4.9
4.6
Travel Information
Compare bus, train, and flight for St. Louis, MO to Milwaukee, WI
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Milwaukee, WI among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €61 For those with little time, consider booking a flight, which has an average total journey time of 5h 55m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €61, while a flight costs an average of €509.
Distance: 327 miles (527 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€141 Average price | €61 Average price Cheapest | €509 Average price | €67 Average price (fuel + tolls) |
7h 20m Average total duration 6h 50m Onboard + 30m Additional time* | 9h 18m Average total duration 8h 48m Onboard + 30m Additional time* | 5h 55m Average total duration Fastest 3h 55m Onboard + 2h 0m Additional time* | 5h 17m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | 1.6 - 3.2kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from St. Louis, MO to Milwaukee, WI
Compare the available ways to get from St. Louis, MO to Milwaukee, WI, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from St. Louis, MO to Milwaukee, WI:
A bus is €81 less than a train for this route with tickets for a train from St. Louis, MO to Milwaukee, WI costing on average €141.
A bus is €448 less than a flight for this route with tickets for a flight from St. Louis, MO to Milwaukee, WI costing on average €509.
Other travel options to Milwaukee, WI take longer:
Train takes on average 7h 20m.
Bus takes on average 9h 18m.
Tickets start at around €141 compared to roughly €67 in fuel and tolls — a saving of about -€74. The journey takes 6h 50m versus 5h 17m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom St. Louis, MO to Milwaukee, WI
How to get from St. Louis, MO to Milwaukee, WI by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Milwaukee, WI is by taking a bus because it’s the best combination of price and speed.
- FlixBus · FlixBus
10:00 AM 8h45 St. Louis, S 15th St (Civic center) 6:45 PM Milwaukee, Intermodal Station €48 1 One-way 1 transfer
Cheapest
- FlixBus · FlixBus
10:00 AM 8h45 St. Louis, S 15th St (Civic center) 6:45 PM Milwaukee, Intermodal Station €48 1 One-way 1 transfer
Fastest
- UA5973 · UA3519
5:26 PM 3h24 St. Louis Lambert International Airport 8:50 PM General Mitchell International Airport €183 1 One-way 1 transfer
Other options
- FlixBus+
11:30 PM 9h00 St. Louis, S 15th St (Civic center) 8:30 AM Milwaukee, Intermodal Station €48 1 One-way 1 transfer - FlixBus · FlixBus
10:00 AM 8h25 St. Louis, S 15th St (Civic center) 6:25 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI €49 1 One-way 1 transfer - FlixBus · FlixBus
11:30 PM 11h05 St. Louis, S 15th St (Civic center) 10:35 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI €49 1 One-way 1 transfer
AA1926+
AA49197:26 AM 3h42 St. Louis Lambert International Airport 11:08 AM General Mitchell International Airport €153 1 One-way 1 transfer
AA3484+AA49925:29 PM 5h08 St. Louis Lambert International Airport 10:37 PM General Mitchell International Airport €153 1 One-way 1 transfer- AA4919+AA3409
6:00 AM 5h08 St. Louis Lambert International Airport 11:08 AM General Mitchell International Airport €153 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from St. Louis, MO to Milwaukee, WI
Travel to Milwaukee, WI easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Milwaukee, WI.
This is compared to other travel options from St. Louis, MO to Milwaukee, WI:
A bus is €81 less than a train for this route with tickets for a train from St. Louis, MO to Milwaukee, WI costing on average €141.
A bus is €448 less than a flight for this route with tickets for a flight from St. Louis, MO to Milwaukee, WI costing on average €509.
Other travel options to Milwaukee, WI take longer:
Train takes on average 7h 20m.
Bus takes on average 9h 18m.
- Around 52 flights per day.
- Around 9 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between St. Louis, MO and Milwaukee, WI as scheduled services by bus, train, and flight can vary by season or day of the week.
- Buses mostly depart from St. Louis, S 15th St (Civic center) and arrive in Milwaukee, Intermodal Station.
- Trains mostly depart from St. Louis Station, St. Louis, MO and arrive in Milwaukee Intermodal Station, Milwaukee, WI.
- Flights mostly depart from St. Louis Lambert International Airport and arrive in General Mitchell International Airport.
- Travel with Amtrak to go to Milwaukee, WI by train.
- Travel with FlixBus, Greyhound to go to Milwaukee, WI by bus.
- Travel with United, American Airlines, skywest airlines, psa airlines, Republic Airlines, piedmont airlines to go to Milwaukee, WI by flight.
Travelling from St. Louis, MO to Milwaukee, WI: related information
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