St. Louis, MO to San Antonio, TX bus with Greyhound

Sat, Sep 19
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The cheapest and fastest buses from St. Louis, MO to San Antonio, TX

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

$122

Average ticket price on Sep 19

$132

Fastest journey on Sep 19

20 h 55 m

Average journey duration on Sep 19

22 h 25 m

Buses on Sep 19

11

Distance

1276 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to San Antonio, TX will cost around $132 if you buy it on the day, but the cheapest tickets can be found for only $122.

Fast buses

It's difficult to get from St. Louis, MO to San Antonio, TX without transferring at least 2 times.

  • Greyhound · +Valley Transit
    5:15 PM24h55
    St. Louis, S 15th St (Civic center)
    6:10 PMSan Antonio, N St Mary's St (Greyhound), TX
    $1221One-way
    2 transfers
  • Greyhound · ·
    11:45 PM25h30
    St. Louis, S 15th St (Civic center)
    1:15 AMSan Antonio, N St Mary's St (Greyhound), TX
    $1231One-way
    2 transfers
  • Greyhound · ·
    1:20 AM22h35
    St. Louis, S 15th St (Civic center)
    11:55 PMSan Antonio, N St Mary's St (Greyhound), TX
    $1231One-way
    2 transfers
  • FlixBusFlixBus+Greyhound+Valley Transit
    4:00 PM20h55
    St. Louis, S 15th St (Civic center)
    12:55 PMSan Antonio, N St Mary's St (Greyhound), TX
    $1231One-way
    2 transfers
  • Greyhound+FlixBusFlixBus+Valley Transit
    9:10 AM33h00
    St. Louis, Lambert International Airport
    6:10 PMSan Antonio, N St Mary's St (Greyhound), TX
    $1321One-way
    2 transfers

Travel Information

Compare train, bus, and flight for St. Louis, MO to San Antonio, TX

Omio recommends booking the flight as it is the most popular option from St. Louis, MO to San Antonio, TX among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $172 For those with little time, consider booking a flight, which has an average total journey time of 6h 34m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.4 - 1.1kg. Average ticket prices depend on the travel mode: a bus costs an average of $172, while a flight costs an average of $494.

Distance: 792 miles (1276 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$172

Average price

Cheapest

$494

Average price

$221

Average price

$240

Average price

(fuel + tolls)

22h 21m

Average total duration

21h 51m

Onboard

+

30m

Additional time*

6h 34m

Average total duration

Fastest

4h 34m

Onboard

+

2h 0m

Additional time*

27h 5m

Average total duration

26h 35m

Onboard

+

30m

Additional time*

13h 48m

Average total duration

(door-to-door)

1.3 - 3.2kg

CO2 emissions

3.8 - 7.7kg

CO2 emissions

0.4 - 1.1kg

CO2 emissions

Lowest

-

CO2 emissions

Greyhound

Most popular bus company

American Airlines

Most popular airline

Amtrak

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from St. Louis, MO to San Antonio, TX is a bus with an average price of $172 (€141).

This is compared to other travel options from St. Louis, MO to San Antonio, TX:

A bus is $49 (€40) less than a train for this route with tickets for a train from St. Louis, MO to San Antonio, TX costing on average $221 (€181).

A bus is $322 (€264) less than a flight for this route with tickets for a flight from St. Louis, MO to San Antonio, TX costing on average $494 (€404).

The fastest way to travel from St. Louis, MO to San Antonio, TX is by flight with an average journey time of 4h 34m.

Other travel options to San Antonio, TX take longer:

Bus takes on average 21h 51m.

Train takes on average 26h 35m.

It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Antonio, TX including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to San Antonio, TX among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $172 (€141) compared to roughly $240 (€196) in fuel and tolls — a saving of about $68 (€56). The journey takes 21h 51m versus 13h 48m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

St. Louis, MO to San Antonio, TX Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:20AM
Arrival Time
11:55PM
Duration
22h35
Departure days
Everyday
Cheapest price
$92
Operator
Greyhound
Departure Time
09:10AM
Arrival Time
06:10PM
Duration
33h00
Departure days
Mon, Tue, Wed, Fri, Sat, Sun
Cheapest price
$98
Operator
Greyhound
Departure Time
04:00PM
Arrival Time
12:55PM
Duration
20h55
Departure days
Everyday
Cheapest price
$93
Operator
Greyhound
Departure Time
05:15PM
Arrival Time
06:10PM
Duration
24h55
Departure days
Everyday
Cheapest price
$93
Operator
Greyhound
Departure Time
11:45PM
Arrival Time
01:15AM
Duration
25h30
Departure days
Everyday
Cheapest price
$93

Live departures

St. Louis, MO to San Antonio, TX bus times

The table below shows live departures for St. Louis, MO to San Antonio, TX buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · · 11:45 PM St. Louis, S 15th St (Civic center)
25h30
1:15 AM San Antonio, N St Mary's St (Greyhound), TX2 transfers
Saturday, September 19
Greyhound · · 1:20 AM St. Louis, S 15th St (Civic center)
22h35
11:55 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers
Greyhound · · 1:20 AM St. Louis, S 15th St (Civic center)
22h45
12:05 AM San Antonio, N St Mary's St (Greyhound), TX2 transfers
Greyhound+FlixBusFlixBus+Valley Transit9:10 AM St. Louis, Lambert International Airport
33h00
6:10 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers
Greyhound+FlixBusFlixBus+Valley Transit9:10 AM St. Louis, Lambert International Airport
33h00
6:10 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers
FlixBusFlixBus+Greyhound+Valley Transit4:00 PM St. Louis, S 15th St (Civic center)
20h55
12:55 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers
FlixBusFlixBus+Greyhound+Valley Transit4:00 PM St. Louis, S 15th St (Civic center)
20h55
12:55 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers
Greyhound · +FlixBusFlixBus · FlixBus5:15 PM St. Louis, S 15th St (Civic center)
27h10
8:25 PM San Antonio, Avenue A / Pearl Pkwy, TX3 transfers
Greyhound · +Valley Transit5:15 PM St. Louis, S 15th St (Civic center)
24h55
6:10 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers
Greyhound · +Valley Transit5:15 PM St. Louis, S 15th St (Civic center)
24h55
6:10 PM San Antonio, N St Mary's St (Greyhound), TX2 transfers

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to San Antonio, TX by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
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Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
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Sep 25

Why should you book St. Louis, MO to San Antonio, TX buses with Omio?

