- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
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The cheapest and fastest buses from St. Louis, MO to San Antonio, TX
Showing times, prices and bookable tickets for Nov 04
- Cheapest price on Nov 04
- $122
- Average ticket price on Nov 04
- $126
- Fastest journey on Nov 04
- 22 h 45 m
- Average journey duration on Nov 04
- 1 d 3 h 6 m
- Buses on Nov 04
- 5
- Distance
- 1276 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Antonio, TX will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $122.
Fast buses
It's difficult to get from St. Louis, MO to San Antonio, TX without transferring at least 2 times.
· +
5:15 PM 24h55 St. Louis, S 15th St (Civic center) 6:10 PM San Antonio, N St Mary's St (Greyhound), TX $122 1 One-way 2 transfers- · +
FlixBus11:45 PM 26h55 St. Louis, S 15th St (Civic center) 2:40 AM San Antonio, N St Mary's St (Greyhound), TX $123 1 One-way 2 transfers - · +
9:00 AM 27h55 St. Louis, S 15th St (Civic center) 12:55 PM San Antonio, N St Mary's St (Greyhound), TX $123 1 One-way 2 transfers - +FlixBus+
9:10 AM 33h00 St. Louis, Lambert International Airport 6:10 PM San Antonio, N St Mary's St (Greyhound), TX $126 1 One-way 2 transfers - · ·
1:20 AM 22h45 St. Louis, S 15th St (Civic center) 12:05 AM San Antonio, N St Mary's St (Greyhound), TX $137 1 One-way 2 transfers
- · ·
1:20 AM 22h45 St. Louis, S 15th St (Civic center) 12:05 AM San Antonio, N St Mary's St (Greyhound), TX $137 1 One-way 2 transfers - · +
5:15 PM 24h55 St. Louis, S 15th St (Civic center) 6:10 PM San Antonio, N St Mary's St (Greyhound), TX $122 1 One-way 2 transfers - · +FlixBus
11:45 PM 26h55 St. Louis, S 15th St (Civic center) 2:40 AM San Antonio, N St Mary's St (Greyhound), TX $123 1 One-way 2 transfers - · +
9:00 AM 27h55 St. Louis, S 15th St (Civic center) 12:55 PM San Antonio, N St Mary's St (Greyhound), TX $123 1 One-way 2 transfers - +FlixBus+
9:10 AM 33h00 St. Louis, Lambert International Airport 6:10 PM San Antonio, N St Mary's St (Greyhound), TX $126 1 One-way 2 transfers
Journey information
Overview: Bus from St. Louis, MO to San Antonio, TX
USAUSA
Buses from St. Louis, MO to San Antonio, TX run on average 5 times per day, taking around 22h 4m. Cheap bus tickets for this journey start at $83 but you can travel from only $70 by flight.
The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 792 miles (1276 km) distance in 18h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $70
Distance 792 miles (1276 km) |
Average bus duration 22h 4m |
Cheapest ticket price $83 |
Buses per day 5 |
Fastest bus 18h 40m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $70
Frequently asked questions about your St. Louis, MO to San Antonio, TX trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from St. Louis, MO to San Antonio, TX.
Cheap bus tickets from St. Louis, MO to San Antonio, TX can start from as little as $83 when you book in advance. The average bus ticket price for St. Louis, MO to San Antonio, TX is $140 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from St. Louis, MO to San Antonio, TX leaves at 1:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to San Antonio, TX leaves at 11:30 PM.
There are 5 buses a day from St. Louis, MO to San Antonio, TX which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
St. Louis, MO to San Antonio, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 08:25PM | Duration 43h25 | Departure days Tue | Cheapest price $109 |
Operator Greyhound | Departure Time 01:20AM | Arrival Time 12:05AM | Duration 22h45 | Departure days Everyday | Cheapest price $109 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 12:55PM | Duration 27h55 | Departure days Tue, Wed | Cheapest price $108 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 06:10PM | Duration 33h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $113 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 12:55PM | Duration 20h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 06:10PM | Duration 24h55 | Departure days Everyday | Cheapest price $109 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 02:40AM | Duration 26h55 | Departure days Everyday | Cheapest price $109 |
Live departures
St. Louis, MO to San Antonio, TX bus times
The table below shows live departures for St. Louis, MO to San Antonio, TX buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus · FlixBus · FlixBus | 1:00 AM St. Louis, S 15th St (Civic center) | 43h25 | 8:25 PM San Antonio, Avenue A / Pearl Pkwy, TX | 3 transfers | |
| · · | 1:20 AM St. Louis, S 15th St (Civic center) | 22h45 | 12:05 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| · + | 9:00 AM St. Louis, S 15th St (Civic center) | 27h55 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| +FlixBus+ | 9:10 AM St. Louis, Lambert International Airport | 33h00 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| · + | 5:15 PM St. Louis, S 15th St (Civic center) | 24h55 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers |
Find all the dates and times for this journey
Why should you book St. Louis, MO to San Antonio, TX buses with Omio?
