- Must visit
The Alamo Exhibit at the Ralston Family Collections Center
Modern museum gallery displaying Alamo artifacts and interpretation beside the historic mission site. A strong companion visit for understanding the 1836 battle and Texas history.
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The cheapest and fastest buses from St. Louis, MO to San Antonio, TX
Showing times and prices for Jun 21
Cheapest price
$130
Average price
$131
Fastest journey
20 h 55 m
Average duration
1 d 49 m
Buses per day
6
Distance
1276 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Antonio, TX will cost around $131 if you buy it on the day, but the cheapest tickets can be found for only $130.
Fast buses
It's difficult to get from St. Louis, MO to San Antonio, TX without transferring at least 2 times.
+
FlixBus+
9:10 AM33h00St. Louis, Lambert International Airport6:10 PMSan Antonio, N St Mary's St (Greyhound), TX$1301One-way2 transfers- FlixBus++4:00 PM20h55St. Louis, S 15th St (Civic center)12:55 PMSan Antonio, N St Mary's St (Greyhound), TX$1301One-way2 transfers
- · +5:15 PM24h55St. Louis, S 15th St (Civic center)6:10 PMSan Antonio, N St Mary's St (Greyhound), TX$1311One-way2 transfers
- · +FlixBus · FlixBus5:15 PM30h10St. Louis, S 15th St (Civic center)11:25 PMSan Antonio, Avenue A / Pearl Pkwy, TX$1321One-way3 transfers
- · · 11:45 PM25h30St. Louis, S 15th St (Civic center)1:15 AMSan Antonio, N St Mary's St (Greyhound), TX$1321One-way2 transfers
- FlixBus++4:00 PM20h55St. Louis, S 15th St (Civic center)12:55 PMSan Antonio, N St Mary's St (Greyhound), TX$1301One-way2 transfers
- · · 1:20 AM22h35St. Louis, S 15th St (Civic center)11:55 PMSan Antonio, N St Mary's St (Greyhound), TX$1321One-way2 transfers
- · +5:15 PM24h55St. Louis, S 15th St (Civic center)6:10 PMSan Antonio, N St Mary's St (Greyhound), TX$1311One-way2 transfers
- · · 11:45 PM25h30St. Louis, S 15th St (Civic center)1:15 AMSan Antonio, N St Mary's St (Greyhound), TX$1321One-way2 transfers
- · +FlixBus · FlixBus5:15 PM30h10St. Louis, S 15th St (Civic center)11:25 PMSan Antonio, Avenue A / Pearl Pkwy, TX$1321One-way3 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to San Antonio, TX
Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Antonio, TX among Omio's users. If you are prioritising price take the train with prices starting from $117. For those with little time consider booking a flight which can get you there in 5h 23m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.4 - 1.1kg. The ticket price range depends on the travel mode: a train costs an average of $117, and a flight costs an average of $107.
Distance: 792 miles (1276 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$178 Average price | $165 Average price Cheapest | $233 Average price | $237 Average price (fuel + tolls) |
22h 12m Average total duration 21h 42m Onboard + 30m Additional time* | 26h 58m Average total duration 26h 28m Onboard + 30m Additional time* | 8h 23m Average total duration Fastest 5h 23m Onboard + 3h 0m Additional time* | 13h 48m Average total duration (door-to-door) |
1.3 - 3.2kg CO2 emissions | 0.4 - 1.1kg CO2 emissions Lowest | 3.8 - 7.7kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from St. Louis, MO to San Antonio, TX is a train with an average price of $165 (€135).
This is compared to other travel options from St. Louis, MO to San Antonio, TX:
A train is $13 (€10) less than a bus for this route with tickets for a bus from St. Louis, MO to San Antonio, TX costing on average $178 (€146).
A train is $68 (€56) less than a flight for this route with tickets for a flight from St. Louis, MO to San Antonio, TX costing on average $233 (€191).
The fastest way to travel from St. Louis, MO to San Antonio, TX is by flight with an average journey time of 5h 23m.
Other travel options to San Antonio, TX take longer:
Bus takes on average 21h 42m.
Train takes on average 26h 28m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Antonio, TX including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from St. Louis, MO to San Antonio, TX among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
St. Louis, MO to San Antonio, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20AM | Arrival Time 11:55PM | Duration 22h35 | Departure days Everyday | Cheapest price $120 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 06:10PM | Duration 33h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $119 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 12:55PM | Duration 20h55 | Departure days Everyday | Cheapest price $118 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 06:10PM | Duration 24h55 | Departure days Everyday | Cheapest price $121 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 01:15AM | Duration 25h30 | Departure days Everyday | Cheapest price $119 |
Live departures
St. Louis, MO to San Antonio, TX bus times
The table below shows live departures for St. Louis, MO to San Antonio, TX buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus++ | 4:00 PM St. Louis, S 15th St (Civic center) | 20h55 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| · + | 5:15 PM St. Louis, S 15th St (Civic center) | 24h55 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| · +FlixBus · FlixBus | 5:15 PM St. Louis, S 15th St (Civic center) | 27h55 | 9:10 PM San Antonio, Avenue A / Pearl Pkwy, TX | 3 transfers | |
| · · | 11:45 PM St. Louis, S 15th St (Civic center) | 25h30 | 1:15 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| Sunday, June 21 | |||||
| · · | 1:20 AM St. Louis, S 15th St (Civic center) | 22h35 | 11:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
| +FlixBus+ | 9:10 AM St. Louis, Lambert International Airport | 33h00 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to San Antonio, TX by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to San Antonio, TX buses with Omio?
