- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price
$123
Average price
$128
Fastest journey
19 h 15 m
Average duration
23 h 4 m
Buses per day
4
Distance
1386 km
The best way to find a cheap bus ticket from St. Louis, MO to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Orlando, FL will cost around $128 if you buy it on the day, but the cheapest tickets can be found for only $123.
It's difficult to get from St. Louis, MO to Orlando, FL without transferring at least once.
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FlixBusOmio recommends booking the flight as it is the most popular option from St. Louis, MO to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $100. For those with little time consider booking a flight which can get you there in 3h 24m. The ticket price range depends on the travel mode: a bus costs an average of $100, and a train costs an average of $228.
Distance: 861 miles (1386 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$127 Average price Cheapest | $190 Average price | $490 Average price | $215 Average price (fuel + tolls) |
21h 58m Average total duration 21h 28m Onboard + 30m Additional time* | 6h 24m Average total duration Fastest 3h 24m Onboard + 3h 0m Additional time* | 44h 33m Average total duration 44h 3m Onboard + 30m Additional time* | 14h 29m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Orlando, FL:
A bus is $62 less than a flight for this route with tickets for a flight from St. Louis, MO to Orlando, FL costing on average $190.
A bus is $362 less than a train for this route with tickets for a train from St. Louis, MO to Orlando, FL costing on average $490.
Other travel options to Orlando, FL take longer:
Bus takes on average 21h 28m.
Train takes on average 44h 3m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:00AM | Arrival Time 05:50AM | Duration 27h50 | Departure days Everyday | Cheapest price $119 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 02:55PM | Duration 28h55 | Departure days Everyday | Cheapest price $122 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 05:20PM | Duration 26h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $132 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 04:20PM | Duration 23h20 | Departure days Everyday | Cheapest price $119 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 11:59PM | Duration 23h14 | Departure days Everyday | Cheapest price $115 |
The table below shows live departures for St. Louis, MO to Orlando, FL buses for today, Monday, August 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:45 PM St. Louis, S 15th St (Civic center) | 23h14 | 11:59 PM Orlando, The Florida Mall, FL | 1 transfer | |
FlixBus · FlixBus | 11:45 PM St. Louis, S 15th St (Civic center) | 19h15 | 8:00 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
| Tuesday, August 25 | |||||
FlixBus+ · | 1:00 AM St. Louis, S 15th St (Civic center) | 27h50 | 5:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 2 transfers | |
+ FlixBus | 9:00 AM St. Louis, S 15th St (Civic center) | 21h50 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus+ · | 4:00 PM St. Louis, S 15th St (Civic center) | 23h20 | 4:20 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 2 transfers | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Orlando, FL run on average 6 times per day, taking around 21h 28m. Cheap bus tickets for this journey start at $100 if you book in advance.
The earliest bus runs at 01:00, the last at 23:45. The fastest bus covers the 861 miles (1386 km) distance in 19h 15m.
Distance 861 miles (1386 km) |
Average bus duration 21h 28m |
Cheapest ticket price $100 |
Buses per day 6 |
Fastest bus 19h 15m |
First bus 1:00 AM |
Last bus 11:45 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from St. Louis, MO to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Orlando, FL buses use the St. Louis, S 15th St (Civic center) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare St. Louis, MO and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
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