- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
Cheapest price on Sep 19
$122
Average ticket price on Sep 19
$132
Fastest journey on Sep 19
20 h 55 m
Average journey duration on Sep 19
22 h 25 m
Buses on Sep 19
11
Distance
1276 km
The best way to find a cheap bus ticket from St. Louis, MO to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Antonio, TX will cost around $132 if you buy it on the day, but the cheapest tickets can be found for only $122.
It's difficult to get from St. Louis, MO to San Antonio, TX without transferring at least 2 times.
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Omio recommends booking the flight as it is the most popular option from St. Louis, MO to San Antonio, TX among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $172 For those with little time, consider booking a flight, which has an average total journey time of 6h 34m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.4 - 1.1kg. Average ticket prices depend on the travel mode: a bus costs an average of $172, while a flight costs an average of $494.
Distance: 792 miles (1276 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$172 Average price Cheapest | $494 Average price | $221 Average price | $240 Average price (fuel + tolls) |
22h 21m Average total duration 21h 51m Onboard + 30m Additional time* | 6h 34m Average total duration Fastest 4h 34m Onboard + 2h 0m Additional time* | 27h 5m Average total duration 26h 35m Onboard + 30m Additional time* | 13h 48m Average total duration (door-to-door) |
1.3 - 3.2kg CO2 emissions | 3.8 - 7.7kg CO2 emissions | 0.4 - 1.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to San Antonio, TX:
A bus is $49 (€40) less than a train for this route with tickets for a train from St. Louis, MO to San Antonio, TX costing on average $221 (€181).
A bus is $322 (€264) less than a flight for this route with tickets for a flight from St. Louis, MO to San Antonio, TX costing on average $494 (€404).
Other travel options to San Antonio, TX take longer:
Bus takes on average 21h 51m.
Train takes on average 26h 35m.
Tickets start at around $172 (€141) compared to roughly $240 (€196) in fuel and tolls — a saving of about $68 (€56). The journey takes 21h 51m versus 13h 48m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20AM | Arrival Time 11:55PM | Duration 22h35 | Departure days Everyday | Cheapest price $92 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 06:10PM | Duration 33h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $98 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 12:55PM | Duration 20h55 | Departure days Everyday | Cheapest price $93 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 06:10PM | Duration 24h55 | Departure days Everyday | Cheapest price $93 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 01:15AM | Duration 25h30 | Departure days Everyday | Cheapest price $93 |
The table below shows live departures for St. Louis, MO to San Antonio, TX buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 11:45 PM St. Louis, S 15th St (Civic center) | 25h30 | 1:15 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| Saturday, September 19 | |||||
· · | 1:20 AM St. Louis, S 15th St (Civic center) | 22h35 | 11:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
· · | 1:20 AM St. Louis, S 15th St (Civic center) | 22h45 | 12:05 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
+ FlixBus+![]() | 9:10 AM St. Louis, Lambert International Airport | 33h00 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
+ FlixBus+![]() | 9:10 AM St. Louis, Lambert International Airport | 33h00 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
FlixBus+ +![]() | 4:00 PM St. Louis, S 15th St (Civic center) | 20h55 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
FlixBus+ +![]() | 4:00 PM St. Louis, S 15th St (Civic center) | 20h55 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
· + FlixBus · FlixBus | 5:15 PM St. Louis, S 15th St (Civic center) | 27h10 | 8:25 PM San Antonio, Avenue A / Pearl Pkwy, TX | 3 transfers | |
· +![]() | 5:15 PM St. Louis, S 15th St (Civic center) | 24h55 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
· +![]() | 5:15 PM St. Louis, S 15th St (Civic center) | 24h55 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to San Antonio, TX run on average 5 times per day, taking around 21h 51m. Cheap bus tickets for this journey start at $99 (€81) but you can travel from only $71 (€58) by flight.
The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 792 miles (1276 km) distance in 18h 0m.
Distance 792 miles (1276 km) |
Average bus duration 21h 51m |
Cheapest ticket price $99 (€81) |
Buses per day 5 |
Fastest bus 18h 0m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Find answers to the most common questions about traveling from St. Louis, MO to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to San Antonio, TX buses use the St. Louis, S 15th St (Civic center) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare St. Louis, MO and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options available in terminals.
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Ticket office support is available at St. Louis, Lambert International Airport.
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Here are some other resources that might have the information you need