4.9
4.6The cheapest and fastest buses from St. Louis, MO to Indianapolis, IN
Cheapest price
$58
Average price
$70
Fastest journey
4 h 25 m
Average duration
6 h 47 m
Buses per day
3
Distance
370 km
The best way to find a cheap bus ticket from St. Louis, MO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Indianapolis, IN will cost around $70 if you buy it on the day, but the cheapest tickets can be found for only $58.
Of the 3 buses that leave St. Louis, MO for Indianapolis, IN on Mon, Dec 01, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 01 the direct buses cover the 370 km distance in an average of 6 h 47 m but if you time it right, some buses will get you there in just 4 h 25 m .
On Mon, Dec 01 the slowest buses will take 11 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Travel Information
Compare bus, train, and flight for St. Louis, MO to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a flight which can get you there in 2h 36m. The ticket price range depends on the travel mode: a bus costs an average of €26, and a flight costs an average of €84.
Distance: 229 miles (370 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€45 Average price Cheapest | €98 Average price | €223 Average price |
5h 25m Average total duration 4h 55m Onboard + 30m Additional time* | 8h 11m Average total duration 7h 41m Onboard + 30m Additional time* | 5h 36m Average total duration Fastest 2h 36m Onboard + 3h 0m Additional time* |
Most popular bus company | Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
St. Louis, MO to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 07:25AM | Duration 4h25 | Departure days Fri, Sun | Cheapest price $46 |
Operator Amtrak | Departure Time 06:35AM | Arrival Time 07:50PM | Duration 12h15 | Departure days Fri | Cheapest price $110 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 02:30PM | Duration 4h45 | Departure days Fri, Sun | Cheapest price $46 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 07:20PM | Duration 4h25 | Departure days Fri, Sun | Cheapest price $47 |
Live departures
St. Louis, MO to Indianapolis, IN bus times
The table below shows live departures for St. Louis, MO to Indianapolis, IN buses for today, Sunday, November 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:00 AM St. Louis, S 15th St (Civic center) | 4h25 | 12:25 PM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
| 2:45 PM St. Louis, S 15th St (Civic center) | 4h45 | 7:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
| 7:55 PM St. Louis, S 15th St (Civic center) | 4h25 | 12:20 AM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Indianapolis, IN by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 01
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Dec 06
Dec 07
Journey information
Overview: Bus from St. Louis, MO to Indianapolis, IN
USAUSA
Buses from St. Louis, MO to Indianapolis, IN run on average 4 times per day, taking around 4h 55m. Cheap bus tickets for this journey start at $32 (€26) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:50, the last at 23:30. The fastest bus covers the 229 miles (370 km) distance in 4h 25m.
Distance 229 miles (370 km) |
Average bus duration 4h 55m |
Cheapest ticket price $32 (€26) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 4h 25m |
First bus 00:50 |
Last bus 23:30 |
Bus providers: Greyhound, FlixBus from St. Louis, MO to Indianapolis, INYou can travel by bus between St. Louis, MO to Indianapolis, IN with Greyhound, FlixBus for as low as $32 (€26). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from St. Louis, MO to Indianapolis, IN
Find answers to the most common questions about traveling from St. Louis, MO to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from St. Louis, MO to Indianapolis, IN, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from St. Louis, MO to Indianapolis, IN
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and St. Louis, MO
Most popular bus connections to Indianapolis, IN
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