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The cheapest and fastest buses from St. Louis, MO to Indianapolis, IN
Showing times and prices for Mar 01
Cheapest price
$68
Average price
$79
Fastest journey
4 h 25 m
Average duration
6 h 28 m
Buses per day
4
Distance
370 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Indianapolis, IN will cost around $79 if you buy it on the day, but the cheapest tickets can be found for only $68.
Fast buses
Of the 4 buses that leave St. Louis, MO for Indianapolis, IN on Sun, Mar 01, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 01 the direct buses cover the 370 km distance in an average of 6 h 28 m but if you time it right, some buses will get you there in just 4 h 25 m .
On Sun, Mar 01 the slowest buses will take 12 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
08:45AM4h45
St. Louis, S 15th St (Civic center)02:30PMIndianapolis, Illinois St (Greyhound Bus Station)
$681One-way
0 transfers
01:55PM4h25
St. Louis, S 15th St (Civic center)07:20PMIndianapolis, Illinois St (Greyhound Bus Station)
$721One-way
0 transfers
02:00AM4h25
St. Louis, S 15th St (Civic center)07:25AMIndianapolis, Illinois St (Greyhound Bus Station)
$811One-way
0 transfers
302 Lincoln Service · 8890 AMTRAK06:35AM12h15
St. Louis Station, St. Louis, MO07:50PMIndianapolis Station, Indianapolis, IN
$981One-way
1 transfer
01:55PM4h25
St. Louis, S 15th St (Civic center)07:20PMIndianapolis, Illinois St (Greyhound Bus Station)
$721One-way
0 transfers
02:00AM4h25
St. Louis, S 15th St (Civic center)07:25AMIndianapolis, Illinois St (Greyhound Bus Station)
$811One-way
0 transfers
08:45AM4h45
St. Louis, S 15th St (Civic center)02:30PMIndianapolis, Illinois St (Greyhound Bus Station)
$681One-way
0 transfers
302 Lincoln Service · 8890 AMTRAK06:35AM12h15
St. Louis Station, St. Louis, MO07:50PMIndianapolis Station, Indianapolis, IN
$981One-way
1 transfer
Travel Information
Compare train, bus, and flight for St. Louis, MO to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 2h 36m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $156.
Distance: 229 miles (370 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$59 Average price Cheapest | $139 Average price | $358 Average price |
5h 1m Average total duration 4h 31m Onboard + 30m Additional time* | 8h 11m Average total duration 7h 41m Onboard + 30m Additional time* | 5h 36m Average total duration Fastest 2h 36m Onboard + 3h 0m Additional time* |
Most popular bus company | Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
St. Louis, MO to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 07:25AM | Duration 4h25 | Departure days Mon, Sat, Sun | Cheapest price $53 |
Operator Amtrak | Departure Time 06:35AM | Arrival Time 07:50PM | Duration 12h15 | Departure days Mon, Sat, Sun | Cheapest price $98 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 02:30PM | Duration 4h45 | Departure days Mon, Sat, Sun | Cheapest price $53 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 07:20PM | Duration 4h25 | Departure days Mon, Sat, Sun | Cheapest price $53 |
Live departures
St. Louis, MO to Indianapolis, IN bus times
The table below shows live departures for St. Louis, MO to Indianapolis, IN buses for tomorrow, Sunday, March 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at 8:17 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:00 AM St. Louis, S 15th St (Civic center) | 4h25 | 12:25 PM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
| 302 Lincoln Service · 8890 AMTRAK | 12:35 PM St. Louis Station, St. Louis, MO | 12h15 | 12:50 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
| 2:45 PM St. Louis, S 15th St (Civic center) | 4h45 | 7:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
| 7:55 PM St. Louis, S 15th St (Civic center) | 4h25 | 12:20 AM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Indianapolis, IN by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 01
Mar 01
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Why should you book St. Louis, MO to Indianapolis, IN buses with Omio?
Greyhound as well as FlixBus offer buses services from St. Louis, MO to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Indianapolis, IN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Indianapolis, IN.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Indianapolis, IN.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Indianapolis, IN.
Journey information
Overview: Bus from St. Louis, MO to Indianapolis, IN
USAUSA
Buses from St. Louis, MO to Indianapolis, IN run on average 4 times per day, taking around 4h 31m. Cheap bus tickets for this journey start at $34 (€27) if you book in advance.
There are 3 buses per day. The earliest bus runs at 01:59, the last at 23:30. The fastest bus covers the 229 miles (370 km) distance in 4h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 229 miles (370 km) |
Average bus duration 4h 31m |
Cheapest ticket price $34 (€27) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 4h 25m |
First bus 01:59 |
Last bus 23:30 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from St. Louis, MO to Indianapolis, INYou can travel by bus between St. Louis, MO to Indianapolis, IN with Greyhound, FlixBus for as low as $34 (€27). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
12h 30m
Cheapest Price
$123 (€98)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
4h 25m
Cheapest Price
$34 (€27)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from St. Louis, MO to Indianapolis, IN
Find answers to the most common questions about traveling from St. Louis, MO to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Indianapolis, IN can start from as little as $34 (€27) when you book in advance. The average bus ticket price for St. Louis, MO to Indianapolis, IN is $59 (€47) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Indianapolis, IN is 4h 25m to travel the 229 miles (370 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Indianapolis, IN leaves at 1:59 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Indianapolis, IN leaves at 11:30 PM.
Yes, there are 3 direct buses a day from St. Louis, MO to Indianapolis, IN with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from St. Louis, MO to Indianapolis, IN, you can count on Greyhound, FlixBus for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between St. Louis, MO and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from St. Louis, MO is worth doing but not as a day trip with a journey time of 4h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Indianapolis, IN is November.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Indianapolis, IN including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Indianapolis, IN for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from St. Louis, MO to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Indianapolis, IN. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Indianapolis, IN with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Indianapolis, IN with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Indianapolis, IN with the following bus company: Greyhound, FlixBus.
popular bus stations
Popular bus stations from St. Louis, MO to Indianapolis, IN
St. Louis
Indianapolis
The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to Indianapolis.
St. Louis, S 15th St (Civic center)
information
The major bus station for arrivals in Indianapolis is Indianapolis, Illinois St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Indianapolis, Illinois St (Greyhound Bus Station) for your trip to Indianapolis from St. Louis.
Indianapolis, Illinois St (Greyhound Bus Station)
information
Indianapolis, E Washington St / N Delaware St (City/County Building)
information
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and St. Louis, MO
Most popular bus connections to Indianapolis, IN
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