Greyhound operates all buses services from St. Louis, MO to San Antonio, TX.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to San Antonio, TX.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to San Antonio, TX.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to San Antonio, TX.

Journey information

Overview: Bus from St. Louis, MO to San Antonio, TX

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to San Antonio, TX run on average 5 times per day, taking around 21h 51m. Cheap bus tickets for this journey start at $99 (€81) but you can travel from only $71 (€58) by flight.

The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 792 miles (1276 km) distance in 18h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $71 (€58)
Distance
792 miles (1276 km)
Average bus duration
21h 51m
Cheapest ticket price
$99 (€81)
Buses per day
5
Fastest bus
18h 0m
First bus
1:15 AM
Last bus
11:30 PM
Cheapest Month
Jul
Cheapest Day
Tue
High Season
Jul - Sep
Low Season
Oct - Dec
Busiest Day
Sat
Least Busy Day
Sat
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $71 (€58)

Bus providers: Greyhound from St. Louis, MO to San Antonio, TXYou can travel by bus between St. Louis, MO to San Antonio, TX with Greyhound for as low as $71 (€58). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
18h 0m
Cheapest Greyhound Price
$99 (€81)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to San Antonio, TX

Things to do in San Antonio, TX

Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.

  • Must visit

San Antonio Museum of Art

A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.

  • Must visit

McNay Art Museum

This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.

  • Recommended

Contemporary at Blue Star

Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.

U.S. Dollar ($)

Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.

Average meal costs

Budget
$10-$18 for fast food or tacos.
Mid-range
$20-$40 per person for a casual sit-down meal.
Fine dining
$60+ per person for upscale restaurants.
Coffee
$3-$6 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.

FAQs: Bus from St. Louis, MO to San Antonio, TX

Find answers to the most common questions about traveling from St. Louis, MO to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to San Antonio, TX can start from as little as $99 (€81) when you book in advance. The average bus ticket price for St. Louis, MO to San Antonio, TX is $172 (€141) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to San Antonio, TX is 18h 0m to travel the 792 miles (1276 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to San Antonio, TX leaves at 1:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to San Antonio, TX leaves at 11:30 PM.
There are 5 buses a day from St. Louis, MO to San Antonio, TX which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to San Antonio, TX, you can count on Greyhound for the best way to get you to San Antonio, TX. You can also check all possible bus companies who offer a service between St. Louis, MO and San Antonio, TX and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in San Antonio, TX , you can end your journey in bus stations like San Antonio, N St Mary's St (Greyhound), TX, San Antonio, Avenue A / Pearl Pkwy, TX .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at San Antonio, N St Mary's St (Greyhound), TX, located 0 away from the city centre.
A trip to San Antonio, TX from St. Louis, MO is worth doing but not as a day trip with a journey time of 18h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to San Antonio, TX is July.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Antonio, TX including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to San Antonio, TX:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to San Antonio, TX for bus company Greyhound.
Some of the most interesting sights to explore in San Antonio, TX are:
  • The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
  • River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
  • San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
  • San Antonio Museum of Art, housing an extensive collection of art from around the world
  • Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
The best things to do in San Antonio, TX include:
  • Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
  • take a boat tour along the San Antonio River for a unique perspective of the city
  • visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
  • enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
  • experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from St. Louis, MO to San Antonio, TX depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to San Antonio, TX.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to San Antonio, TX:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to San Antonio, TX:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to San Antonio, TX.
You can reserve your seat on the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound.
Since neither St. Louis, MO nor San Antonio, TX are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to San Antonio, TX among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Antonio, TX, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the River Walk and Alamo Plaza. Common scams include overcharging by unofficial taxi services and street vendors. It's advisable to use authorized transportation options and stay alert when approached by strangers offering unsolicited help or tours. Staying in well-lit, busy areas and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from St. Louis, MO to San Antonio, TX

Most St. Louis, MO to San Antonio, TX buses use the St. Louis, S 15th St (Civic center) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare St. Louis, MO and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in San Antonio

Which St. Louis, MO station do buses to San Antonio, TX leave from?

Buses from St. Louis, MO to San Antonio, TX leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min

St. Louis, S 15th St (Civic center) bus station facilities and services

St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).

Tickets and information

Ticket office support is available at St. Louis, S 15th St (Civic center).

Parking, taxis and toilets

Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.

St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, Lambert International Airport from St. Louis city centre

St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:

TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $31 · every ~4 min

St. Louis, Lambert International Airport bus station facilities and services

St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Multiple dining options available in terminals.

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.

Tickets and information

Ticket office support is available at St. Louis, Lambert International Airport.

Parking, taxis and toilets

Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.

Most popular buses to and from San Antonio, TX and St. Louis, MO

HomeBusesBuses in USABus tickets to San Antonio, TXSt. Louis, MO to San Antonio, TX bus

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