Greyhound operates all buses services from St. Louis, MO to San Antonio, TX.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to San Antonio, TX.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to San Antonio, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to San Antonio, TX.
Journey information
Overview: Bus from St. Louis, MO to San Antonio, TX
USAUSA
Buses from St. Louis, MO to San Antonio, TX run on average 5 times per day, taking around 21h 42m. Cheap bus tickets for this journey start at $107 (€88) but you can travel from only $107 (€87) by flight.
The earliest bus runs at 01:15, the last at 23:30. The fastest bus covers the 792 miles (1276 km) distance in 20h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $107 (€87)
Distance 792 miles (1276 km) |
Average bus duration 21h 42m |
Cheapest ticket price $107 (€88) |
Buses per day 5 |
Fastest bus 20h 45m |
First bus 1:15 AM |
Last bus 11:30 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 84 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $107 (€87)
Bus providers: Greyhound from St. Louis, MO to San Antonio, TXYou can travel by bus between St. Louis, MO to San Antonio, TX with Greyhound for as low as $107 (€87). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
20h 45m
Cheapest Price
$107 (€88)
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Antonio
Things to do in San Antonio
Discover the best of San Antonio — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio trip today.
- Must visit
San Antonio Museum of Art
Major art museum with collections spanning ancient Mediterranean works, Asian art, Latin American art, and contemporary pieces in a historic brewery complex.
- Recommended
The Witte Museum
Leading regional museum focused on Texas history, natural science, and South Texas heritage, with engaging family-friendly exhibits and strong local context.
- Must visit
San Antonio River Walk
The city’s signature pedestrian waterfront lined with bridges, public art, and walking paths. It is the most recognizable area in San Antonio.
- Recommended
Historic Market Square
Large public square and cultural district known for Mexican-American heritage, shops, events, and festive open-air atmosphere.
- Recommended
Pearl District
Trendy mixed-use district in a former brewery area, popular for architecture, river access, and stylish public spaces.
- Gluten-free
Puffy Tacos
A San Antonio specialty made with freshly fried, puffed corn tortilla shells filled with picadillo, chicken, or beans, then topped with lettuce, cheese, and salsa.
- Gluten-free
Barbacoa
Slow-cooked beef, traditionally served very tender on weekends in tacos with onion, cilantro, and salsa. It is one of the city’s most beloved breakfast foods.
Breakfast Tacos
A daily staple in San Antonio, usually made with flour or corn tortillas filled with eggs, beans, potato, bacon, chorizo, or cheese.
Bliss
Well-regarded upscale restaurant serving refined New American cuisine in a stylish yet relaxed setting south of Downtown.
The Original Donut Shop
Popular casual spot famous for oversized breakfast tacos, donuts, and classic San Antonio morning fare.
Mi Tierra Cafe y Panaderia
Iconic Market Square institution known for classic Tex-Mex, bakery items, mariachi atmosphere, and colorful decor.
United States Dollar
Generally moderate for U.S. city travel. Budget eats are easy to find, while hotels and attractions vary by season and area.
Average meal costs
- Budget
- USD 10-18 for tacos, fast food, or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at sit-down restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff a few USD.
FAQs: Bus from St. Louis, MO to San Antonio, TX
Find answers to the most common questions about traveling from St. Louis, MO to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to San Antonio, TX can start from as little as $107 (€88) when you book in advance. The average bus ticket price for St. Louis, MO to San Antonio, TX is $178 (€146) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to San Antonio, TX is 20h 45m to travel the 792 miles (1276 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to San Antonio, TX leaves at 1:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to San Antonio, TX leaves at 11:30 PM.
There are 5 buses a day from St. Louis, MO to San Antonio, TX which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to San Antonio, TX, you can count on Greyhound for the best way to get you to San Antonio, TX. You can also check all possible bus companies who offer a service between St. Louis, MO and San Antonio, TX and compare the amenities they offer before buying a bus ticket.
A trip to San Antonio, TX from St. Louis, MO is worth doing but not as a day trip with a journey time of 20h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to San Antonio, TX is January.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and San Antonio, TX including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to San Antonio, TX:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to San Antonio, TX for bus company Greyhound.
Some of the most interesting sights to explore in San Antonio, TX are:
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
The best things to do in San Antonio, TX include:
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- take a boat tour along the San Antonio River for a unique perspective of the city
- visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from St. Louis, MO to San Antonio, TX depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to San Antonio, TX.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to San Antonio, TX:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to San Antonio, TX:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to San Antonio, TX.
You can reserve your seat on the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to San Antonio, TX with the following bus company: Greyhound.
Since neither St. Louis, MO nor San Antonio, TX are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to San Antonio, TX among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Antonio, TX, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the River Walk and Alamo Plaza. Common scams include overcharging by unofficial taxi services and street vendors. It's advisable to use authorized transportation options and stay alert when approached by strangers offering unsolicited help or tours. Staying in well-lit, busy areas and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to San Antonio, TX
Most St. Louis, MO to San Antonio, TX buses use the St. Louis, S 15th St (Civic center) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare St. Louis, MO and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in San Antonio
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, Lambert International Airport
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $31 · every ~4 min
San Antonio, N St Mary's St (Greyhound)
San Antonio, Avenue A / Pearl Pkwy
City-centre transport
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
BusFlixBus 2230 · 11m · $1
10, 14, 214, 9 · 12m · $2 · every ~17 min
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Antonio, TX
Here are some other resources that might have the information you need
Most popular buses to and from San Antonio, TX and St. Louis, MO
Most popular bus connections to San Antonio, TX
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