Greyhound operates all buses services from St. Louis, MO to San Antonio, TX.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to San Antonio, TX.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to San Antonio, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to San Antonio, TX.
Bus providers: Greyhound from St. Louis, MO to San Antonio, TXYou can travel by bus between St. Louis, MO to San Antonio, TX with Greyhound for as low as $70. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
18h 40m
Cheapest Greyhound Price
$83
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between St. Louis, MO and San Antonio, TX
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from St. Louis, MO to San Antonio, TX, you can count on Greyhound for the best way to get you to San Antonio, TX. You can also check all possible bus companies who offer a service between St. Louis, MO and San Antonio, TX and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to San Antonio, TX:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to San Antonio, TX for bus company Greyhound.
Whether you can cancel your bus ticket from St. Louis, MO to San Antonio, TX depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from St. Louis, MO to San Antonio, TX.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to San Antonio, TX:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to San Antonio, TX:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to San Antonio, TX.
You can reserve your seat on the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound.
Complete guide to San Antonio, TX
Things to do in San Antonio, TX
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
- Must visit
McNay Art Museum
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
- Recommended
Contemporary at Blue Star
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
- Must visit
San Antonio River Walk
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
- Recommended
Southtown
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
- Recommended
Main Plaza
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
- Gluten-free
Puffy Tacos
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
- Gluten-free
Barbacoa
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast Tacos
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Biga on the Banks
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Blanco Cafe
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Mi Tierra Cafe y Panaderia
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
U.S. Dollar ($)
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Average meal costs
- Budget
- $10-$18 for fast food or tacos.
- Mid-range
- $20-$40 per person for a casual sit-down meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $3-$6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
VIA goMobile+
Get the appOfficial public transport app
Prices
- Single ticket
- $1.30
- Day pass
- $2.75
To the city center
UTSA East Campus Lot 1 -> Downtown San Antonio
- Distance
- 21 km
- Travel time
- 24 min
- Tap or insert cash on VIA buses; exact fare is recommended because operators do not give change.
- Use VIA goMobile+ to buy fares before boarding and to plan trips across San Antonio.
Plan your visit to San Antonio, TX
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Antonio, TX.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Antonio, TX, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the River Walk and Alamo Plaza. Common scams include overcharging by unofficial taxi services and street vendors. It's advisable to use authorized transportation options and stay alert when approached by strangers offering unsolicited help or tours. Staying in well-lit, busy areas and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from St. Louis, MO to San Antonio, TX
Find answers to the most common questions about traveling from St. Louis, MO to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Antonio, TX including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from St. Louis, MO to San Antonio, TX
Most St. Louis, MO to San Antonio, TX buses use the St. Louis, S 15th St (Civic center) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare St. Louis, MO and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in San Antonio
Which St. Louis, MO station do buses to San Antonio, TX leave from?
Buses from St. Louis, MO to San Antonio, TX leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $2 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $30 · every ~4 min
St. Louis, Lambert International Airport bus station facilities and services
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options available in terminals.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Tickets and information
Ticket office support is available at St. Louis, Lambert International Airport.
Parking, taxis and toilets
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Which San Antonio, TX station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to San Antonio, TX most often arrive at San Antonio, N St Mary's St (Greyhound). Some services arrive at San Antonio, Avenue A / Pearl Pkwy, so check your ticket before travel to confirm your San Antonio, TX arrival station.
San Antonio, N St Mary's St (Greyhound)500 N St Mary's St, San Antonio, TX 78205, USA
City-centre transport
Getting to San Antonio, N St Mary's St (Greyhound) from San Antonio city centre
TRUE
San Antonio, N St Mary's St (Greyhound) bus station facilities and services
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Tickets and information
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Parking, taxis and toilets
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl PkwyAvenue A & Pearl Pkwy, San Antonio, TX 78215, USA
City-centre transport
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
BusFlixBus 2230 · 11m · $2
10, 14, 214, 9 · 12m · $3 · every ~17 min
San Antonio, Avenue A / Pearl Pkwy bus station facilities and services
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Tickets and information
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Parking, taxis and toilets
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Bus stations for St. Louis, MO to San Antonio, TX
Check bus stations information for St. Louis, MO and San Antonio, TX, including where buses depart and arrive on this route.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in San Antonio, TX , you can end your journey in bus stations like San Antonio, N St Mary's St (Greyhound), San Antonio, Avenue A / Pearl Pkwy .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at San Antonio, N St Mary's St (Greyhound), located 1 away from the city centre.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Antonio, TX
Here are some other resources that might have the information you need
Most popular buses to and from San Antonio, TX and St. Louis, MO
Most popular bus connections to San Antonio, TX
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