlixBus | 9:00 AM St. Louis, S 15th St (Civic center) | 21h50 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
| · · +FlixBus | 1:45 PM St. Louis, S 15th St (Civic center) | 26h35 | 5:20 PM Orlando, The Florida Mall, FL | 3 transfers | |
| FlixBus+ · | 4:00 PM St. Louis, S 15th St (Civic center) | 23h20 | 4:20 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 2 transfers |
Find all the dates and times for this journey
Why should you book St. Louis, MO to Orlando, FL buses with Omio?
Greyhound as well as FlixBus offer buses services from St. Louis, MO to Orlando, FL.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Orlando, FL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Orlando, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Orlando, FL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Orlando, FL.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Orlando, FL.
Bus providers: Greyhound, FlixBus from St. Louis, MO to Orlando, FLYou can travel by bus between St. Louis, MO to Orlando, FL with Greyhound, FlixBus for as low as $80 (€67). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
18h 30m
Cheapest FlixBus Price
$86 (€72)
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
19h 25m
Cheapest Greyhound Price
$86 (€72)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Orlando, FL
Things to do in Orlando, FL
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
- Recommended
Orange County Regional History Center
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
- Recommended
Rollins Museum of Art
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
- Must visit
Lake Eola Park
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
- Must visit
Park Avenue
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
- Recommended
Church Street District
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
Florida Catfish
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
- Gluten-free
Florida Shrimp
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
- Vegetarian
- Vegan
- Gluten-free
Cafecito
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Black Bean Deli
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Linda's La Cantina
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
The Ravenous Pig
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
US Dollar ($)
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Average meal costs
- Budget
- $10-15 for fast food or casual counter service.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
FAQs: Bus from St. Louis, MO to Orlando, FL
Find answers to the most common questions about traveling from St. Louis, MO to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Orlando, FL can start from as little as $86 (€72) when you book in advance. The average bus ticket price for St. Louis, MO to Orlando, FL is $142 (€119) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Orlando, FL is 18h 30m to travel the 861 miles (1386 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Orlando, FL leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Orlando, FL leaves at 11:45 PM.
There are 6 buses a day from St. Louis, MO to Orlando, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Orlando, FL, you can count on Greyhound, FlixBus for the best way to get you to Orlando, FL. You can also check all possible bus companies who offer a service between St. Louis, MO and Orlando, FL and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in Orlando, FL , you can end your journey in bus stations like Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL, Buena Ventura Lakes, Kissimmee .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Orlando, N John Young Pkwy (Greyhound Bus Station), located 3 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Orlando, FL including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Orlando, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Orlando, FL for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from St. Louis, MO to Orlando, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Orlando, FL.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Orlando, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Orlando, FL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Orlando, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Orlando, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Orlando, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Orlando, FL with the following bus company: Greyhound, FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Orlando, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like theme parks and popular tourist spots. Common scams include overpriced taxi rides, timeshare presentations that pressure visitors, and fake ticket sellers near major attractions. It's important to use authorized transportation services and purchase tickets from official vendors to avoid fraud. Additionally, travelers should stay aware of their surroundings and avoid poorly lit or isolated areas at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Orlando, FL
Most St. Louis, MO to Orlando, FL buses use the St. Louis, S 15th St (Civic center) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare St. Louis, MO and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Orlando
Which St. Louis, MO station do buses to Orlando, FL leave from?
Buses from St. Louis, MO to Orlando, FL leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $30 · every ~4 min
St. Louis, Lambert International Airport bus station facilities and services
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options available in terminals.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Tickets and information
Ticket office support is available at St. Louis, Lambert International Airport.
Parking, taxis and toilets
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Which Orlando, FL station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to Orlando, FL most often arrive at Orlando, N John Young Pkwy (Greyhound Bus Station). Some services arrive at Orlando, The Florida Mall, so check your ticket before travel to confirm your Orlando, FL arrival station.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $2 · every ~5 min
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Orlando, FL
Here are some other resources that might have the information you need
Most popular buses to and from Orlando, FL and St. Louis, MO
Most popular bus connections to Orlando, FL
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