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Travel Information
Compare bus, train, and flight for St. Louis, MO to Milwaukee, WI
Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Milwaukee, WI among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $81 For those with little time, consider booking a flight, which has an average total journey time of 5h 51m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $81, while a flight costs an average of $617.
Distance: 327 miles (527 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$617 Average price | $168 Average price | $81 Average price Cheapest | $81 Average price (fuel + tolls) |
5h 51m Average total duration Fastest 3h 51m Onboard + 2h 0m Additional time* | 7h 19m Average total duration 6h 49m Onboard + 30m Additional time* | 9h 21m Average total duration 8h 51m Onboard + 30m Additional time* | 5h 17m Average total duration (door-to-door) |
1.6 - 3.2kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | - CO2 emissions |
 Most popular airline |  Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from St. Louis, MO to Milwaukee, WI:
A bus is $88 less than a train for this route with tickets for a train from St. Louis, MO to Milwaukee, WI costing on average $168.
A bus is $536 less than a flight for this route with tickets for a flight from St. Louis, MO to Milwaukee, WI costing on average $617.
Other travel options to Milwaukee, WI take longer:
Train takes on average 7h 19m.
Bus takes on average 9h 21m.
You'll arrive about 1h 26m sooner (3h 51m by flight vs 5h 17m by car). Tickets start at around $617 compared to roughly $81 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom St. Louis, MO to Milwaukee, WI
How to get from St. Louis, MO to Milwaukee, WI by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Milwaukee, WI is by taking a bus because it’s the best combination of price and speed.
· · 2:00 AM15h00St. Louis, S 15th St (Civic center)5:00 PMMilwaukee, Intermodal Station$741One-way2 transfers
Cheapest
- · · 2:00 AM15h00St. Louis, S 15th St (Civic center)5:00 PMMilwaukee, Intermodal Station$741One-way2 transfers
Fastest
AA2818+
AA403511:01 AM3h15St. Louis Lambert International Airport2:16 PMGeneral Mitchell International Airport$4051One-way1 transfer
Other options
- · +FlixBus2:00 AM16h25St. Louis, S 15th St (Civic center)6:25 PMMilwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI$741One-way2 transfers
- FlixBus+2:30 PM9h20St. Louis, S 15th St (Civic center)11:50 PMMilwaukee, Intermodal Station$821One-way1 transfer
- UA4517 · UA593310:27 AM3h16St. Louis Lambert International Airport1:43 PMGeneral Mitchell International Airport$4051One-way1 transfer
- UA2792 · UA52348:00 AM3h30St. Louis Lambert International Airport11:30 AMGeneral Mitchell International Airport$4051One-way1 transfer
- UA4395 · UA566811:35 AM3h36St. Louis Lambert International Airport3:11 PMGeneral Mitchell International Airport$4051One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from St. Louis, MO to Milwaukee, WI
Travel to Milwaukee, WI easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Milwaukee, WI.
This is compared to other travel options from St. Louis, MO to Milwaukee, WI:
A bus is $88 less than a train for this route with tickets for a train from St. Louis, MO to Milwaukee, WI costing on average $168.
A bus is $536 less than a flight for this route with tickets for a flight from St. Louis, MO to Milwaukee, WI costing on average $617.
Other travel options to Milwaukee, WI take longer:
Train takes on average 7h 19m.
Bus takes on average 9h 21m.
- Around 52 flights per day.
- Around 9 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between St. Louis, MO and Milwaukee, WI as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from St. Louis Lambert International Airport and arrive in General Mitchell International Airport.
- Trains mostly depart from St. Louis Station, St. Louis, MO and arrive in Milwaukee Intermodal Station, Milwaukee, WI.
- Buses mostly depart from St. Louis, S 15th St (Civic center) and arrive in Milwaukee, Intermodal Station.
- Travel with Greyhound, FlixBus to go to Milwaukee, WI by bus.
- Travel with American Airlines, piedmont airlines, Republic Airlines, United, skywest airlines, psa airlines to go to Milwaukee, WI by flight.
- Travel with Amtrak to go to Milwaukee, WI by train.
Travelling from St. Louis, MO to Milwaukee, WI: related information
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